Knowledge Base Article


Knowledge Base is your tool to finding answers about common questions. Browse all Knowledge Base articles below. 

Adjust the regional language in LibraryView™ software to correct the SCIEX L:icense Notification screen

This article describes how to change the regional language settings within LibraryView™ and SCIEX OS Software. This prevents the license notification screen from popping up.

03/15/2024    SCIEX OS

How can I change an audit map's settings in Analyst® software?

To check a project and see how an audit map is applied or to change the settings for an audit map for a particular project in Analyst® software, navigate to the Audit Trail Manager. Select the Audit Trail Manager option under the View menu and the Audit Trail Manager window will open.

03/15/2024    Software

MultiQuant™ MD software error: Missing active project folder

Description on how an Analyst error causes MultiQuant™ companion software within Analyst® software to not function correctly.

Creating a batch template in Analyst® software

When submitting a batch in Analyst® software, it's convenient to use a template that be opened and modified to submit future batches without having to reenter sample, internal standard or known concentration information. To do create a batch template, open Analyst® software, activate a hardware profile, and then select Build Acquisition Batch in the vertical Navigation Bar.

03/15/2024    Software

How is the FDR calculated in the peptide-spectrum matching step in the BioPharmaView™ software?

This article describes how the false discovery rate (FDR) is calculated in BiopharmaView™ and BPV Flex software.

03/15/2024    Academia Omics | Pharma CRO

How to import a batch template into Analyst software

Batch templates allow users to save time by applying information from a previous batch to a current batch of samples for queue submission in Analyst® software. Users will need to update any sample information that has changed prior to submitting the new sample information to the queue.

03/15/2024    Software

Canned Calculation for SANTE Guideline 12682_2019 - C18 Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C18. The guidance section deals with the requirements to perform calibration by interpolation.

02/28/2024    SCIEX OS

How can I enable the MSServiceLog Script in Analyst® software to record readbacks from a mass spectrometer?

By default, readbacks from a mass spectrometer are recorded in the MS Service log file. Use the MSServiceLog script to turn off the recording of the readbacks or to start recording the readbacks from the instrument in the MS Service log file. The MSServiceLog script is only applicable to the SCIEX 3500, 4500, 5500, 5500+, 6500, and 6500+ systems. The MSServiceLog script can be used without an active hardware profile but any changes made to the MS Service log settings take effect only after the hardware profile is reactivated.

Canned Calculation for ICH Guideline M10 – 3.2.2 Specificity Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.2. The guidance requires that it is demonstrated that no significant response attributable to interfering components compared to the analyte or IS response in the blank and double blank samples, respectively, is observed. These calculations were created to provide a ready-made solution for determining which samples will need to be re-injected in pesticide reports.

How to export the Sample type in automatic reports generated by ChemoView™

The automatic reports that are generated by ChemoView™ are not capable of using all the tags that are also used by Analyst® software. The tag which allows to export the Sample type does not work. The procedure described in this article explains how to work around this issue.

Canned Calculation for ICH Guideline M10 – 3.3.2 Quality Control Check Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.3.2. The guidance requires that at least 2/3 of the total QCs and at least 50% at each concentration level should be within ±15% of the nominal values and that the revised calibration range should cover at least 3 QC concentration levels (low, medium and high). These calculations were created to provide a ready-made solution for flagging outliers.

02/07/2024   

Canned Calculation for ICH Guideline M10 – 3.2.6 Carry Over Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.6. The guidance requires that carry-over in the blank samples following the highest calibration standard should not be greater than 20% of the analyte response at the LLOQ and 5% of the response for the IS. These calculations were created to provide a ready-made solution for flagging in case of carry-over above the limit is detected.

02/07/2024   

How to perform Positive charging test using Sciex OS® on 7500 instruments

How to perform Positive charging test using Sciex OS® on 7500 instruments

02/02/2024    Mass Spectrometers

How can I avoid the following error message in Analyst® software: “Failed 5% manual integration rule. Reverting back to original peak area.”

If the percentage of the Percent Rule in the Peak Review Default Options has been changed, this can lead to an error message when a manual integration is executed.

01/31/2024   

Canned Calculation for SANTE Guideline 12682_2019-D2 bis - Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 – D2 bis. The guidance requires that analyte retention times in the extracted pesticide samples should fit to that from the calibration standards. These calculations were created to provide a ready-made solution for flagging problematic samples/components.

01/31/2024   

How to perform Positive charging test using Sciex OS® on Blueline instruments

How to perform Positive charging test using Sciex OS® on Blueline instruments

01/31/2024    Mass Spectrometers

Create fast optimization acquisition methods for Q0D mapping in SCIEX OS software

With the Q0D mapping calculation sheet you can easily create acquisition methods for the optimization of Q0D values on column with matrix.

01/31/2024    SCIEX OS

Canned Calculation for ICH Guideline M10 – 3.2.4/3.3.2 Calibration Standard Accuracy Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.4/3.3.2. The guidance requires that the accuracy of the back-calculated concentrations of each calibration standard should be within ±20% of the nominal concentration at the LLOQ and within ±15% at all the other levels. At least 75% of the calibration standards with a minimum of 6 calibration standard levels should meet the above criteria. These calculations were created to provide a ready-made solution for flagging problematic samples/components.

01/30/2024    Pharma CRO | SCIEX OS

Canned Calculation for ICH Guideline M10 – 3.2.1 Selectivity Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in ICH guideline M10 – 3.2.1. The guidance requires that it is demonstrated that no significant response attributable to interfering components is observed at the retention time(s) of the analyte or the IS in the blank samples. These calculations were created to provide a ready-made solution for flagging problematic samples/components.

01/30/2024    Pharma CRO | SCIEX OS

Canned Calculation for SANTE Guideline 12830 2020 – Residual Plot Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in SANTE Guideline 12830 2020 – Residual Plot. The guidance recommends that the suitability of the chosen calibration function is demonstrated with a residual plot. These calculations were created to provide a ready-made solution for the visual inspection of the residuals and can be combined with a specific report.

01/30/2024    SCIEX OS

Canned Calculation for SANTE Guideline 12682_2019 - C15 Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C15. The guidance requires that without a bracketing calibration the determination system has been shown to be free from significant drift, e.g. by monitoring the response of an internal standard. These calculations were created to provide a ready-made solution for evaluating a possible drift in the internal standard response.

01/30/2024    SCIEX OS

Generating a Service Package in Sciex OS Software

To generate a service package in Sciex OS software that contains the event logs, select Configuration, About, and Generate a Support Package.

01/15/2024    SCIEX OS

How to create a hardware profile in "read only" mode in Analyst®

In Analyst®, if you use hardware profiles with AAO system it is recomended to put the hardware profile in "read only" mode to prevent file corruption issue.

01/12/2024    Analyst Software

Where to find Signal-to-Noise in SCIEX OS Explore mode

This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.

12/08/2023   

Where to find Signal-to-Noise in SCIEX OS Explore mode

This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.

12/08/2023   

Where to find Signal-to-Noise in SCIEX OS Explore mode

This article explains how you can manually evaluate the Signal-to-Noise within a chromatogram in the SCIEX OS Explore mode.

12/08/2023   

Signal Noise in Sciex OS Sofware - Analytics (Sciex OS 2.0 or Higher)

This article shows how to select and apply signal to noise algorithms and how to use them

12/07/2023   

Cleaning of SelexION™ Cell and Electrodes

This article describes different levels of cleaning the SelexION™ cell and electrodes

12/07/2023   

How to Avoid Corona Discharge in Electrospray Ionization (ESI)

This article describes measures to avoid corona discharge

12/07/2023   

How can I Change the Font Size of Text Fields in the Report Templates (Analyst®, MultiQuant™, SCIEX OS Software)?

This article shows how to change the font size of text elements in Reporter templates

12/07/2023   

How to Add Additional Amino Acids into Molecule Profiler Custom Elements List

This article demonstrates how to add additional amino acids into the custom elements list of Molecule Profiler

12/07/2023   

Finding the Number of Points Across a Peak in Sciex OS Software

This article shows the possibilities to determine the amount of data points across a peak

12/06/2023   

Create fast optimization acquisition methods for Q0D mapping in SCIEX OS software

With the Q0D mapping calculation sheet you can easily create acquisition methods for the optimization of Q0D values on column with matrix.

12/06/2023   

SelexION® and Selexion®+ - How to Avoid Discharge Error

This article lists reasons for discharge error on SelexION® and Selexion®+ and how to avoid those

12/06/2023   

Shimadzu LC-40 systems troubleshooting tips and tricks

The table shows the most common symptoms encountered for Shimadzu LC-40 systems and details possible causes with the appropriate corrective action. This HPLC system is commonly used with SCIEX mass spectrometers. Design changes in this model vs older Shimadzu models may require a different approach to troubleshooting your LC-MS system.

11/16/2023   

How to generate reports in CSV format with SCIEX OS if no comma-separated report style is visible

If no comma-separated report style is visible, you must change the extension of the TXT file to CSV when saving the file.

11/14/2023    SCIEX OS

How To Perform A Master-Reset For PA800 Series

32 Karat Software and Pa800 Plus transport problems can occur due to faulty EEPROM values. These corrupt EEPROM values can be fixed with a Master-Reset

10/30/2023   

Replacing the electrode in the SCIEX ion source that is compatible with the Eksigent microLC 200 LC system

A YouTube video demonstrates how to replace the electrode in the SCIEX ion source that is compatible with an Eksigent microLC 200 system connected to a SCIEX mass spectrometer and operated by the Analyst® software.

10/20/2023    QTRAP Systems | Triple Quad Systems

Inputting known concentrations of analytes into a batch in SCIEX OS software

In SCIEX OS software it is possible to input known concentrations of analytes and internal standards for Quality Control and Standard sample types. This prevents having to add the values directly to the results table and saves time when analyzing data.

10/20/2023    SCIEX OS

Name conflict error when creating a new quantitation method in MultiQuant™ software

The error message, "The specified name conflicts with an analyte in another period/experiment" appears when making a new quantitation method in MultiQuant™ software. This error is the result of one or more analyte names in the current experiment being identical to one of the analyte names(s) in another experiment within the same processing method.

10/20/2023    MultiQuant Software

Molecule Profiler software 1.3 supports the entire sequence of an antibody drug conjugate (ADC) in a dedicated workflow

Molecule Profiler software version 1.3 supports a dedicated workflow for antibody drug conjugates (ADCs). The entire antibody sequence can be copied into the software for processing.

How To Report Out Regression Types in Reporter Template Suite 3.2

To report out the regression type used in a curve fit, a combination of IF, ELSEIF, and ELSE tags are required in the report template in Reporter Template Suite 3.2.

How does increasing column temperature affect LC methods?

Increasing the column temperature can affect liquid chromatography (LC) parameters positively by decreasing column pressure, reducing retention times, and lowering the overall analysis time. Fluctuation in column temperature can result in unstable retention times and peak shapes.

10/20/2023    Mass Spectrometers | Software

Processing parameters for an antibody drug conjugate (ADC) Workflow in Molecule Profiler software 1.3

The antibody drug conjugate (ADC) workflow in Molecular Profiler software 1.3 helps to identify and further characterize cytotoxic drugs, their breakdown products, and the linker connected to the entire antibody sequence. This article describes how to set up the processing parameters for the ADC workflow.

Optimization Report (XPS File) in SCIEX OS Software Does Not Display Graphs

After completing a multiple reaction monitoring (MRM) infusion in SCIEX OS software, the optimization report (.xps file) does not have any graphs displayed even though the graphs appeared in the software after the optimization was completed. This is due to a Windows update (update for Microsoft Windows KB5020866) that restricts .xps files.

10/20/2023    SCIEX OS

What Are the Different Data File Types in Analyst® and SCIEX OS Software?

In the data sub-project within a project folder in Analyst® or SCIEX OS Software, there can be a multitude of file types associated with one set of raw data. The file types and the software they are associated with are listed in this article.

10/20/2023    SCIEX OS | Analyst Software

How can I quantify efficiency of my extraction method in SCIEX OS software?

Extraction efficiency is the percentage of analyte recovered through the extraction process, from the start of extraction to the final step of sample preparation prior to LC/MS analysis. This article explains how to quantify the extraction efficiency in SCIEX OS software.

10/19/2023    SCIEX OS | Mass Spectrometers

What are the suggested time intervals when using a diverter valve?

Efficient use of diverter valve will keep the mass spectrometer source and ion optics from unnecessary and excessive contamination. This article provides guidance on how to set an appropriate time range for use of a diverter valve during an acquisition method.

How is low resolution set up and tuned in Analyst® software?

To set up low resolution for mass calibration in Analyst® software during instrument optimization, users can choose unit and low resolution and then set it up the parameters accordingly under the Tuning Options screen.

10/19/2023   

How to Reduce the Column Pressure during Liquid Chromatography?

When a new liquid chromatography (LC) method is developed, the pressure might be too high and close to the maximum pressure allowed by the hardware. It is important to address this issue before validating the method.

10/19/2023    Mass Spectrometers

Is sensitivity lowered for MRM acquisition methods with polarity switching for a SCIEX 5500 system and other instruments?

If user adds polarity switching to a MRM acquisition method that includes both negative and positive experiments, it is possible in theory to have a different signal intensity (usually lower). But having the appropriate settling time in the MRM method will prevent this in most cases.

10/19/2023    QTRAP Systems | Triple Quad Systems

What is matrix effect and how is it quantified?

The loss of analyte signal due to presence of matrix in sample is called matrix effect in analytical chemistry. Here the quantitation of matrix effect is also explained.

10/19/2023    Mass Spectrometers | Software

How to Adjust LC Flow Rates after Changing a Column’s Inner Diameter (ID)

If a user is following an existing liquid chromatography (LC) method but is using a column with an inner diameter (ID) that differs from the original method, how should the LC parameters change?

10/19/2023   

How to check if the CAD gas is properly working in Analyst® software

The collision associated dissociation (CAD) gas is an inert gas that breaks parent compound ions into smaller fragments, making it an important component of multiple reaction monitoring (MRM) methods in Analyst® software. It is introduced by diffusing a small stream of nitrogen through a small orifice into the Q2 of a mass spectrometer. On rare occasions, this orifice might become blocked or out of calibration.

10/18/2023   

Why do extracted samples and quality controls have lower signal compared to neat standards?

When a sample or a spiked quality control is extracted, the signal is usually lower than that of the corresponding standard made in pure solvents.

Batch submission error in Analyst® software: Exceeding the maximum number of waiting samples

When submitting a batch in Analyst® software, an error message appears: You are exceeding the maximum number of waiting samples configured in the queue options. The solution is to increase the maximum number of waiting samples in the Queue Options under the Settings menu in Configure mode.

10/18/2023   

What is the best way to flush a liquid chromatography system to remove contamination?

Contamination of a liquid chromatography (LC) system usually requires flushing the system with an organic solvent to remove unwanted background. Here an effective way to flush the entire LC system is discussed.

10/18/2023    Mass Spectrometers

Which mass spectrometers and ion sources are supported by SCIEX OS software?

If a new flow rate is desired for a LC/MS experiment, a different ion source may be needed for your SCIEX mass spectrometer. Included here is a list of current mass spectrometers and ion sources that are supported by the most recently released of SCIEX OS software, version 3.3.

10/18/2023    SCIEX OS | Mass Spectrometers

Calibration peak list is missing during instrument optimization in Analyst® software

During instrument tuning and calibration in Analyst® software, the calibration peak list can be obtained by right clicking on the final spectrum and selecting the List Data option. This will open a new pane that contains the calibration peak list. In this tab, the exact expected masses of the calibration components (e.g., PPG positive) are listed.

10/18/2023    Analyst Software

Where can I read the vacuum gauge pressure for a SCIEX mass spectrometer in Analyst® software?

For current vacuum gauge pressure readings, double click on mass spectrometer icon at the bottom right corner of Analyst® software to open the MassSpec Detailed Status window. Under the Vacuum System Status section, the real-time readout for the vacuum gauge pressure is visible.

10/18/2023   

Understanding the ion source parameters in Analyst® and SCIEX OS software: GS1, GS2, TEM and CUR

For mass spectrometry acquisition methods in Analyst® or SCIEX OS software, values will need to be set for source parameters that influence the degree of ionization in an electrospray ionization (ESI) source. These values include GS1, GS2, TEM and CUR gas.

10/17/2023   

What Curtain Gas Settings Should Be Used on SCIEX 3200, 4000 and 5000 Series Systems?

The curtain gas (CUR) is an important parameter that protects SCIEX mass spectrometers from contamination. The proper amount of curtain gas depends on the LC flow introduced into ion source and the model of SCIEX mass spectrometer used. This article explains the CUR value used for SCIEX 3200, 4000 and 5000 series systems.

10/17/2023   

What Curtain Gas (CUR) Settings Should Be Used on SCIEX 3500, 4500 and 5500 Systems?

The curtain gas (CUR) is an important parameter that protects the mass spectrometer from contamination. However, the proper amount of curtain gas depends on the LC flow introduced into ion source and the model of SCIEX mass spectrometer used. This article provides the CUR settings for the SCIEX 3500, 4500 and 5500 (5500+) series systems.

10/17/2023   

How to change source, gas and other default acquisition method parameters in Analyst® software?

When a new method is opened in Analyst® software, the source and gas parameters, including the declustering potential (DP), the collision energy (CE) and the collision cell exit potential (CXP), are populated based on the software's default parameters. Automatic compound optimization method also uses these default values.

10/14/2023    Analyst Software

Is PeakView® software required when processing data in the OneOmics™ suite 3.4?

PeakView® software 2.2  is not required when processing data in the OneOmics™ suite 3.4, but it is required to upload data to the OneOmics suite using the CloudConnect app.

Common installation issues when upgrading SCIEX OS software

Some of the most common issues encountered while upgrading the SCIEX OS software and how to prevent them are listed here. Please consult the SCIEX OS software installation guide found in the installer package for step-by-step instructions for correctly upgrading the software.

10/14/2023    SCIEX OS

Restoring Missing Toolbars and Menus in Analyst® Software

If the toolbars in Analyst® software disappear, leaving a blank, grey area. they can be restored using the command ALT T.

10/13/2023    Analyst Software

Common Installation Errors for SCIEX OS Software

This article describes the common installation issues that occur when installing SCIEX OS software for the first time. To install SCIEX OS software successfully, the Installation Guide should be consulted and each section should be read prior to installing the software.

10/13/2023    SCIEX OS

Recommendations for lower and upper temperatures for an Exion 2.0 method in Analyst® software

When working with an acquisition method that uses an Exion 2.0 LC system in Analyst® software, the lower and upper temperature settings should be set slightly higher or slightly lower, respectively, than the safety limits to prevent column oven errors.

10/13/2023    Software

Can two analytes have the same transitions in an MRM method in SCIEX OS software?

Occasionally two different analytes in the same MRM method in SCIEX OS software may have identical Q1 and Q3 masses for their respective MRM transitions. The question is if this could cause problem in quantitation and what should the user do to avoid errors.

10/13/2023    SCIEX OS

Can a different user log into Analyst® software set to integrated or single user mode?

No, opening the Analyst® software as a different user when the security configuration is set to integrated mode or single user mode is not supported.

10/13/2023    Software

How To Change the Number of Available Rows in the Batch Workspace in SCIEX OS Software

In SCIEX OS software, it is possible to change the number of available rows in the batch. To do this, select the View button in the top right of the batch workspace.

10/13/2023    SCIEX OS

Calculating the MS2 Score in the BioPharmaView™ Software for Confident Selection of Peptides for Quantification

In BioPharmaView™ software, the MS2 score evaluates the quality of a match between MS/MS peaks and a set of theoretical fragments. The MS2 score is based on the probability of the MS/MS peaks matching the set of theoretical fragments of the molecule by chance. The score is calculated automatically by the software.

How To Utilize the Quick Batch Option in SCIEX OS Software

A new option for creating batches quickly was introduced in SCIEX OS software version 3.1.6 and is called Quick Batch. To utilize Quick Batch, an icon in the upper right corner of the Batch screen will need to be selected.

10/13/2023    SCIEX OS

Error when Opening Analyst® Software: Error 1067

After installing Analyst® software 1.7 alone or with Hotfix 1, attempting to open the software results in an error: Error 1067: The process terminated unexpectedly.

10/13/2023    Analyst Software

The Metabolomics Workflow in OneOmics™ Suite 3.4 Offers a New NIST Library Search

The OneOmics™ suite 3.4 offers a new feature in its metabolomics workflow where the NIST library can be selected as a library option in the Merge workflow.

10/13/2023    Academia Omics | Pharma CRO | Software

How To Create Personalized Toolbars in Analyst® Software

To create custom toolbars In Analyst® software and have more personalized access to shortcuts and icons, select the View menu and click on Toolbars. Selecting the New or Customize options will allow for new new toolbars to be created or for customized icons to be added to the toolbars.

10/13/2023    Analyst Software

Reporter 3.2 Error In Analyst® Software: Unable To Cast COM Object

When attempting to generate a report in Analyst® software with Reporter 3.2, an error appears immediately after clicking on create report: Unable to cast COM objectnof type System_ComObject' to interface.

10/13/2023    Analyst Software

Accessing ProteinPilot™ Software Searching in the OneOmics™ Suite

To log into the SCIEX Cloud workspace and access the ProteinPilot™ software searching features with a CloudConnect license, follow the instructions below.

Can SCIEX OS software be used for acquisition on all SCIEX instruments?

To determine if a particular version of SCIEX OS software supports acquisition on a SCIEX instrument, please consult the installation guide for that version of the software. SCIEX OS software does not support acquisition on legacy instruments such as the API™ 3200 and 4000 systems.

10/13/2023    SCIEX OS

How to set Root Directory in SCIEX OS Software?

Per default, the root directory of SCIEX OS Software is set to C:\SCIEX OS Data. The Managment part of the software provides the possibility to define another root directory path and folder name.

10/13/2023   

Performing a ProteinPilot software search with the Mascot server enabled

ProteinPilot™ software 5.0.1 can perform searches using the Mascot server. To use the Mascot server, a license is required, and this must be purchased from Matrix Science. Step-by-step instructions are provided in this article for setting up a search with ProteinPilot software 5.0.1 and Mascot version 2.6 or higher.

Considerations when Creating a Library-Free Proteomics Experiment without the OneOmics™ Suite

Library-free proteomics experiments require highly reproducible sample-handling protocols and data analysis and can be done directly in DIA-NN software without any other SCIEX software or ion libraries. 

10/13/2023    Academia Omics | QTOF Systems

Where are print templates stored in SCIEX OS?

A new print template feature appears in SCIEX OS software starting in version 3.1 that allows for batch, queue, and processing methods to be printed for record-keeping purposes. The templates can be accessed from the Configuration tile by selecting the Print Templates tab. Users can customize templates and apply them to specific projects.

10/11/2023   

How can I set up contact closure in SCIEX OS software for my SCIEX instrument?

To set up contact closure for a SCIEX mass spectrometer to communicate with an external LC system, the contact closure check box must be selected in the instrument's hardware profile in SCIEX OS software. SCIEX OS software 3.1.6 supports many of the same legacy instruments that were controlled by Analyst® software even if contact closure is required for a third-party vendor LC system.

10/09/2023    SCIEX OS

Removing an ESI probe to change the capillary on a SCIEX mass spectrometer

Capillaries can get blocked and will need to be replaced from time to time to maintain high quality spray from an electrospray ionization (ESI) probe. This article provides a link to a YouTube video that shows how to remove an ESI probe to change the capillary on a SCIEX mass spectrometer.

10/09/2023    Mass Spectrometers

Upgrading the Biologics Explorer software

General steps for the upgrade process for the Biologics Explorer (BE) software are described in the release notes. Versions of SCIEX OS software 3.1.5 and greater, have an embedded BE software tile. For those versions of SCIEX OS software containing the BE tile, the SCIEX OS software must first be closed, and all SCIEX OS services stopped before proceeding with the BE software upgrade.

10/09/2023    Academia Omics | Pharma CRO | Software

Will my old workflow templates or data be lost when upgrading Biologics Explorer software?

The Biologics Explorer software will automatically save all workflow templates and data from previously installed versions.

10/09/2023    Academia Omics | Pharma CRO | Software

Where can I find general security recommendations for my PC running SCIEX software?

The security guidance provided in the link in this article contains supplemental instructions for protecting acquisition and processing computers that are running SCIEX software. This guidance is intended to supplement rather than replace current IT policies, requirements and practices.

10/09/2023   

Adding MS/MS information to the MRMHR processing method's Components tab in SCIEX OS software

To add the MS/MS information to a MRMHR processing method in SCIEX OS software, a compound name, a unique name for the fragment ion, and the fragment mass information are required in the table under the Components tab.

10/09/2023    SCIEX OS

What MRM modes are available on SCIEX TripleQuad and QTRAP systems?

There are four different multiple reaction monitoring (MRM) modes that can be acquired using SCIEX TripleQuad or QTRAP systems with SCIEX OS software: MRM, scheduled MRM, scout triggered MRM RT mode, and scout triggered MRM group mode.

10/09/2023   

How to upgrade your SCIEX mass spectrometer's firmware after upgrading the SCIEX OS software

After upgrading SCIEX OS software on an acquisition PC, the instrument firmware also needs to be upgraded. To do this, follow the instructions in the SCIEX OS software installation guide in the sections MS FW Updater Utility and Mass Spectrometer Firmware Versions.

10/08/2023    SCIEX OS

Where is the file for the hardware profile used in Analyst® or Analyst TF software located?

The file corresponding to the hardware profile used in a Analyst® or Analyst TF software is located in the API Instrument project in the Analyst Data folder.

10/06/2023    Analyst Software

How To Ramp Parameters in SCIEX OS Software during Compound Optimization

When using SCIEX OS software to optimize compounds that are being infused using a syringe pump, it is possible to ramp individual compound parameters such as collision energy (CE), entrance potential (EP), and collision cell exit potential (CXP), and Q0 dissociation (Q0D). This process may be preferred to guided MRM optimization in the event that a more manual and controlled optimization is desired.

10/06/2023    SCIEX OS

Where are print templates located in SCIEX OS software?

A new print template feature appears in SCIEX OS software starting in version 3.1 that allows for batch, queue, and processing methods to be printed for record-keeping purposes. The templates can be accessed from the Configuration tile by selecting the Print Templates tab.

10/06/2023   

Impermissible Symbols for Root Directory Paths and Project Names in SCIEX OS Software

There are some symbols which cannot be used when naming a root directory path or a project in SCIEX OS software. They are detailed in this article.

10/06/2023    SCIEX OS

What version of SCIEX OS software includes a tile for Biologics Explorer software?

A tile for Biologics Explorer (BE) software appears in SCIEX OS versions 3.1.5 and higher. The BE software can be launched from this tile, but the BE software needs to be installed from a separate installer as described in this article.

10/06/2023    Academia Omics | Pharma CRO | SCIEX OS

Enabling ChemSpider funtionality in SCIEX OS software

To enable the ChemSpider feature within SCIEX OS software, the ChemSpider add-on license must be added to the SCIEX OS software program files and the Formula Finder feature must be enabled in the processing method.

How to report Dell PC hardware issues for computers not under service contract

For Dell computers experiencing hardware issues that were purchased from SCIEX but are no longer under a service contract, users can reach out directly to Dell for support using the link provided in this article.

10/06/2023   

What is the maximum project size in the SCIEX OS Data folder that still permits software efficiency?

There is no limit on the number of projects created in the SCIEX OS Data folder.  Additionally there is no limit to the number of subproject folders under a current project.

10/05/2023   

Proteases such as trypsin and beta galactosidase sold by SCIEX have no certificates of analysis (CoA)

Certificates of analysis (CoA) are available for various reagents; however for proteases such as trypsin and beta galactosidase that are sold by SCIEX, no CoA is available.

10/05/2023    Standards and Reagents

How is the Default Column 'Asymmetry Factor' calculated in SCIEX OS?

Asymmetry Factor: Asymmetry factor is a measurement of how well the peak matches the ideal peak shape. As = b/a where b is the distance from the peak apex to the trailing edge of the peak measured at 10% of peak height and a is the distance from the leading edge of the peak to the peak apex measured at 10% of peak height. If As > 1 : tailing, et si As < 1 : fronting

10/04/2023   

How to reduce matrix effect and increase analyte signal in extracted samples?

Presence of matrix could result in lower analyte signal and reducing matrix effect could potentially increase signal and result in better (lower) limits of detection

09/25/2023   

Error with MPX™ Software 1.2: Unable To Access Autosampler Database

When launching MPX™ software 1.2 on a Windows 7 64-bit operating system, an error appears, "Unable To Access Autosampler Database".

09/22/2023    MPX Software

How to initiate injection counter in Analyst® Software version 1.7.3

How to initiate injection counter in Analyst® Software version 1.7.3

09/22/2023   

What to do if a service package cannot be created in SCIEX OS or Analyst® software?

If a service package cannot be generated in SCIEX OS or Analyst® software, the event logs, installed programs and other important system information can be manually provided for trouble shooting purposes.

09/22/2023   

What are Metric Plot Settings in SCIEX OS software and where are they saved?

Metric Plot Settings allow the user to customize the appearance of the Metric Plot pane.

09/22/2023   

How do I create a new entry in the automatic calibration editor in SCIEX OS software

For the batch calibration of high-resolution instruments within SCIEX OS software the Automatic Calibration Editor can be used. Some "ion reference tables" are pre-installed, but they can be customized, or new tables can be added.

09/22/2023   

Locating the List of Isotopic Amino Acid Symbols in Bio Tool Kit Software

The Bio Tool Kit microapp can be used for peptide sequencing or fragment matching in PeakView™ or SCIEX OS software. The one-letter codes for amino acids are used when entering potential fragment ions. To represent isotope-labeled amino acids, square brackets encompassing the mass shift are used to the right of the one-letter code. In Bio Tool Kit software, the information for all heavy amino acids is stored in the AA Modifications tab in the Mass Calculator.

