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SCIEX Triple Quad 7500 LC-MS / MSシステム-QTRAP Readyは、LC-MS / MSの革新と感度の新時代を切り開きます。 感度、スループット、耐久性、頑健性の限界を超越。 このイノベーションを発見する先駆けとなってください。

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比類なき

SCIEX Triple Quad 7500システムにより比類ない感度向上を実現。 今まで、検出できなかった化合物の分析ができ、優れた精度でより低いレベルの定量が可能となります。

独創性

汚れた複雑なサンプル分析を可能にし、ラボ機能を拡張。 新設計されたD Jetイオンガイドにより、マトリックスの影響により検出できなかった分析対象物の特性評価が可能となります

生産性

より低いレベルかつより多くの微量分析物の定量を実現。サンプルの前処理を簡素化し、OptiFlow Proイオンソースによりサンプル量を減らすことができます。 統合されたE Lensテクノロジーにより多くのイオンをサンプリングし、ESI分析をさらに拡張。

比類なき

SCIEX LC-MS/MSシステムの中で最高レベルの感度をSCIEX Triple Quad 7500システムで実現。この革新により、クルードサンプルや複雑なサンプルを高感度に定量し、研究を進め、ワークフローの拡大を可能とします。最大6桁の線形ダイナミックレンジを備えた簡素化されたワークフローを実現。

独創性

Turbo Vイオンソースの進化。 SCIEX Triple Quad 7500システムに搭載されたOptiFlow Proソースにより、クルードサンプルや複雑なサンプルに含まれる対象物質を検出します。OptiFlow Proソースで採用されたE-Lensテクノロジーにより重要なイオンの質量分析計への取り込みを改善。 OptiFlow Proソースのモジュールにより、調整することなく、迅速に低流速から高流量への切り替え、ESIからAPCIへの切り替えが可能。D Jetイオンガイドにより分析感度が飛躍的に向上。 質量分析計へより多くのイオンを取り込むようオリフィスのサイズを大径化し、サンプルのプロファイルをより正確に得ることができます。 イオンガイドのユニークなデザインにより、ESIスプレーからイオンをより多く保持し、取り込みます。

生産性

ワークフローをこの高感度装置に移行することで、目に見えて生産性が向上します。より多くの分析を可能とする革新により、これまでのシステムでは確認が難しい微量化合物の検出が可能となります。 次世代の質量分析計プラットフォームのSCIEX OSにより、 従来のソフトウェアの特徴と機能は、視覚的な支援とコンポーネントによって補完され、迅速で正確で信頼できるデータレビューを可能にします。

SCIEX OS ソフトウエア

新しい直感的な形式でデータを解析・表示。新しい直感的な形式でデータを解析・表示。 1つのソフトウェアプラットフォームで、制御、取得、解析、詮索、レポートを全て実行。

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Enabling new levels of quantification
Using the SCIEX 7500 System, powered by SCIEX OS Software.

QTRAP Ready

シンプルなアップグレードパスにより、このシステムはQTRAPシステムにアップデートできます。 従来のMRMワークフローとEnhanced Product Ionスキャンを組み合わせることで、取得したデータの信頼性を向上が可能となり、MRM3ワークフローは、マトリックス干渉を通じて定量化レベルを向上させることができます。

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E LENS テクノロジー

オリフィス周囲により強い勾配を与えることで貴重で限られたサンプルを保護します。 E Lens Technologyを搭載したOptiFlow Proイオンソースにより、SCIEX Turbo Vイオンソースのパワーと効率が強化され、ESIプルームのオリフィス透過性を改善しております。

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イオンソース

分析用途に応じた低流速から高流速へ高速で切り替え。OptiFlow Proソースは、新しいモジュール機能と共に、伝説的ともいえるTurbo Vソースの信頼性と効率性を兼ね備えています。

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D JET イオンガイド

エレクトロスプレーイオン化法(ESI)で生成されたイオンをより多く取り込み、既存のテクノロジーよりも重要なイオンをより多く保持します。 D Jet イオンガイドはサンプルを濃縮し、ガス分子と中性イオンの除去が可能となります。

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検出

すべてのSCIEX装置の中で、より高感度の定量化を実現。 イオンレールの正確で頑健なエンジニアリングにより、ワークフローに極めて重要なイオンに焦点を当て、一貫 して再現可能な分析を何度でも行うことができます。

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E LENSテクノロジー

イオンソース

D JET イオンガイド

DETECTION

QTRAP Ready

Therapeutics are always going to be necessary...Now with this new SCIEX 7500 System, we have another level of sensitivity. SCIEX has again set the bar.

SHANE NEEDHAM
Chief Founding Scientist
Alturas Analytics, Moscow, ID

You have to look for different substances in water and some substances are very difficult to measure because of the sensitivity of current instruments. Before now we didn’t know they were in the water because the methods weren’t sensitive enough.

BERNARD BAJEMA
Project Leader
Vitens, Netherlands

The drive to improve pesticide detection limits is not just from legislation, but also from the demands of consumers. Faster and more sensitive technology prepares us for those situations to allow us to get lower and we will if required.

