ExionLC™シリーズUHPLC

LC-MS向け標準フローHPLCソリューション

SCIEXの質量分析装置とシームレスに統合するよう設計されたExionLC標準フローHPLCおよびUHPLCシステムは、ルーチンまたは複雑なLC-MS分析に必要なスピード、感度、分解能、信頼性をご提供します。

モデルの選択

ExionLC AC:

幅広いアプリケーションに対応できる手頃なシステムです。 HPLCとUHPLCの両性能を備えたExionLC ACは、信頼性、頑健性の高いルーチン分析向けソリューションです。

ExionLC AD (下図に表示):

このシステムは、キャリーオーバーがほとんどなく、非常に要求の厳しい分析条件下で世界クラスのパフォーマンスをお届けできる完全なUHPLC性能を備えています。

ExionLC™シリーズUHPLC
主な仕様

流量設定範囲

0.0001 ~10.0 mL/min

HPLC/ UHPLCの耐圧

9,500~18,850 PSI

超低キャリーオーバー

革新的な送液設計、複数のリンス液を選択可能

ハイスループット性能

384 ウェルMTPで最大768サンプル (ラックチェンジャーオプションを使用すると12プレート/トレイまで拡張可能)

柔軟なカラムオーブンの選択

コンパクトな2カラムオーブンまたは6カラムを選択可能

オプションアクセサリー

マルチプレートオートサンプラー(ADのみ)、ラックチェンジャー、オプション検出器

お客様のニーズに合わせたLCソリューション

皆様のラボには独自の分析要件があります。SCIEXの目標は、お客様のニーズを満たすLC-MSソリューションをお届けすることです。 ExionLC™シリーズの頑健で信頼性の高いHPLC / UHPLCシステムは、幅広い性能と柔軟性をご提供することができます。

UHPLC/HPLCパフォーマンスのパワー

40年以上にわたる信頼されるLC-MSの技術革新とサービスに支えられたExionLCは、メソッド開発からルーチン分析まで、24時間年中休みなく最も過酷なアプリケーションに取り組むための汎用性、再現性、堅牢性を備えています。

ExionLC AD

信頼性の高い定量

ExionLC ADは、正確な注入量とほぼゼロのキャリーオーバーで、定量をスムーズに進めるのにお役に立ちます。

優れた再現性

流量精度<0.06%で真度が2%未満により、日々の分析に求められる十分な分析真度および精度が得られます。

煩わしいアップデートは必要ありません

簡便なメソッド開発、サンプル前処理の自動化、またはスループットの向上を可能にする幅広いオプションで機能の拡張を図ります。

ExionLC AC

より高いパフォーマンスをより少ないコストで

ExionLC ACは、手頃な価格でHPLC / UHPLCの分離性能を備えています。

より良い結果をより速く

再現性のある保持時間と感度により、正確な定量が可能になり、信頼性の高い結果が得られます。

非常に高い柔軟性

ExionLCは複数のコンポーネントや構成をサポートすることができ、変化するラボのご要望に応えることができます。

主な仕様 ExionLC AD ExionLC AC
UHPLC/ HPLCの耐圧 18,500 PSI (1300 bar) 9,500 PSI (660 bar)
超低キャリーオーバー 最大0.0015% < 0.005%
冷却オートサンプラー 直接冷却、4~40°C
(指定条件下)
直接冷却、4~40°C
(指定条件下)
カラムオーブンの温度制御範囲 室温 +5° C~150°C、2本のカラム収納可能
(AC カラムオーブンにも対応)
室温 -10° C~85°C、6本のカラム収納可能
(AD カラムオーブンにも対応)
使用pH範囲 1-9(標準)
1-14(オプション)
1-14

