SCIEX ASMS 2016 発表ポスター 一覧

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低分子化合物

ペプチド・タンパク質・核酸定量

バイオ医薬品の特性解析

プロテオミクス

メタボロミクス/リピドミクス

低分子化合物
# 1Allopurinol 分析
タイトルApplication of TOF MS instrument in Bioanalysis – A Case Study
著者Shaokun Pang1; Weixing Sun2; Adrien Musuku2; Xavier Misonne*1
所属1SCIEX; 2Pharmascience
 
# 2薬物相互作用
タイトルEmerging Bioanalytical Tool to Characterize Drug and Drug-Products of Biotherapeutics
著者Jinal Patel*1; Mark Cancilla2; Xiang Yu2; Alina Dindyal-Popescu1; Gordon Payne1; Eva Duchoslav1; Suma Ramagiri1
所属1SCIEX; 2Merck & Co., Inc.
 
# 3高分解能スクリーニング
タイトルHigh Throughput Screening- ADME; Transitioning from Triple Quadrupole to High Resolution Accurate Mass Spectrometry
著者Jason Causon1; Graeme Clark2
所属1SCIEX UK; 2Cyprotex, UK
 
# 4高分解能定量
タイトルUtilizing High Resolution Accurate Mass Spectrometry for Quantification, MRMHR and SWATH® Acquisition Workflows
著者Jason Causon1; Lee Mendil2; Donna-Michelle Smith2; Neil Devenport*1; Thomas Knapman1; Milla Neffling1
所属1SCIEX UK; 2CRUK Cambridge Institute - University Of Cambridge, UK
 
# 5バイオマーカー定量
タイトルHighly Sensitivity and Reproducible MRM-Based Quantitation of Follicle Stimulating Hormones (FSH) in Human Plasma Using the QTRAP® 6500 System
著者Faraz Rashid*1; Rahul Baghla1; Prashant Kale2; Manoj Shukla2; Milin Shah2; Dipankar Malakar1; Anoop Kumar1; Manoj Pillai1
所属1SCIEX India; 2Lambda Therapeutic Research Ltd, India
 
# 6バイオマーカー定量
タイトルHighly Sensitive LC-MS/MS Method for the Quantification of Fluticasone Propionate in Human Plasma, Feasible for Reinjection and Repeat Analysis
著者Jeyan Albert*1; Praveen V. Kumar2; Manoj Bob2; Ravisekhar K2; Anoop Kumar1; Manoj Pillai1
所属1SCIEX India; 2Lupin Bioresearch Center, India
 
# 7バイオマーカー定量
タイトルHighly Sensitive and Selective Bioanalytical Quantitation Method forDocetaxelin Human Plasma
著者Santosh Kapil Kumar Gorti*; Aman Sharma; Jeyan Albert; Anoop Kumar; Manoj Pillai
所属SCIEX India
ペプチド・タンパク質・核酸定量
# 1BioBAソリューション
タイトルAn Automated Sample Extraction and Processing Method Combining Ligand Binding and Mass Spectrometry Analysis for Biotherapeutics Quantitation 
著者Ian Moore
所属SCIEX
 
# 2核酸医薬分析
タイトルAnalysis of Synthetic Nucleotides using Accurate Mass and Ion Mobility 
著者Cynthia Sanderson*; Sushmit Maitra; Keith Goodman
所属SCIEX
 
# 3マイクロLCバイオ医薬品定量
タイトルImproving the Sensitivity for an Immunocapture LC-MS Assay of Infliximab in Rat Plasma Using Trap-and-Elute MicroLC-MS 
著者Remco van Soest*; Lei Xiong
所属SCIEX
 
# 4CESI-MS/MSペプチド定量
タイトルQuantitation of Nucleotides and Nucleosides without Derivatization Using Transient Isotachophoresis-Capillary Electrophoresis Coupled to Tandem Mass Spectrometry 
著者Jose Luis Gallegos Perez
所属SCIEX
 
# 5CESI-MS/MSペプチド定量
タイトルAn Alternative and More Sensitive Approach for the Analysis Ofneuropeptides in Biological Samples 
著者Stephen J. Lock1; Edna Betgovargez*2
所属1SCIEX UK; 2SCIEX
 