How to perform a source back out (Pyrolysis) in SCIEX OS software or Analyst® software?

In some circumstances, e.g., infusion of very high concentrations of standards or matrices, the source may be contaminated. Baking out helps to remove the impurities.

09/22/2023   

How to modify ParameterSettings for APCI “Compound Optimization” in Analyst® software?

The automated “Compound Optimization” within Analyst® software takes over the values set in the parameter settings. The values are optimized for infusion flows around 10 µl/min. For APCI, a flow of at least 200 µl/min is needed, which is why the values for the gases and the temperature must be adjusted.

09/22/2023   

How to initiate and activate Auxiliary traces in Analyst® Software version1.7.3

How to initiate and activate Auxiliary traces in Analyst® Software version1.7.3

09/22/2023   

How do I create a Shortcut in SCIEX OS Software and which shortcuts are available?

Overview of available combinations of keystrokes that provides easier access to a command or operation in the SCIEX OS software.

09/22/2023   

Purpose of a Lockfile Alongside a Results Table File in Analyst® Software

In Analyst® Software, when opening a results table, an additional file - the lockfile - appears in the Quantitation Results folder for a particular project. The purpose of the lockfile is to prevent a second user from opening the same results table simultaneously and trying to modify it.

09/22/2023    Analyst Software

Changing the Y-Axis Scale from Relative Intensity Percent in Analyst® Software,

When opening raw data in Analyst® software, the Y-axis label reads Rel Int. % with values from 0-100% instead of showing the true intensity value. In the Appearance Options window, select Other Graph Options. Under Percent Y Axis, change the value under the Chromatogram column from Yes to No to set the Y-axis scale back to intensity.

09/22/2023    Analyst Software

Calculating Mass Properties using a Compound's Formula In Analyst® Software

The mass properties of a compound (e.g., average mass, exact mass, nominal mass) can be calculated from its chemical formula using the calculators found in the Tools menu in Analyst® software.

09/22/2023    Analyst Software

How To Change the Instrument Idle Time In SCIEX OS Software

After a set time (the instrument idle time) has elapsed, the system will go into Standby state – whereby the LC pumps, column oven and some mass spectrometer voltages are turned off. To change the instrument idle time in SCIEX OS software, navigate to the Configuration pane, and select the Queue tab. The instrument idle time can be changed by typing the desired time into the field.

09/22/2023    SCIEX OS

Where is the folder location for LibraryView 1.6 software license file?

This will help the user to access the existing LibraryView (version 1.6) license file, or it could help user to place the recently obtained license file into the correct folder on the computer.

09/21/2023   

ProteinPilot™ software 5.0.3 is needed to view group files from OneOmics™ suite

In order to view group files generated by ProteinPilot™ software from the OneOmics™ suite, users must install ProteinPilot software 5.0.3, a beta version of the software that is not currently available from the SCIEX software downloads page. The link to the installer is provided in this article.

How Do I Work with LC Devices Not Directly Controlled by SCIEX OS Software?

To synchronize signals between a SCIEX mass spectrometer, the SCIEX OS software and LC devices that are not directly controlled by the SCIEX OS software, contact closure can be used.

09/16/2023    Software

DIP Switch Positions when Connecting Agilent LC Systems to SCIEX Mass Spectrometers

When connecting Agilent LC Systems to a SCIEX mass spectrometer, the dual-in line packet (DIP) switches on the Agilent LC systems should be in the down (off) position, except for switches 7 and 8 which must be in the up position for the pump and detector.

09/15/2023    Mass Spectrometers | Software

How to Save Application, System and Security event logs in Windows®10

The Windows event logs often contain crucial data about the performance of SCIEX software. Follow this guidance to save your System, Security and Application event logs so that they can be analyzed by the SCIEX support team.

09/08/2023   

How can I generate a Batch-Import-Template for SCIEX OS to set up my manual LIMS connection?

SCIEX OS can import batch information from a LIMS system if the import file (*.csv/*.txt) follows defined layout rules. To have the proper layout an example batch can be exported from SCIEX OS to be used as a template.

09/07/2023   

Can the New Dry Pump MSR 90 for the 6500+ System Be Installed with Analyst® Software?

The new Dry Pump MSR 90 can only be operated with SCIEX OS software on the 6500+ system. It is not compatible with the Analyst® software for data acquisition.

09/01/2023   

Maintaining the Ion Spray Voltage when Using the Nano OptiFlow® Turbo V Ion Source

In order to maintain the ion spray voltage while operating the nano OptiFlow® Turbo V ion source, one option is to leave the mass spectrometer in Standby mode (LC pumps are turned off and some instrument voltages are turned off) at the end of a run.

09/01/2023    Academia Omics | Pharma CRO | NanoLC 400

How To Install the DIA-NN Software 1.8.1 To Process SCIEX WIFF Files?

To process SCIEX data files (.wiff) with the DIA-NN software, the DIA-NN software must be installed using the downloaded executable file. In addition to installing DIA-NN software, the ProteoWizard software must be installed and the dll files in the ProteoWizard installer folder named Clearcore and SCIEX must be transferred to the DIA-NN installer folder.

09/01/2023    Academia Omics | Software

What Is a DIA-NN Library-Free Search in a Data-Independent Acquisition (DIA) Proteomics Workflow on ZenoTOF 7600 System?

A library-free search, or direct-DIA (data-independent acquisition), is a proteomics strategy to identify unknown proteins and peptides by generating a theoretical spectral library from a FASTA file and then searching the DIA data against this spectral library using the DIA-NN software.

09/01/2023    Academia Omics | Software

Which Molecule Profiler Software Version Can Process EAD Fragmentation Data?

The Molecular Profiler software 1.3 is embedded in the SCIEX OS software version 3.1.6 and can assign structures by using fragments from both electron-activated dissociation (EAD) and collision-induced dissociation (CID) techniques.

09/01/2023    Academia Omics | Pharma CRO | Software

How Does the Channel Alignment Function on a SCIEX TripleTOF® System?

The purpose of channel alignment is to re-align the signals from each detector/TDC channel in time on a TripleTOF® system. Channel 2 is used as the reference channel, and a simple linear transformation is applied to the other three channels to align them to the refrence.

09/01/2023    Academia Omics | Pharma CRO | QTOF Systems

Canned Calculation for SANTE Guideline 12682_2019 - C16 - Available for SCIEX OS Software

This article provides information on the custom calculations required for processing data according to the guidance found in SANTE 12682_2019 - C16. The guidance requires that analyte response in the extracted pesticide samples should lie within the range tested for calibration standards. These calculations were created to provide a ready-made solution for determining which samples will need to be re-injected in pesticide reports.

08/31/2023   

Where Are the Report Templates Located for Analyst® Software?

To edit a report template or add a new template to create reports in Analyst® software, users must access the folder where report templates are stored. The report template files are located in the Templates sub-folder within the API Instrument project folder in the Analyst Data root directory.

08/24/2023   

How Do I Select a Compound Database in DiscoveryQuant™ Software?

To select a compound database in DiscoveryQuant™ software, select the Data menu, and then select Database Selection. The Compound Database Selection dialog will open, and the database options are indicated in this window.

08/24/2023    Software

What Are the Minimum Cycles Needed To Obtain Quality Optimizations in DiscoveryQuant™ Software?

When setting up an optimization experiment in DiscoveryQuant™ software, the minimum number of cycles needed to obtain quality optimizations is two.

08/24/2023    Software

How Are Entries Added to the Compound Database in DiscoveryQuant™ Software?

To add entries to the compound database in DiscoveryQuant™ software, the Edit Compound Workspace must be opened.

08/24/2023    Software

What Is the Username and Password for the Empty Compound Database in DiscoveryQuant™ Software?

To open the empty compound database - CompoundDB3.mdb - for DiscoveryQuant™ software, a username and password are required. The username is Admin and the password is !DQO2.

08/24/2023    Software

How Is the Analyst Response Factor Column Generated in SCIEX OS Software?

In the SCIEX OS Analytics workspace, Response Factor is not one of the standard columns that users can select from the results table, but it can be created and added to the results table by adding a custom column. 

08/24/2023    Software

Why Can't I Print My Audit Trail Record from Analyst® Software?

For Windows 10 operating systems, if the user who logs on to the Analyst® software in mixed mode is different than the user who logged on to the computer, then the audit trail record printing function will not be available.

08/24/2023    Software

How Can I Customize the Project Information in DiscoveryQuant™ Software?

To customize the project information in DiscoveryQuant™ software, open the Setup Optimization workspace.

08/24/2023    Software

Do Analyst® Software and Analyst Administrator Console (AAC) Support Cross-Domain Logins?

No, the Analyst® software and the Analyst Administrator Console (AAC) do not support cross-domain logins. The computer where Analyst software is installed, the AAC computer, and the network users should be on the same network domain.

08/23/2023    Software

Can I Create an API Instrument Project in a Shared Drive for Network Acquisition with Analyst® Software?

No, when using Analyst® software for network acquisition, users should not create a project with the name API Instrument in the network root directory. Doing so causes the instrument audit trail events to be recorded in the API Instrument project on the network instead of in the local API Instrument project.

08/22/2023    Software

How to perform System Check on Sciex Exion 1.0 systems from Analyst®

How to perform System Check on Sciex Exion 1.0 systems from Analyst®

08/18/2023   

How Can I Transfer an Acquisition Method from Analyst® to SCIEX OS Software?

To transfer or import an acquisition method (*.dam file) created in Analyst® software into SCIEX OS software, open the MS Method tile and then select Convert File. Only the MS experiment will be imported into SCIEX OS software. The LC method from Analyst software will need to be entered manually.

06/06/2023    SCIEX OS | Analyst Software

Instrument readbacks log from Analyst

Where to locate the instrument readbacks log from Analyst

03/16/2023   

Getting Started with OneOmics™ Suite 3.4

This article describes the required registration, browser setup, software setup, and first steps for uploading data to the Data Store in the web-based and cloud-powered OneOmics™ suite.

03/03/2023    Academia Omics | Software

Can I Install SCIEX OS and Analyst® Software on the Same Computer for Data Acquisition?

Analyst® software and SCIEX OS software can be installed on the same PC, but SCIEX does not support workflows that use both the Analyst and SCIEX OS software to acquire data from the same mass spectrometer.

03/03/2023    Software

Unknown Retention Time Values for Analytes in IDA Method Inclusion or Exclusion Lists in SCIEX OS Software

When setting up an information dependent acquisition (IDA) method, there is an option for including the retention time (RT) for analytes in an inclusion or exclusion list. In the inclusion/exclusion table, users can limit the masses in the list to a certain retention time with a specific width. However, sometimes the retention time is unknown, and its not clear what value to add for RT column.

03/03/2023   

Can the Installation Repair Tool in SCIEX OS Software Be Used for a Central Administrator Console (CAC) Software Install?

No, the Installation Repair Tool in SCIEX OS software can not be used to assess the installation of the Central Administrator Console (CAC) software.

03/03/2023    Pharma CRO | Software

What Are the New Visualization Features in the OneOmics Suite for DIA-NN Software Output Files?

The DIA Results app, a new software feature in the cloud-based OneOmics suite for processing DIA-NN software output (TSV file), helps visualize proteomics data so that protein quantification results can be interpreted in the Analytics and Browser sections.

03/03/2023    Academia Omics | Software

What Is the Maximum Length of Characters for the Path to the Installation Folder for SCIEX OS Software?

Please ensure that the path to the installation folder for SCIEX OS software is 118 characters or less. If it is longer, the installation of SCIEX OS software will not proceed.

03/03/2023    Software

Setting Up the LC Pressure Trace Monitoring for an Acquisition Method in Analyst® Software

Setting up the LC pump pressure trace and column oven temperature trace monitoring supported by Analyst® software 1.7.3 is explained here. The resulting pressure traces can be stored in the data file for each sample. 

03/03/2023    Software

Two New Tiles in the OneOmics™ Suite Support Data Processing with DIA-NN Software

The two new software tiles in the OneOmics™ suite are the Ion Library app and the DIA Results app. These apps are used to process data-independent acquisition (DIA) data acquired by the ZenoTOF 7600 system, along with the DIA-NN software module that is embedded in the OneOmics suite.

03/03/2023    Academia Omics | Software

How To Configure the OptiFlow® Turbo V Ion Source with the Microflow Probe for Nanoflow Rates

The OptiFlow® Turbo V ion source with the microflow probe can be configured for nanoflow rates, allowing for the continued use of the calibrant delivery system (CDS) for automated calibration.

03/03/2023    Academia Omics

How Do I Start the Installation Confirmation Tool in SCIEX OS Software?

SCIEX OS 3.1 software has an installation confirmation tool that ensures that the software has been installed correctly. The confirmation tool can be started by tapping or clicking Search on the taskbar and then typing "SCIEX OS Installation Confirmation Tool" in the search box.

03/03/2023    Software

What File Format Can Be Used for RNA Data Sets in the OneOmics™ Suite 3.4?

To import RNA data sets into the OneOmics™ suite, the RNA data sets need to be in the Cuffdiff output file format from CuffLinks.

03/03/2023    Academia Omics | Software

How to modify the Project Results Table Settings in Analyst

All available project results table settings can be accessed and modified via Tools.

02/28/2023   

Creating an Ion Library for DIA-NN Software Using the Ion Library Generator in OneOmics™ Suite 3.3

This article describes how to create an ion library for DIA-NN in the OneOmics™ suite 3.3 using the Ion Library Generator.

02/10/2023    Academia Omics | Software

What Are the New Features in the ProteinPilot™ Software Found in the OneOmics™ Suite 3.3?

This article describes the new software features recently implemented in ProteinPilot™ software 5.0.3 in the OneOmics™ suite version 3.3. The version of ProteinPilot software found in the OneOmics suite has nearly the same features as the desktop version of ProteinPilot software.

02/10/2023    Academia Omics | Software

How to use Mixed Mode in SCIEX OS

Explains the different Security Modes and how to use them. More details can be found in SCIEX OS Laboratory Directors Guide

02/07/2023    SCIEX OS

Troubleshooting Common LC Issues on SCIEX Triple Quad™ and QTRAP® Systems

Pressure issues, shifting retention times, and no peaks are common issues when running LC-MS methods. The guides linked tp this article provide step-by-step instructions to troubleshoot these common issues.

01/17/2023    QTRAP Systems | Triple Quad Systems

How Can I Tell if Zeno SWATH Pulsing Is Working Correctly on My ZenoTOF 7600 System?

To verify that Zeno SWATH pulsing is working on a ZenoTOF 7600 system, users should run a SWATH® acquisition method with and without additional Zeno pulsing using standards from the SWATH acquisition performance kit.

12/16/2022    Academia Omics | Pharma CRO

Troubleshooting the ZenoTOF 7600 System: In-Run Calibration Failures

If a calibration failure occurs while acquiring data on the ZenoTOF 7600 system, then certain measures can be followed to mitigate this issue. The troubleshooting guide provided in this article is a step-by-step path for resolving any problems with in-run calibrations. To begin troubleshooting in-run calibration failures, users should open the calibration report in the Analytics workspace of SCIEX OS software to identify the reasons behind the failure.

12/15/2022    QTOF Systems

How To Create a Metric Plot in Analyst® Software

In Analyst® software, there are multiple ways to view a metric plot in order to see trends quickly after generating a results table.

12/02/2022    Analyst Software

Communication Issues when Switching Between ExionLC and Eksigent Hardware Profiles in Analyst® Software

Switching from a hardware profile that contains an ExionLC (or Shimadzu LC) system to a hardware profile with an Eksigent LC when both LCs are connected to the PC can cause Analyst® 1.6.3 software to crash, resulting in communications issues.

Diverter Valve Would Not Work While Using Delay Time in Analyst® Software

The diverter valve will not work properly when using Delay Time in the acquisition method of Analyst® Software due to a mismatch between diverter valve timing and MS acquisition timing. This results in the diverter valve timing not aligning with the MS acquisition time.

Error In MultiQuant™ Software When Generating a CSV Report

The error "Cannot save report with graphical or table elements as a text/csv file" appears when attempting to generate a report as a CSV file in MultiQuant™ software using a report template that has figures, pictures, or tables. This is due to CSV reports not being able to display figures or tables.

12/02/2022    MultiQuant Software

Troubleshooting the ZenoTOF 7600 System: Tuning and Calibration

Before using the ZenoTOF 7600 system, users should run a system check to verify their instrument's performance. In the event that the MS Quick Status check fails, a link to a troubleshooting guide is included in this article.

12/02/2022   

Microsoft Office 365 Cannot Be Activated on SCIEX Acquisition PCs

Because of the version of Microsoft Windows that is installed, Microsoft Office 365 may not be able to be activated on certain SCIEX acquisition PCs.

12/02/2022    Software

How Can I Adjust the Dynamic CE Table in SCIEX OS Software?

Sometimes the dynamic collision energy (CE) for peptides needs to be adjusted to get better fragmentation of the precursor ion. This article describes how to adjust the dynamic CE table.

10/20/2022    SCIEX OS

How To Create Metric Plots In MultiQuant™ Software

To create a metric plot In MultiQuant™ software, users should highlight the column they wish to see plotted versus the sample index and then select the metric plot icon (trend line with red peaks) in order to view trends such as the peak area of internal standards and analytes.

10/20/2022    MultiQuant Software

What Fittings Are Needed To Add a Waters M-Class LC to My ZenoTOF 7600 System?

This article explains which fittings are needed to add a Waters M-Class LC to a ZenoTOF 7600 system and includes part numbers and pictures of tubing and trap loop connections.

10/17/2022    QTOF Systems

How To View Metric Plots in the Analytics Mode in SCIEX OS Software

To view trends (such as internal standard peak area) over a range of samples in a results table, a metric plot can be created in the Analytics mode of SCIEX OS software by selecting the column with the values of interest and then selecting Create metric plot from the More menu.

10/14/2022    SCIEX OS

How Can I Set the Integration Algorithm in the SCIEX OS Software?

To set the integration algorithm prior to processing quantitation data, select the Project Default Settings option in the Projects menu in the SCIEX OS software under the Analytics tile.

10/14/2022    SCIEX OS

How To Install Templates in Biologics Explorer Software

This article describes how to install the template packages in Biologics Explorer software.

10/14/2022    Academia Omics | Pharma CRO | Software

Device Driver Error During Acquisition with Analyst® Software While Using a Shimadzu LC-40 System

While acquiring data with Analyst® 1.7.3 Software while using a Shimadzu LC-40 system, the run will intermittently fail and the following error will appear: "Integrated System Shimadzu LC-40 Controller 0: ERROR: Operation failed. device driver exception." To resolve this error, Hotfix1 for Analyst 1.7.3 will need to be installed when it becomes available. Alternatively, change the LC method so that it is 0.1 min longer than the MS method.

10/14/2022    Analyst Software

Why Can't Users with Non-US English Language Settings Create an FDR Report in ProteinPilot™ Software?

When running a search in ProteinPilot™ software as an admin or non-admin user, there should be no difference in FDR report creation as long as full Windows permissions have been provided for Excel report creation. For ProteinPilot software version 5.0.2 with the latest patch (ProteinPilot 5.0.2 Patch for UniProt Issue - Rev. 2), users with a non-admin role may not be able to create reports if the language and font settings are not set to US English.

Can the SCIEX OS Software Central Administrator Console (CAC) Run on a Citrix Server?

The SCIEX OS Software Central Administrator Console (CAC) should run on a Citrix Server, but this configuration has not been tested and is not officially supported.

10/12/2022    Pharma CRO | Software

Will the SCIEX OS Software Central Administrator Console (CAC) Run on Windows Server 2019 in a Virtual Environment?

Yes, the SCIEX OS Software Central Administrator Console (CAC) software installed on a Windows Server 2019 will run in a virtual environment and is officially supported.

10/12/2022    Pharma CRO | SCIEX OS

How To Change Results Table Peak Review Settings in Analyst® Software

While reviewing a results table in the Quantitate mode of Analyst® software, the peak review settings can be changed to view more than one chromatogram and to adjust the x-axis and y-axis automatic zoom settings.

09/30/2022    Analyst Software

Custom Calculations or Flagging Rules Not Working after SCIEX OS Software Upgrade or Reinstall

After a reinstall or upgrade of SCIEX OS software, the custom calculations and flagging rules of a processing method may not work properly. A config file for the software will need to be edited to restore functionality.

09/30/2022    SCIEX OS

How Do I Open a Port in Windows Firewall for the Central Administrator Console (CAC) Software?

This article describes how to open the port for the Central Administrator Console (CAC) server when Windows Defender is used as the Windows firewall software.

09/30/2022    Pharma CRO | SCIEX OS

MultiQuant™ MD 3.0.2 Software Will Not Open and No Error Message Appears

If MultiQuant™ MD 3.0.2 software will not open when the desktop icon is selected and there is no error message appearing, this usually indicates that the software was installed on a non-compatible operating system. MultiQuant MD 3.0.2 software must be installed on Window 7, and it will not launch in a Windows 10 enviroment.

09/30/2022    MultiQuant Software

Data Not Visible for New Results Table Processing in SCIEX OS Software

To create a new results table in SCIEX OS software, users must browse to data sets (.wiff files) from the Analytics mode through the Results menu. When New and then Browse are selected to start a new results table, no data set is seen when the data folder is selected in the Select Folder menu. It appears as if the raw .wiff files are missing.

09/30/2022    SCIEX OS

Where Do I Put Query Files Used with Reporter Templates for MultiQuant™ or SCIEX OS Software?

Queries are used by report templates to process specific data from results tables in either MultiQuant™ or SCIEX OS Software. For a report template to utilize a query, the query file must be placed in the same directory as the report template.

09/30/2022    SCIEX OS | MultiQuant Software

Do I Have the Central Administrator Console (CAC) Server Installed for SCIEX OS Software on My PC?

Users can determine if the Central Administrator Console (CAC) server is installed on their PC by checking if the splash screen at startup displays the name SCIEX OS Central Administrator Console or by checking the About menu in the Configuration mode of the software. Also, one of the four workspace tiles on the home screen says Central Administration once the software loads.

09/30/2022    Pharma CRO | SCIEX OS

What Is the Minimum Accumulation Time in Analyst® TF Software for TripleTOF® Systems?

This article provides guidance on the minimum accumulation time that can be entered in Analyst® TF software for TripleTOF® Systems.

09/30/2022    Analyst Software

How To Review Statistics for Standards and QCs in Analyst® Software

To review the statistical information for standard and QC samples after creating a results table in Analyst® software, select the statistics button in the software's toolbar. This will open a new window with statistics for the standards and QCs that can be copy and pasted to a spreadsheet.

09/30/2022    Analyst Software

Is the Settings File for the Central Administrator Console (CAC) Software Forward Compatible?

Yes, the Central Administrator Console (CAC) software settings are forward compatible with future versions of the CAC for SCIEX OS software. This means that the setting files (.eac files) from older versions of the CAC software can be imported into newer CAC versions (when they become available), and all the information regarding users, workstations, projects and workgroups will be able to imported into a new version or new installation of the CAC software.

09/30/2022    Pharma CRO | SCIEX OS

Can I Install the Central Administrator Console (CAC) Software on a Server Also Running a FlexNet Licensing Server?

Yes, the SCIEX OS software Central Administrator Console (CAC) software can reside on the same server as the FlexNet Licensing Server.

09/20/2022    Pharma CRO | SCIEX OS

Is a Special Administrator Account Required for the Central Administrator Console (CAC) Software?

A special administrator account is not required for the Central Administrator Console (CAC) software. The CAC server uses the standard SCIEX OS software roles to manage CAC administration permissions.

09/20/2022    Pharma CRO | SCIEX OS

MultiQuant™ Software: Concentration Upper Limits Flag Incorrectly Assigned when No Peak Detected

In Multiquant™ software using a quantitation method with upper limits for concentrations set causes samples with N/A for peak area to be flagged for concentration.

09/16/2022    MultiQuant Software

How Many Client Workstations with SCIEX OS Software Does the Central Administrator Console (CAC) Software Support?

The Central Admin Console (CAC) software can support 100 client workstations with the SCIEX OS software installed.

09/16/2022    Pharma CRO | Software

What Happens to the SCIEX OS Software when the License for the Central Administrator Console (CAC) Software Expires?

If the license expires for the Central Administrator Console (CAC) software, the server data is maintained in the CAC database, but users won’t be able to launch the CAC application. The SCIEX OS software installed on the client workstations will continue to launch and work with last retrieved data while the CAC server is not reachable.

09/16/2022    Pharma CRO | SCIEX OS

Fatal Error in MultiQuant™ Software: The File or Directory Is Corrupted and Unreadable

While opening a file or creating a results table in MultiQuant™ software, users may receive the error message "The file directory is corrupted and unreadable." Running the Windows file explorer drive check can resolve this issue.

09/16/2022    Software

Internal Standard Recovery Calculations in MultiQuant™ and SCIEX OS Software

SCIEX OS and MultiQuant™ software both calculate internal standard (IS) recovery but use different approaches. SCIEX OS software uses a built-in functionality for creating custom formulas to calculate IS recovery. MultiQuant™ software requires a query to be applied to the results table to perform the IS recovery calculation and to add a custom IS recovery column to the results table.

09/16/2022    SCIEX OS | MultiQuant Software

How To Change Chromatography Peak Shading In MultiQuant™ Software

To change how peaks are shaded in MultiQuant™ software in the Peak Review section, right click on the chromatogram and click on Options. Under the Appearance tab, there will be a drop-down section for Fill Peaks.

09/16/2022    MultiQuant Software

How to Export the Settings for the Central Administration Console (CAC) Software

Users can export the security settings from a Central Administration Console (CAC) server used to manage SCIEX OS software users and projects. The settings are exported as an ECAC file and can be imported into another CAC server installation to transfer the security settings. 

09/16/2022    Pharma CRO | SCIEX OS

What Are the Hardware Specifications for the Central Administrator Console for SCIEX OS Software?

The hardware recommendations for the Central Administrator Console for SCIEX OS software are for a PC with a minimum of an i5 quad core, a 3 GHz processor or above, a minimum of 20 GB hard drive space, and a minimum of 8 GB RAM.

09/16/2022    Pharma CRO | SCIEX OS

Where is the Database for the Central Administrator Console (CAC) Software Stored?

Central Administrator Console (CAC) software is used to create and manage projects and users for laboratories using SCIEX OS software on multiple workstations and instruments. The CAC software database is stored in the following location: C:\ProgramData\SCIEX\Clearcore2.Acquisition\CacServerDataBackup

09/16/2022    Pharma CRO | SCIEX OS

How Does a Client PC Connect to the Central Administrator Console (CAC) Server?

The Central Administrator Console (CAC) software client connects to the CAC server using TCP ports 63333 and 44144. Users need to open the Windows firewall port when Windows Defender is used as the default firewall software. If different firewall software is used, then users must follow instructions specific to that software to open these ports.

09/16/2022    Pharma CRO | SCIEX OS

Unable To Connect to Shimadzu LC In Hardware Configuration in Analyst® Software

When trying to activate a newly installed Shimadzu LC in a hardware configuration in Analyst® Software, an error will appear stating that the LC could not be connected.

09/16/2022    Analyst Software

Where Are the Log Files Located for ProteinPilot™ Software?

The log files are needed for troubleshooting error messages in ProteinPilot™ software and can be located at C:\AB SCIEX\ProteinPilot Data\Temp\ProteinPilot.log.

How Can I Install the Free Extractables & Leachables Library in SCIEX OS Software?

This article describes how to download and install the free Extractables & Leachables library into SCIEX OS software to test a library matching workflow.

09/16/2022    SCIEX OS

Adding a New Fragmentation Rule for EAD Data from a ZenoTOF 7600 System to the Mascot Server

The steps for adding Mascot server fragmentation rules for an electron activated dissociation (EAD) cell on a ZenoTOF 7600 system are discussed in this article, as well as how to set up these rules in the Mascot Daemon client software version 2.6 or 2.8.

09/14/2022    Academia Omics | Mass Spectrometers

Unable To Change Sample Loop Volume With Analyst® Hardware Configuration For ExionLC™ AD System

After replacing the sample loop for a different volume on an ExionLC™ AD system, the volume of the loop can be changed on the LC controller panel but not within Analyst® software hardware configuration.

09/14/2022    ExionLC AD | Analyst Software

Valve Model Will Not Stop Equilibrating In SCIEX OS Software 2.1

When equilibrating any MS method on a SCIEX 7500 system, the "Valve Model" will never finish equilibrating even after the specified time when using SCIEX OS software 2.1.

09/14/2022    SCIEX OS | Triple Quad Systems

How Can I Get a Biologics Explorer Trial License?

To obtain a Biologics Explorer (BE) 1.x trial license, send an email to biologics.explorer.orders@sciex.com with a request for a 30-day trial.

09/14/2022    Academia Omics | Pharma CRO | Software

How to Electronically Reset a SCIEX 7500 System

This article describes the steps for resetting the SCIEX 7500 series instruments.

Implementing Zeno SWATH Functionality on the ZenoTOF 7600 System

To enable the Zeno SWATH pulsing function in the SCIEX OS software for the ZenoTOF 7600 system, upgrade the software to version 3.0 and then add the Zeno SWATH extension license for SCIEX OS software.

09/14/2022   

Clearing an Integrated Syringe Pump Error in Analyst® Software

Different approaches are provided here to resolve an error message that appears in Analyst® software while using the integrated syringe in manual tune mode: "The current sample cannot be run because the syringe pump has reached the end of its travel. To solve this problem please refill the syringe, press "Clear Error" and resubmit the sample".