アプリケーションの選択

医薬品・バイオ医薬品

信頼性の高いより迅速な意思決定を行い、より効果的で安全な治療用医薬品を開発するのにお役に立ちます。

食品・飲料検査

世界へ供給される食品および飲料を検査し、その安全性を守るためのソリューションをご提供することができます。

法中毒検査

完全な法中毒検査ソリューションが、結果の完全性を支持するのに役立ちます。

ライフサイエンス研究

重要な遺伝子、タンパク質、脂質、代謝物を同定し、研究のペースを加速するのにお役に立ちます。

ExionLCのカスタマイズ

モジュール式コンポーネントなら、システムをアップデートし、変化するご要望に対応することができます。 カラム切り替えバルブを追加し、2台のポンプを追加すると、オンラインSPEを実行することができます。 自動サンプル希釈またはオンラインmicroSPE用に、PALオートサンプラーを追加することができます。

溶液選択バルブ(切り替えバルブ)

最大3つの異なるポンプから、チャンネルごとに2種類の移動相溶液を選択することができます。

UV検出器

タイムプログラム可能な波長切り替えにより、高い感度で選択的に測定可能です。

ラックチェンジャー

ACまたはADシステムに、最大12の冷却サンプルトレイまたはバイアルラックを追加することができます。

PDA 検出器

微量な濃度レベルでのID、定量、純度分析向けの優れたオプションです。

マルチプレートオートサンプラー

324 検体x 1.5 mLバイアル、または96や384検体用の6マイクロタイタープレートで容量を拡張することができます。

PAL オートサンプラー

PAL RSIまたはPAL RTCオートサンプラーを追加して生産性を向上させることができます。

関連資料

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SCIEX LC-MS/MS 在药典生物药中的应用方案

ExionLC™ AD SeriesSpecifications

Nitrosamines impurity analysis using SCIEX QTRAP® 4500 LC-MS/MS System

Determination of Beta-agonist Residues in Meat

Drug Impurity Analysis Solution

Catalogue of Literatures on target lipidomics using Triple Quad QTRAP mass spectrometry (Volume 1)

Catalogue of Literatures on Metabolomics using SCIEX mass spectrometry (Volume 1)

Determination of Sulfonamide Residues in Chicken

Folder for The Flyers of Food Safety Monitoring Holistic Solution

Food Compendium 2018

SCIEX Triple Quad™ 3500 System compendium

Catalogue of Literatures on Traditional Chinese Medicine (Volume 1)

Targeted analysis of extractables/leachables in drug products, containers and closuure systems

Quantitation on the SCIEX QTRAP 4500 LC-MS/MS System with the ExionLC AD System

Single-Injection Screening of 664 Forensic Toxicology Compounds Using an Innovative Benchtop High Resolution Mass Spectrometer

Ultra-Sensitive Forensic Analysis Workflow of Cocaine andIts Metabolites in Hair Samples Using LC-MS/MS

Peptide mapping analysis of etanercept – a highly glycosylated dimeric fusion protein

Characterization of a multi-specific antibody therapeutic with peptide mapping

Comparative analysis of intact AAV8 capsid proteins derived from SF9 and HEK293 cell lines

High-Sensitivity Detection of Forensic Drug Panel in Human Whole Blood

Compliant attribute monitoring for biopharmaceutical product quality attributes employing intact mass analysis

Fast and simultaneous analysis of ethanol metabolites and barbiturates using the QTRAP® 4500 LC-MS/MS system

Highly sensitive LC-MS/MS workflow for targeted quantification of host cell proteins

Potency Analysis in Hemp and Cannabis Products using a Single-Dilution Combined LC-UV-MS/MS Approach

Highly Selective and Sensitive Method for Quantification of Nitrosamines in Valsartan Drug Substance

LC-MS/MS Analysis of Emerging Food Contaminants

Intact Analysis of Antibody Drug Conjugates

Comparative peptide mapping between two manufacturers of Trastuzumab using the X500B QTOF System

Rapid DUID Screening of 17 Drugs of Abuse in Plasma and Saliva

Extractables and Leachables Analysis from Laboratory Tubing

Método LC-MS/MS de cambio de polaridad cuantitativa para pesticidas PPCP en muestras de agua ambiental

RUO-MKT-02-5388-A Rapid and Sensitive Analysis of Antibiotics in Children’s Urine Using the X500R QTOF System