# 6Peg化バイオ医薬品定量
タイトルQuantitation of Pegylated Drug Conjugate Interferon Alfa-2b in Human Serum using the QTRAP® 6500 System
著者Faraz Rashid1; Dipankar Malakar1; Anoop Kumar*1; Manoj Pillai1; Praveen Kumar Vittala2; Manoj Bob2; Ravisekhar K2
所属1SCIEX India; 2Lupin Bioresearch Center, India
バイオ医薬品の特性解析
# 1APTSラベル化糖鎖解析
タイトルHigh Resolution CESI-MS Analysis of APTS-labeled N-glycans of Biopharmaceutical Interest 
著者Bryan Fonslow2; Marton Szigeti1; Andras Guttman*2
所属1University of Debrecen, Hungary; 2SCIEX
 
# 2糖鎖の精密解析
タイトルAnalysis of Derivatized Glycans using Differential Mobility Spectrometry 
著者Cathy Lane1; J.C. Yves LeBlanc2; J. Larry Campbell*2
所属1SCIEX UK; 2SCIEX
 
# 3特性解析一般
タイトルComplete Characterization of Biotherapeutic Proteins by Automated Data Processing on High Resolution Accurate Mass Spectrometry with SWATH® Acquisition 
著者Milla Neffling*; Yang Shi; Dominic Gostick; Doug Simmons
所属SCIEX
 
# 4HCP(宿主細胞由来タンパク質)解析
タイトルHost Cell Protein Analysis by Microflow-LC High Resolution SWATH-MS of Vaccine Samples Under Development 
著者Søren Heissel*1; Milla Neffling2; Rikke Raaen Lund3; Thomas Kofoed3; Marie Grimstrup3; Nick Morrice2; Anne Fich Holmbjerg4; Max Per Kristiansen4; Ingrid Kromann4; Peter Højrup1; Ejvind Mørtz3
所属1Department of Biochemistry and Molecular Biology, University of Southern Denmark, Denmark; 2SCIEX UK; 3Alphalyse A/S, Denmark; 4Statens Serum Institut, Denmark
 
# 5バイオ医薬品のミドルダウン解析
タイトルBiosimilar Insulin Characterization: Top/Middle/Bottoms Up Approaches 
著者Rishikant Gupta1; Mithun Bhatt1; Annu Uppal*2; Manoj Pillai2; Archana Krishnan1; Sanjay Sonar1
所属1Biogenomics, India; 2SCIEX India
 
# 6S-S結合解析
タイトルOn-line Disulfide Cleavage for Structural Characterization 
著者J.C. Yves LeBlanc; Tanya Gamble*
所属SCIEX
プロテオミクス
# 1SWATHプロテオミクス
タイトルLarge-Scale Quantitative Measurements of Rat Brain Hippocampus Membrane Proteome in Prolonged Simulated Microgravity Model by 2D-SWATH® Mass Spectrometry 
著者Peibin Qin*1; Yun Wang2; Lihai Guo1; Yongqian Zhang2; Wenhai Jin1; Yulin Deng2
所属1SCIEX China; 2School of Life Science, Beijing Institute of Technology, China
 
# 2SWATHプロテオミクス
タイトルUnderstanding the Square-Wave Nature of Q1 Isolation for Data-Independent SWATH® Acquisition 
著者Randy J. Arnold*; Leroi Desouza; Christie Hunter; Patrick Pribil
所属SCIEX
 
# 3SWATHプロテオミクス
タイトルExtending the Depth of Coverage in SWATH® Acquisition with Deeper Ion Libraries 
著者Joerg Dojahn*1; Nick Morrice2; Christie Hunter3
所属1SCIEX Germany; 2SCIEX UK; 3SCIEX
 
# 4SWATHプロテオミクス
タイトルThe Use of Smaller Q1 Isolation Windows Improves Reproducibility in SWATH® Acquisition Based Protein Quantification Even at Higher Spectral Acquisition Rate 
著者Dipankar Malakar*; Faraz Rashid; Manoj Pillai
所属SCIEX India
 
# 5マイクロフローSWATHプロテオミクス
タイトルAccelerating Data Independent Acquisition with Microflow Chromatography 
著者Christie Hunter*1; Nick Morrice2
所属1SCIEX; 2SCIEX UK
 
# 6CESI-MS/MSプロテオミクス
タイトルA New Approach to the Analysis of Intact Major Urinary Proteins (MUPs) from Mouse Urine by CESI-MS 
著者Stephen J. Lock*1; Robert J. Beynon2; Guadalupe Gomez-Baena2; Edna Betgovargez3
所属1SCIEX UK; 2Centre for Proteome Research, Institute of Integrative Biology, University of Liverpool, UK; 3SCIEX
 