09/14/2022    Analyst Software

Resolving the Error "Unexpected Error Has Occurred" when opening Reporter In Analyst® Software

When opening Reporter in Analyst® software, an error message appears reading "Unexpected error has occurred."

09/14/2022    Analyst Software

Analyst® Software Error: Please Enter Positive Numeric Value Only

While attempting to select manual tune mode, users of Analyst® software may see the error message "Please enter positive numeric value only." This error results from commas instead of periods being used as decimal points in non-English based operating systems.

09/01/2022    Software

Can Results Tables Created in MultiQuant™ Software Be Opened in SCIEX OS Software?

It is not possible to open a results table (.qsession file) that was generated in MultiQuant™ software in SCIEX OS software.

08/31/2022    Software

Transferring Acquisition Methods Between Analyst® Software and Analyst MD Software

Is it possible to move an acquisition method that was created in Analyst® software to Analyst MD software?

08/10/2022    Software

Issue with Ion Ratio Calculations in MultiQuant™ Software 3.0.3 Resolved with HotFix 2

When removing a standard from the calibration curve of an analyte in MultiQuant™ Software 3.0.3, an error occurs where the ion ratio for analytes farther down the list gets improperly calculated and changed. This issue is resolved by installing HotFix 2.

08/08/2022    MultiQuant Software

How Do I Convert Acquisition Methods Created in Analyst® Software for Use in SCIEX OS Software?

Users can convert existing acquisition methods created in Analyst® software for use in SCIEX OS software by using the Convert File option in the Open menu in the MS Method tile. Only the MS portion of the method will be converted; there is no conversion function for the LC portion of the method.

08/08/2022    Mass Spectrometers | Software

How Do I Find the Build Number for Analyst® Software Version 1.7.3?

With Analyst® software version 1.7.3, the build number no longer appears in the About Box due to a new requirement that the displayed information in Analyst 1.7.3 had to be in sync with the MD version of the software. Users can check the version (build) number by navigating to the Programs and Features section of the control panel by using the Details view to see the version for each installed software.

08/08/2022    Software

How to create a new Wellplate in SCIEX OS for Agilent Autosampler

Will explain how to use an existing wellplate to modify accordingly to be able to use a new customized wellplate for Agilent Infinity II Multisampler. Same procedure will also works for other Agilent Autosampler, but have some slightly different names for some of the steps.

08/04/2022   

Special Acquisition Account (SAA) - a must have for Network Acquisition with Analyst in a regulated environment

This article explain what a Special Acquisition Account is, when to use and how to set it up properly for Analyst Software. This is valid for all Analyst versions from 1.0 up to latest 1.7.3. Also in a non regulated environment, it is recommended to use SAA if Acquiring into a Network.

08/04/2022    Analyst Software

Unable to Export IDA Table From SCIEX OS Software into Excel

When viewing IDA data in the Explorer mode of SCIEX OS software, the IDA table data will not export into Excel. Exporting the data directly to Excel is not supported in SCIEX OS software, and the best workaround is to select the top row of the table and select Ctrl, Shift, End to copy the IDA data directly to Excel.

07/23/2022    SCIEX OS

What Happens During Q0 Dissociation when "Simple" or "Enhanced" Options Are Used in SCIEX OS Software?

Declustering is achieved with the SCIEX Triple Quad 7500 system using a voltage differential between the QJet® ion guide and the IQ0 lens or a voltage differential between IQ0 and Q0 (the quadrupole ion guide before Q1). This article explains how Q0 dissociation is achieved using simple or enhanced modes in the SCIEX OS software and how the D Jet™ ion guide is involved in enhanced-mode dissociation.

06/22/2022    SCIEX OS | Triple Quad Systems

Can the Lipidyzer™ Platform Be Upgraded to a Windows 10 Compatible Version?

Lipidyzer™ platform 1.0.5 is only Windows 7 compatible, and there are no upgrades available that allow the software to be used on a Windows 10 system.

Unable to Install MultiQuant™ Software 3.0.3 on Windows 10 Version 20H2

MultiQuant™ software 3.0.3 is not compatible with and cannot be installed on Windows 10 version 20H2. In order to install MultiQuant software 3.0.3, Windows 10 must be downgraded to an earlier version.

06/22/2022    Software

Download a Free Ion Library for LibraryView™ Software

A free-of-charge ion library for LibraryView™ software is available from the SCIEX Software Downloads page. No license is required to use the Accurate Mass E&L Open Access HR-MS/MS Spectral Library, the so-called Extractables & leachables library.

06/22/2022    SCIEX OS | LibraryView Software

How to Activate the Molecule Profiler Software Module in SCIEX OS Software

The Molecule Profiler software is a processing-only software module within the SCIEX OS software suite that can identify and characterize parent molecules and their metabolites. Activating the Molecule Profiler software version 1.1 simply requires the installation of an additional license; however, activation of version 1.0.1 requires an additional software download as well as license installation.

Can I Use the SWATH® Variable Window Calculator 1.2 with All SCIEX QTOF Systems?

The SWATH® Variable Window Calculator 1.2 is a new updated calculator that supports all SCIEX QTOF instruments with Analyst® TF and SCIEX OS software versions.

What Are the Current Limitations of the SWATH® Variable Window Calculator Tool?

The SWATH® Variable Window Calculator tool can be used with Analyst® TF 1.7 software and SCIEX OS 1.7 software and higher for many QTOF instruments. This article lists the maximum target number of Q1 windows and the maximum upper m/z limit for each QTOF instrument.

Can Analyst® and SCIEX OS Software be Installed on Separate Computers and then Used Alternately for Acquisition?

Switching between Analyst® and SCIEX OS software for acquisition, either on the same or different computers, is not a supported workflow.

Can Both Analyst® Software and SCIEX OS Software be Used for Acquisition on the Same PC?

No, Analyst® and SCIEX OS software cannot be used for acquisition on the same computer. Analyst software will be removed from an acquisition PC if it is upgraded to use SCIEX OS software for acquiring data.

Are Validation Services Available To Install and Test the SCIEX OS Software in My Lab?

Yes, the SCIEX validation services team has helpful and cost-effective services for SCIEX OS software validation.

Upgrading a SCIEX Triple Quad system to use SCIEX OS software as the acquisition software (replacing Analyst® software) is a paid software upgrade and requires an engineer install the software and upgrade the firmware. To get more information about available options, please contact your sales associate.

How to Report Regression Parameters in a Results Table Created in SCIEX OS Software

Regression parameters values (e.g., r squared, slope, linear coefficient) can now be added to a results table created in SCIEX OS software from the calculated columns that are saved under the processing method.

05/18/2022    SCIEX OS

Can Audit Maps Be Easily Transferred from Analyst® Software to SCIEX OS Software?

No, audit maps cannot be directly transferred from Analyst® to SCIEX OS software.

05/18/2022    Pharma CRO | Software

Are There Differences in LIMS Column Headers between Analyst® and SCIEX OS Software?

As users switch from Analyst® to SCIEX OS software, there may be concerns about column header or formatting differences between the two software versions when importing or exporting information using a LIMS. Although similar, there are format and column differences between the SCIEX OS and Analyst software systems, and SCIEX can provide examples for both formats.

Is the SelexION® Device Compatible for Acquisition with SCIEX OS Software?

No, the SelexION® device is not yet supported in SCIEX OS software.

05/18/2022    Pharma CRO | Software

Do I Need To Revalidate My Software Workflow after Upgrading from Analyst® to SCIEX OS Software?

Yes, the software workflow will need to be revalidated after upgrading from Analyst® to SCIEX OS software. SCIEX OS software is a completely different software platform than Analyst software, and because even minor changes require revalidation, the switch from Analyst to SCIEX OS software will also require a revalidation.

05/18/2022    Pharma CRO | Software

Does the SCIEX 7500 System with SCIEX OS Software Work with StatusScope® Remote Monitoring Service?

Yes, the SCIEX 7500 System with SCIEX OS Software is compatible with StatusScope® remote monitoring service version 2.0.

Converting WIFF2 Files from SCIEX OS Software to the mzML and mzXML Format

The ProteoWizard tool (http://proteowizard.sourceforge.net/downloads.shtml) for mzML and mzXML conversion has been updated to work with the WIFF2 files that are produced by SCIEX OS software.

05/17/2022    Analyst Software

Can I Modify or Add an Enzyme in Bio Tool Kit Software?

The Bio Tool Kit software micro-app characterizes biomolecules within SCIEX OS and PeakView® software through features such as intact protein spectral deconvolution and manual sequence tagging. The software does not allow users to add or modify proteolytic enzymes themselves, but there is a workaround that can be used to modify an existing enzyme.

How to Generate a Service Package in Analyst® Software

Generating a service package allows the technical support team to pinpoint and resolve software issues more quickly. To diagnose an issue with Analyst® software, download and install the Analyst Diagnostics Tool (ADT).

05/06/2022    Analyst Software

Locating the Computer ID(s) on a PC with a Windows Operating System

The computer ID, also known as the physical or MAC address, is a number used when activating a software license on Sciex.com and contains a series of 12 characters followed by a space and then another 12 characters. This article explains a few different ways to generate the computer ID on a Windows 10 system. (These same steps apply to a Windows 7 system as well.)

05/06/2022    Software

Exporting Mascot Searches from QTOF and MALDI TOF/TOF™ Systems for PRIDE Submission

Mascot searches can be exported from the Mascot server; but the data needs to be converted to the mzIdentML file format and then submitted to PRIDE. This article only describes how to export a Mascot search.

05/06/2022    Academia Omics

How to Save Application and System Event Logs in Windows 10

The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps in Analyst® software to save your system and application event logs so that they can be analyzed by the SCIEX support team.

05/05/2022    Software

What is the Maximum Sampling Speed of the Echo® MS System?

There are two modes for the Echo® MS system, normal and fast. The normal mode maximum sampling speed is 1 sample/s. In fast mode, the maximum sampling speed is 3 samples/s.

05/05/2022    Pharma CRO | Software

When Does Analyst® Software Start Generating the Archive for Audit Trail Records?

Once the instrument audit trail or a project audit trail contains 1000 audit records, the Analyst® software automatically archives the records and begins a new audit trail.

05/05/2022    Analyst Software

Setting Up Email Notifications and Emailed Reports in Cliquid® Software

To set up email notifications in Cliquid® software, launch the software and select the User Profile option. To start email notifications and the option to have reports emailed, the user's email address will need to be entered in the user profile.

05/04/2022    Clinical | Software

What Sample Plate Formats Are Supported on the Echo® MS System?

The Echo® MS System is only compatible with specialized, acoustically clear microplates that were specifically designed to ensure the optimal and repeatable performance of droplet ejection. These specialized plates are available in both 384- and 1536-well formats.

05/04/2022    Pharma CRO | Software

How to Export and Import Processing Methods in SCIEX OS Software

Processing methods can be exported or imported in the Analytics workspace of SCIEX OS software.

05/04/2022    SCIEX OS

Creating a Hardware Profile in Simulation Mode in SCIEX OS Software

To create a hardware profile in simulation mode in SCIEX OS software, select Simulate Device under the Settings tab when adding instruments to a hardware profile in the Configuration mode.

05/03/2022    SCIEX OS

How to Restore the Batch Rack Code in Analyst® Software when Using CTC Autosampler

While creating a batch in Analyst® software with a CTC autosampler in the hardware profile, the drop-down menus appear blank for rack position, plate position, and plate code and do not contain the usual text selections. Reselecting the rack code value of 1 will restore the drop-down menu text.

05/03/2022    Analyst Software

Setting Up Manual Integration (Percentage Rule) in SCIEX OS Software

To set up the parameter Manual Integration (Percentage Rule) in SCIEX OS software, a results table and peak review will need to be open in Analytics mode. In the peak review pane, select the Peak review display settings button under the Options menu. Then select the Appearance tab. The manual integration percent rule can be set by clicking the drop down arrow as shown below.

How to Create an Ion Ratio Flag in a Report Template

To flag an ion ratio as pass or fail in a report, an If/Else statement needs to be added using the MQ_Ion_Ratio tag.

05/03/2022    SCIEX OS | Analyst Software

Setting the Security Configuration to Single User Mode in Analyst® Software

To set the security configuration to single-user mode in Analyst® software, navigate to the Configure mode, and then select the Security Configuration option. Select More from the bottom left side of the splash screen, and then select the Security tab at the top of the screen. Under the Security Mode tab, choose the Single User Mode option. Click Apply and OK.

05/03/2022    Analyst Software

Returning the Results Table Settings to Defaults in Analyst® Software

If custom settings are applied to a results table in Analyst® software, they can be reversed by selecting the default settings option. To do so, right click within the results table to generate a secondary menu. Select the Table Settings option and then select Default.

05/03/2022    Analyst Software

How to Remove "No Data" from Report Output Generated from SCIEX OS Software

An IF/ELSE statement can be created to filter out the “No data” response in a report in SCIEX OS software.

04/04/2022    SCIEX OS

How is the GETSTAT Function Used in SCIEX OS Software?

The calculated columns for a processing method in SCIEX OS software allow users to add a formula that pulls the statistics pane calculations into the results table as a custom column. This can be done using the GETSTAT function.

04/01/2022    SCIEX OS

Can a Method Built in MPX™ Software Be Converted to a Method Used with SCIEX OS Software?

No, methods built in MPX™ software cannot be converted for use in SCIEX OS software. Files built in MPX software are not supported in SCIEX OS software.

04/01/2022    Clinical | Software

Is It Possible To Convert an Acquisition Method Built in Analyst® Software to a MS Method for SCIEX OS Software?

A MS acquisition method built in Analyst® software cannot be opened directly in SCIEX OS software 2.2, but it can be converted to a usable MS method in SCIEX OS software using the Convert file feature in the MS Method workspace.

Changing the Comparison Sample Assignment in Analytics in SCIEX OS Software

When reviewing a results table in the Analytics workspace of SCIEX OS software, users can change the comparison sample assignment from the one that was originally included in the processing method by selecting the option, Use the selected sample as the comparison sample.

What Are the Specifications for Installing SCIEX OS Software 2.2 on an Acquisition PC?

To install SCIEX OS software version 2.2 on an acquisition workstation, the PC needs to meet specific requirements. The following PCs are supported: 1) SCIEX workstation or workstation+ and 2) SCIEX Alpha workstation 2020.

Is the Database for DiscoveryQuant™ Software Limited to 1 GB?

Yes, the size of the Microsoft Access database file is limited to 2 GB. However, the reliability of the database degrades before reaching the 2 GB limit, so it is suggested that DiscoveryQuant™ software users create a new database before the database exceeds 1 GB.

04/01/2022    Pharma CRO | Software

Can a Processing Method Built in ChemoView™ Software Be Converted for Use in SCIEX OS Software?

No, a processing method built in ChemoView™ software cannot be converted for use in SCIEX OS software. Files built in ChemoView software are not supported in SCIEX OS software.

04/01/2022    Clinical | Software

Can a Method Built in Cliquid® Software Be Converted to a Method for SCIEX OS Software?

No, methods built in Cliquid® software cannot be converted for use in SCIEX OS software. Cliquid software method files are not supported in SCIEX OS software.

04/01/2022    Clinical | Software

Is Watson LIMS Software 7.6.1 SP1 Compatible with Analyst® Software 1.7.2 on Windows 10?

Yes, Watson LIMS software 7.6.1 SP1 is compatible with Analyst® software 1.7.2 on Windows 10. Please run as administer when installing both the Watson and the Analyst software to ensure LIMS integration between the two.

03/11/2022    Pharma CRO | Software

Enabling and Disabling the Data File Checksum Feature in SCIEX OS Software

To enable or disable the data file checksum feature in SCIEX OS software, navigate to the Configuration workspace in SCIEX OS software. Under the Projects tab under Data File Security, select the checkbox for Enable checksum writing for wiff data creation.

03/11/2022    Pharma CRO | Software

Where Are the SCIEX OS Software Project Audit Trail Archives Stored?

The audit trail records for a SCIEX OS software project are stored in the Audit Data sub-folder for the project. The audit trail file name is ProjectAuditEvents.atds.

03/11/2022    Pharma CRO | Software

When Does SCIEX OS Sofware Start Archiving Audit Trail Records?

In SCIEX OS software, the audit trail will be archived when it reaches 20,000 records.

03/11/2022    Pharma CRO | Software

How To Reset a QTOF System Mass Spectrometer

Power cycling a QTOF mass spectrometer can help resolve communication issues. The The TripleTOF® system, the X500 QTOF system, and the ZenoTOF system instruments (X500-, 5600-, 6600- and 7600-series instruments) are all reset in the same way. This article describes the reset procedure for these instruments.

02/25/2022    QTOF Systems

Where Are Acquisition Method Files (Both LC and MS) Saved for SCIEX OS Software Projects?

Each SCIEX OS software project has its own, separate MS and LC acquisition method files. This article describes where the method files are typically stored.

02/25/2022    SCIEX OS

Where Is Guided Optimization Found in the SCIEX OS Software?

The SCIEX OS software offers various guided optimization methods in the MS Method mode.

02/18/2022    SCIEX OS

Can a WIFF or WIFF2 File from SCIEX OS Software Be Split into Subset Data Files?

There is currently no script or software that allows for splitting a multi-sample data file from SCIEX OS software (i.e., .wiff or .wiff2) into individual subset files.

02/18/2022    SCIEX OS

Should I Revalidate My Software?

Periodic reviews of validated systems must be performed to ensure that no changes have been made that affect the validated state of the system. If there is a change, then the software needs to be revalidated.

02/11/2022    Software

What Do SCIEX Validation Services Include?

SCIEX qualification services include testing and documentation that demonstrates that the instrument is operating correctly and includes objective evidence showing what was tested, the specification for each test, and the results.

02/11/2022    Software

How Can I Export Results Table Data in Encrypted Text Files in SCIEX OS Software?

Users with the administrator role have access to the project settings for secure export in the Analytics workspace under the Projects drop down menu in the SCIEX OS software.

02/11/2022    SCIEX OS

Will Software Validation Ensure that Our Lab Is 21CFRpart11 Compliant?

The SCIEX software validation service ensures that Analyst® software is configured correctly, that the necessary procedures are documented, and that objective evidence of these activities is provided to ensure 21CFRpart11 compliance.

02/04/2022    Software

What Normalization Can I Use in MarkerView™ Software 1.3.1 when Processing My Peptide Data?

MarkerView™ software 1.3.1 software has a new Most Likely Ratio (MLR) normalization algorithm incorporated info this newest version of the software.

Can Biologics Explorer Software Be Installed on a PC with One Partition?

Biologics Explorer software needs to be installed on a computer with both a C: and D: drive partition; however, it is also possible to install this software on a PC with just one (C: drive) partition if a patch is also installed.

Can I Use the TOMKit Library with SCIEX OS and/or LibraryView™ Software?

The TOMKit Libraries are newer library entities, and they are not compatible with SCIEX OS or LibraryView™ software. The TOMKit libraries are for use with Agilent instruments only currently.

12/15/2021   

Building a Quant Method in SCIEX OS Software for DAD Data

Peaks from DAD or UV chromatograms that were acquired during an LC/MS experiment can be quantified in SCIEX OS software. Open a new quantitation method in SCIEX OS software, and then select the representative sample. On the Components tab, select the drop down menu in the Experiment Index column. Select the DAD experiment for each transition and add the desired wavelength to quantitate in the Start - Stop (Wavelength) column.

12/15/2021    SCIEX OS

My Annual SCIEX License Suddenly Stopped Working Before It Expired, Why?

A new annual SCIEX subscription license stopped working suddenly despite having many months of use remaining.

12/15/2021    Software

Is It Possible to View Extracted Ions in Separate Panes in SCIEX OS Software?

To show extracted ions in SCIEX OS software, the data file must be opened in the Explore module and then Ctrl+E is used to extract the ions of interest. The Split Traces into Separate Panes option in the Graph menu allows for the extracted ions to be displayed in separate panes.

12/15/2021    SCIEX OS

How to Print an XPS Report after Running MS Tune in SCIEX OS Software

To print the XPS report from the most recent or a prior tuning in SCIEX OS software, navigate to this location: D:\SCIEX OS Data\Optimization and then print the file report.xps.

12/15/2021    SCIEX OS

DiscoveryQuant™ Software Produces SQL Error during Migration from Windows 7 to Windows 10

To resolve an error that prevents the SQL database from connecting with DiscoveryQuant™ software 3.0.2 in Windows 10, SQL user accounts with the password enabled must be used.

12/15/2021    DiscoveryQuant Software

Extra Backslashes Added when Using Network Location for Root Directory in Analyst® Software

If extra backslashes are added to a network location for a root directory for Analyst® software, a registry edit will be needed to prevent this issue from continuing to occur. The extra backslashes in the data file name can cause errors when trying to create a new project or save files (including results tables).

12/15/2021    Analyst Software

Compounds Need to be Assigned to a Library to be Recognized in Cliquid® Software

A MS/MS spectra was added to a compound record in LibraryView™ software, but subsequent confirmation runs in Cliquid® software failed. The root cause of the issue was the compound in the LibraryView software database was not associated with any named library.

Password Guidance for Secure Network Account or Special Acquisition Account for SCIEX OS or Analyst® Software

This article provides some guidance for using a secure network account (SNA) with SCIEX OS software or a special acquisition account (SAA) with Analyst® software.

12/13/2021    SCIEX OS | Analyst Software

Analyst® TF Software Error: Instrument Optimization Parameters Are Not Available

If the error message "Instrument optimization parameters are not available" appears when running Analyst® TF software, check the region and language settings and ensure that English (United States) is set as the default language in the Windows operating system settings.

12/13/2021    Analyst Software

Generation of a New Root Directory for SCIEX OS Software Called C:\ClearCore Data

Some users have reported the appearance of a new root directory created by SCIEX OS software that is not on the D: partition where the root directory (D:\SCIEX OS DATA) is typically located, but rather on the C: drive. This C: drive root directory has a different name (C: \Clearcore Data) and does not match the root directory that appears in the Configuration mode of SCIEX OS software in the Projects menu.

12/13/2021    SCIEX OS

Is It Possible To Convert a Shimadzu High-Flow LC to a Microflow LC System?

In order for a microflow LC system to perform optimally, the correct LC hardware must be installed. For example, a high-flow Shimadzu LC-20AD system cannot simply be converted to a microflow system because the 20AD is not equipped with the correct type of solvent mixer.

12/09/2021    Pharma CRO

Mapped Network Drive Issue when Using SCIEX OS Software Version 2.1.6

Many customers reported issues when using a mapped network drive to store for data for SCIEX OS software version 2.1.6; however, if the data was download to a local drive, no errors were received.

12/07/2021    SCIEX OS

Why is Scheduled Ionization in Analyst® TF Software 1.8 Not Working with the OptiFlow® Turbo V Ion Source for Nano Flow?

Scheduled ionization in Analyst® TF software 1.8 is not configured to work optimally with the OptiFlow® Turbo V ion source ion source for nano flow. When using the OptiFlow® Turbo V ion source, scheduled ionization is always on, except when the start time in Analyst software is set to zero during pre- and post-run times. This is an issue for the nano spray users, because they will be unable to have the voltage stay on between runs for perpetual spray.

12/06/2021    Academia Omics | Analyst Software

How to Check if Unknown Samples Are Within Calibration Curve Range in SCIEX OS Software

To check if unknown samples are within the calibration curve range in a SCIEX OS software results table, additional calculated columns will need to be added to the results table.

12/05/2021    SCIEX OS

How Do I Select a Library and Perform a Library Search in SCIEX OS Software?

To select a library to use with a targeted or non-targeted screening method in SCIEX OS software, open an existing processing method or edit an embedded method from a results table. Ensure that the checkbox for Quantitation and targeted identification or for Non-targeted screening is selected. Then navigate to the Library Search option to set the library search parameters.

12/05/2021    SCIEX OS

Why Is There No MRMHR Scan Type when Using the Method Wizard for a TripleTOF® LC-MS/MS System?

This article describes the MRMHR workflow for a TripleTOF® LC-MS/MS System using the Method Wizard in Analyst® TF or SCIEX OS Software. MRMHR is not a scan type. It is a description for a set of looped experiments, which can be used for a targeted approach. The looped experiments include a TOF-MS experiment followed by dedicated product ion experiments either in high-resolution or high-sensitivity mode.

Decreasing Run Time when Using the LCMS Reconstruct Algorithm in ProteinPilot™ Software

This article describes how to modify the configuration file for ProteinPilot™ software to decrease the time needed when using the LSMS Reconstruct algorithm, especially when performing large protein ID searches on data sets from a TripleTOF® 6600 LC-MS/MS System.

What is the Signal-to-Noise(S/N) Integration Threshold in SCIEX OS Software?

A signal-to-noise (S/N) integration threshold was introduced in SCIEX OS software version 2.1.6, which allows users to select peaks for integratin based on the S/N ratio.

12/05/2021    SCIEX OS

How Can I Sum Vitamin D2 and D3 in SCIEX OS Software?

To add the calculated concentrations for vitamin D2 and D3 together and calculate the total vitamin D, a custom calculation in SCIEX OS software will need to be created in the processing method in the Analytics mode. The calculation will add custom column named Total VitD to the results table and provide a sum of the values for the calculated concentrations for vitamin D2 and D3.

12/05/2021    SCIEX OS

Reporter Error: Cannot Retrieve Analyte: the Specific Index ("-1") Is Out of Range

If the following error is received when creating a report for a results table in MultiQuant™ or SCIEX OS software "Cannot retrieve analyte: the specific index ("-1") is out of range", ensure that the individual tags within the loop are for the same sample type (e.g., use internal standard tags if For Each Internal Standard is used for the loop).

11/22/2021    SCIEX OS

Chromatograms Are Not Appearing in Reports Created with Reporter Template Suite

When using MultiQuant™ or SCIEX OS software to create a report with Reporter Template Suite software, chromatograms are not appearing in the report. Instead, the report shows the text "This image is not available" where the image should appear. If the tag, Picture: Peak Review, is used, then the Label field must contain a value that matches the name of a column in the results table or it must be blank.

11/22/2021    Analyst Software

Reporter Template Suite Software: The Summary Table Always Starts on the Second Page

When a report is generated from a results table in MultiQuant™, Analyst® or SCIEX OS software, the summary table will only start appearing on the second page of the report, and the first page is left blank after the header. To resolve this issue, open the report template and select and highlight the summary table. In the Microsoft Word Layout menu, select Paragraph. De-select the option Keep with next.

11/14/2021    SCIEX OS | MultiQuant Software

Adding a Custom Column to a Results Table in SCIEX OS Software

To add a custom column to a results table in SCIEX OS Software, select Add custom column from the More menu. Provide a name for the custom column and then select OK.

11/14/2021    SCIEX OS

Reporter Template Suite Software: How Do I Get Rid of "No Data" in Report if Sample Comment Is Empty?

When using the Reporter Template Suite Software with MultiQuant™, Analyst® or SCIEX OS software, the report output may indicate "no data" in the sample comment column if there is no text in the corresponding column in the results table. To eliminate "no data" as a response in the report, try using the following IF/ELSE statement: IF EMPTY($Sample_Comment) (Text Field: none) ELSE (Text Field: Sample Comment)

How to Export Results for Specific Analytes from SCIEX OS Software

To report only the results for specific analytes from SCIEX OS Software, a results table will first need to be opened in the Analytics mode. Start by selecting one of the analytes of interest from the Components and Group Tab. If multiple analytes need to be reported, then select additional analytes by holding the Ctrl key down and selecting each additional analyte with the mouse. Then in the Reporting menu, select Export Results > Export and Save Results Table.

11/10/2021    SCIEX OS

Cliquid® Software Does Not Show Quantitation Values for Qualitative Transitions in the Sample List

When Cliquid® software is used to submit samples, the sample list shows only the group name instead of each individual transition (e.g., only Testosterone is shown, instead of Testosterone 1 and Testosterone 2) so only one concentration from one transition can be added. To ensure that Cliquid software reads the full transition name, an underscore in between the name and number must be added (e.g., Testosterone_1 and Testosterone_2).

11/10/2021    Cliquid Software

What Are the Standard Addition Columns in a SCIEX OS Software Results Table?

Sciex OS software allows users to process standard addition results by selecting the Standard Addition option in the Components tab of the processing method in the Analytics mode. What do the new standard addition column headers mean?

11/04/2021    SCIEX OS

How to Setup Standard Addition in SCIEX OS Software

If the standard addition feature is enabled in SCIEX OS software, then the results table contains new columns, including Standard Addition Accuracy that compares the Standard Addition Calculated Concentration for a sample to the Standard Addition Actual Concentration. Standard addition is enabled in the quantitation method on the Integration tab under the Options menu.

11/04/2021    SCIEX OS

Unable to Add Users to the Security Database in Analyst® Software

When Analyst® or SCIEX OS software is launched under the local admin account, an error message is received: “The current user is not added to the security database.” This error message appears because the software was originally installed under a non-admin account.

11/04/2021    SCIEX OS | Analyst Software

Reporter: Unable to Report Custom Columns Created in the Analyst® Software Results Table

When a user creates a custom column in an Analyst® software results table and creates a report template using a custom tag for the custom column, the data for this custom column is not output to the report. The report template will not read the custom column unless [Custom] is added to the column name in the results table

11/04/2021    Analyst Software

Custom Calculations and Flagging Rules for Carryover in SCIEX OS Software

This article contains instructions on how to set up a new processing method in SCIEX OS software that has the custom calculations and flagging rules for carryover.

11/04/2021    SCIEX OS

How Is the Full Screen Option Enabled in SCIEX OS Software?

Select the Full Screen Mode option to use SCIEX OS as the primary application. Users cannot close the software or access other software programs.