Highly Sensitive LC-MS/MS Method for Quantification of Barnidipine in Human Plasma

Authentication and Geographical Origin Analysis of Plant-Derived Edible Oil Using the SCIEX X500R QTOF System

A New Level of Compliant-Ready Intact Biotherapeutic Protein Quantitation using Reconstructed Masses

Comprehensive Analysis of Low Abundant Mannose Glycopeptides in Peptide Mapping of Adalimumab

Streamlined Unknown Screening for Postmortem Analysis Using SWATH Acquisition

Isotopic Resolution of Chromatographically Separated IdeS Subunits Using X500B QTOF System

Microsoft Word - RUO-MKT-02-7052-A - Technote - High Throughput Platform for Confident Identification and Quantitation of Organic Explosives.docx

Next Generation Quality Control in Pharma Applications

Multi-panel detection of drugs and drug metabolites in hair samples using a comprehensive extraction method

Isotopically Resolved Subunit Analysis for Tracking Protein Therapeutic Stress Studies

Rapid and Sensitive Analysis of a 93-Compound Forensic Panel in Urine using the QTRAP/Triple Quad 4500 LC-MS/MS System

HRAMS Assay for Trastuzumab

Rapid, sensitive analysis of sphingolipid variant profiles with simplified sample extraction

Confirmation of Contaminants in Water Using SCIEX Triple Quad™ 5500+ LC-MS/MS System − QTRAP® Ready and SCIEX OS-Q Software

Elevating the Forensic Laboratory Performance

Rapid Identification and Quantification of Performance-Enhancing Stimulants in Human Urine Using High-Resolution Mass Spectrometry

Efficiently Designed Workflows Provide Accurate Results in Forensic Analysis of THC-COOH in Hair

Increased Throughput for ADME Studies Using the SCIEX ExionLC� AD UHPLC System

Cannabis for Per Se Law Testing in Whole Blood using theSCIEX Triple Quad QTRAP 4500 LC-MS/MS System

Quantitative Amino Acid Analysis in Cell Culture Media Using SWATH Acquisition

No Slide Title

Chemovar Typing of Cannabis Strains with MarkerView and SCIEX X500R QTOF System

Unknown Screening_X500R QTOF SCIEX OS_food_SCIEX_RUO-MKT-02-3761-A.docx

Detection-of-Intact-Antibody-Impurities-using-X500B.pdf

Two Nontargeted Screening Approaches for Examination of Drinking Water During Treatment

Rapid Analysis of Genotoxic Nitrosamines

Elucidation and tracking of charge variants in antibodies: combining ease-of-use with gain in information

Evaluation of Critical Attributes on Different Lots of Adalimumab Using BPV Flex Software 1.0.1

Improving throughput using the ekspert™ ultraLC system

Highly Selective and Sensitive Method for Quantification of Nitrosamines in Valsartan Drug Substance

The Quantitative Power of SCIEX Triple Quad and the QTRAP® 6500+ LC- MS/MS System for the Bioanalysis of Biotherapeutics

Fast Screening Method for 86 Forensic Analytes in Human Urine QTRAP 4500

Identification and quantitation_X500R QTOF SCIEX OS_food_SCIEX_RUO-MKT-02-3760-A.docx

Detection of Growth Hormone-Releasing Peptides in Dried Blood Spots: Workflow for Anti-Doping Analysis

Detection of Fentanyl Analogs and Novel Synthetic Opioids in Hair

Forensic Authentication of Hemp-Derived Products Using a Dual Mass Spectrometry-UV Detection Approach

Confirmación de contaminantes en el agua utilizando el sistema SCIEX Triple Quad™ 5500+ LC-MS/MS - QTRAP® Ready y el software SCIEX OS-Q

Characterization of adeno-associated virus capsid proteins with peptide mapping

Rapid Identification and Quantification of Novel Psychoactive Substances in Human Whole Blood Using SWATH® Acquisition

Separation of Bile Acid Isomers with Differential Mobility Spectrometry

Solución Cuantitativa LC-MS para el Análisis Dirigido de Medios de Cultivo Celular