WIM BROER
Manager, Science and Development
Nofalab, Netherlands

When an instrument is sensitive, we can do direct water injection. We don’t need sample prep to concentrate the samples, that is the big advantage of sensitive machines.

RONNY BOSCH
Senior Analyst
Vitens, Netherlands

SENSITIVITY GAINS FOR THE EVOLUTION OF ROUTINE BIOANALYSIS

The rapid advancement of the drug pipeline demands sensitivity to allow a more complete pharmacokinetic characterization of low-dose drug candidates, below detection limits. The SCIEX 7500 System will enable pharmaceutical researchers to continue to explore lower dosage, higher efficacy compounds, and improve the efficiency of routine bioanalysis.

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HIGH SENSITIVITY PEPTIDE QUANTIFICATION WORKFLOW

Quantification of peptide/protein therapeutics in biological matrices is crucial for therapeutic development. Download the technical note that demonstrates a robust method using the SCIEX 7500 System to quantify a series of surrogate peptides in rat plasma at ultra-low LLOQs —5 to 39 fmol/mL.

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ULTRA-SENSITIVE QUANTIFICATION OF INTACT PEPTIDE HORMONE IN RAT PLASMA

Quantifying intact peptide hormone analogs is challenging for because of low ionization and CID fragmentation efficiency related to the high molecular weights, low concentrations in matrices that require ultra-high assay sensitivity, and endogenous inferences from natural intact peptide hormones. Enter the SCIEX 7500 System. Read more about the sensitive LC-MRM method to quantify intact peptide hormones in rat plasma.

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IMPROVED LC-MRM WORKFLOW FOR CYCLIC PEPTIDE QUANTIFICATION ON NATRIURETIC PEPTIDE FAMILY

Quantifying trace level cyclic peptides in biological matrices is extremely challenging. The SCIEX 7500 System can offer outstanding reproducibility, precision, accuracy, and linearity to ease these challenges. Download this ultra-sensitive MRM based cyclic peptide quantification workflow.

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ENHANCING THE SENSITIVITY OF PEPTIDE QUANTIFICATION FOR THE TARGETED HOST CELL PROTEINS ANALYSIS

There are important requirements for the quantitative measurement of host cell proteins (HCP) across the entire development paradigm. Learn about the targeted high sensitivity, analysis throughput, robustness and multiplexing capability approach using the SCIEX 7500 System.

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BROAD LIPID QUANTIFICATION USING A HIGH- THROUGHPUT TARGETED LIPIDOMICS METHOD

The complexity of the lipidome is very high with a huge diversity in lipid molecular species making comprehensive quantitative profiling challenging. Download this technical note to find out about a targeted MRM assay approach which enables quantification of a broad array of different lipids at the molecular species level using the SCIEX 7500 System.

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HIGHLY-SENSITIVE PESTICIDE ANALYSIS IN BABY FOOD

Detecting and quantifying pesticide residues in food remains a moving target as food regulations drive the pursuit of lower limits of quantification. This work demonstrates the high sensitivity of the SCIEX 7500 System in quantifying 209 pesticides, easily achieving sub-ppb detection limits with a very small injection volume.

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PRECISE TESTING OF PESTICIDES IN FOOD USING THE SCIEX 7500 SYSTEM

The global scale of pesticide use, its impact on food safety and authenticity regulations have led to the need for sensitivity analysis that can achieve trace levels. Download the technical note to learn more about how the SCIEX 7500 System offers sensitivity, robustness and accuracy with 700 compounds achieving limits low as 0.2 ng/mL.

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THE DIRECT AQUEOUS ANALYSIS OF PESTICIDES AND PPCP's, IN DRINKING AND BOTTLED WATER USING THE SCIEX 7500 SYSTEM

Drinking water analysis is subjected to extremely low and rigid prescribed consent values (PCV) for determinands, including pesticides, pharmaceuticals and personal care products. In collaboration with Vitens Water Company, we demonstrated the sensitivity levels of the SCIEX 7500 System for low-level quantification across a relatively large suite of 431 determinands.

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FUTURE-PROOFING CANNABIS ANALYSIS WITH THE SCIEX 7500 SYSTEM

As the cannabis market emerges globally, more stringent and lower level pesticide regulations may come into force. The SCIEX 7500 System shows its levels of sensitivity across a broad suite of regulated pesticides coupled with ruggedness and robustness for continued analysis of cannabis extracts.

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HIGH-SENSITIVITY DETECTION OF FORENSIC DRUG PANEL IN HUMAN WHOLE BLOOD

In a forensic laboratory, the ability to accurately quantify large panels of analytes in complex biological matrices over a wide range of concentration is challenging and often requires dilution of the samples to bring them within the calibration range of the instrument. In this technical note, the SCIEX 7500 System demonstrates exceptional performance in speed, linear dynamic range and sensitivity to overcome this challenge, quantifying a panel of 49 drugs in human whole blood.

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