11/04/2021    SCIEX OS

Reporter Templates Cannot Be Edited Due to Missing XML Tags

When opening a template, an error was received from the Template Content Control Manager, "Error: Specified argument was out of range of valid values." To resolve this error, the Template Content Control Manager needs to be reinstalled.

How To Organize Data Using Sub-Folders in Analyst® Software

When setting up a batch in Analyst® software, a sub-folder can be created in the project's data folder to organize data by date or acquisition time. To create the sub-folder, type a backslash next to the data file name in the Data File column.

11/04/2021    Analyst Software

Chromatograms Are Randomly Missing from the Report after Upgrading Microsoft Office

When a report is created using Sciex OS, MultiQuant™, or Analyst® software, one of the chromatograms is randomly missing. This issue is due to Microsoft Office 365 Apps for Enterprise or Business being installed, and this version of Office is not currently compatible with the current versions of SCIEX software.

Multiwash Section in Analyst® Device Driver 1.3 Software Is Grayed Out when Configured with Agilent 1290 MultiSampler

The Analyst® Device Driver 1.3 software includes a Multi-wash section on the Multisampler tab when the LC portion of an Analyst software method is open, but it is grayed out. If the multi-wash hardware accessory is not installed on the autosampler, the Multi-wash screen will not be available for editing.

11/04/2021    Analyst Software

Reporter Error: Template Not in Your Trusted Location

If a reporter error shows that the template is not in the trusted location when trying to save or move a report template, then the Trusted Locations list in Word must be updated to include locations where SCIEX reports and templates are edited.

MultiQuant™ or SCIEX OS Software: The Ion Ratios on the Report and Results Table Do Not Match

When a query file is used to calculate the ion ratio calculations in a MultiQuant™ or SCIEX OS software report, the values for the internal standards ion ratios in the report output will not match those in the results table. This issue is observed when the internal standards are not assigned to the analytes in the order in which they are listed on the quantitation/processing method.

IF Statement Syntax for Calculated Columns in SCIEX OS Software 2.1.6

Reports created with SCIEX OS software use templates with embedded tags. One of the commonly used tags is the IF statement, and the basic syntax for this tag is as follows: if(<condition>;<value if true>;<value if false>)

11/04/2021    SCIEX OS

Adding or Removing Samples from the SCIEX OS Software Results Table

Open a results table in the Analytics workspace in SCIEX OS Software. Select the More menu > Add samples. In the Select Samples dialog, select the required samples.

11/04/2021    SCIEX OS

Library Hits Are Missing from the Library Search Reports in Analyst® Software

When using the library search report templates in Analyst® software, the library hits or the name of the compounds that has a library match does not show up in the report. This is due to an IF statement present in the pre-installed, standard, library-search templates that checks if the library hit is greater than zero ($Libs_Max_Hit_Count>0).

11/04/2021    Analyst Software

Adding a Syringe Pump To a Hardware Profile in Analyst® Software

Adding a syringe pump to a hardware profile in Analyst® software is necessary if the user needs to use the syringe pump to infuse sample during manual tuning. This article provides instructions on how to update a hardware profile to include a syringe pump.

11/04/2021    Analyst Software

What is the Difference Between an EMC and an EMS Scan on a QTRAP® System?

The EMS and EMC scans are two different scan types that can be run on a QTRAP® system, making use of the linear ion trap (LIT) functionality. The EMS or enhanced mass scan is a full mass range MS scan in the LIT. The EMC or enhanced multiple charge scan is carried out in the LIT, where high charge state ions are selectively trapped and scanned.

11/04/2021    QTRAP Systems

Setting Up a New Project in SCIEX OS Software

Projects can be created in the Status panel by selecting the white plus sign in a circle icon next to the projects drop down menu. Selecting the button will bring up the New Project screen where the name of the New Project will be entered. Projects can also be created in the Configuration module by selecting the Projects tab.

11/04/2021    SCIEX OS

Can Data Files Be Renamed after Acquisition Is Complete?

It's possible to change the name of a raw data file after it has been acquired in Analyst® or SCIEX OS software. Both the .wiff and .wiff.scan files would have to be named in the exact same manner or they may become corrupted.

11/04/2021    Analyst Software

SCIEX OS Software: Unable to Upload Exported Text File to Watson LIMS

In SCIEX OS software 2.1.6, if the internal standards appear in any location in the results table, instead of being grouped together at the bottom of the analyte list, and are distributed throughout the processing method, then the exported results text file cannot be uploaded to Watson LIMS.

11/04/2021    SCIEX OS

How To Create Sub-project Folders in SCIEX OS Software

Within projects, data can be further organized in sub-folders in SCIEX OS software. This article explains how to create a sub-project using the Add Data Sub-Folders dialog in the Configuration workspace.

11/04/2021    SCIEX OS

Analyst® Software: Where Are the Library Search Parameters Set?

In Analyst® software, the library search parameters such as maximum number of hits, minimum purity, hit, etc. are set in the config files that are saved under C:\Program Files (x86)\AB SCIEX\AnalystReporter\Resources\AlgorithmConfigFiles.

11/04/2021    Analyst Software

How to Export the Peak List in SCIEX OS Software

SCIEX OS software users can save the peak list for the currently active spectrum or chromatogram to a tab-delimited text file. This file contains information such as the centroid X-value (mass or time), peak area, height, etc.

11/04/2021    SCIEX OS

How to Apply Regional Settings in SCIEX OS Software

This article describes how to have the Windows regional settings (language, time/date formatting and regional preferences) match the formatting in SCIEX OS software.

11/04/2021    SCIEX OS

How Does SCIEX OS Software Calculate the Ion Ratio for a Component?

SCIEX OS software uses the regression parameter defined for the first component in the results table to calculate the ion ratio for all of the components in the results table.

11/03/2021    SCIEX OS

Saving Consecutive Batches for the Echo® MS System to the Same Data File Impairs Peak Splitting, Automatic Processing

For data acquired with the Echo® MS system, peak splitting is performed after acquisition is complete. If a subsequent batch is acquiring data to a file while the system is splitting peaks written to that file during the previous acquisition, then a resource conflict occurs.

11/03/2021    SCIEX OS | QTOF Systems

What Fields in DiscoveryQuant™ Software Standard Template Are Default Names?

In DiscoveryQuant™ software version 3.0.2 and version 3.0.2 with HotFix 2, default names are generated for the sample, acquisition method, and data file name fields if they are not defined in the imported LIMS file.

11/03/2021    DiscoveryQuant Software

Queue TIC Plot Does Not Resize Properly when the Window Size Is Adjusted in DiscoverQuant™ Software 3.0.2

The patch, DiscoveryQuant™ 3.0.2 Patch for Scrollbars and Plot Resize Issue, needs to be installed to resolve the TIC plot not resizing when using DiscoveryQuant software 3.0.2.

11/03/2021    DiscoveryQuant Software

Data File Sample Information Is Incorrect for Data acquired with Different SCIEX OS Software Versions

If data is acquired with one version of SCIEX OS software, and then data is appended to the data file (.wiff) with another version of SCIEX OS software, then the software version recorded in the data file is incorrect. The earlier software version will be shown in the File Info section, and the newer version will not be captured in the file information.

11/03/2021   

The ExionLC 2.0 System Status Icon in the Analyst®Software Is Red But Shows as Ready

Sometimes when an error occurs on the ExionLC 2.0 system, the LC status icon in the Analyst® software turns red — but the LC status may be listed as Ready. To reset the LC system, deactivate the hardware profile and then activate it again.

11/03/2021   

Differences in Date-Time Stamp for a Results Table Audit Map in Analyst® Software

In the Audit Trail Manager in Analyst® software, the audit map associated with a Results Table (accessed under the Results Tables node) might have a modified date-time that is different than the modified date-time shown with the project node (accessed under the Projects node) or in a Windows folder.

11/03/2021    Analyst Software

Why Does Activating the Hardware Profile in Analyst® Software Change the Date of the Instrument Data File?

For SCIEX Triple Quad™ and QTRAP® Systems, the Analyst® software creates backup instrument data parameter setting files when deactivating a hardware profile. Each time the hardware profile is activated, it loads the correct backup file according to the mode of the default instrument data and parameter setting files; because the file is changed, the date on the instrument data file also changes.

11/03/2021    Analyst Software

Is SCIEX OS Software Compatible with Cliquid® Software?

No, SCIEX OS software cannot coexist with the Cliquid® software on the same PC.

11/03/2021    Cliquid Software

Location of the Analyst® Software Configuration Files

The configuration files contain the processing parameters for library searching in Analyst® software. These parameters can be changed under the ConfirmationLibrarySearch.config or MultipleCandidateLibrarySearch.config files, and these files are typically saved under C:\Program Files (x86)\AB SCIEX\AnalystReporter\Resources\AlgorithmConfigFiles.

11/03/2021    Analyst Software

What is the Limit of the Path Length for the SCIEX OS Software Installer to Ensure a Successful Install?

The SCIEX OS software installation folder path is limited to 118 characters or less.

11/03/2021    SCIEX OS

Is the Shimadzu LC-40 Fluorescence Detector RF-20AXS Supported in Analyst® Software?

Yes, Analyst® software 1.7.2 can directly control the Shimadzu Nexera LC-40 fluorescence detector RF-20AXS.

11/03/2021    Analyst Software

Which Version of DiscoveryQuant™ Software Supports the Acquity LC on Windows 10?

The Windows 10 compatible version of DiscoveryQuant™ software that supports Acquity LC is version 3.0.1 Hotfix 2.

11/03/2021    DiscoveryQuant Software

Can SCIEX OS Software Be Installed on a PC with Windows 10 Hotfix2?

No, SCIEX OS software cannot be installed on a PC with Windows 10 hotfix2.

11/03/2021    Software

Can Analyst® Software Directly Control the Shimadzu SPD-M40 Detector?

Analyst® software 1.7.2 can directly control the Shimadzu SPD-M40 detector through the Shimadzu MIMIC 2 driver that has been incorporated into Analyst software.

11/03/2021    Analyst Software

What is the Maximum Length of the Project Path in Analyst® Software to Submit a Batch Successfully?

In Analyst® software 1.7.2, users cannot save or submit an acquisition batch if the name of the project path is longer than 126 characters.

11/03/2021    Analyst Software

Delete Rights Are Not Needed to Save or Overwrite a PDF Report in Analyst® Software 1.7.2

In Analyst® software 1.7.2, delete rights are not needed to save or overwrite a PDF file to the folder where the original PDF report is saved.

11/03/2021    Analyst Software

Configuring a SCIEX X500 QTOF System after Downgrading SCIEX OS Software 2.0 to 1.7

After re-installing SCIEX OS software 1.7, stop the ClearCore2 service and then install the Microsoft C++ Redistributable package (vc_redis*.exe) from the install folder in the SCIEX OS 2.0 installation package. This will enable user to configure an SCIEX X500 QTOF System in the Devices workspace.

11/03/2021    SCIEX OS

Unable to See Chromatograms when a MultiQuant™ Software Report is Printed

If the Peak Fill option is set to "Do Not Fill Peaks" in MultiQuant software, chromatograms will be faded out when output to a report and sometimes appear as not legible.

11/03/2021    MultiQuant Software

Why Is No Data Acquired in EAD Fragmentation Mode on a ZenoTOF 7600 System?

If EAD fragmentation is used in an acquisition method on a ZenoTOF 7600 system, then the accumulation time must be at least three times the reaction time. If it is not, then no data will be acquired. To resolve the issue, increase the accumulation time in the method in SCIEX OS software.

11/03/2021    SCIEX OS

Why Does the SCIEX OS Software 2.1.6 Installer Disable the System Restore Task?

The SCIEX OS software 2.1.6 installer disables the System Restore task for better performance of the application.

11/03/2021    Software

When Do I Click the Confirm Button in SCIEX OS Software during Watson LIMS Data Transfer?

When transferring data to Watson LIMS from SCIEX OS software, the user must wait for the transfer to complete successfully before clicking Confirm in SCIEX OS software. It the user clicks Confirm before the transfer is complete, then the transfer status will show as failed.

11/03/2021    SCIEX OS

Status Display Issue for ExionLC 2.0 Systems with UV/Vis Detectors in Analyst® Software

If an Exion LC 2.0 system contains a DAD or multiwavelength detector, then after the LC system and mass spectrometer go to Standby state, the Analyst® software status icon for the ExionLC 2.0 system turns yellow, but the LC system state is shown as Wait.

11/03/2021    Analyst Software

Is Installing a SCIEX Software Hotfix on an Unsupported Instrument Problematic?

There are no negative effects caused to software or instruments by installing SCIEX software hotfixes on an instrument model not expressly covered by the hotfix (as indicated in the release notes).

11/03/2021    Analyst Software

What Should I Do if the Scrollbars Are Missing in DiscoveryQuant™ Software 3.0.2 Hotfix2?

When working with DiscoveryQuant™ software 3.0.2, the scrollbars are missing, making it difficult to view the data. This issue can be resolved by installing the patch, DiscoveryQuant 3.0.2 Patch for Scrollbars and Plot Resize issue.

11/03/2021   

Can I Do Any Data Processing in Keystone™ Viewer Software?

No, Keystone™ viewer software provides data viewing capabilities only.

11/02/2021    Software

What SCIEX Mass Spectrometer Data Files Work with Keystone Converter Software?

Keystone Converter Software can convert nominal mass (.wiff1) files, but it does not work with SCIEX OS software files or TripleTOF system files.

11/02/2021    Software

Does SCIEX OS Software Have Functionality To Help My lab Achieve Compliance with Regulations?

Yes. SCIEX OS software has all the key data integrity features required to reduce your regulatory risk, including configurable security, electronic signatures, and audit trails.

11/02/2021    SCIEX OS

Will Keystone™ Viewer Software Open Any AnIML file, or Just ANIML files Converted by Keystone Converter Software?

Keystone™ viewer software displays an AnIML file, including those that were not created by Keystone converter software.

11/02/2021    Software

How Does the Size of a Converted AnIML File Compare to the Original Wiff File Size?

The converted AnIML file created using the Keystone™ converter software is 1.6 to 1.8 times bigger for data sets with multiple reaction monitoring (MRM) data. This is because the original .wiff.scan file is compressed, but then it is uncompressed as part of the conversion and storage process when creating the AnIML file.

11/02/2021    Software

What is the Source of the Atomic Weight Information in BPV Flex Software?

BPV Flex software uses the same source of atomic weight information as BioPharmaView™ software. The theoretical value required for the intact workflow uses the average molecular weight; the peptide workflow uses the monoisotopic weight.

Can a LIMS System Be Connected Directly to SCIEX OS Software?

Yes, SCIEX OS software supports the ability to send results directly to Watson LIMS. Other LIMS connections are possible through a third-party provider, Data Innovations.

11/02/2021    SCIEX OS

Users Are Unable to Save or Submit Batches with Long File Paths in Analyst® Software 1.7.2

In Analyst® software 1.7.2, users cannot save or submit an acquisition batch if the project path is longer than 126 characters.

11/02/2021    Analyst Software

Does a POET Error Reflect a Possible Network Connectivity Error or an Unsupported Network Drive Type?

This article describes what to do to identify this POET error in more detail. A POET error can arise when saving a results table in Analyst® software, with the error typically arising when saving the results table file to a network drive.

11/02/2021    Analyst Software

Is There a "Batch-Convert" Function Available in Keystone™ Converter Software?

Yes, Keystone™ converter software offers a command line option to allow for the creation of automated processes for converting large pools of legacy data.

11/02/2021    Software

Can an Analyst® Software Results Table Be Opened in SCIEX OS Software?

No, an Analyst® software results table cannot be opened in SCIEX OS software. The user will have to recreate the Analyst results table in SCIEX OS software.

11/02/2021    SCIEX OS | Analyst Software

How Do I Install the Intact Protein Script on the TripleTOF® 5600 and 6600 Systems?

The Intact Protein script can be installed from the Analyst® TF software directory located at: C:\Program Files (x86)\Analyst\Scripts. The ShowInTuneLayout script must be installed and enabled in order to acquire intact proteins.

11/02/2021    Academia Omics | Pharma CRO

How to Simulate a Hardware Profile with a Mass Spectrometer and Shimadzu LC in Analyst® Software

In Analyst® software, creating a simulated hardware profile allows a user to create acquisition methods and batches when using the software on a processing PC that is not connected to an instrument. To create a simulated hardware profile, open the Hardware Configuration Editor and select a hardware profile that you would like to simulate. Then select Edit Profile.

11/02/2021    Analyst Software

Can ProteinPilot™ Software Version 5.0.2 Be Installed on a 2019 Server?

Yes, ProteinPilot™ software 5.0.2 can be run on a Windows 2019 Server. This was not officially tested or mentioned in the release notes, but many users have installed the Windows 10-compatible ProteinPilot software 5.0.2 on the Windows Server 2019 operating system and have run the software successfully in this environment.

What Type of Analyst® Software Data Is Used with Keystone™ Converter Software?

Keystone™ converter software will convert nominal mass .wiff1 files from Analyst® software 1.4.1 and later versions.

11/02/2021    Analyst Software

Magnifying Chromatogram Peaks Displayed in a SCIEX OS or MultiQuant™ Software Report

The chromatograms of peaks that are displayed in a report generated in SCIEX OS or MultiQuant™ software will retain the format of the original peaks displayed in the peak review pane. To magnify the peaks displayed in a report, the zoom settings will need to be changed in the peak review settings for MultiQuant or SCIEX OS software.

11/02/2021    SCIEX OS | MultiQuant Software

What Is the Peak Split Algorithm when Using a Marker Peak with the Echo® MS System?

The marker well in the Echo® MS System is defined by the user in the acquisition batch to generate a special barcode pattern at the beginning and end of the plate run. The barcode is a pattern composed of a narrow peak, then a pause, a wide peak, then a pause, followed by a narrow peak.

11/02/2021    SCIEX OS

What Information Is in the AnIML File Created by the Keystone™ Converter Software?

AnIML, an open standard XML data format for storage and sharing of experimental data, is the file format that is created when a data file is converted by the Keystone™ converter software. This article details the information that is included in the converted AnIML file.

11/02/2021    Software

Where Can I Download Skyline Unplugged for a Windows 10 64-bit PC?

Link is provided and installations instructions are described

How Do I Display the Calibration Peak List in Analyst® Software?

This article describes how to apply the appropriate calibration peak list reference table during a tuning procedure in Analyst® software.

11/02/2021    Analyst Software

What Version of Analyst® Software Is Required to Run Keystone™ Converter Software?

Keystone™ converter software requires Analyst® software 1.7.2 along with a patch for the Keystone Converter software to be installed on the data-converting PC.

11/02/2021   

How Can I Create a Custom Enzyme in BioPharmaView™ 3.x Software?

This article describes how to use a different DataDictionary file to add a custom enzyme to BioPharmaView™ software. The BioPharmaView.Data dictionary file cannot be modified. This will result in a reinstall of the software.

Can Wiff1 Files Generated by SCIEX OS Software 2.1 from X500 Series Instruments be Searched with ProteinPilot™ Software?

X500 series instruments generate wiff2 file formats, but with the newest version of SCIEX OS Software 2.1, they can also generate a .wiff1 file. Only .wiff1 files can be used to perform a ProteinPilot™ software search.

Why Are My Run Times Longer after Upgrading to MPX Software 2.0?

Run times may be longer after upgrading to MPX software 2.0 because the acquisition methods may be different for the two streams. Make sure that the methods for both streams are the same.

11/02/2021    MPX Software

How Are Peptides Named in BPV Flex Software after in Silico Digestion?

The general rule for naming peptides in BPV Flex software is: the first peptide resulting from a proteolytic cleavage is named T1 for sequences displayed from the N-terminus to the C-terminus; moving toward the C-terminus, the second proteolytic cleaved peptide is named T2, and so forth.

11/01/2021    Academia Omics | Pharma CRO | Software

How to Interface MultiQuant™ Software with a LIMS System via a LIMS Report Template

Oftentimes MultiQuant™ software results table data needs to be exported and then interfaced with a LIMS system. This article explains how to indirectly transfer data from results tables created in MultiQuant software to a LIMS system via a report template. The report template creates an output file in CSV format that can then be interfaced with a LIMS system.

11/01/2021    Clinical | Mass Spectrometers

Can I Submit mzIdentML Files from ProteinPilot™ Software 5.x to the PRIDE Repository?

This article summarizes the issues with ProteinPilot version 5.0 and mzIdentML created files. Submission of mzIdentML files is still not automated with later versions of ProteinPilot™ software, including version 5.0.x. Complete submissions from ProteinPilot software to PRIDE are not possible, but partial submissions of the mzIdentML are, and this partial submission process is described below.

How Is the New SCIEX OS Software Quantification Algorithm Better than the Original Analyst® Software Classic Algorithm?

The quantification algorithms for finding and integrating peaks in SCIEX software programs have improved significantly since the Analyst® software classic algorithm was introduced. Users of the SCIEX OS software will see two main advantages when integrating peaks with the new AutoPeak algorithm.

10/07/2021    SCIEX OS | Analyst Software

What Are the Advantages of the .wiff2 Data File Format?

The .wiff2 meta data file generated by SCIEX OS software is designed to offer users improved security for their data. One of the primary advantages is the .wiff2 meta data file is encrypted, which prevents software users from tampering with results.

10/06/2021   

What Is the Difference Between .wiff and .wiff2 Data Files?

There are two data file formats for data sets acquired using SCIEX mass spectrometers: 1) .wiff and 2) .wiff2. Instruments using Analyst® software to acquire data will write data sets in the .wiff format. Instruments acquiring data using SCIEX OS software (version 2.0 or lower) will write data sets in the .wiff2 format. The newer versions of SCIEX OS software (version 2.1 and greater) write data in both the .wiff and .wiff2 format.

10/05/2021   

How to Use the MAM Script in BioPharmaView™ Software 3.0.2 to Transfer Peptide Information to SCIEX OS Software

BioPharmaView™ software 3.0.2 has improved its multiple attributes monitoring (MAM) workflow, and the software now includes a script, MAM-BPV to Analytics Converter, used to create a quantitative processing method for the Analytics mode of SCIEX OS software.

Top 10 Things Users Can Do to Minimize Contamination of LC/MS Systems

Several things can be done to reduce the contamination of LC/MS systems that require minimal time but increase uptime and robustness. Here, we present a list (in no particular ranking) of the top ten things to consider when trying to lower instrument contamination.

05/21/2021   

How to Display High-Precision m/z Values in LibraryView™ Software

Select and open a compound in LibraryView™ Software. Then navigate to the MS/MS Spectra tab to view any MS/MS spectra for the compound. Select the ‘i’ button in spectrum panel, and a peak list with high precision m/z values will be displayed.

04/05/2021   

How Is the Peptide Score Calculated in BPV Flex™ Software 2.1?

The BPV Flex™ Software 2.1 peptide score indicates the probability that the peaks in a given MS/MS spectrum will match those of the theoretical peptide fragments by random chance. Therefore, the score calculation is derived from observed MS/MS fragments and the corresponding intensities, as well as the number of theoretical MS/MS fragments.

Location of the Current Instrument Data File for SCIEX Triple Quad™ or QTRAP® LC-MS/MS 7500 Systems

The current instrument data file (current.dat file) for Triple Quad™ or QTRAP® LC-MS/MS 7500 Systems is backed up to a SCIEX OS Software folder located at C:\ProgramData\SCIEX\MassSpec\InstrumentData\YYYYMMDDHHMMSS.

Can the Existing Ion Source on the X500R QTOF System Be Converted to APCI?

The source on the X500R QTOF System can be used in atmospheric-pressure chemical ionization (APCI) mode, but a different probe with a twin electrode must be installed. In addition, a different APCI tuning solution must be used and is available for purchase from SCIEX.

Can the Existing Ion Source on the X500R QTOF System Be Converted to APCI?

The source on the X500R QTOF System can be used in atmospheric-pressure chemical ionization (APCI) mode, but a different probe with a twin electrode must be installed. In addition, a different APCI tuning solution must be used and is available for purchase from SCIEX.

Reporting Values for Calculated Concentration that Are Not Equal to N/A from a Results Table

To filter results table data in a report based on the calculated concentration not equal to N/A, add the if statement $Calculated_Concentration<>"N/A".

Creating Reports where Internal Standard Peaks Appear Normalized to the Analyte Peak in Chromatograms

When viewing an analyte's chromatogram in a report, the internal standard peak that is overlaid with the analyte's is not normalized in the report's chromatogram and part of the peak appears out-of-bounds in the peak review image. If you see an internal standard peak in the peak review pane of MultiQuant™ Software or SCIEX OS Software that is not normalized to the analyte's peak size, double click on the x-axis of that particular chromatogram.

12/04/2020    SCIEX OS | MultiQuant Software

I am seeing inconsistent HPLC Peak shape. What may be the cause of this?

Summary of potential causes of poor HPLC peak shape

12/04/2020   

Displaying Analytes Horizontally and Samples Vertically on a Report

To create a report where the analytes appear horizontally (as column headers) and sample names appear vertically (at the start of a row) in a report, the For Each Analyte tag will need to be nested within the For Each Sample tag.

I am having trouble reaching temperature in the ALS Thermostat. What is the effective range of the ACMP Peltier?

The ACMP Peltier effectivity is based on the ambient temperature of the instrument. The operational range of the ACMP is between 4-40C.

12/04/2020   

Error Code 50 Appears when Creating Reports in MultiQuant™ Software

When creating reports in MultiQuant™ Software, an error appears, "Error code 50." This error is due to a corrupt file in the project folder, and a new project will need to be created.

12/04/2020    MultiQuant Software

Are PPGs Used for Tuning and Calibrating the QTRAP® or TripleQuad™ LC-MS/MS 7500 Systems?

No, a new calibrant, the MS Tuning Solution, was introduced for tuning and calibrating the QTRAP® or TripleQuad™ LC-MS/MS 7500 Systems.

12/04/2020   

Analyst® Software: How to Increase the Number of Waiting Samples in the Queue

By default the number of samples that can be submitted from the Analyst® Software queue is 100 samples. To change the number of waiting samples shown in the queue, select the Configure mode, and then navigate to the Tools menu. Select Settings and then Queue Options. Type in a desired number for Max Num Waiting Samples, and then click OK.

12/02/2020    Analyst Software

Can Multiple Users Log In to Windows while Analyst® MD Software Is Acquiring Data?

If a user starts a batch using Analyst® MD Software and then signs out of their Windows account while Analyst Software is acquiring data, the software will close and suspend the run. It is not recommended to sign out of a user's Windows account if Analyst MD Software is acquiring data.

12/02/2020    Clinical | Analyst Software

Using an Older Version to Open a Processing Method Created in a Newer Version of SCIEX OS Software

The files created in SCIEX OS Software are not backwards compatible with other versions of the software. An error will appear when a processing method created with a higher version of SCIEX OS Software (e.g., 2.0) is opened with a previous version of SCIEX OS Software (e.g., 1.7). To open a processing method created in the latest version of SCIEX OS Software with the older version, export the processing method as a text file.

12/02/2020    SCIEX OS

How Is Relative Retention Time Calculated?

For analytes using an internal standard, the actual retention time (RT) of the internal standard peak (for the corresponding sample) is first determined. The expected RT for the analyte is determined by multiplying the specified expected RT by the ratio of the actual to the expected RT for the internal standard.

12/02/2020    MultiQuant Software

Where Is the Executable File for Excel Saved on My Computer?

The executable file for Excel – Excel.exe – is located in the installation directory for the 64-bit version of Microsoft Office 365 at C:\Program Files\Microsoft Office\root\Office16. 

12/02/2020    SCIEX OS | MultiQuant Software

How to Sum the Concentrations of Isomers in SCIEX OS Software

To add the concentrations of different isomers together when processing data in SCIEX OS Software, open a processing method in the Analytics mode of the software. Select the Calculated Columns tab in the processing method and then select Add Formula to create a custom calculation for adding the isomers.  

12/02/2020    SCIEX OS

How to Open a Reporter Query Used with SCIEX OS or MultiQuant Software Report Templates

This article discusses the three ways to open a query (a file with the extension .query), a file linked to a report template that can be used to perform more complicated calculations or sorting functions in a results table.

When Should I Use Retrieve Configuration in Analyst® Device Driver Configure Mode?

In Analyst® Device Driver, when adding or changing a CTC PAL3 autosampler configuration, the Retrieve Configuration command must be performed in the Configure mode in the CTC PAL3 LC sampler dialog.

11/10/2020    Analyst Software

What Value Should Be Used for the XIC Width in My SWATH® Acquisition MicroApp Processing Settings?

One common error when using the SWATH® Acquisition MicroApp 2.0.1 for processing SWATH data is to relate the XIC width setting in the processing software with the mass accuracy of the instrument, and set the XIC width to a value that is too low. XIC extraction widths should be set to 50 to 75 ppm, regardless of the mass accuracy of the acquired data.

Connecting to a New Compound Database Library in Analyst® Software

The steps needed to connect to a new compound database library in Analyst® Software are detailed in this article.

11/10/2020    Analyst Software

Unable to Open SCIEX Cloud ProteinPilot™ Software Searches with the Desktop Version 5.0.2

The version of ProteinPilot™ Software in the SCIEX Cloud is version 5.0.3; therefore, group files created in the SCIEX Cloud cannot be downloaded to a desktop and opened in ProteinPilot Software 5.0.2. To download and read a group file on a desktop installation of ProteinPilot Software, the desktop version must be upgraded to version 5.0.3.

Can I Use Windows Experience Enhancers on My SCIEX Acquisition and Processing PCs?

Some PC users prefer different views and/or functionalities in the new Windows 10 interface. There are freeware/shareware programs available that allow for the customization of Windows features (such as emulation of Windows Classic settings). However, these types of Windows accessory programs have not been tested with SCIEX software; their use is not supported.