Enhanced sensitivity for cell culture media analysis (CCMA)

A Comprehensive and Rapid Method for Quantifying Nitrosamine Compounds - Using the SCIEX QTRAP® 6500+ LC-MS/MS System

Quantitative and Qualitative Analysis of Cell Culture Medium Using SWATH® Acquisition

Amlodapine Bioanalysis v10.docx

mAb Oxidation Analysis using X500B and Peptide Mapping

Comparing microflow vs analytical flow high-performance liquid chromatography for the analysis of pesticides

Rapid and Sensitive Detection of 8 Organic Explosives in Soil

Microsoft Word - A Robust and Generic Method for Quantification of Monoclonal Antibody Therapeutics in Biological Matrices_FINA

Metabolite Identification of Payload Species of Antibody Drug Conjugates with Noncleavable Linkers

Profiling of Hop-Derived Bitter Compounds in Beer Using LC-MS/MS

Analysis of the Massachusetts Cannabis Pesticides List Using the SCIEX QTRAP® 6500+ System

LC-MS/MS Method for the Quantification of Budesonide in Human Plasma

Identification and quantitation_X500R QTOF SCIEX OS_food_SCIEX_RUO-MKT-02-3760-A.docx

Emerging food_QTRAP 6500+_PFFA food and food packaging_SCIEX_RUO-MKT-02-2755-A.docx

Análisis de Potencia en Productos de Cáñamo y Cannabis Utilizando un Enfoque Combinado de Dilución única LC-UV-MS / MS

Rapid, Sensitive, Quantitation method for Chloramphenicol in Meat using SCIEX Triple Quad 3500 LC-MS/MS System

Identification and quantitation_X500R QTOF SCIEX OS_food_SCIEX_RUO-MKT-02-3760-A.docx

Comprehensive Characterization of a site-specific antibody-drug conjugate (ADC) by subunit and peptide mapping analysis

Detección de Impurezas de Anticuerpos Intactos en SCIEX X500B

Achieving California Pesticide Regulations in Cannabis Using Optimized APCI and ESI Techniques

Analysis of Streptomycin and its Metabolite in Milk Using the SCIEX Triple Quad 3500 System

Microsoft Word - SCIEX Success Programs Listing v5.docx

Emerging food_QTRAP 6500+_sodium fluoroacetate_SCIEX_RUO-MKT-02-2756-A.docx

Routine Workflow for Comparability Assessment of Protein Biopharmaceuticals

Characterization of 2-AB Labelled Released N-linked Glycans Using the X500B QTOF System

Forensic identification and quantification workflows delivered on QTOF and SCIEX OS software

Increased Throughput for the Characterization of Bispecific Antibodies on Subunit Level using SelexION® Differential Mobility Separation Technology

Rapid Determination of 36 Anti-infective Drugs in Cosmetics by LC-MS-MS

The Application Solution for Determination of 19 Organic Acids by LC-MS-MS Method

Identification and Quantitation of Poisonous Alkaloids in Blood by SCIEX QTRAP

Determination of 6 Catecholamines in Human Plasma Samples by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination of Nitrofuran Metabolites in Animal-derived Food

To Develop Quantitative Analysis Method of Intact Insulin Lispro By SCIEX Triple Quad 7500 System (ZH)

Quantification of Dopamine, Epinephrine, Norepinephrine in Human Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

SCIEX LC-MS-MS Application Technology on Origin Identification of Dairy Products based on Alpha-lactalbumin and Beta-lactoglobulin

A Rapid Screening and Quantitative LC-MS/MS Method of 11 Lipophilic Marine Toxins in Seafood Using SCIEX Triple Quad™ 4500 LC-MS/MS system

Determination of 4 nitrophenol compounds on SCIEX Triple QuadTM 4500 system

Determination of Protein Sequence Mutation and Complex Post Translation Modification on the X500B QTOF System

Determination of Aflatoxins B and G in Grain

应用X500B QTOF系统建立大鼠血浆中siRNA的定量分析方法

Characterization of an antibody-drug-conjugate (ADC) using electron activated dissociation (EAD)

