Tuning Solution for the X-Series QTOF System Is Used Too Quickly

日付: 03/21/2017

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For research use only. Not for use in diagnostic procedures.

Issue Description

The tuning solution for the X-Series QTOF Systems is consumed very quickly, and no signal or only a very low signal is obtained on the mass spectrometer during tuning.


Quickly emptied tuning solution bottles (1 bottle in less than 1 week) are likely caused by a leak in the Calibrant Delivery System (CDS) plumbing and may be easily fixed by checking the tightness of connections behind the front panel of the X-Series instrument.

  1. Deactivate hardware profiles.
  2. Remove LC tubing and Calibrant Delivery System (CDS) tubing from TurboV™ source.
  3. Remove TurboV source.
  4. Gently pull the front cover to open and inspect all of the tubing connections behind the front panel leading from the tuning solution bottles to the CDS valves and eventually to the MS. 
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