11/10/2020   

MasterView™ Software Report Error: Object Reference Not Set to an Instance of an Object

When creating are report in the PeakView®/MasterView™ Software suite, the following error appears: "Object reference not set to an instance of an object." This error occurred because a file other than a report template was selected during the create report process.

11/10/2020    MasterView Software

Why Do the Results for Some Analytes Shift to a New Column in a CSV Report?

When reporting results table values to a comma-separated values (CSV) report, for some analytes, the reported information is shifted from the correct column to one column over to the left. This column-shifting issue is observed when an analyte name contains a comma.

Which Glycan Notation Is Used in the BioPharmaView™ Software?

The glycan notation used in BioPharmaView™ Software is the Oxford style.

Where Is the License File Saved to Activate a SCIEX Library Used with SCIEX OS Software?

For libraries imported into SCIEX OS Software and used with LibraryView 1.x Software, the license file needs to be saved to the directory C:\Program Files\AB SCIEX\LibraryView\LibraryViewFramework\Server in order to unlock the library and activate it.

11/10/2020    LibraryView Software

Remote Data Access Software Error on MALDI TOF/TOF™ instruments

When setting up ProteinPilot™ Software or the imaging acquisition software for the MALDI TOF/TOF™ Systems, a RDA (Remote Data Access) software error message is received: "TOF/TOF Imaging Acquisition Software. The client components used to communicate with the instrument are newer than those found on the instrument. Please update the Remote Data Access service on the instrument."

11/09/2020    Academia Omics | Pharma CRO

Is the Digital PicoView® Ion Source Compatible with Analyst® TF Software 1.8.x?

Both Analyst® TF Software 1.8.x and the software for the Digital PicoView® Nanospray Ion Source will work together with the Windows 10 operating system. This was tested and confirmed separately by both manufacturers, SCIEX and New Objective. 

11/09/2020    Analyst Software

What File Formats Can Be Converted with the Newest Version of ProteoWizard Software?

This newest version of ProteoWizard software, version 3.0.20258-97f41f698, can now convert files to the txt format, as well as the three original file types (MGF, mzML and mzXML). For SCIEX software users, the txt file might be a useful option; however, the quality of the output file from ProteoWizard has not tested.

11/06/2020    Academia Omics

Filtering Audit Trail Events Using a Set of Specified Criteria in SCIEX OS Software

The audited events in the audit trail can be filtered using a set of specified criteria in SCIEX OS Software by selecting the Filter icon in the upper task bar on the Audit Trail screen.

11/06/2020    SCIEX OS

ProteinPilot™ Search Error: Unhandled Exception: Out Of Memory Exception

During a search with ProteinPilot™ Software 5.0, 5.0.1 and 5.0.3, the error "Unhandled Exception: Out Of Memory Exception" appears. This issue is due to the LC/MS reconstruct crashing within the ProteinPilot Software when data sets with a high MS1 scan speed are being processed.

Is the E Lens™ Technology Used in the OptiFlow® Pro Ion Source Compatible with Atmospheric Pressure Chemical Ionization??

No, the E Lens™ Technology integrated into the SCIEX Triple Quad™ 7500 LC-MS/MS System has been designed for electrospray ionization (ESI) mode of analysis and is not compatible with atmospheric pressure chemical ionization (APCI).

11/06/2020   

How Inclusion or Exclusion Lists Are Imported into Analyst® TF Software

This article describes how a text file can be created to import an inclusion or exclusion list into Analyst® TF software when building an IDA method.

11/06/2020    Pharma CRO | Analyst Software

Can the Probes and Electrodes for the OptiFlow® Ion Source Be Used with the OptiFlow Pro Ion Source?

The probes and electrodes for the OptiFlow® Ion Source can be used with the OptiFlow Pro Ion Source.

11/06/2020    QTRAP Systems | Triple Quad Systems

Can I Use My Own Calibrant Solution to Tune the QTRAP® or TripleQuad™ LC-MS/MS 7500 System?

To tune and calibrate a SCIEX QTRAP® or TripleQuad™  LC-MS/MS 7500 system, a new calibrant, called the MS Tuning Solution, was recently introduced and must be used to tune the new instrument.

11/06/2020   

How Can Audit Trail Records Be Viewed from SCIEX OS Software?

To view audit trail records in Sciex OS Software, open the Audit Trail workspace. The Audit Trial screen will appear. Select Workstation in the left pane to view the audit trail for the workstation. Select Project in the left pane to view the audit trail for the project of interest.

11/06/2020    SCIEX OS

Does SCIEX OS Software Offer Tools To Assist with Achieving 21 CFR Part 11 Compliance?

The features within SCIEX OS software that help users achieve 21 CFR Part 11 compliance are explored in the article, "SCIEX OS LC/MS Software and 21 CFR Part 11 Regulations".

11/06/2020   

Can the SCIEX QTRAP® or TripleQuad™ 7500 LC-MS/MS System Operate without E Lens™ Technology Active?

Yes, the SCIEX QTRAP® or TripleQuad™ 7500 LC-MS/MS Systems can operate without the E Lens™ Technology active. Each QTRAP and TripleQuad 7500 System comes with a blanking plug that can be inserted should there be a need to operate without the E Lens Technology.

11/06/2020    QTRAP Systems | Triple Quad Systems

Are the Ion Sources Interchangeable Between the QTRAP® and TripleQuad™ 6500+ and 7500 Systems?

The ion sources for the SCIEX QTRAP® and TripleQuad™ 6500+ and 7500 LC-MS/MS Systems are not interchangeable. The OptiFlow® Pro Ion Source cannot be used on the QTRAP or TripleQuad 6500+ Systems. Likewise, the IonDrive™ Turbo V, Turbo V™, and OptiFlow Ion Sources cannot be used with the QTRAP and TripleQuad 7500 Systems. 

11/06/2020    QTRAP Systems | Triple Quad Systems

Creating a ProteinPilot Software Winner Proteins Results List as FASTA File

This article describes the steps for creating a FASTA file from a ProteinPilot™ software report of winner proteins.

Electronically Resetting the X-series QTOF MS Systems (X500R and X500B)

The steps required to reset the X-series QTOF MS Systems (X500R and X500B) are described here.

11/06/2020   

Flags or Custom Results Are Not Showing Correctly on a SCIEX OS Software Report

A mismatch of index can occur when internal standard values from a SCIEX OS software results table are processed within a query, causing the text for the reported values to appear bolded and in red, even when there is no reason for flagging these values in the report itself. This phenomena is observed for results tables created in versions of SCIEX OS Software 1.6.1 or lower and has been fixed in versions of SCIEX OS software 1.7 or greater.

11/06/2020    SCIEX OS

What Is the Part Number for the Solvent Guides Used in the Amplifex™ Diene Reagent Kit?

This article provides the part number for the solvent guides used in the Amplifex™ Diene Reagent Kit.

11/06/2020    Amplifex Keto Reagent

How to Print an Acquisition Method in Analyst® Software

To print an acquisition method in Analyst® software directly from the .wiff file, open data file under the Explore mode and then click on the i icon in the toolbar for the data file's information. Activate the file info pane by selecting it, and then go to File > Print > Pane.

11/05/2020    Analyst Software

Is There an Equivalent to Single User Mode in SCIEX OS Software 2.0?

Single user mode is a security mode in Analyst® software that allows for any user that is logged in to a PC using any Windows account to access the software as an administrator. However, there is not currently an equivalent to single user mode in the SCIEX OS software. The security mode options in SCIEX OS software are limited to integrated mode and mixed mode.

11/05/2020    SCIEX OS | Analyst Software

How to Set the Parameter Settings in Analyst® Software Back to Original Factory Settings

The parameters settings in Analyst® software can be set back to the original, default factory settings by selecting the Parameter Settings option from the Tools menu and then using the Factory Settings button to reset the parameters of the selected scan type.

11/05/2020    Analyst Software

How to Remove the Extra Characters from an Analyte Name in a Report

To report the analyte name in a report without additional characters showing after the name, use the TRIM and LEN functions in the expression written in the Math Field Type tag in the report template.

11/05/2020    SCIEX OS | MultiQuant Software

Controlled Ways to Output Data from SCIEX OS Software

The controlled ways to output data from the SCIEX OS software Analytics workspace include 1) exporting a results table; 2) Transferring  the results table data to a LIMS; and 3) Creating a report though the Reporting tab option Create Report and Save Results Table.

11/05/2020    SCIEX OS

Adding a Flag or a Custom Flag Created in SCIEX OS Software to a Report

After creating a new results table in SCIEX OS software, add the Outlier Reasons column in the quantitation method to the Input tab of a query. Then, in the AnalystCalculations tab of the query, use the search function to find the flag of interest. Have the Outlier Reasons column added to the query's Output tab, and then link the Outlier Reasons column to the report template using a custom tag.

11/05/2020    SCIEX OS

How to Apply an External Calibration Curve to a Results Table in MultiQuant™ Software

In MultiQuant™ software, a previously-created calibration curve can be imported into a results table and applied to the existing unknown samples. In the old results table with the calibration curve that you would like to export, ensure the standard samples are present and select the Process menu. Then select Export Calibration, name the calibration curve data, and click Save.

11/05/2020    MultiQuant Software

Where Are the Files Containing the Hardware Profiles Stored in Analyst® Software?

The hardware profiles created in Analyst® software are stored in the API Instrument project folder in the Configuration sub-directory: C:\Analyst Data\Projects\API Instrument\Configuration.

10/30/2020    Analyst Software

Recovering a Lost or Corrupted Acquisition Method in Analyst™ Software

To recover or recreate an acquisition method that was lost or corrupted in Analyst™ Software, click in the information pane of an older data file, and then right click and choose Save Acquisition Method.

10/30/2020    Analyst Software

To configure Data Innovations' instrument manager system with the SCIEX LIMS transfer license, SCIEX software users must contact Data Innovations, not SCIEX, for assistance with the data transfer setup. Users who purchased the LIMS license for SCIEX OS or MultiQuant™ software will need to reach out to Data Innovations directly by emailing your region’s specific sales group. This will allow Data Innovations to track your request and provide a response within 48 hr.

10/30/2020   

What Is a Regular Expression?

A regular expression (regex), also called a rational expression, is a sequence of alphanumeric and/or special characters that can define a search pattern depending on their context.

10/30/2020   

How to Improve SCIEX OS Software Performance during Data Analysis

SCIEX OS software may perform slowly during data analysis due to the location of the data files being processed. Relocating data files from a temporary location (such as the Windows desktop) to a SCIEX OS or Analyst software project folder that is located in the root directory mapped in the Configuration module of SCIEX OS software may improve the software performance. 

10/30/2020    Software

Watson LIMS Needs To Be in Compatibility Mode for Use with SCIEX OS Software

When transferring data from SCIEX OS software to Watson LIMS, the Watson software did not appear to be importing the data.

10/30/2020    SCIEX OS

Does the Echo MS System Support All QTRAP® 6500+ System Functionality?

The Echo® MS System cannot be supported by the QTRAP® 6500+ System; instead, Echo MS is paired with the TripleQuad 6500+ System for data acquisition.

10/30/2020   

Where Are the Event Logs for SCIEX OS Software Archived?

When event logs in SCIEX OS software become too large, the software will create an archive event log file. This file is located in the directory C:\ProgramData\SCIEX\Clearcore2.Acquisition.

10/30/2020    SCIEX OS

Initiate Transfer to Watson LIMS in SCIEX OS Software Prevents Analyst® Software from Launching

When the feature Initiate Transfer to Watson LIMS is selected in SCIEX OS software, software users find that the Analyst® software installed on the same workstation will no longer launch. This is the expected behavior for Analyst software and depends on the configuration and the installation order of other SCIEX software that were installed on the same PC. 

10/30/2020    SCIEX OS | Analyst Software

Adding Custom Columns to a SCIEX OS Software Report Template

In SCIEX OS software, a custom column added to a results table can be included in a report template with a custom tag.

10/30/2020    SCIEX OS

Where Can I Find My Hardware Profile in SCIEX OS Software?

The hardware profiles for instruments supported by SCIEX OS software are stored in a file called HardwareProfile.hwp that is located in the following directory: C:\ProgramData\SCIEX\Clearcore2.Acquisition.

10/30/2020    SCIEX OS

Adding Custom Columns to a Results Table in Analyst™ Software

To add custom columns to a results table in Analyst™ software, right click within an open results table and select the option Add Custom Column.

10/30/2020    Analyst Software

Is There a Password Character Limit for Accessing Analyst® Software in Mixed Mode?

Passwords used to access Analyst® software in mixed mode are capped at 13 characters. If your internal IT policy for the Windows password specifies more characters, this longer password requirement may lock the user out of Analyst software in mixed mode.

10/30/2020    Analyst Software

Where is the SCIEX OS Software Security Database Found?

The SCIEX OS software security database files are located at C:\ProgramData\SCIEX\Clearcore2.Acquisition, and the file is called Security.data.

10/30/2020    SCIEX OS

Can I Change the Sorting Order for Project Folders in Analyst® Software?

Analyst® software does not have not have internal sorting logic, so to sort projects, the API functions, FindFirstFile and FindNextFile, are used to retrieve the files from the directory. The order in which the file names are returned is dependent on file system type (NTFS, CDFS or FAT).

10/30/2020    Analyst Software

Adding an Arrow in MultiQuant™ Software to Display the Expected Retention Time during Peak Review

In MultiQuant™ software, an arrow can be added to the peak review chromatogram window to represent the expected retention time. To do this, right click within the peak review pane and select Options from the list. A Peak Review Options popup window will appear. Check the option Mark Expected RT with Arrow under the Appearance tab. Then select OK. 

10/29/2020    MultiQuant Software

Turning the Checksum Option On or Off in Analyst® Software

In order to turn the checksum option on in Analyst® software, select the View menu and then choose Audit Trail Manager.

10/29/2020    Analyst Software

Reporter: Why Did the Outlier Reasons Column Change Color after Running a MultiQuant™ Software Query?

The text in the outlier reasons column will change from black to pink if the column value exceeds the cutoff value in  MultiQuant™ software. If a query is run after creating the MultiQuant software results table, the flagging color of the query overrides the flagging color of the outlier reasons column in the results table.

10/29/2020    MultiQuant Software

How to Export a Statistics Table From SCIEX OS Software to Excel

The statistics pane can be accessed from the Views menu in the Analytics module of SCIEX OS software. After opening the results table, select Statistics pane from the Views menu and a new table appears below the results table. To export the contents of the statistics table from SCIEX OS, the table can be copied to Excel by highlighting all rows, and then selecting Ctrl+C. In an open Excel spreadsheet, the selected columns and rows can be pasted using Ctrl+V.

10/29/2020    SCIEX OS

Restoring Icons to the Analyst® Software Toolbar

To restore missing toolbars in Analyst® software, select the Tools menu, and then select the Restore Default Toolbars option. This should restore the icons that were not showing previously. 

10/29/2020    Analyst Software

Resolving the Analyst® Software 1.7 Error: Feature Has Expired

The licensing error, Feature has expired, appears when Analyst® software 1.7 is launched. This article explains how to replace the license file to resolve the error.

10/28/2020   

Differences between iTRAQ® Reagents Application Kit - Protein (4374321) and iTRAQ® Reagent 4Plex or 8Plex Kits

This article describes the different workflows for the iTRAQ® Reagents Application Kit - Protein (4374321) and the iTRAQ Reagents - 4plex or 8plex kits.

10/22/2020    Academia Omics | Pharma CRO | iTRAQ Reagent

Incorrect Argument Error when Adding Standards to a Results Table in SCIEX OS Software

When adding multiple standard samples with the same name to a results table in SCIEX OS software, an error was generated: "Incorrect Argument. An item with the same key has already been added." This article explains the workflow that generates this error and provides a workaround.

10/22/2020    SCIEX OS

Why Do I Receive Memory Concerns Warning when Processing Data in MultiQuant™ Software?

When processing a large data set in MultiQuant™ software 3.0.3, users may see a Memory Concerns message, "The Results Table you opened may cause out of memory computer issues. To free-up memory close other applications and any other opened results table." This message is a warning, not an error message, regarding the amount of memory required to process and display a large data set.

10/22/2020   

Differences between “Find Any” and “Find” in FormulaFinder in SCIEX OS Software

In SCIEX OS software, the “Find Any” function in Formula Finder considers just the monoisotopic peak to be within the m/z tolerance. Both odd (in italics) and even electron elemental compositions are provided. When using “Find Any” element ranges “From” and “To” are considered. The “Find” function in Formula Finder uses all constraints, including the mass tolerance for all selected peaks in the isotope pattern and the settings from the Options dialog.

10/22/2020    SCIEX OS

How to Change the Font in a Report Template?

Use these instructions to change the font of the text appearing in a report.

10/22/2020    Software

Can I Use a Regular Expression (Regex) to Filter Data in SCIEX OS Software?

A regular expression (regex) can be used to filter data in a results tables and in reports created with SCIEX OS software.

10/22/2020    SCIEX OS

What Is the SCIEX OS Software Equivalent to the Area Threshold Feature in Analyst® Software?

SCIEX OS software does not have a field for the Area Threshold as found in the Analyst® software quantitation method wizard that allows users to set the criteria for peaks to appear as "not found" in a results table. Instead, a custom flagging rule must be created in SCIEX OS software to enable this type of filtering for peak area.

10/22/2020    SCIEX OS

What Cable Should I Use To Connect PAL3 to an Agilent Pump when Using Analyst® Device Driver?

A sync cable, called the PAL connecting cable APG Remote, should be used to connect the PAL3 autosampler to an Agilent pump when both the devices are configured through the Analyst® Device Driver (ADD).

10/22/2020   

Can Regular Expressions (Regexes) Used for Data Filtering in SCIEX OS Software Be Saved?

To export and import filter settings so they can be used across multiple results tables and projects in SCIEX OS software, a regular expression (regex) can be created using a custom filter in an existing results table. The custom settings can be exported as a .cset file using the Table Display Settings export feature and reapplied to another table using the Import feature.

10/22/2020    SCIEX OS

Can BioPharmaView™ and BPV Flex Software Coexist on the Same Computer?

BioPharmaView™ Software 3.x and BioPharmaView (BPV) Flex Software 2.x are compatible and can be installed on the same computer.

10/21/2020   

SQLite Exception Error in the Regulated Version of SCIEX OS Software

While setting up the regulated version of SCIEX OS software (CFR features activated), the following error message appeared when accessing the Audit Map portion of SCIEX OS software: "System.Data.SQLite.SQLiteException : unable to open database file." To resolve this issue, change the Windows permissions so that the user has full access to Audit Trail files.

10/20/2020    SCIEX OS

Is the Impurity Feature Available in BPV Flex Software?

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

10/20/2020   

What Software Is Supported for Analysis of Data from the Echo® MS System?

Once data collection from a well plate has been completed on the Echo® MS System, a .csv file is created for each well, in addition to another file that contains all of the data from the well plate. The .csv files can be imported into any data visualization software for further analysis, or the .wiff2 data can also be reviewed in SCIEX OS software. The data set contains the sample name, well location, component name, peak area, peak height, and peak width.

10/19/2020   

What is the Supported Control Software for the Echo® MS System?

The Echo® MS System is controlled by SCIEX OS software, version 1.6.10. This is the only supported software for direct control of this instrumentation. SCIEX OS software supports an open application programming interface (API) for the creation of integrated control through third-party automation software packages.

10/19/2020   

What Sample Matrices Are Supported on the Echo® MS System?

The sample matrices that can be supported on the Echo® MS system must correspond to one of the supported liquid classes, either AQ or SP.

10/19/2020   

Is It Possible To Monitor More MRMs Per Well than Specified for the Echo MS System?

Yes. The specified four MRMs per well is based on the peak width from a single droplet ejection.

10/19/2020   

Issue when Exporting and Importing Text Files into MultiQuant or SCIEX OS Software

Excel can insert extra characters in exported forms of the MultiQuant™ or SCIEX OS software data and corrupts this data; the resolution here is to edit the exported file and use another editor, other than Excel, that does not insert extra characters into text.

10/19/2020   

How To Provide Selective Access to Analyst® Software Projects

To set access for select users at the project level in Analyst® software, the security configuration must be updated.

06/11/2020    Analyst Software

Why Won't LipidView™ Software Load My Analyst® Software (.wiff) Data Files?

In order to load Analyst® software data files (.wiff files) into LipidView™ software, either Analyst or Analyst TF software must be installed alongside LipidView.

Locating the Most Recent Quantitation Method Used in MultiQuant™ Software

To locate the most recently used quantitation methods used in MultiQuant™ software, select the File menu and then select the Recent Quantitation Methods option. This menu option allows for the most recently accessed methods to be viewed.

05/14/2020    MultiQuant Software

Resolving the Analyst® Software RackBuilder.exe Error Message: Failed To Open Database AutosamplerPoetDb

When running the RackBuilder.exe, an error message is received: "Failed to open database AutosamplerPoetDb". This error can be cleared by setting the Windows User Account Control (UAC) settings to level 4 (Never notify) and then rebooting the computer.

05/14/2020    Analyst Software

Removing Rows Releated to Internal Standards from a MultiQuant™ Software Table

If its not desirable to view the internal standard information in a MultiQuant™ software results table, de-select the IS button by clicking on the binoculars icon in the Components & Groups column.

05/14/2020    MultiQuant Software

Locating the Name of a Server or PC Using the Command Prompt Window

This article describes the DOS commands used to access the name of the server or PC.

05/14/2020    Academia Omics | Software

C Drive Free Space Requirements when Using SCIEX OS Software

SCIEX OS software performs best when 20 GB of free space is available on the C drive (C:). Furthermore, SCIEX OS software creates log files in order to monitor both instrument (on an acquisition PC) and software (on both acquisition and processing PC's) performance. These log files incremently increase and can accumulate to a total size of 35 GB. This sets a limit of 55 GB of space needed on the C drive to use SCIEX OS software optimally.

05/14/2020    SCIEX OS

Locating the Name of a Server or PC Using the Command Prompt Window

This article describes the DOS commands used to access the name of the server or PC.

05/14/2020    Academia Omics | Software

How to Extract Multiple XICs in Separate Windows in Analyst® Software Explore Mode

Sometimes in the Analyst® software Explore mode, it's optimal to view individual extracted ion chromatograms (XICs) in separate panes instead of in the same windows when extracting multiple ions from a total ion chromatogram (TIC). To prevent multiple XICs from appearing in the same window, the Appearance Option settings in Analyst software will need to be adjusted.

05/14/2020    Analyst Software

Installing ProteinPilot™ 4.5 and 5.0.x Software on the Same PC

For software users who need to view the older group files, maintaining a separate computer with ProteinPilot™ software 4.0 installed is the recommended best approach. Alternatively, both versions, 5.0.x and an older version, can be installed on the same computer, but this is an unsupported configuration.

05/13/2020    ProteinPilot Software

Obtaining a Smaller Volume Divert Valve for a 4500, 5500 and 6500 LCMS Systems

To obtain a smaller volume divert valve for a 4500, 5500 or 6500 LCMS system, a new part must be ordered from Valco, part number of C52-2006I.

05/13/2020    Mass Spectrometers

DiscoveryQuant™ Software Will Not Launch Without Analyst® Software Installed

If DiscoveryQuant™ software fails to launch, even after the software is uninstalled and reinstalled, check to see if Analyst® software is also installed. An installed version of Analyst software is a prerequisite to installing DiscoveryQuant software; DiscoveryQuant software will not launch without Analyst software.

05/13/2020    DiscoveryQuant Software

Printing an Unsecured Report as a PDF with MultQuant™ or SCIEX OS Software

Reports printed as PDF files from either SCIEX OS or MultiQuant™ software are always secure because they are printed using pdfFactory. A workaround must be used to print unsecured PDF reports.

05/13/2020    SCIEX OS | MultiQuant Software

Obtaining Intensity Information from an IDA-EPI MS/MS Spectra

To obtain the intensity information from an IDA-EPI MS/MS spectra, the ProteoWizard data conversion tool, MSConvert, can convert SCIEX data files (.wiff and .wiff.scan) to other formats using MSConvert besides mzML, such as MGF or txt formats. These non-mzML formats create larger files but provide the spectral data in simple mass/intensity text.

05/13/2020    Software

Altering Parameters in PPG Tuning Methods Causes Mass Shift and Resolution Issues

Changing any of the source or compound parameters in a PPG tuning method (such as Q1PosPPG.dam located in the API Instrument project folder in the Analyst Data folder) causes mass shift and resolution issues in the resulting data file.

04/30/2020    Analyst Software

What Library Database File Types Can Be Imported into LibraryView™ Software 1.4?

Many different types of compound and library databases can be imported into LibraryView™ software version 1.4. The following options for source files are acceptable for importing library compounds into LibraryView software: LibraryView Package (*.lbp), DiscoveryQuant™ Compound Database (*.mdb), Analyst® Compound Database (*.mdb), Cliquid® Package (.clq), Excel file (*.xls), Overwrite Database with LibraryView Snapshot (*.lbp), and Third Party Library Package (*.tplp)

04/29/2020    LibraryView Software

What Is the Correct Format for the Client License Text for Software Using a Concurrent License?

To create and set up the license on the client PC for software using concurrent license server, the license text should be formatted as follows: SERVER [SERVERNAME.DOMAIN.COM or IP ADDRESS] ANY [PORT NUMBER] VENDOR ScxMSSW0 USE_SERVER

04/28/2020    Software

What Is the Best Way to Back Up My Library Compounds in LibraryView™ Software?

This article provides some guidance on best practices for backing up your library compounds stored in LibraryView™ software. Its recommended that a snapshot is created of the library every time the library is updated or edited.

04/28/2020    LibraryView Software

What Are the Most Common Installation Issues for SCIEX OS Software 1.7?

Some of the most commonly observed installation issues with SCIEX OS software 1.7 are summarized here. Instructions on how to uninstall previous versions of SCIEX OS software are also included.

04/28/2020    SCIEX OS

What is the Analyst® Diagnostic Tool and How Can It Help Me?

Analyst® Diagnostic Tool is an information-gathering program that is designed to provide insight on performance issues with Analyst software and the computer's operating system.

04/17/2020    Analyst Software

Missing Columns when Exporting the Protein Summary from ProteinPilot™ Software 5.0.2?

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

Checking for Administrator Rights on a Windows 10 PC before Installing Analyst®/SCIEX OS software

There are three simple steps to determine which Windows users are listed as administrators before installing SCIEX software.

04/16/2020    Software

Is Cliquid® 3.4 Software Compatible with MPX™ 2.0 Software?

MPX™ Software is compatible with Cliquid® software and can be operated through the Cliquid software console; however, the Cliquid software Walk-up mode is not available.

04/16/2020    Cliquid Software | MPX Software

Which Version of Watson LIMS Is Compatible with SCIEX OS Software 1.7?

SCIEX OS software 1.7 has been tested with Watson LIMS server/client version 7.6, Oracle server/client 12.2.0.1.0 SE (64-bit) and 12.2.0.1.0 (32-bit).

04/16/2020    SCIEX OS

Is Digital PicoView® Source Windows 10 compatible?

Digital PicoView® Source is a nano ion source from New Objectives that is Windows 10 compatible and can be used with many SCIEX mass spectrometers.

SCIEX OS 1-5 Software

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

04/16/2020   

Setting Up Email Notifications for Reports in Cliquid® Software

To allow the system to deliver email notifications of reports generated in Cliquid® software, select Run Samples. In the menu option Set report options, users can choose to set up the email notifications for completed reports or indicate their preference to have a pdf version of the report emailed to them directly.

04/16/2020    Cliquid Software

Windows 7 and 10 Operating Systems Are Compatible with Analyst® Administrator Console 3.0

Windows 7 and 10 operating systems are compatible with Analyst® Administrator Console 3.0 software.

04/16/2020    Analyst Software

Accessing ProteinPilot™ Software Searching in the SCIEX Cloud Workspace

To log into the SCIEX Cloud workspace and access the ProteinPilot™ software searching features with just your CloudConnect license, follow the instructions below.

How to Determine if the Acquisition PC Has a Bad Ethernet Card?

This article summarizes some issues that might contribute or confirm a bad network card.

04/16/2020    Mass Spectrometers

How to Export UV Data into a Text File in SCIEX OS Software

Open a data file that also contains UV data in SCIEX OS software in the Explorer module. Locate the Show menu and select UV/DAD/ADC Channel. Once UV trace is displayed, click Data and Peaks Table under the Show menu to display the table. Export the data by right clicking on the table and selecting Export Data as Text from the menu.

04/14/2020    SCIEX OS

Removing Server Path Names in the MultiQuant™ Software LIMS Transfer Dialog

In order to enter the correct server address to enable LIMS transfers in MultiQuant™ software, delete the FilesFolderOptions.xml file in the folder C:\Users\User.Name\AppData\Roaming\AB SCIEX\MultiQuant3 and then restart the software.

04/14/2020    MultiQuant Software

Unable to Import Batch Files in XLSX Format in the Batch Editor in Analyst® 1.7 Software

Importing an XLSX batch file into Analyst® 1.7 software may cause an error, and the batch file import will not be successful. The XLSX format is only available if the version of Microsoft Office that is installed is a 32-bit application. Users with a 64-bit version of Office will see these batch import errors, and must install additional software components to support XLSX type spreadsheets with Analyst software.

03/20/2020    Analyst Software

How To Create an Unsecured PDF Report in Sciex OS Software

In order to create reports in SCIEX OS software in the portable document format (PDF) that are unsecured, the PDF setting in the SCIEX OS config file will need to be updated. Please follow below instructions to edit the config file.