SCIEX Triple Quad™ 6500+系统用于血浆中曲妥珠单抗含量的分析

LC-MS-MS Method for Determination of 523 Pesticide Residues in Traditional Chinese Medicine

Rapid Characterization of the Cow Milk and Human Breast Milk Lipidome using High Resolution Mass Spectrometry X500R System

The Solution of Analysis 13 Nitrosamines in Drinking Water by LC-MS-MS

Determination of Six Antipsychotic Drugs in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

A Rapid Screening and Quantitative LC-MS-MS Method of 14 Sulfonylurea Herbicides Residues in Water by Direct Injection using Triple Quad 3500

Determination of beta-Amyloid Peptide in Human Cerebrospinal Fluid

Targeted Analysis of Eicosanoid in Plasma by LC-MS-MS

Establish a rapid and efficient method for the determination of nitrosamines in cosmetics and personal care products

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

Quantification of 74 Prohibited Hormones in Cosmetics Using LC-MS-MS System

Application of LC-MS/MS in Chinese Pharmacopoeia

Determination of Liposoluble Vitamins in Micro Blood Samples by SCIEX Liquid Chromatography Tandem Mass Spectrometry

Simultaneous determination of 16 sunscreens in Sunblock Cosmetics by Triple Quad 3500

A New Method for Screening, Identification and Quantitation of Fentanyl and its Derivatives by SWATH of X500R

Determination of Sulfonamide Residues in Chicken

Determination of Malachite Green and Crystal Violet Residues in Fish

The Application Solution for Determination of Minoxidil and Other 6 Kinds of Components in Cosmetics by LC-MS-MS Method

Confirmation of Contaminants in Water Using SCIEX Triple Quad 5500plus QTRAP Ready

The Determination of Zearalenone in Traditional Chinese Medicines using LC-MS/MS

LC-MS/MS Method for Rapid Determination of 30 Forbidden Pesticides In Traditional Chinese Medicine

The Determination of Aflatoxins in Traditional Chinese Medicines using LC-MS/MS

SCIEX Triple Quad™ 4500系统快速检测利福平和利福喷丁中两 种亚硝胺类杂质

Improved LC-MRM Quantification Sensitivity for Powder for Inhalation of the Cholinergic Antagonist Family

Determination of 74 Pesticides and metabolites in Soil By LC-MS-MS

Determination 29 β-Agonists in Animal Derived Food by LC-MSMS Method (ZH)

Determination of Beta-agonist Residues in Meat

Application of the QTRAP system in the screening of extractable substance of packaging materials

Determination of 23 Phthalate Esters in Drinking Water By LC-MS-MS

Determination of Quinolone Residues in Animal-derived Food

Determination of Five Antibiotics and their Metabolites in Serum by SCIEX LC-MS/MS

Determination of Genotoxic Impurities Methyl Methanesulfonate and Ethyl Methanesulfonate on SCIEX Triple QuadTM 4500 system

Application in Screening of Packaging Material Extracts Based on X500R QTOF High Resolution Mass Spectrometry

Determination of 23 Phthalate Esters in Cosmetics By LC-MS-MS

A Rapid Screening and Quantitative LC-MS/MS Method of 247 PPCPs and Pesticide Residues in Water by Large Volume Injection

Metabolomic Approach for the Authentication of Berry Fruit Juice by TripleTOF 5600+

Determination of roxarsone in animal feeds using solid-phase extraction coupled with high performance liquid chromatography-tandem mass spectrometry

Determination of Malachite Green and Crystal Violet Residues in Fish

Determination 57 Antihypertensive and Hypoglycemic and Lipid-Lowering Drugs in Blood and Urine by LC-QTOF Method

CESI-MS/MS和LC-MS/MS技术对生脉注射液成分的分析

Determination of alkylphenol ethoxylates in textile and coatings by LC-MSMS Method

应用LC-MS/MS快速分析化妆品中10种α-羟基酸

SCIEX Tandem Mass Spectrometry Method for Quantification of Chondroitin Sulfate and Dermatan Sulfate by Methanolysis Derivatization