# 7Cytochrome SWATHプロテオミクス
タイトルComprehensive Relative Quantification of the Cytochromes P450 by Micro-LC and SWATH® Acquisition and Data Processing Using Cloud Computing 
著者Rosalind E. Jenkins1; Sibylle Heidelberger2; Thomas Knapman2; Francesco Brancia2; Neil Kitteringham1; Kevin B. Park1; Mark Cafazzo*3
所属1MRC Centre for Drug Safety Science, UK; 2SCIEX UK; 3SCIEX
 
# 8マイクロフローSWATHプロテオミクス
タイトルImproving Speed and Robustness of DIA Quantitation Using Longer microLC Columns 
著者Remco van Soest; Christie Hunter; Gavin Fischer*
所属SCIEX
メタボロミクス/リピドミクス
# 1リピドミクス
タイトルSeparation of Positional Isomers of PAHSAs Using LC-MS/MS Coupled with Differential Ion Mobility Mass Spectrometry 
著者Shaokun Pang*1; Liling Liu2; Xiaorong Liang2; Amos Baruch2; Leo Wang1; Brian Dean2; Yuzhong Deng2
所属1SCIEX; 2Genentech Inc.
 
# 2リピドミクス
タイトルSphingolipid Profiling Using Robust and Sensitive LC-MS-MS Method 
著者Shachi Saluja1; Dipankar Malakar2; Manoj Pillai2; Avinash Bajaj1; Ujjaini Dasgupta*3
所属1Regional Centre for Biotechnology, India; 2SCIEX India; 3Amity University, India
 
# 3メタボロミクス
タイトルWhat Are We Eating? Differential Metabolomic Profiles Reveal an Insight into Our Dietary Habits 
著者Paul Clemens*; Baljit Ubhi
所属SCIEX
 
# 4リピドミクス
タイトルDetermination of Limaprost, an Analogue of PGE1 in Human Plasma by QTRAP® 6500+ and SelexION®+ Technology 
著者Gangyi Liu*1; Chao Zhang2; Wenhai Jin2
所属1Xuhui Center Hospital, China; 2SCIEX China
 
# 5リピドミクス
タイトルEvaluation of High Speed, High Resolution Data Independent Acquisition for the Analysis of Metabolomic Flux, Kinetics and Pathway 
著者Loren Y. Olson*; Baljit Ubhi
所属SCIEX
 
# 6リピドミクス
タイトルAccelerating Lipid Profiling Acquisition Strategies Using Differential Mobility Spectrometry and SWATH® Data Collection 
著者Eva Duchoslav*1; Brad T. Patterson2; J. Larry Campbell1; J.C. Yves LeBlanc1
所属1SCIEX; 2SCIEX Australia
 
# 7メタボロミクス
タイトルA Novel Targeted Metabolic Profiling Workflow for Simultaneous Reverse Phase and HILIC microflow LC-MS/MS Analysis 
著者Daniel M. Warren*; Jeffrey D. Miller
所属SCIEX
 
# 8リピドミクス
タイトルResearch into Lysosomal Storage Metabolism Using Plasma Lipid Characterization by LC-MS/MS 
著者Sibylle Heidelberger*1; Daniel Blake1; Rachel Webster2; Karen Smith2; Martin Roch2
所属1SCIEX UK; 2Queen Elizabeth Hospital Birmingham, UK
 
# 9リピドミクス
タイトルDifferential Complex Lipid Plasma Profiles Reveal Perturbations in Preeclampsia 
著者Baljit Ubhi*1; Katherine Williams2; Susan Fischer2
所属1SCIEX; 2UCSF
 
# 10Lipidyzer™プラットフォーム
タイトルSoftware: Nexus Point of a Targeted Lipid Analyzer 
著者Pauline J. Vollmerhaus*1; Baljit K. Ubhi1; Sarada Tanikella2; Peter Zhu2; Corey D. DeHaven2
所属1SCIEX; 2Metabolon
 
# 11メタボロミクス
タイトルCarbonic Anhydrase Inhibitory Potential of Lagenaria siceraria Stand and Identification of Its Bioactive Compounds - An LC-MS/MS Approach 
著者Joydeb Chanda*1; Pulok K. Mukherjee1; Rajarshi Biswas1; Dipankar Malakar2; Manoj Pillai2
所属1School of Natural Product Studies, Department of Pharmaceutical Technology, Jadavpur University, India; 2SCIEX India