03/20/2020    SCIEX OS

How to Install Skyline Software on an Off-Line Computer

To download Skyline software on a computer that is not connected to the internet, use the Unplugged installer or the Administrator installer:

How to Group Analytes in an Analyst® Software Results Table

To place multiple analytes (or multiple transitions for the same analyte) into a group within a results table in Analyst® software results table, follow the steps outlined in this article.

03/20/2020    Analyst Software

Where Are the Report Templates for BioPharmaView™ Software Stored?

The file folder locations of the report templates for BioPharmaView™ software are listed in this article.

How Do I Create a Dump File?

A SCIEX technical support agent may ask you to create and send a dump file to provide a snapshot of a SCIEX software application's processes, loaded modules and memory at a certain time point. This article explains how a dump file is created.

03/20/2020    Software

Can Xcalibur Software 3.x and Eksigent Software 4.3 Operate on Windows 10?

SCIEX's Eksigent software and Thermo Scientific's Xcalibur software have not officially been tested together on a Windows 10 operating system. The Eksignet software can be installed on a Windows 10 PC, but then it cannot be configured with any Xcalibur software versions. However, both software types can be configured together on a system running Windows 7, 64-bit.

03/20/2020    Academia Omics | NanoLC 400

How to Add Select Samples to a Report Created in SCIEX OS Software

To add only selected samples from a results table created in SCIEX OS software in a report, uncheck the Reportable column for the sample you do not want to report. Then edit your report template to include an If statement within a ForEachSample loop to include $Reportable="TRUE".

03/20/2020    SCIEX OS

Sciex OS Software Report Error: An Item with the Same Key Has Already Been Added

An error was received while using Sciex OS software to generate a report: "Error during Report generation. An item with the same key has already been added." No report was generated. To resolve this issue, open the report template and see if a query file is linked through the Meta Field tag. If a query is linked, open the query and evaluate it for any duplicate column names. Delete any duplicate columns from the input sheet.

03/20/2020    SCIEX OS

Which Folders Should Be Backed Up Before Upgrading the SCIEX OS Software?

Prior to upgrading or removing SCIEX OS software, back up the SCIEX OS Data folder and the SCIEX folder in the Program Data folder.

03/20/2020    SCIEX OS

Location of the Event Logs for the MPX 2.0 Driver Software System

The event logs for the MPX 2.0 driver software system are saved under C:\Program Data\SCIEX\MPX Driver\Log\.

03/20/2020    MPX Software

Is the MPX™ Driver Software System Compatible with Analyst® MD software?

The MPX™ driver software system is not supported with Analyst® MD software. Compatible LC systems are listed in the installation guide for Analyst MD software.

03/20/2020    Clinical | Forensics | Analyst Software

How To Enable the New Intact Protein Quant Feature in SCIEX OS 1.7 Software

The Intact Quant feature in Sciex OS 1.7 software platform enables the quantitative processing of intact proteins without sample prep and allows for the complete and compliant intact reconstruction of protein data sets. To activate this feature, an additional, add-on software license, SCIEX OS IntactQuant 1.7 (part number 5078597), must be installed in the C:\ Program Files\SCIEX\SCIEX OS folder.

03/17/2020    Academia Omics | Pharma CRO | SCIEX OS

Using an External Calibration Curve in SCIEX OS-MQ Software

To use an external calibration curve with a results table created in SCIEX OS-MQ software, use the Export calibration (and save results...) feature in the Options menu after the calibration curve has been generated.

03/17/2020    SCIEX OS

Common Project Area Folder Write Access Error in SCIEX OS Software

When creating a new project in SCIEX OS software, the following error was received: The current user does not have write access to the requested project. This issue was resolved by copying the common-project-area folder in the SCIEX OS Data folder over from a different PC with an intact root directory.

03/06/2020    SCIEX OS

How To Generate a List of All Installed Programs and Windows Updates

To generate a list of all programs installed on a PC and a list of Windows updates, select the Programs and Features icon in the control panel. A list of all installed Windows updates can be created from the View Installed Updates screen.

02/21/2020    Software

Upgrading SCIEX Software Licenses

How to upgrade self-upgrade registered software licenses

01/27/2020    Software

General Guidance for Antivirus and Backup Software Used on Acquisition PCs

The antivirus or backup software on Analyst® software acquisition workstations should be configured in a manner that will disable real-time scanning and archiving of files in the Analyst Data folder.

12/26/2019    Software

What Is the Exact Mass that iTRAQ® Reagents Add to Peptides?

SCIEX does supply the masses of the labels in the iTRAQ® Reagent 4plex and 8plex kits, but masses with more significant figures can be found at www.unimod.org.

12/18/2019    iTRAQ Reagent

How Is a Formula Column Added to a Result Table in Analyst® Software?

To add a formula column to a results table in Analyst® software, right click on the results table and select Add Formula Column.

12/17/2019    Analyst Software

Why Do the Calculated Concentration Values Show as Degenerate in SCIEX OS Software?

In SCIEX OS software, if a value in the Calculated Concentration column displays as degenerate, this is because the values for Actual Concentration for standard samples have not been added to the results table.

12/16/2019    SCIEX OS | MultiQuant Software

What Parameters in ProteoWizard Are Needed when Converting .wiff2 Files to mzXML Files?

The parameter settings, including the PeakPicking value, that are used for converting .wiff2 files to mzXML or mzML files in ProteoWizard, are explained in more detail here.

Reporter 3.2: How To Report Calculated Concentrations of "<0" or "N/A"

If a MultiQuant™ or Analyst® software results table contains values of "<0" and "N/A" for some calculated concentration values, these text values must be converted to a numerical zero value first using an Excel query. These calculated concentration values cannot be filtered into a Reporter Template Suite 3.2 results template using an if statement that selects for calculated concentration values that are less than or equal to zero.

12/16/2019    Software

Saving Custom Columns As Default Columns in MultiQuant™ Software

To routinely add the same custom columns to each newly generated MultiQuant results table, custom columns can be added to the table in the Batch Editor in Analyst® software that is created before acquiring a data set.

AB SCIEX Data Explorer® Software Issue: Periodic Table and Other Software Features Are Grayed Out

The AB SCIEX Data Explorer® software is an embedded software for data processing on the 4800 MALDI TOF/TOF™ and the TOF/TOF™ 5800 Systems and was recently rebranded; however, the rebranding process caused certain applications menu items to become grayed out (periodic table, isotope calculator, and elemental composition). To resolve this issue, install the patch provided in the link in this article.

11/14/2019    Academia Omics

Does the XCMSPlus Software Use MS/MS Data Matching to Identify Metabolites?

XCMSplus software does not use MS/MS matching to identify features. Instead, this software identifies features based on the precursor m/z.

Causes of the taglet.exe Error in ProteinPilot™ Software

The taglet.exe error in ProteinPilot™ software is due to a wide range of issues including incorrect language settings, installation of the software on the incorrect operating system, and the incorrect addition of modifications — to name a few.

Does My Acquisition PC Have a Bad Ethernet Card?

This article summarizes some issues that might contribute to a bad network card.

11/13/2019    Software

The Peakfinding Algorithm in SimGlycan® Software Improves Search Results on SCIEX Datasets

The Peak Detection & Picking feature in SimGlycan® software versions 5.9.2 and higher offer an improved peak-picking algorithm that is faster and more efficient at handling data from SCIEX TripleTOF® LC-MS/MS System instruments.

11/12/2019    Academia Omics | SimGlycan Software

Why Use the Enterprise Edition of SimGlycan® Software?

SimGlycan Software (a product of PREMIER Biosoft) predicts glycan and glycopeptide structures from SCIEX mass spectrometer-acquired MS/MS data. Some of the advantages of using the enterprise edition of SimGlycan software include being able to create glycan templates so that novel glycan structures can be added to the database.

11/11/2019    Academia Omics | SimGlycan Software

What is SimGlycan Software?

SimGlycan® software is a comprehensive glycan and glycopeptide drawing and structure analysis software.

Does SimGlycan® Software Use .wiff2 File Formats from X500 Series Instruments?

This article describes the possible file input formats for SimGlycan® software.

Upgrading to Analyst® TF Software 1.8.1: Batch Editor No Longer Displays Autosampler ekspert nanoLC400 as an Option

After upgrading Analyst® TF software 1.8 to version 1.8.1, the Eksigent control software no longer displayed the option to chose the ekspert™ nanoLC 400 autosampler. To resolve this issue, in the Eksigent control software, the autosampler driver for the nanoLC 400 must be unregistered and then re-registered.

Reporter 3.2: Including Only the Results for the Quantifier Ion in a Report

To include only the data associated with the quantifier ion in a report, group the quantifier and qualifier ion for a particular analyte, and then use the For Each AnalyteGroup loop around the information to be reported.

LightSight® Software Acquisition Mode Is Not Supported on a SCIEX 6500+ LC-MS/MS System

LightSight® software version 2.3.x acquisition mode is not supported on a SCIEX QTRAP® or Triple Quad™ 6500+ LC-MS/MS System.

SCIEX OS Software: How to Choose the Format for a Numerical Field in a Report

By default, the format for a numerical field in a report is taken from the results table itself if the format is not set in the report template tag. If a specific numerical format is desired for a particular field in a report, certain default formats (such as the number of decimals desired or scientific notation) can be chosen in the Format field in the tag for that value. Otherwise, In the SCIEX OS software results table itself, the number format can be set for individual columns by editing the Number Format in the Results Table Display Settings options.

Aliquots of Bulk iTRAQ® Reagent Require Cold Storage Under Inert Gas

When aliquoting bulk iTRAQ® reagent, vials must be stored at -20 °C under inert gas.

11/09/2019    Academia Omics | Pharma CRO | iTRAQ Reagent

What Is the Settling Time in an Analyst® Software Acquisition Method?

In Analyst® software, the settling time is defined as the time that a mass spectrometer pauses after finishing a cycle until it begins the next cycle. The instrument electronics require a settling time in order to function successfully.

11/09/2019    Mass Spectrometers

SCIEX OS Software: Internal Standard Data in Report Does Not Match the Results Table

If a report generated from SCIEX OS software using a template and a query contains information about internal standard samples, the internal standard information showing in the results table does not appear correctly in the report. To resolve this issue, all internal standard samples must be listed at the bottom of the SCIEX OS software processing method in the components section.

11/09/2019    SCIEX OS

No Help Topics Appear in the SCIEX OS Software Help System

Selecting the question mark in the upper right hand corner of SCIEX OS software launches the SCIEX OS Help System screen. If no information appears for a selected topic, the SCIEX OS Help.chm file located in the C:\Program Files\SCIEX\SCIEX OS\Documentation folder needs to be unblocked.

11/09/2019    SCIEX OS

Modifying a Report Template to Report Select Sample Types Using IF Statements

An IF statement can be added to limit the sample types that need to be output to a report from a results table created in Analyst® software, MultiQuant™ software or SCIEX OS software. Below are few examples of how to write an IF statement within the loops ForEachSample or ForEachAnalyte.

Where are the SCIEX OS Software Report Templates Located on My PC?

If a report template needs to be opened for editing or if a new custom template needs to be added to the template list in SCIEX OS software, then navigate to C:\ProgramData\SCIEX\Analytics\Reporter to locate or add a template.

11/08/2019    SCIEX OS

Direct LIMS Transfer in SCIEX OS Software Does Not Require a Template

Transferring data to a LIMS system from a results table created in SCIEX OS software does not require a template. Once the results table is saved and locked, under the Reporting menu, select Transfer results to LIMS, and two LIMS export options will appear in the LIMS transfer dialog box.

11/07/2019    SCIEX OS

What Are the Functions Available to Each Security Configuration Role in Analyst® Software?

Individual users of Analyst® software can be assigned a particular role in Analyst software in the Security Configuration mode. The various roles are designed to limit a user's access to certain functions within the software depending on the role assigned. Below is a chart that shows how access to these functions decreases for the various default roles.

11/07/2019    Analyst Software

Adjusting the Dilution Factor Corrects Calculated Concentrations in Analyst® Software for Known Samples

If the dilution factor is not set correctly in an Analyst® software results table, the calculated concentration values for samples of known concentration will be incorrect.

11/07/2019    Analyst Software

Adding Custom Columns In a Batch in Analyst® Software

To add a custom column(s) to a batch in Analyst® software, right click within the batch table on the Sample tab, and select Add Custom Column.

11/07/2019    Analyst Software

Can the Loops ForEachSample and ForEachVisibleSample Be Used in the Same SCIEX OS Software Report Template?

No, the loops, ForEachSample and ForEachVisibleSample, cannot be used within the same SCIEX OS software report template. Similarly, ForEachAnalyte and ForEachVisibleAnalyte cannot be used together in the same report template.

11/01/2019    SCIEX OS

MultiQuant™ Software Report Error: Object Reference Not Set to an Instance of an Object

If the MultiQuant™ software error "Object reference not set to an instance of an object" appears when creating a report, then the report template was not selected in the Create Report dialog. Check the file being used in the Report template field is a true report template. If not, replace it with a correctly formatted report template.

10/29/2019    MultiQuant Software

Problem Uninstalling SCIEX OS Software Stems from Hidden SQL Driver

While removing the SQL 2008 R2 Setup program during a SCIEX OS software de-installation, an error was received—indicating that the issue was due to the 2008 R2 RsFx driver, a "hidden" program that needs to be manually uninstalled using either the command prompt or regedit Windows functionalities.

10/29/2019    SCIEX OS

Setting Up a New Project in Analyst® Software

To set up a new project in Analyst® software, navigate to the Tools menu and select Project.

10/25/2019    Analyst Software

How to Update or Link a Query File to a Report Template

If the name of a query is ever changed or updated or if a new query needs to be attached to a report template, the query must be relinked to the template used for reports created in MultiQuant™, Analyst® or SCIEX OS software.

What Integration Algorithms Are Used by SCIEX OS Software?

The SCIEX OS software has three integration algorithms that can be used to integrate peaks, and these options are listed in the Project Default Settings in the Analytics module: MQ4, AutoPeak and Summation.

10/22/2019    SCIEX OS

Resolving the Report Error in SCIEX OS Software: "Error during Report generation"

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

10/22/2019    SCIEX OS

Report Template Editing Blocked after Upgrading SCIEX OS 1.6.1 Software from a Previous Version

After updating SCIEX OS software from version 1.5 to 1.6.1, report template may be unable to be edited if Analyst® software is installed on the same PC. An error message appears in the Microsoft Word report template document: "Reporter Office addin. The provider with the name Quantitation already added to content control addin.Multiple custom type XML files found for the same provider." This article explains how to resolve this issue.

10/22/2019    SCIEX OS

What Is the Format of a LIMS Template?

A LIMS template is used to transfer data from a MultiQuant™ software results table to a LIMS system. The LIMS template is a comma delimited file with the fields to be output listed across the top of the report. Each field in the template should be separated by a comma.

10/22/2019    Software

Changing the Integration Algorithm in SCIEX OS 1.6.1 Software

To change the integration parameter used in a quantitative processing method in the Analytics module of SCIEX OS Software, select the Projects menu, and under the Projects default settings, select Quantitative Processing > Integration Defaults > Integration Algorithm.

10/17/2019    SCIEX OS

Absence of Calibration Curve in Analyst® or MultiQuant™ Software Due to Omitted Standard Concentration Values

If actual concentration values for standards are omitted from a MultiQuant™ or Analyst® software results table, then the data points for standard concentration versus peak area will all be aligned with zero on the x-axis in the calibration curve, looking nothing like the expected diagonal line. Adding the actual concentration information for the standards spreads the points across the x-axis and restores the expected diagonal linear regression line.

What File Format Can Report Templates Be Created In?

Report templates—used to create reports from results tables generated in Sciex OS, MultiQuant™ and Analyst® software—must always be in the format of a Word document with a file extension .docx. However, the output report itself can be created in several formats including Word, HTML, PDF, and CSV.

How to Access the SCIEX OS Software Help Menu

To access the SCIEX OS software help menu, click on the question mark in the upper, right-hand corner.

10/16/2019    SCIEX OS

Where are the Cliquid Software Report Templates Located?

The Cliquid® software report templates are saved in the folder D:\Analyst Data\Projects\Cliquid\Templates\ReportTemplates.

10/16/2019    Cliquid Software

Ensuring the Positive Hits Report Includes Only Positive Hits from a Results Table Generated in SCIEX OS Software

To ensure that only the positive hits appear in a report generated using the Positive Hits template rather than all visible results in a results table, the results table itself first needs to be filtered to show only positives prior to running the report.

10/16/2019    SCIEX OS

Data for Custom Calculations Show as Not Calculated on a Report

In reports created from results tables in Analyst® and MultiQuant™ software, queries are used to compute the values for custom calculations, but occasionally the data appears as "Not calculated" on the report. This issue appears when the query file linked to the report template is not saved to the same folder as the report template.

Centering a Peak in a SCIEX OS Software Peak Review Pane

To adjust the location of the peak in the window and to center it, select the peak review icon in the results table, click Options and then Peak review display settings. In the Zooming tab, select the Zoom time axis to view peak check box and add the desired retention time.

10/11/2019    SCIEX OS

Can the ChemoView™ Software LIMS Template Be Edited?

Yes, the LIMS template for ChemoView™ software can be edited and customized. Once changes are saved in the report template, the report output will reflect the changes.

10/10/2019    ChemoView Software

Creating a New Report Style in Cliquid® Software

To create a new report style in Cliquid® software, go to the Administrator Tasks (Home) menu, then select Manage Report Styles and Create a Report Style.

10/10/2019    Cliquid Software

To Make Reporter Tags Visible in a Report Template Unblock Them

If a report template is emailed or transferred to another computer and then opened, the xml tags may not be visible because they were blocked for security reasons.

Can the Default Location of MultiQuant™ Software Queries Be Changed?

It is not possible to change the default location of MultiQuant™ software queries.

10/09/2019    MultiQuant Software

Can Standard Concentration Values Be Stored in a MultiQuant™ Software Quantitation Method?

No, the concentration values for a standard or quality control samples cannot be stored in or saved to the MultiQuant™ software quantitation method.

10/09/2019    MultiQuant Software

LeadScape Software and LeadSampler (LS-1) Compatibility with Exion AD Pumps

The Exion AD pumps sold by SCIEX are compatible with Sound Analytics' LeadScape software and the LeadSampler (LS-1) autosampler.

10/07/2019    Analyst Software

Reinstalling Analyst® Software without Uninstalling Analyst® Device Driver Will Cause Acquisition Methods To Fail

When installing the Analyst® Device Driver with Analyst® software, the order of installation of the programs is important. The Analyst software must be installed first, and then the Analyst Device Driver is installed next.

10/04/2019    Analyst Software

File Locking Prevents Addition of Remaining Injections to Existing Analyst® Software Data Files

To add injections to an existing data file, ensure that the Analyst® software data file is not in use or locked by another software program.

10/04/2019    Analyst Software

Unable to Configure a Shimadzu LC System after Upgrading to Analyst® 1.7 Software

A Shimadzu LC system may not be recognized and may not be able to be configured after an upgrade to Analyst® 1.7 software if a computer image on the PC was not sourced from SCIEX.

10/04/2019    Analyst Software

Migrating the SQL Server from DiscoveryQuant™ 2.1 Software to Version 3.0.x

Instructions are provided here for migrating the SQL server for DiscoveryQuant™ 2.1 to an installation of DiscoveryQuant 3.0.x software.

10/04/2019    Pharma CRO | DiscoveryQuant Software

Unlocking the Secure PDF Files Created by SCIEX OS Software

To unlock a secure PDF file created using SCIEX OS software reporter, open the document in a web browser and then print the newly opened document using either Microsoft Print to PDF or Save As PDF.

10/04/2019    SCIEX OS

Migrating an Analyst® Software Compound Library to Sciex OS Software

To migrate compounds in an Analyst® software library to Sciex OS software, navigate to the Library module in Sciex OS software, and select Analyst Compound Library in the import options. The imported library must be named. Instructions for naming the library are included here.

Increasing the Maximum Injection Volume for an MPX™ Software System

To change the default injection volume in MPX™ 1.2.1 software, the MaxInjectVolume line in the MPX configuration file (Multiplex.INI) can be edited. Additionally, the value added to the injection volume field in the Analyst software batch editor (on the Sample tab) will override the configured MPX injection value during an acquisition run.

10/03/2019    MPX Software

How Are Analytes Deleted from a Processing Method in Sciex OS Software?

To delete unwanted analytes from a processing method in Sciex OS software, highlight the rows, right click and select Delete Rows.

10/03/2019    SCIEX OS

How Can Library Hit Results Be Filtered by Score in a SCIEX OS Software Results Table?

To filter library hit results in a SCIEX OS software by library score and to remove any results without a proper score (presenting with N/A), a custom filter can be used in the Analytics mode.

10/02/2019    SCIEX OS

Entering the Formula for a Stable Isotope Labeled Compound in SCIEX OS Software

To enter the formula for a stable-isotope-labeled compound in the Components tab of a processing method in SCIEX OS software, some specific rules must be followed. When entering the formula, the atomic mass of the isotope is added before the single letter chemical abbreviation of the element, and then the total number of atoms of each isotope follows the chemical symbol.

10/02/2019    SCIEX OS

Resolving Analyst® 1.6.3 Software Launch Error: Cannot Find the File Usernameanalyst.exe

To resolve the error "Cannot find the file usernameanalyst.exe" when opening Analyst® 1.6.3 software, the format of the Windows username on the computer where Analyst software was installed could not contain a period or a space in the middle of the user name. Reformatting the text of the Windows usernames resolved the issue.

10/02/2019    Analyst Software

Tips for Setting Up a Test in Watson LIMS™ Software for Use with Analyst® Software

This article summarizes some helpful hints for setting up a test in Thermo Fisher™ Watson LIMS™ software for use with Analyst® software.

10/01/2019    Analyst Software

Longer Power Cycle May Help To Resume Instrument Connectivity after Power Failure

Even after resetting the mass spectrometer (by following the power-cycling procedure), the instrument would not come back online after a power failure. On some occasions, the mass spectrometer must be completely powered down for at least 1 min in order for the circuits to discharge and fully release any faulty information.

10/01/2019    Mass Spectrometers

After Upgrading Analyst® Software, Why Do Data Files Include xx.wiff.scan Files?

After upgrading Analyst® software, some data files now include xx.wiff.scan files. In the Configure mode in Analyst software, navigate to the Tools and Queue Options menu. Deselect the Use flat files for scan data button to prevent the xx.wiff.scan files from being created.

10/01/2019    Analyst Software

Setting the Low Limit Value in the MPX 2.0 Software for Real-Time Data-Dependent Decision (RTD3) Flagging

When setting up MPX 2.0 software's carryover detection feature in the Define limit values screen (step 3), the low limit for each component must be defined using the lower limit of quantitation (LLOQ) or from the cut-off limit determined from the standard curve.

09/29/2019    MPX Software

Where Can the Software for StatusScope® Remote Monitoring Service Be Accessed?

To obtain access to the software download for StatusScope® Remote Monitoring service, users who are under warranty or who have purchased the service can navigate to statusscope.absciex.com and select the link to the software download.

09/29/2019    Mass Spectrometers

Exporting and Importing a Flagging Rule in SCIEX OS Software

Flagging rules for IS Recovery can be exported from an existing method in the Analytics workspace of Sciex OS software, and then the exported file can be re-imported into a new processing method using the Export/Import functions in the Flagging Rules screen.

09/29/2019    SCIEX OS

Recommendations for Waters Driver Packs with Different Analyst® Software Security Modes

When installing Analyst® software with the Waters' Driver Pack 4 (DP4) or the Driver Pack 4 supplemental release (DP4 SR1), consideration must be given to the Analyst security mode setting that is selected.

09/27/2019    Analyst Software

Resolving SCIEX OS Software Error: Cannot Open LibraryViewServiceHost Service on Computer

When trying to access the Analytics mode in SCIEX OS software when logged into Windows as a user without administrative privileges, an error is received: "Error has occurred: Cannot open LibraryViewServiceHost service on computer '.'. LibraryView service must be running." The LibraryViewServiceHost was not started when the Analytics mode was opened, and a workaround needs to be used to launch it.

09/27/2019    SCIEX OS

Does BPV Flex Software Support Multiple Period Experiments?

BPV Flex can only open the first period of multiple period experiment runs.

09/27/2019    Pharma CRO | BioPharmaView Software

Why Is There a .Special File Placed in the SCIEX OS Software Project Folders?

SCIEX OS software creates a special placeholder file (with a file extension of .special) and places these files in the root of every known SCIEX OS project sub-folder. SCIEX OS software uses both the project folder names and the .special files to identify its known folders, and it will not recognize the folder if the .special files are removed.

09/26/2019    SCIEX OS

How Very High Concentration Samples Are Handled in MPX 2.0 Software

MPX™ 2.0 software contains a feature for automated carryover monitoring, which can identify samples above a certain threshold.

09/26/2019    MPX Software

Preventing IP Address Conflicts with SCIEX 5500/6500+ Series MS and Waters' Acquity LC Instruments

To eliminate the possibility of any IP address conflict, the Waters IP addresses should be changed when operating with a SCIEX 5500/6500+ series instrument. To change the IP address on a Waters' LC components, use the Waters DHCP configurator located in the following folder: C:\\Program Files\Waters Instruments\Waters DHCP Server Configuration.exe.

09/26/2019    Analyst Software

Resolving the PeakView™ 2.2 and MultiQuant™ 3.0.3 Software Error after Upgrading to .NET 4.7.2

After upgrading PeakView™ software to version 2.2 or MultiQuant™ software to version 3.0.3, the following error message was generated: "The procedure entry point nextafterf could not be located in the dynamic link library MSVCR120_CLR0400.dll." The workaround is to remove .NET Framework 4.7.2 and then install the .NET 4.0 software.

Multiple Period Experiments Cannot Be Processed in BioPharmaView™ Software 2.x and 3.x

Data processing for intact proteins and peptide mapping in BioPharmaView™ software versions higher than 2.x do not allow for multiple period experiments.

How Many User Roles Are Available in ChemoView™ Software?

ChemoView™ software supports two user roles, technician and administrator. Each role allows access to different rights and functions within the software.

09/25/2019    ChemoView Software

Creating a Processing Method in ChemoView™ Software

To create a new processing method in ChemoView™ software, select the Add New Processing Method button.

09/25/2019    ChemoView Software

Defining Analyte and Analyte Type in ChemoView™ Software

To define a new analyte in ChemoView™ software, navigate to the Manage/Analyte module, and select the Add New Analyte button.To define analyte type, select the Setup menu and chose the Analyte Types option.

09/25/2019    ChemoView Software

Setting the High Limit Value in the MPX 2.0 Software for Real Time Data-Dependent Decision (RTD3)

In the MPX software 2.0, the carryover detection feature requires that the values for the high or region height columns need to be defined for each component. These values are used to set the flag for the above upper concentration limit.

09/24/2019    MPX Software

Can SCIEX OS and MasterView™ Software Be Installed on the Same Computer?

SCIEX OS and MasterView™ software are not compatible, and they cannot coexist on the same computer.

09/24/2019    SCIEX OS | MasterView Software

Finding the Archived Results in Chemoview™ Software

All result reports are archived in Chemoview™ software in the Results Archive tab. Users can browse the report by job date, or search job by date, .wiff file name and sample name.

09/23/2019    ChemoView Software

Adding Users to the SCIEX OS Software Security Database

To add users to SCIEX OS software Security Database, the user who installed the software needs to navigate to the User Management section in the Configuration mode and select the plus sign next to the User name or group drop-down menu.

09/23/2019    SCIEX OS

How Do I Generate a Report with Only the Quantifiers in SCIEX OS Software?

Open the Analytics workspace in SCIEX OS software and open a results table. In the More menu, click Table Display Settings. A list of column names will appear. Select Reportable to make this option visible. Selecting the Reportable column shows whether or not the result is included in reports, exports, and LIMS transfers. Under Reportable column, select Quantifiers for the component.

09/23/2019    SCIEX OS

Can Google Drive Be Used for Transferring or Storing Data Generated by SCIEX Software?

The use of Google Drive for data storage has not been tested with data sets generated on SCIEX software. Transferring and storing data using Google Drive has led to issues with data sets for some end-users because of a potential embedded encryption process in Google Drive.

09/10/2019    Software

DiscoveryQuant™ 3.0.1 Software HotFix 2 Gives Not Registered Error

Despite being properly registered, DiscoveryQuant™ 3.0.1 software with hotfix 2 gives the error message that it is not registered and must quit. The root cause of this error is the presence of multiple instances of DiscoveryQuant software installed on the same PC.

09/10/2019    DiscoveryQuant Software

Calculating the Theoretical Average Mass for an Intact Protein in BioPharmaView™ Software

BioPharmaView™ software uses the isotopic masses published by NIST online at: https://physics.nist.gov/cgi-bin/Compositions/stand_alone.pl. Please note that the results generated will be the same throughout all SCIEX software (e.g., PeakView™ and ProteinPilot™ software).

License Error when Launching LipidView™ 1.2 Software on Windows 10

When launching LipidView™ 1.2 software on Windows 10, a license error appears indicating that the license has expired, even when a permanent license has been installed. To resolve this issue, right click on the LipidView software icon and select Run as Administrator to launch the software.

08/09/2019    LipidView Software

Installing the Accurate Mass Metabolite Spectral Library 1.0

Installation of the Accurate Mass Metabolite Spectral Library 1.0 requires a valid license file in order to install the compound database. The library installer creates a folder for the Accurate Mass Metabolite Spectral Library in the Start > All Programs > AB SCIEX > Accurate Mass Metabolite Spectral Library folder. The library and user documentation are copied into this location.

