Molecular Ion Not Appearing during Compound Optimization｜質量分析計・LC-MS/MSシステムのSCIEX

For research use only. Not for use in diagnostic procedures.

Issue Description

When optimizing an analyte during compound optimization by direct infusion, the molecular ion is not seen, nor are any ions of note, in the MS 1 scan.
 

Resolution

Adding mobile phase to the analyte or increasing its concentration during compound optimization may help improve ionization.