Determination of OPEs in human plasma with LC-MS/MS system

Quantification of Arginine, Homoarginine, Asymmetrical Dimethylarginine and Symmetric Dimethylarginine in Human Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Simultaneous Determination of Linezolid, Voriconazole, Imatinib, Dasatinib, Nilotinib, Dabigatran Etexilate and Rivaroxaban in Plasma by SCIEX LC-MS/MS

High-sensitivity detection of forensic drug panel in human whole blood (ZH)

A Rapid Screening and Quantitative LC-MS-MS Method of 189 Veterinary Drug Residues in Animal Food by High Resolution Mass Spectrometry X500R

The Application of TripleTOF 5600 System for Identification of Chemical Components in Polygonum Cuspidatum

Determination of 13 Bile Acids in Serum by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Identification of Extractable and Leachable in Single Use Packaging of Drug on the X500 QTOF System

处理前后的饮用水筛查的两种非靶向流程

LC-MS/MS法快速测定动物源食品中205种兽药的完整解决方案

The Application of Analysis 13 Haloamides in Drinking Water by LC-MS-MS

Identification of Carbamate Pesticide Metabolites in Soil with LightSight Software Combined with QTRAP System

Rapid Determination of 8 Macrolides Antibiotics in Cosmetics

The solution for amantadine, rimantadine and ribavirin residues in animal-derived foods by LC-MS /MS

Determination of Aflatoxins B&G in Grain

LC-MS-MS Method for Rapid Determination of 30 Forbidden Pesticides In Traditional Chinese Medicine

The Application Solution for Determination of Fluconazole and other 8 Kinds of Components in Cosmetics by LC-MS-MS Method

Composition Identification of Leachable from Polypropylene Infusion Bottle by X500R High Resolution Mass Spectrometry

Determination of Tetracycline Antibiotic Residues in Animal-derived Food

Analysis of Six Organotin Compounds in Food package Material by LC-MS-MS

Quickly identification of phase II metabolites in plasma after oral Compound Traditional Chinese Medicine by SCIEX TripleTOF system software

A Rapid Screening and Quantification Method of Forbidden and Restricted Pesticides in Traditional Chinese Medicine by LC-MS-MS

Simultaneous Determination of 14 Paralytic Shellfish Toxins in Seafood using LC-MS-MS

Determination of Nitrofuran Metabolites in Animal-derived Food

Detection of 8 Antioxidant Residues in Food Package by Triple Quad 4500

Determination of 20 Steroid Hormones in Human Serum Samples by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Analysis 106 Compounds in Cell Supernatant by Using LC-MS-MS

Determination of Caspofungin Posaconazole Voriconazole N-Oxide and Voriconazole in Plasma by SCIEX Liquid Chromatography-Tandem Mass Spectrometry

Determination Trace Residues of Whey Protein in Lactose by LC-MS-MS

Identification and Quantitation of Fentanyl and Analogues in One Injection by SCIEX QTRAP

Rapid and Sensitive Analysis of Drugs of Abuse by SCIEX Triple Quad 3500 LCMS System

Determination of Chloramphenicol Thiamphenicol and Florfenicol Residues in Fish

High Resolution Mass Spectrometry X500R QTOF System on The Routine Monitoring of Cosmetics Illegal Drug

Simultaneous Determination of 7 Kinds of Local Anesthetics in Cosmetics by High Performance Liquid Chromatography-Mass Spectrometry (ZH)

The Solution of Methamphetamine Detection

Simultaneous quantitative analysis of metronidazole and chloramphenicol in chicken by SCIEX LC MS-MS

Detection of 13 Haloamides in Drinking Water by Triple Quad TM 5500

A Rapid Screening and Quantitative LC-MS/MS Method of 40 Illegally added drugs in health-care food using SCIEX Triple Quad TM 3500 LC-MS/MS system

LC-MS-MS Method for Rapid Determination of Volatile Aldehydes in Cells

Determination of Quinolone Residues in Animal-derived Food