08/09/2019    LibraryView Software

Sciex OS 1.5 Software Error: Processing Method Contains No Components or Is Incompatible

When opening a processing method in Sciex OS 1.5 software, an error was received, indicating that the method contained no components or was incompatible. Removing the sub-folder (C:\SCIEX OS Data\<PROJECT NAME>\Quantitation Methods\<Sub-Folder>) resulted in normal software operation.

08/09/2019    SCIEX OS

Where Can I Find My Service Package for SCIEX OS 1.6.1 Software?

Any service package generated for SCIEX OS 1.6.1 software can be found as a zipped (compressed) file at C:\ServicesPackages.

08/09/2019    SCIEX OS

Creating a Custom Enzyme in BPV Flex 1.0 Software

To create a custom restriction enzyme in BPV Flex 1.0 software, locate the digestion agents secction in the BPV Flex DataDictionary.xml file. Type an enzyme definition or Copy/paste a definition for the desired enzyme.

08/09/2019    BioPharmaView Software

Adding a New Flagging Rule in the Analytics Workspace of Sciex OS Software

To add a new flagging rule in the Analytics workspace of SCIEX OS software, open the Analytics workspace. Click Process Method and select New. Then select the Flagging Rules page and click Add Rule.

08/09/2019    SCIEX OS

How Are the Ion Ratio Flagging Rules Set Up in SCIEX OS 1.5 Software?

To set up the ion ratio flagging rules in SCIEX OS software, select a processing method and then select edit. The rules can be changed under Flagging Rules and Ion Ratio Acceptance options under this menu.

08/08/2019    SCIEX OS

Protocol for Resolving the SCIEX OS Error: SciexLibraryService Rejected the Session-Establishment Request

Use the following protocol to change the port 8081 to resolve the software error that occurs wtih both Sciex OS and MasterView/LibraryView installations: SciexLibraryService rejected the session-establishment request.

07/24/2019    SCIEX OS

What Is the Organic Solvent Used with iTRAQ® Reagents during Shipment?

All iTRAQ®, aTRAQ™ and mTRAQ® reagents are shipped in acetonitrile from the factory.

Does ProteinPilot™ Software 5.0.2 Support MALDI TOF/TOF™ Systems?

Description of which ProteinPilot™ software versions still support 4800 and 5800 MALDI TOF/TOF™ systems.

Are CloudConnect and SWATH® MicroApps within PeakView® Software Windows 10 Compatible?

The software package, PeakView® 2.2, CloudConnect 1.2 beta and SWATH® 2.0.1 software. is needed to perform the OneOmics workflow and/or SWATH protein data processing and is Windows 7 and Windows 10, 64-bit compatible.

Does SCIEX OS Software Have an Equivallent Security Configuration to Analyst® Software's Mixed Mode?

In Analyst® software, there are three security configuration modes available: Single User, Integrated and Mixed. Are there functional equivalents of all three available in SCIEX OS software? In short, no, there are not.

07/14/2019    SCIEX OS | Analyst Software

Converting MultiQuant™ Software Qmethods to Sciex OS Software Qmethods

This article contains a step-by-step guide for converting a MultiQuant™ 3.0.3 software quantitation method (.qmethod) file to a Sciex OS 1.5 software quantitation method file (.qmethod).

06/26/2019    SCIEX OS | MultiQuant Software

Can Skyline Version 4.2.1 and Higher Process .wiff2 File Formats?

Yes , Skyline version 4.2.1 can process .wiff2 files generated using SCIEX OS software.

Resolving Hexadecimal Errors when Creating Reports in MultiQuant™ Software

If the error "Incorrect Argument. Hexidecimal value 0x1F is an invalid character" is received when creating reports with MultiQuant™ software, trailing spaces from the sample name need to be removed.

05/24/2019    MultiQuant Software

Verifying if .NET Framework 3.5.1 Is Installed on a Windows 7 Operating System

To verify if .NET Framework 3.5.1 is installed on a PC running a Windows 7 operating system, the .NET Framework Verification Tool may need to be deownprogram in the link provided.

05/24/2019    Software

General SQL Installation Errors for SCIEX OS and LibraryView™ Software

Installing any program with SQL-based software components (e.g., SCIEX OS and LibraryView™ software) requires that a certain rules are observed. These rules are set by Microsoft, and are not covered in the release notes for the SCIEX software installation that includes the additional of SQL components.

05/23/2019    SCIEX OS | LibraryView Software

Upgrading MultiQuant® software to 3.0.3 Version Results in Access is Denied Error

After upgrading MultiQuant® software 3.0.2 to 3.0.3 on Windows 10, the software initially launched. But when the software was accessed later, an error was received: "Access is denied".

05/23/2019    MultiQuant Software

Analyst® Software Error Message: Failed To Set Sample Data

If the error message "Failed to set sample data" appears when using Analyst® software, the issue may be resolved by reducing the number of racks in the batch to only those that were actually used for samples.

05/17/2019    Analyst Software

Resolving a Shimadzu LC Fatal Error: Could Not Activate Profile in Analyst® Software

The LC/MS hardware profile containing a Shimadzu LC could not be activated in Analyst® software. Under the Configuration tab for the Shimadzu system controller (CBM), the serial port filed was selected and changed to TCP/IP. The IP address 192.168.200.99 was added.

05/17/2019    Analyst Software

Exporting Libraries from MasterView™ Software to a New Computer

To use the set of libraries imported into MasterView™ software on another PC – or to switch between two sets of libraries – consider using the command line tools to export the library snapshot.

05/14/2019    MasterView Software

Compound Parameters Not Loading in Analyze Mode in DiscoveryQuant™ 3.0.1 Software

Compound parameters could not be uploaded in Analyze mode in DiscoveryQuant™ 3.0.1 software after switching from a local database to SQL database due to issues with the database selected as the review database.

05/14/2019    Pharma CRO | DiscoveryQuant Software

System Error Causing SCIEX OS Software Acquisition Stoppage Resolved by Clearing Data Folder

Sample acquisition using Sciex OS 1.5 software was stopped, resulting in a system error. The drive where the SCIEX OS Data folder was stored was full, so backing up and clearing out older data allowed for data acquisition to proceed.

05/13/2019    SCIEX OS

Specifications for the SCIEX Pre-Assembled Capillary Cartridge for CE-SDS Applications

Specifications for the SCIEX pre-assembled capillary cartridge (part number A55625) are provided here.

05/03/2019    Capillary Electrophoresis

Using the Purity Score To Assess a Match to My Library Search Results in SCIEX OS Software

All peaks from both the unknown and library spectra are used to calculate the Purity Score, which is used to assess how well a compound matches an existing library compound. A high value indicates a high probability that the unknown spectrum has been correctly identified; a low value indicates the match is less certain.

04/23/2019    SCIEX OS

Calibration Correction Factor (CCF) for Laser-Induced Fluorescence (LIF) Calibration

The Calibration Correction Factor (CCF) for laser-induced fluorescence (LIF) calibration is the mathematical relationship between the fluorescence from a known concentration of the analyte and the associated signal detected by the instrument. An explanation of how it is calculated is provided in this article.

List of CE Capillaries with Pre-burned Detection Windows

CE capillaries with pre-burned detection windows are available for purchase; the dimensions and coating information for these products are listed here.

Plotting 32Karat Software Data Files that Have Been Exported as ASCII Files into Excel

To plot 32Karat software data into a graph/electropherogram format, open the ASCII file in Excel and then format the data as described.

Why Don't I get Hits when the Precursor Mass Tolerance Is Set to 0.01 Da when Searching SCIEX Libraries?

Searches of SCIEX libraries with the precursor mass tolerance set to 0.01 Da may not yield any hits. This is due to the fact that some of SCIEX libraries contain spectra that were acquired with inaccurate precursor m/z.

04/19/2019    SCIEX OS

Replacing the Logo Shown in My Report in SCIEX OS Software

To replace the logo shown in a report in SCIEX OS software after the results table is reviewed, click Reporting, then Create Report, and then save the Results Table. Click Replace Logo.

04/19/2019    SCIEX OS

The non-targeted peak searching algorithm determines which peaks are included for further library or formula finder searches in the Analytics mode of SCIEX OS Software, and the parameters that can be modified are described here.

04/17/2019    SCIEX OS

Installing the SCIEX OS Software CFR License

Save the CFR license file to the C:\ Program Files\Sciex\Sciex OS folder where the SCIEX OS license is located.

04/15/2019    SCIEX OS

Exporting reports and data graphic from the 32Karat method

Procedure to export reports (e.g. % area report, etc.) and data graphics (electropherograms with annotations) from the method.

User Role Not Assigned Correctly in SCIEX OS Software

To resolve the error "You do not have the correct SCIEX OS role permissions to access this product" in SCIEX OS software, the software needs to be opened under the Windows user login that the software was installed under.

04/05/2019    SCIEX OS

Coolant leak troubleshooting tips

The document provides troubleshooting steps for coolant leak issues (to determine where the leak is coming from).

Exporting PDA data from 32Karat into ASCII or AIA (.CDF) files

Procedure to export CE data files from the 32Karat software.

Understanding and optimizing signal-to-noise calculation in the 32Karat software

This document provides an overview of the S/N calculation and optimization in the 32Karat software.

Eliminating air bubbles in CEQ/GeXP gel cartridges

Centrifuge protocol to help get rid of air bubbles in gel cartridges that might get into the gel lines

How Is CEQ/GeXP Data Exported in the ABI Format?

This document explains how to export data files acquired with the CEQ/GeXP software into an ABI format for data reprocessing purposes.

Explanation of 32 Karat License Key Program and User License Types

32 Karat software requires a hardware license key to launch, and on older versions, a similar software license key is installed from a floppy disk.

Overview of the 32 Karat Software User Privileges

An overview is provided of each user privilege in the 32 Karat software that can be assigned or removed from the user.

How Does the Formula Finder Algorithm Work in Sciex OS Software?

The Formula Finder algorithm in SCIEX OS software tries to predict the possible chemical formula based on the MS and MS/MS spectrum using the precursor ion's mass accuracy, isotopic pattern and MS/MS fragmentation pattern.

04/02/2019    SCIEX OS

What Causes BioPharmaView™ Software To Stall when Processing Data or Running Batches?

BiopharmaView™ software will stall when processing data when more than one instance of the software is open or if there are some corrupted files in the processing queue folder in the BioPharmaView program files folder.

Uninstalling and Reinstalling SCIEX OS 1.x Software

This article describes how to uninstall SCIEX OS software and manually remove certain files in order to completely remove the software.

03/21/2019    SCIEX OS

Recalibrating TOF MS or TOF MS/MS Spectra in SCIEX OS Software

To recalibrate a TOF MS or TOF MS/MS spectrum or recalibrate samples in SCIEX OS software, open the data file in Explore mode, select process, and then select Recalibrate Spectrum or Recalibrate Sample.

03/21/2019    SCIEX OS

Exporting a Centroid Spectrum from SCIEX OS Software

To export a centroid spectrum from SCIEX OS software, load a data file and open a spectrum in explore mode; click Centroid Spectrum from Process drop-down list, and then select Export from the File drop-down list.

03/01/2019    SCIEX OS

Reporter 3.2: Adding Custom Columns to a Report Template

Custom columns can be added to a report template so that custom data values values can be read into a report created with Analyst® Reporter 3.2 (via Analyst software).

02/28/2019    Analyst Software

Changing Parameter Settings Options in Analyst® Software

Changing the options available for individual parameter settings in Analyst® software can be done by selecting Configure or Tune mode and then going to Tools > Settings > Parameter Settings.

02/28/2019    Analyst Software

How Many Modified Amino Acids and Modifications Can Be Added in PeakView® Software?

In general, the number of modified amino acids and modifications that can be added is unlimited in the PeakView® software.

02/28/2019    PeakView Software

Why is the Option to Sum Multiple Ions Grayed Out in SCIEX OS Software?

In order to use the Sum Multiple Ions option in the SCIEX OS software, the group name for each compound needs to be entered into the Group column.

02/28/2019    SCIEX OS

SCIEX OS 1.5 Software Launch Errors Overcome by Starting Clearcore2 Services

The Clearcore2 Service runs in the background for SCIEX OS 1.5 software. The service will need to be started manually in the Services section of the Control Panel if SCIEX OS will not launch.

02/28/2019    SCIEX OS

Maintaining LCMS Systems under Specified (Standby) Conditions Post-Acquisition in Analyst® Software

You can choose what happens to your system after the last sample in your queue has been acquired in Analyst® software.

02/28/2019    Analyst Software

Changing the Number of Decimals Displayed in Analyst® Software Calibration and Metric Plots

This is a set of instructions for changing the number of decimals displayed in Analyst® software quantitation metric plots and calibration curves. The default number of decimals leaves the significance so low that you can not reproduce the results shown in the results table. A warning is given to let customers know that Regedit is a dangerous utility.

Choosing the Peak Selection Criteria when Using SCIEX OS AutoPeak Integration Algorithm

This articles explains what type of peak selection criteria can be used with the SCIEX OS AutoPeak integration algorithm.

02/15/2019    SCIEX OS

Applying the Saturation Correction when Working with SCIEX OS AutoPeak Integration Algorithm

Saturation correction can correct for detector saturation effects. To make these changes in SCIEX OS software when working with the autopeak integration algorithm, select the saturation correction button in the method and specify the threshold value.

02/15/2019    SCIEX OS

Applying Results Table Column Settings to Another Results Table in SCIEX OS Software

To apply the custom result table column settings from one Sciex OS software results table to another, open a results table in the Analytics mode. Then set the custom column order that you want to be displayed by clicking the More button, and then choose Table Display Settings.

02/15/2019    SCIEX OS

What are the Library Search Algorithms in SCIEX OS Software?

When setting up a new processing method in SCIEX OS software's Analytics mode, there are three different library search algorithms that the user can select under the library search parameters dialogue: candidate, confirmation and smart confirmation search.

02/15/2019    SCIEX OS

Using the Same Peak Model for All Components in a Group with SCIEX OS AutoPeak Integration Algorithm

In order to use the same peak model for all components in a group in SCIEX OS software, the user must enable the Peak Selection by Group and Process by Group settings in the Project Default Settings before creating the processing method.

02/15/2019    SCIEX OS

BioPharmaView™ Software 2.x/3.0.x Cannot Open the Data for Subsequent Samples if the Data for the First Sample Is Corrupted

BioPharmaView™ software 2.x/3.0.x cannot open the data for subsequent samples if the data for the first sample is corrupted.

SCIEX OS 1.5 Installations on Windows 7 Require a TDC4 Driver Update

SCIEX OS 1.5 installations on Windows 7 require a TDC4 driver update. Please navigate to the installation folder for Sciex OS and select the Drivers folder. Inside should be a program xTDC4_driver_v1.1.0.exe which will remove version 1.0.3 and install 1.1.0.

02/08/2019    SCIEX OS

Bio Tool Kit Software License iNeeded for SCIEX OS 1.x and PeakView Software.

The Bio Tool Kit software can be activated within PeakView 2.x and SCIEX OS 1.x software but a separate software license is needed.

How To Move SCIEX Software License to a Different Computer

Description of the steps required to move an already activated SCIEX Software License from one computer to another.

01/28/2019    Software

How Do I Activate My SCIEX License Key?

To activate a SCIEX license key, log into www.sciex.com with your username and password. Navigate to https://sciex.com/support/activate-software and complete the required fields.

01/24/2019    Software

What Are the Considerations for Using Ion Pairing Reagents in My Mobile Phases?

Ion pairing reagents can greatly help with problematic chromatography, but any added ion pairing reagents also tend to stick to LC components and the column, as well as to the MS source, leading to signal suppression and diminished column performance. This article includes suggestions for a more successful experience when using ion pairing reagents and mass spectrometry.

01/24/2019   

How Is a MultiQuant™ Software Report Created in .CSV Format?

To create a report in MultiQuant™ software in .csv format, open a results table and then select Create Report under the File menu. Choose a comma delimited report template, and choose CSV as an output format.

01/24/2019    MultiQuant Software

What Are the Specifications of the Six-Protein Mixture Supplied with the iTRAQ® Kit?

Specifications of the six-protein mixture (PN 4348363) supplied with the iTRAQ® kit include the accession numbers of the proteins and their mass per tube (in µg and nmol).

01/09/2019    Academia Omics | Pharma CRO | iTRAQ Reagent

Tracking Pressure in Real-Time for an Exion LC System in Analyst® 1.7 Software

The ability to access a real-time report of pressure versus time trace is not available in the Analyst® software for the Exion LC systems. So far, this feature is only available for Agilent LC systems when using the Analyst Device Driver.

12/28/2018    Analyst Software

Changing the Orienatation of Peak Review Chromatograms in a Reporter Template

If the peak review chromatograms are showing in the wrong orientation on an Analyst® or MultiQuant™software report, the page orientation for the actual Word document template may be set to portrait rather than landscape.

To Prevent Contamination, Use Formic Acid Ampules

To prevent your samples from becoming contaminated, use formic acid from small volume ampules rather from a large bottle. Impurities can accrue when taking aliquots of formic acid multiple times from the same bottle, and these impurities can impact positive ion analysis especially.

12/28/2018    Standards and Reagents

Updating the Sample Information Column in MultiQuant™ Software Results Table

Updating the sample name column in MultiQuant™ software will fail and result in an error message if invalid characters are used in the added text. The Sample Name and Sample ID columns cannot contain the following characters: \ / : * ? " < > | = or . .

12/28/2018    MultiQuant Software

Filtering Library Results for Compounds in MetabolitePilot™ Software

Using the blue funnel icon in MetabolitePilot™ software in the top right of the Result Pane will help narrow the search results provided when evaluating information-dependent acquisition (IDA) data for possible compounds that correspond to potential metabolite.

12/28/2018    LibraryView Software

Compatibility of Standard MutliQuant™ Software Files with MultiQuant MD Software

This article describes the compatibility of standard, non-GLP MutliQuant™ software files with MultiQuant MD software.

12/28/2018    MultiQuant Software

MetabolitePilot™ 1.5 Software Upgrade License Requires Older 1.0 License as Base

When MetabolitePilot™ 1.5 software is launched, an error is received after reinstalling the software indicating that a demo version of the software license has expired. If the license being installed is a MetabolitePilot 1.5 upgrade license, it will always need to be installed alongside the original MetabolitePilot 1.0 license.

12/28/2018    MetabolitePilot Software

Analyst® Software Sub-projects Cannot Be Used with Custom Quant Table Settings

To create and apply custom results table settings in Analyst® software, sub-projects cannot be in use.

12/27/2018    Analyst Software

Changing the Extension on the Analyst® Software Data File Acquired to a Temp Folder

If an Analyst® software data file is acquired to a temp or a cache folder, the data file may not have the .wiff or .wiff.scan file extension name. The data file extension name must be changed to .wiff or wiff.scan when the user attempts to move the files to a new location.

12/27/2018    Analyst Software

How Is the ITC Parameter Accessed in Analyst® TF Software?

Changing the ion transmission control (ITC) parameter in Analyst® TF Software helps to assess if the QJet® ion guide on a Triple TOF® system needs to be cleaned. This article explains how to access the ITC parameter within the Analyst software.

12/27/2018    Analyst Software | QTOF Systems

Recommended NIST Library Processing Method Settings

The recommended library search settings when using the NIST library with MasterView™ or SCIEX OS software are listed here and include deactivating collision energy filtering.

Searching an EST or Other Nucleotide Databases in ProteinPilot™ Software

Searching an EST or other types of nucleotide databases in ProteinPilot™ software requires that the database be translated first.

12/27/2018    ProteinPilot Software

Sciex OS 1.3 Error "Services Cannot Launch" Due to Windows 10 Incompatibility

An error message is received when trying to launch SCIEX OS 1.3 that indicates that services cannot start. Ensure that the software is installed on a Windows 7, not Windows 10, operating system (OS). Only SCIEX OS version 1.4 and greater are compatible with Windows 10 OS.

12/27/2018    SCIEX OS

Resetting Root Directory to Analyst® Data Folder Restores Selexion® DMS Functionality

Resetting the root directory to the Analyst® Data folder restores Selexion® Differential Mobility Spectrometer (DMS) functionality and allows the hardware profile to activate in Analyst software.

What Are the Integration Types Used by Analyst® Software?

In Analyst® software, integration types by which the baseline is found and integrated when the peak is found are: baseline-to-baseline, valley, exponential skim, and exponential child.

12/27/2018    Analyst Software

Using Audit Trail and Security Features in MultiQuant™ Software Prevents Browsing to Other Project Folders

When using MultiQuant™ software with the audit trail and security features turned on, users will find that they are unable to browse to other project folder locations.

12/27/2018    MultiQuant Software

What Are the Peptide Sequences in the Six-Peptide Mixture (PN 4465940)?

The six-peptide mixture (part number 4465940) is used for the calibration of mass spectrometers. The kit contains the following six peptides and their mono-isotopic masses: bradykinin (2-9 clip) (904.4681), angiotensin I (1296.6853), glu1-fibrinopeptide (1570.6774), ACTH (1-17 clip) (2093.0867), ACTH (18-39 clip) (2465.1989), and ACTH (7-38 clip) (3657.9294).

Where Can LIF Emission and UV Bandpass Filters Be Ordered?

UV bandpass filters used with the fixed wavelength UV detectors or emission filters for the laser induced fluorescence (LIF) detector can be ordered from common optics companies such as Andover Optics or Newport Optics.

Using 32 Karat Software with a Corporate Network or Domain

32 Karat software can be used with a company network 1) to control user logins and permissions via a Windows operating system (OS) network domain controller and 2) to allow access to network printers and hard drives.

Windows Folder Permissions Needed for 32 Karat Software Pperation

A table of the needed security permissions that allow the 32 Karat software to operate correctly in a Windows operating system environment is shown.

12/26/2018   

Purpose of the Gel and Water Rinses in the SCIEX Capillary IsoElectric Focusing Shutdown Method

The purpose of the gel rinse followed by the water rinse in the SCIEX capillary isoelectric focusing (cIEF) shutdown method is to keep the capillary conditioned for use the next day.

12/05/2018    Capillary Electrophoresis

Primer Purity Requirements for Sequencing and Fragment Analysis Using the GenomeLab™ GeXP Genetic Analysis System

When ordering nucleic acid primers for use in either DNA sequencing or fragment analysis using the GenomeLab™ GeXP Genetic Analysis System or older CEQ genetic analyzers, be sure to select primers that--at the minimum--have been purified via solid phase extraction.

Common Issues when Using 32 Karat Software for Peak Integration

Peak integration with the 32 Karat software can be improved using the suggestions found here.

Improving Peak Resolution when Using Capillary Electrophoresis

Basic tips are presented here for improving the overall resolution of capillary electrophoresis (CE) separations.

SCIEX Software Activation with Offline Workstation

How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is not connected to the internet

11/19/2018    Software

SCIEX Software Activation with Online Workstation

How to activate Analyst, MultiQuant or SCIEX OS software with a computer which is connected to the Internet

11/19/2018    Software

Nomencature Used by BiopharmaView™ Software for N-Gylcan Names

BioPharmaView™ software uses predefined N-glycan structures (following the Ludger product names), or software users have the option to build their own custom modifications.

Charge Heterogeneity Buffer Vial Plate Map for Tech Bulletin IB-17031A

The plate map used in the SCIEX charge heterogeneity capillary zonal electrophoresis (CZE) assay will help guide users in setting up the method in the tech bulletin "Analysis of Monoclonal Antibody Charge Variants by Capillary Zone Electrophoresis" (Beckman Coulter IB-17031A).

How Do You Export a Library in LibraryView™ 1.0.1 Software?

The export of a library from LibraryView™ 1.0.1 software is described here.

Verifying if the Data File is Acquired with Checksum On or Off in Analyst® Software

After opening a data file in Analyst® software in Explore mode, select the Verify Checksum radio button; a new window will appear to indicate whether or not the checksum feature has been turned on for the data file.

11/09/2018    Analyst Software

Why Does the Checksum Invalid Error Appear when Processing Data in MultiQuant™ MD Software?

If the checksum invalid error appears while trying to process data with MultiQuant™ MD software, this indicates that the data was not previously acquired with checksum feature turned on in Analyst® MD software.

11/09/2018    MultiQuant Software

Exporting ProteinPilot™ Software Data to PRIDE (PRoteomics IDEntifications)

Exporting ProteinPilot™ software data to the PRoteomics IDEntifications (PRIDE) database requires the .group files be converted to XML files. ProteomeXchange fully supports both MS/MS proteomics and SRM data submissions. Other types of proteomics data, including ProteinPilot data, is also possible using the partial submission mechanism.

11/09/2018    Academia Omics | Software

Locating 66-Vial Plates in the Analyst® Software Plate Code Selection

Analyst® Device Driver supports 66-vial plates, but they are not initially found in the plate code selection of the Analyst software batch editor. To view this plate option, the rack code needs to be changed to 2 Drawer Plates and then the user can find both of the 66-well plate code options: 66VialGen PlateR and 66VialGenPlateC.

11/07/2018    Analyst Software

CDS Autocalibration without a HPLC System in the Analyst® Hardware Profile

Analyst® software will acquire data even if the CDS autocalibration system is activated without a HPLC system in the hardware profile.

11/02/2018    Analyst Software

Difference between Rapid and Thorough Searches in ProteinPilot™ Software

The rapid search and a thorough search settings in ProteinPilot™ software determine which parts of the search algorithm will be invoked and effectively how deep the sample will be searched to find the right answers.

How Can I Find the Computer ID on a Win 7 Operating System?

To locate the computer IDs (MAC or physical addresses) on a computer with a Windows 7 operating system, run the DOS command ipconfig/all, and a list of physical addresses be provided.

11/01/2018    Software

How to get the error log from inside a Shimadzu CBM for a VIERROR

Description of how to access the Shimadzu Web server which can help to diagnose errors

11/01/2018   

How to adjust, save and export the table settings in an Analyst Quantitation Table

Instructions how to modify (choose and adjust the visible columns, change the significant figures and notation), save and export an Analyst Quantitation Table.

Activating Analyst TF 1.7.1 Hardware Profile in Sim Mode

When running Analyst TF 1.7.1 in sim mode on a processing workstation, an additional driver, the Chronologic driver, must be downloaded and installed.

11/01/2018    Analyst Software

Importing a Library Package into LibraryView™ Software 1.3

To install a newly downloaded library package (.lpb file), select the import button in LibraryView™ software and then the correct file type.

10/22/2018    LibraryView Software

During PPG Tuning Some Mass-Charge Ratios Appear as NA

While tuning and calibrating the MS in Analyst® software, some masses in the calibration table are showing up as NA in the table despite clearly being present.

10/19/2018    Analyst Software

Permanent License Gives an Error Message of Expired for DiscoveryQuant™ Software

After launching DiscoveryQuant™ software, an error message is received indicating the software has expired even though a permanent license is installed.

10/19/2018    Software

Peak Labels from Analyst® Report Are Missing in MultiQuant™ Software Report

To add in the labels to reports generated in MultiQuant™ software, the tag for Peak Review has to be edited to show the Analyte_Peak_Name in the Label field.

10/19/2018    MultiQuant Software

Renaming Analyst® Software Data Files

Renaming an Analyst® software data file (.wiff and .wiff.scan) after forgetting to do so in the batch may prevent the data file from being reopened later.

10/18/2018    Analyst Software

MultiQuant™ Software Installation Error Due to Some Prerequisite Components Needing Reinstallation

A successful MultiQuant™ software installation requires that the SCIEX Reporter software and a .pdf reader program, PDF Factory, be installed prior to the installation of MultiQuant.

10/18/2018    MultiQuant Software

Recommended N-Glycan MALDI Sample Preparation Matrices for TOF/TOF Instruments

Depending on what type of N-glycan moiety that is being analyzed on a TOF/TOF system, refer to the table provided for recommended MALDI sample preparation techniques, matrices and acquisition methods.

10/18/2018   

Possible Non-Numerical Outcomes for MultiQuant™ Software Results Tables

Instead of a number, sometimes MultiQuant™ software returns a non-numerical result in the results table.

10/18/2018    MultiQuant Software

MultiQuant™ Reporter: System Out of Memory Error

When generating a report in MultiQuant™ software, an error appears: "System out of memory." To resolve this error, more memory can be added to the computer, a 64-bit computer can be used, or one of the two following workarounds can be used.

10/18/2018    MultiQuant Software

Ordering Foam Applicators for Cleaning a IonDrive™ QJet Ion Guide

The IonDrive™ QJet ion guide can be cleaned with an anti-static foam swab (part number 1017396 or 1017398).

10/18/2018    Mass Spectrometers

Will ProteinPilot™ 5.0.2 Software Function on a Windows 7 64-Bit System?

ProteinPilot™ 5.0.2 software has only been tested on Windows 10 SP1 64-bit with Microsoft Office version 2016.

10/17/2018    Pharma CRO | ProteinPilot Software

Using the 25 Micron ESI Electrode with the DuoSpray™ Source?

A 25 micron ESI electrode can be used with the IonDrive™ Turbo V source and the DuoSpray™ source.

Upgrading Analyst® Software Requires that Cliquid® Software be Uninstalled

Upgrading Analyst® software on workstations where Cliquid® software is also installed requires that Analyst be uninstalled as well as Cliquid software. After reinstalling Analyst software, then Cliquid can be reinstalled.

10/17/2018    Software

Can the Pressure Trace Be Monitored or Saved in SCIEX OS 1.4 Software?

Currently the pressure traces for many liquid chromatogram instruments can be monitored in real-time in the SCIEX OS software, but not be saved to a specific location.

10/16/2018    SCIEX OS

Compatibility of ProteinPilot Software 4.5 Beta with Microsoft Office 2016

ProteinPilot software 4.5 beta is not compatible with Microsoft Office 2016.

