What is the Maximum Sampling Speed of the Echo® MS System?

For research use only. Not for use in diagnostic procedures.

Answer

There are two modes for the Echo® MS system, normal and fast. The normal mode maximum sampling speed is 1 sample/s. In this mode, 4 MRM transitions/well can be reliably acquired for a single droplet ejection with the same number of transitions monitored in adjacent wells because the peaks are baseline resolved (under the recommended running conditions). In fast mode, the maximum sampling speed is 3 samples/s. In fast mode it is also possible to reliably acquire 4 MRMs/well for a single droplet ejection, however you cannot monitor the same transitions in adjacent wells because the peaks from the fast ejection cycles are not baseline resolved (under the recommended running conditions). In normal mode, the typical time to complete a 384-well plate is less than 10 min; and for a 1536-well plate, it is less than 22 min.