Installing Analyst® 1.7 Software on a Processing PC with Win 10

Described below are two procedures for installing Analyst® 1.7 software on Windows 10: 1) for a PC with a SCIEX-issued version of Windows 10 and 2) for a PC not purchased from SCIEX.

10/16/2018    Analyst Software

Formatting Analyte Names in an Analyst® Software Quantitation Method

When formatting analyte names in an Analyst® software quantitation method, they should not contain any dashes. A space should be used to separate analyte names and numbers in the quantitation method to correctly group analytes.

10/16/2018    Analyst Software

iTRAQ® Reagents: Can Samples Labeled with Both the 4-Plex and 8-Plex Kits Be Mixed?

The iTRAQ® Reagents chemistry for 4plex versus 8plex kits is described.SCIEX does not recommend mixing samples labeled with the reagents from the two separate iTRAQ® kits, 4plex and 8plex, due to the differences in the reagent chemistry.

10/16/2018    Academia Omics | Pharma CRO | iTRAQ Reagent

Enabling Hidden Folders in Windows 10 to Install an Analyst® Software License

Many users find that they cannot activate their Analyst® 1.7 software license file on a Windows 10 operating system because the folder where the license file is installed does not show.

10/12/2018    Analyst Software

Where Can I Get a New Registration Key for Analyst® Software?

If the registration key information for Analyst® software 1.6.x has been lost, navigate to https://sciex.com/analyst-and-analyst-tf-key-generator-registration to obtain a new one.

10/12/2018    Analyst Software

Which Amino Acids in the PepCalMix Are Labeled?

The PepCal Mix (P/N 5045759) contains 20 heavy-labeled peptides, with the heavy isotopes incorporated in the amino acids, K and R.

Plate Template Used for Tissue Imaging on MALDI TOF/TOF Instruments?

To use the Mass Spectrometry Imaging Starter Kit design by LaserBio Labs™, your tissue needs to be mounted onto a blank LC MALDI plate. This blank MALDI plate fits a 123 mm x 81 mm plate holder. A starter template is provided here to create a customized plate for MALDI data acquisition.

10/08/2018    Academia Omics

Where Are Report Templates Located for MasterView™ Software?

Report templates for MasterView™ software are located under the following root directory: C:\Users\Public\Documents\AB SCIEX\MasterView\Templates

10/08/2018    Software

Keeping a Nano LC/MS System Running after Sample Acquisition Is Completed

To keep a nano LC/MS system running after sample acquisition has completed, the LC/MS can be configured two different ways, assuming the Nano Eksigent 400 system is used.

Is the Analyst® or Analyst® TF Software Backwards Compatible?

The Analyst® or Analyst® TF software is only forward compatible.

10/08/2018    Analyst Software

Adjusting Integration Parameters to Exclude Peak Tailing Area in Analyst

Some analytes may display an undesirable amount of peak tailing, some of which may need to be excluded from the total integrated peak area. Adjusting the percent noise parameter in the IntelliQuan dialog may help to decrease the area of the peak included for integration.

09/06/2018    Analyst Software

How to Adjust Failed Ion Ratios in MultiQuant® Software

If the ion ratios are flagged in the MultiQuant® software results table, it usually indicates that there is some discrepancy in the integration of the peaks corresponding to the transitions used for that analyte group.

09/06/2018    MultiQuant Software

Which License Supports LibraryView™ 1.3 Software Installed with SCIEX OS 1.4?

LibraryView™ 1.3 software installed with SCIEX OS 1.4 requires a LibraryView 1.2 license.

08/31/2018    LibraryView Software

Removing Analytes from a MultiQuant Software Method (.qmethod)

To remove an unneeded analyte's MRM transitions from a MultiQuant software method, the quantitation method must be opened and the Delete Selected Rows function must be used.

Where Are the Queries Used with MultiQuant™ Software Stored?

MultiQuant™ software queries are saved in the following folder: C:\ProgramData\AB SCIEX\MultiQuant\Queries.

08/15/2018    Software

Licensing Information for the SWATH Acquisition™ MicroApp in PeakView® Software

When viewing license information in the PeakView® software Help menu, the SWATH™ acquisition microapp licensing info shows in the plug-ins list, but not in the PeakView License Report screen.

How to Create Custom Sample Trays for a CTC Autosampler

How to configure a CTC autosampler to use custom dimensions for use with alternative plates or vial racks.

08/15/2018   

Where Is the Data Stored from a Photo Diode Array (PDA) Interfaced wtih Analyst® Software?

When using a Waters photo diode array (PDA) with Analyst® software connected through an analog digital converter (ADC) connection, the data is stored in an Analyst data file (.wiff) and can also be viewed and processed in PeakView® software.

07/09/2018    Analyst Software

Where Is the Download for the SCIEX All-In-One 2.0 with NIST 2017 Library?

To download the SCIEX All-in-One HR-MS/MS library 2.0 and NIST 2017 MS/MS library (PN 5061635), go to the downloads page on the SCIEX website, and select the All-in-One library and the NIST library and download them both. Activate and install the licenses for each library.

07/09/2018    LibraryView Software

What Are the Options in Data Explorer Software To Improve Spectral Quality?

This document lists a couple of options on how to improve spectral quality using Data Explorer software 4.11

07/09/2018    Academia Omics

Where Can I Find Instructions for the Protein Preparation Kit?

Protein preparation instructions can be found on the SCIEX website at https://sciex.com/Documents/tech%20notes/Protein-Preparation-Kit-Protocol.pdf or https://sciex.com/products/standards-and-reagents/automated-protein-digestion-solution.

Can Report Templates from Analyst® or MultiQuant™ Software Be Used with SCIEX OS?

Report templates used previously with Analyst® or MultiQuant™ software should work with SCIEX OS, with the exception of MultiQuant templates that include a table query.

07/03/2018    SCIEX OS

Returning the Status Column to the Analyst® Software Queue Manager

To bring back the status column to the Analyst® software Queue Manager, right click in any column of the Queue Manager and select Column Settings.

07/03/2018    Analyst Software

Calculating Molecular Mass for Compounds with Isotopes in SCIEX OS

To calculate the molecular mass of compounds containing isotopes in SCIEX OS, select the Mass Calculators in the Explorer mode and then specify the chemical formula for the Mass Property tab. For isotopes, precede the chemical symbol with the weight of the isotope.

07/03/2018    SCIEX OS

SCIEX Trial License Key Not Received

The email address associated with your Sciex login must be verified when you request a trial license, otherwise you will not receive your trial license key by email.

07/03/2018    Software

Using Ammonium Fluoride (AMF) in an HPLC Solvent

Ammonium fluoride can be used in LC/MS applications as a mobile phase additive. It is recommended that only small concentrations as possible be used (around 0.2 mM).

07/03/2018    Mass Spectrometers

Protocol for Downgrading SCIEX OS 1.4 to 1.3

If downgrading from SCIEX OS 1.4 to 1.3 is required, follow the instructions below.

07/02/2018    SCIEX OS

Installing SciexOS 1.4 on a PC where Other SCIEX Software Was Previously Installed

SciexOS 1.4 uses the LibraryView™ Framework in the background to manage libraries and library searching. Older versions of the framework may be on the PC that can interfere with the installation of 1.4. Also, older version of Microsoft SQL server and .NET Framework can cause the installation process to fail. This article contains information on steps to take to remove older versions of the aforementioned tools.

07/02/2018    SCIEX OS

Does SCIEX OS 1.4 Support Queries?

SCIEX OS 1.4 does not support table queries in the Analytics component of the software.

07/02/2018    SCIEX OS

Transferring the Custom Column Settings from One MultiQuant™ Software Results Table to Another

To transfer the custom column settings from one MultiQuant™ software results table to another, select Column Settings and then export the .cset file. Open the new results table and then import the .cset file.

07/02/2018    MultiQuant Software

Activating a SCIEX Software Trial on Workstations that do not have Internet Connection

Activating SCIEX software on a computer without internet access can be made simpler by following these steps

06/21/2018    Software

LC Methods Not Opening in Analyst® Device Driver Software

Sometimes, the LC portion of a method in Analyst Device Driver (ADD) will not open successfully; yet the associated Analyst® software acquisition method file (.dam) is able to be opened, and the LC conditions can also still be viewed. To resolve this issue, avoid copying files between project folders or re-activate the hardware profile.

06/04/2018    Analyst Software

Exporting .T2D Files in Batch Mode from the Raw Data Spotset

To export .T2D files in batch mode from the raw data spot set on a MALDI plate, locate the Remote Data Access software in the program files and install the T2DExporter.

06/04/2018    Academia Omics | Pharma CRO

Convertingt MS data from .Wiff Format to a .Mgf File

To use different search engines/software, .wiff data must be converted to different format such as .mgf file before being able to submit the data for a search.

06/04/2018    Software

CAD Gas Setting Displays Incorrectly in the File Information for Analyst® 1.6.x or Higher

If a data file was acquired using simplified CAD gas settings and opened in the Analyst® software without the correct hardware profile active, the CAD gas setting in the file information will be displayed incorrectly.

06/01/2018    Analyst Software

Changing the Leak Sensor Detection Detector Threshold for a Shimadzu LC System

When a leak error is observed for a Shimadzu LC system but the channel is dry, it may be that the threshold for detecting a leak is set too low.

06/01/2018   

Firewalls Can Cause CloudConnect Connection Issues

The CloudConnect service is installed and runs in the SYSTEM security context, as opposed to PeakView which runs in user context. Some IT organizations block port 443SSL for SYSTEM level programs as a security measure.

06/01/2018    PeakView Software

Ion Ratios Are Not Calculated as Expected in MultiQuant™ Software

The ion ratio value was not showing correctly due to a blank sample being included as one of the calibrators in MultiQuant™ software.

06/01/2018    MultiQuant Software

Setting Up MRM Transitions if Q1 Mass Is Identical to that of a Second Compound

To set up a MRM transitions where the Q1 mass for one compound is identical to a second compound in Analyst® software, change the Q1 mass of the second compound by 0.1 -0.05 Da. After making this adjustment, the software will accept the duplicate mass for Q1.

Adding Negative Ion Mode Experiment Information to Analyst® Software Quant Methods

Adding a negative ion mode experiment to an Analyst® software quantitation methods can be done by opening an older quantitation method in Analyst and then using Save As to save a copy of the older method. The negative ion mode information can be added by toggling the Data Source options in that drop down menu.

05/31/2018    Analyst Software

Optimal CE Voltages for Peptide Analysis on TripleTOF® Systems

The collision energy (CE) and the collision energy spread (CES) values needed for peptide analysis (during protein IDA identification and SWATH® acquisition) can be optimized using Information in the rolling CE setting embedded in the Analyst® TF software.

To Install MultiQuant™ Software, Log into Windows as an Administrator

When installing a MultiQuant™ software license, an error message appears that says "The feature you are trying to access is unavailable. Cannot find license file/License File cannot be opened." To override this error, the software and license need to be installed while logged into Windows as an administrator.

05/31/2018    MultiQuant Software

Installing MultiQuant® Software Generates a .NET Framemwork Error

When installing MultiQuant® 3.0.2 software on Windows XP, an error message was received: "An error occurred while installing system components for MultiQuant. Setup cannot continue until all system components have been successfully installed."

05/31/2018    MultiQuant Software

Troubleshooting Peak Shape after Column Replacement

After replacing the analytical column, the analyte's peak shape changed, leading to ion ratio failures. Replacing the guard column resolved the peak shape issues.

05/31/2018   

Sample VB Code for Hours of Instrument Usage Information from Analyst® Software Audit Trail

Information about the hours of instrument usage can be obtained from the Analyst® software Audit Trail. Audit Trail data can be retrieved using IQuantAuditTrail interface methods NumEntries & GetEntry

05/31/2018    Analyst Software

Archiving and Purging MALDI TOF/TOF™ Data and Creating Database Backups

Described herein is a general procedure on how to archive/purge data from a MALDI TOF/TOF™ system, as well as how to back up data.

05/31/2018    Academia Omics | Pharma CRO

Starting an Analyst Software Data File (.wiff) with a Space

Can an Analyst® software data file name start with a space? The answer is yes. It is not a good practice to start the file name (.wiff) with a space, but Analyst software does allow the user to do that by using the format of "Subfolder name\ Datafile name" in the data column of the batch.

05/25/2018    Clinical | Analyst Software

Location of the Queue Option Tab in Analyst® 1.6 Software

To find the queue option tab in Analyst® 1.6.x software, click on configure mode and then click on the Tools menu, then select Settings and then click on Queue Options.

05/25/2018    Analyst Software

Can the Sample Injection Volume Be Displayed in an Analyst® Software Results Table?

Analyst® software results tables do not have the option to display the sample injection volume from the data file.

05/25/2018    Analyst Software

How to Adjust the Ion Ratio in MultiQuant Software

Where are ion ratios modified in a MultiQuant software quantitation method (.qmethod file)?

05/21/2018    MultiQuant Software

Error Message for National Instruments GPIB Driver Received during Analyst® Software Installation

To resolve the error message received for the National Instruments GPIB driver during Analyst® software installation, install the driver from the GPIB folder on the Analyst software installation disk manually.

05/21/2018    Analyst Software

MPX Softare Error: MPX Driver Is Not in the Active Analyst® Hardware Profile

To resolve the MPX software error "MPX driver is not in the active Analyst® hardware profile", remake the Analyst software hardware profile from scratch.

05/21/2018    MPX Software

MultiQuant™ Software Feature Unavailable Error Message

When installing a MultiQuant™ 2.0 software license, a MultiQuant Feature Unavailable error message is received. Installing the correct version of MultiQuant will resolve this issue.

05/21/2018    MultiQuant Software

SCIEX Registered Software Webpage Lists All Recently Activated Licenses

The SCIEX Registered Software webpage (https://sciex.com/support/registered-software) lists all recently activated licenses.

05/21/2018    Software

How Is Peak Asymmetry Caluclated in Analyst® Software Quantitate Mode?

Peak asymmetry is calculated in Analyst® software Quantitate mode using the formula ((Peak end time) - (Retention Time)) / ((Retention Time - (Peak start time)).

05/21/2018    Analyst Software

How to Add Compound Information to LibraryView™ Software 1.1

To add information about a compound to LibraryView™ software 1.1, expand the Compounds list in the Manage pane to begin adding the compound name, and then follow the directions provided.

05/21/2018    LibraryView Software

The Analyst® Device Driver 1.3 Release Notes

The Analyst® Device Driver 1.3 Release Notes are attached. Please consult this guide for the new features and changes from the previous versions.

05/21/2018    Analyst Software

Unable to Create Project in Analyst® Software

If a project folder is not accessible in Analyst® software, then the root directory must be set to C:\Analyst Data\Projects\. Additional projects and subprojects are set up under this root directory.

05/21/2018    Analyst Software

Dionex: Is the DCMS Link 2.10 and 2.12 Compatible with Win7 32- and 64-bit?

The DCMSLink is not validated to work with a Win 7 operating system (OS) as stated in the Dionex release notes.

05/16/2018    Analyst Software

Analyst® 1.7 Software Launch Error: No Such Feature Exists

If the license error "No such feature exists" appears when launching Analyst® 1.7 software, install the license file to the C:\ProgramData\AB SCIEX\Analyst\License folder resolve the issue.

05/16/2018    Analyst Software

What Are the Reasons for Hybrid Electrodes Probe Blockage?

Common issue reported with hybrid electrodes probes.

05/15/2018    Academia Omics | Mass Spectrometers

Converting .Xml Templates to .Docx Reporter Templates for Analyst® 1.5 to 1.6 Software

To convert the .xml files to .docx reporter templates for Analyst® software, the templates must first be updated to .docx. This is done by using the AB SCIEX Reporter Template Converter located in the following directory: C:\Program Files\ABSCIEX\Reporter Template Converter\Template Converter.

05/15/2018    Analyst Software

Creating a Peptide Library in Skyline with a ProteinPilot™ 5.0 Software .Group File

If a user installs ProteinPilot™ 5.0 software with Skyline, old and new group files will not be able to be opened because the converter has changed. An error message will be displayed when building peptide libraries while importing a ProteinPilot group file.

05/15/2018    ProteinPilot Software

Error in SWATH MicroApps: Window Widths below 4 Da Are Not Supported

This error will appear if the SWATH configuration file is not edited to allow for window widths below 4 Da.

05/15/2018    Academia Omics

Installing a License for BioTool Kit in PeakView® Software 2.2

BioTool Kit software is a software module within PeakView® 2.2 software that needs to be activated by a separate license. To install a BioTool Kit license, open PeakView 2.2, navigate to the Help menu, and select BioTool Kit Activation.

05/15/2018    Bio Tool Kit Software

Network Acquisition and Processing of Analyst® Software Data Files and Time Stamps

When data files acquired with Analyst® software are saved to a network server, does the time stamp on the data come from the local machine or the network server? After processing data in the Analyst project folder residing on the network server, the results files were also saved on the network server. Does the data time stamp come from the local machine or the network server?

05/15/2018    Analyst Software

Avoiding an Invalid Transition List Format Error when Building a Method in Skyline for Analyst® Software

When building a MRM method in Skyline for use in Analyst® 1.6.1 software, the following error may appear: "Invalid transition list format. Failure parsing numeric value".

05/15/2018    Analyst Software

Shimadzu Pumps Do Not Start when Selecting Equilibrate in Analyst® Software

Selecting Equilibrate in Analyst® software does not always turn on the Shimadzu LC pumps. To get the LC pumps to respond, users must follow a specific start up procedure and recognize when the system has gone into standby mode.

05/14/2018    Analyst Software

Data Files Should Be Copied at the Project Folder Level in Analyst® Software

The best way to copy Analyst® software data and method files is to copy and paste at the project level.

05/14/2018    MultiQuant Software

Access to Path Is Denied Error when Installing License

When installing a Sciex software license, an error message appears that says the license was not sucessfully installed and the access to the path C:\Program Files\AB Sciex\.... is denied. This error message indicates that 1) the user doesn't have sufficient privileges to access the Program Files, or 2) the license file needs to be placed in correct location in the Program FIles manually.

05/14/2018    Software

How Is Quantitation Information Imported into an Analyst® Software Batch?

To import updated quantitation information into the batch, export the batch file as a text file from Analyst® software and edit the information in Excel.

05/14/2018    Analyst Software

How Are Graph Axis Setting Changed in Analyst® Software?

To change the x- and y- axis settings for a chromatogram in Analyst® software, navigate to the Tools menu, select Settings, and then the Appearance Options menu. The x- and y-axis options are in the Other Graph Options tab.

05/14/2018    Analyst Software

Analyst® Software Freezes when the Hardware Profile Includes a LC System

In situations where Analyst® software will only launch acquisition methods successfully with a MS-only hardware profiles, but crashes when a Shimadzu LC autsaompler with a rack controller is added to the hardware profile, check to see if the Rack Controller is checked on the autosampler portion of the hardware profile.

05/11/2018    Analyst Software

Integrating Peaks from a DAD or UV Chromatogram in Analyst® Software

Analyst® software Quantitate mode can be used to integrate peaks from DAD or UV chromatograms that were acquired during an LC/MS experiment.

05/11/2018    Analyst Software

Data File not in Expected Location in Analyst® Software Project Folder

Ensure that the correct project folder is selected in Analyst® software prior to data acquisition. Data will be acquired to whichever folder is showing in the horizontal menu bar.

05/11/2018    Analyst Software

Downloading Software from the SCIEX Website Requires the Most Current Browser

To successfully download a trial license or software from the SCIEX website, your browser needs to be up-to-date.

05/11/2018    Software

Does the BioTool Kit MicroApp Require a Separate License in PeakView® Software?

The BioTool Kit MicroApp features cannot be accessed in PeakView® software unless a separate license is installed alongside the PeakView® license.

Molecular Ion Not Appearing during Compound Optimization

Adding mobile phase to the analyte or increasing its concentration during compound optimization may help improve ionization.

05/11/2018   

Waters Driver and SCIEX Software Compatiblity Guide

Please consult the attached guide, "Waters tested Sciex Configuration Guide," to determine if a Waters driver will work with a particular version of Analyst® software. Please make sure Waters UPLC firmware is compatible with the driver pack or ICS version.

05/08/2018    Analyst Software

High Mass Cooling in Analyst® Software during Full Scans

The High Mass Cooling functionality was introduced to Analyst® software to minimize the negative effects of very high RF voltages on the quadrupole rod arrays. It is used only on certain instruments (5500, and 6500 series in low mass mode only) in order to slightly extend the usable mass range while maintaining optimal ion transmission and sensitivity.

05/04/2018    Analyst Software

Release Notes for Analyst® TF 1.7.1 Software with Components for LC Devices

Analyst® TF 1.7.1 Software with Components for LC Devices Release Notes are attached. Please consult this guide for the newly added support for the NanoCell Interface, Exion LC series of devices and the Analyst Device Driver.

05/03/2018    Analyst Software

Analyst® Device Driver 1.3 Tutorial

The Analyst® Device Driver 1.3 Tutorial is a guide for the device driver usage and contains troubleshooting tips.

05/03/2018    Analyst Software

Analyst® 1.7 Software License Error: Cannot Find License File

After activating the Analyst® 1.7 software license and saving it to C:/ProgramData/AB SCIEX/Analyst/License, the software would still not activate and error message -1,359 was received. Retyping the license file name to "Analyst1.7.lic" resolved the issue.

05/03/2018    Analyst Software

How to Update Retention Times in Sciex OS

To update the retention time (RT) of an analyte in Sciex OS, open a results table consisting of grouped components with different RTs, and then follow the instructions provided below.

05/03/2018    SCIEX OS

Protocols for Protein Precipitation in Samples before Using iTRAQ® Kits

To prepare samples prior to iTRAQ® reagent labeling, use the following protocols.

05/01/2018    Academia Omics | Pharma CRO | iTRAQ Reagent

Setting Up a Scheduled Ionization Method in Analyst 1.7 Software

The scheduled ionization feature can be used to reduce the mass spectrometer downtime by decreasing the risk of contamination. To set up a scheduled ionization method in Analyst® 1.7 software, follow the instructions below.

05/01/2018    Analyst Software

Does Analyst® 1.7 Software Support the Windows Long-Term Service Channel?

Windows10 and Analyst® software are not supported by the Windows long-term service channel.

04/27/2018    Analyst Software

Analyst® 1.7 Software License Error: No Such Feature Exists. Feature: Analyst.acquisition

To resolve the Analyst® 1.7 license error "No such feature exists. Feature: Analyst.acquisition", the license key made need to be replaced. This error occurs when a processing license is installed on an acquisition workstation.

04/12/2018    Analyst Software

Analyst® 1.7 Software Installation Guide

The Analyst® 1.7 Software Installation Guide is attached. Please consult this guide before installing this version of Analyst software on your PC.

04/10/2018    Analyst Software

Overlaying Two or More Extracted Ion Chromatograms (XICs) in Analyst® Software Explore Mode

To overlay extracted ion chromatograms (XICs) in Analyst® software Explore mode, click on the first XIC, then select Overlay in the Explore menu, and then select the second XIC. The second XIC will now appear in the same screen as the first XIC.

03/22/2018    Analyst Software

Upgrading MultiQuant™ Software from version 3.0.1 to 3.0.x

To upgrade to MultiQuant™ software from version 3.0 to version 3.0.1, 3.0.2 or 3.0.3, the following instructions should be followed.

03/22/2018    MultiQuant Software

Setting up a Rack Changer in Sciex OS Simulation Mode

To set up the RackChanger in Sciex OS in simulation mode, go to Devices under Configuration mode. Select Add and choose Integrated System and follow the directions below.

03/22/2018    SCIEX OS

Incorrect Peak Area Sum when Using Sum Multiple Ions Feature in MultiQuant Software 3.0.1

The Sum Multiple Ion feature in MultiQuant™ 3.0.1 software can be used to sum the fragment ions of a precursor ion. Using this feature does not create a resulting sum that matches the result when Excel is used to calculate the sum of the XIC peak areas for the same fragment ions. The reasons are explained here.

03/22/2018    MultiQuant Software

Where Can I Download SCIEX Software?

Full versions of many our software programs can be downloaded from the SCIEX website at https://sciex.com/software-support/software-downloads.

03/16/2018    Software

MultiQuant™ Software's sMRM Feature May Require an Extension License

If an installation of MultiQuant™ software will not process sMRM data, an extension license may be need to be installed.

03/16/2018    MultiQuant Software

Where Is the License for a LibraryView™ Software Library Installed?

If the LibraryView™ software library cannot be viewed through the software after installing it, the location of the library license needs to be checked. It should be installed to C:\Program Files\AB SCIEX\LibraryView\bin.

03/16/2018    LibraryView Software

Selecting a New Tab in the Waters Method Editor Resolves LC Method Creation Error in Analyst® Software

An error results when selecting the ACQ-BSM tab when creating an LC method using the Acquity Method Editor accessed through Analyst® software. It can be resolved by selecting any other tab in the method editor screen.

03/16/2018    Software

ProteinPilot™ 5.x Software: Incorrect Result Output for Instrument Names in the Group File

ProteinPilot™ software uses the incorrect mass spectrometer name in its group file output file. When a TripleTOF® 5600 system was selected, the group file contains the name QSTAR® Elite instead for system information. This causes the wrong results to be output; if the incorrect instrument name is used, then the incorrect tolerance settings are applied.

Separating Two Experiments Acquired within One Period in Analyst® Software

Data from two or more experiments acquired within one period in Analyst® software can be separated by opening a data file in Explore mode and double clicking the green arrow.

03/15/2018    Analyst Software

Restoring Calibration Reference Tables in Analyst® Softare

To restore a calibration reference table in Analyst® software, copy the TuneData.tun file over to the current API instrument folder/Preferences folder.

03/15/2018    Analyst Software

For MS3 Experiments, Why Are Two Peaks Adjacent to the Ion of Interest Also Selected?

If AF2 (a parameter describing the amplitude of the resonant excitation field) is very large, then off-resonant excitation will begin to increase the kinetic energy of neighboring m/z ions.

03/15/2018    QTRAP Systems | Analyst Software

Analyst® 1.7 Software Installation Error in Windows 10

Upgrading from Analyst® 1.6.3 to Analyst 1.7 software in a Windows 10 environment will cause an installation error, and Analyst 1.7 software will not launch. Analyst 1.7 with Hotfix 1 must be installed alone, and previous versions of Analyst software cannot also be installed concurrently.

03/14/2018    Analyst Software

Analyst® Software Scheduled MRM Acquisition Failure Due To Unprogrammed Diverter Valve

Scheduled MRM acquisition methods created in Analyst® software may fail to start if there is a diverter valve in the hardware profile. Ensure that that valve has a time table program or that it is removed from the method's hardware profile.

03/14/2018    Analyst Software

Analyst® 1.7 Software Patch for Windows 10 Update 1709 Installation Error

When installing Analyst® 1.7 software with Hotfix 1 and the patch for Analyst 1.7 for Windows 10 Update 1709, the following error message was received, "You must have Analyst 1.7 software installed to install Analyst 1.7 Patch for Windows 10 Update 1709."

03/14/2018   

Shimadzu 30AC Autosampler External Rinse Method Definitions in Analyst® Software

On the Shimadzu 30AC autosampler, the external rinse function flushes the needle's exterior using a solution that is pushed to the rinse port by the rinse pump. When building an LCMS acquisition method in Analyst® software, the rinse method definitions can be accessed through the Flow Channel Reference radio button under the Autosampler tab.

03/13/2018   

MPX™ Software Batch Stoppage due to Daylight Savings Time Shift

If the computer clock updates for daylight savings time while MPX™ software is submitting a batch, data corruption and batch stoppage can occur. The clock must be set up so that automatic updates to the time do not occur.

03/12/2018    MPX Software

Creating Windows User Groups for Analyst® Software Security Configuration

Windows User Groups are established for each role established in the Analyst® software security configuration.

03/08/2018    Analyst Software

Adding User Groups to the Analyst® Software Secruity Configuration

The steps below describe how to add user groups into the Analyst® software security configuration.

03/08/2018    Analyst Software

MultiQuant™ Software Error: Currently Running in Another Windows Session

To resolve the MultiQuant™ software error "Currently running in another Windows session on this computer. Switch to the other session and close the software", shut down Analyst® and MultiQuant software and services under both accounts, and then relaunch software under one account.

03/07/2018    MultiQuant Software

ProteinPilot Software Datafile Cannot be Searched because two files are acquired under same file name

Searching for ProteinPilot software files using Windows Explorer cannot be done because there are two files acquired under the same file name. This is a long known issue for all ProteinPilot versions that only one file per file name can be searched using ProteinPilot software.

Is It Possible To Set the Y-Axis to a Fixed Value in Analyst™ Software?

When reviewing data in the Analyst™ software Explore mode, the y-axis for the signal intensity cannot be set to a fixed value to compare results from one run to another. But this can be done in Quantitate mode while reviewing peaks in a results table by selecting Tools -> Settings -> Peak Review Settings and typing in the Intensity under Automatic Zooming -> Y axis units.

03/06/2018    Analyst Software

How to Generate MRM Ratios in Analyst Software

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

BioPharmaview™ Software: Simultaneous Analysis of Disulfide Bridges and Cysteine Modification Not Possible

Disulfide bond mapping in BioPharmaView™ software is described in the user guide. However, creating a disulfide bridge table in addition to analyzing cysteine modifications simultaneously is not described and cannot be done.

MarkerView™ 1.2.1 and 1.3 software and PeakView® 2.2 software can import T2D files generated on the TOF/TOF™ series of instruments.

02/26/2018    Academia Omics | MarkerView Software

How Many Vials of Each iTRAQ® Reagent Are in the Multiplex Kit?

Each iTRAQ reagent multiplex kit (PN 4352135) contains 5 vials of of the following iTRAQ reagent labels: 114, 115, 116, and 117.

02/26/2018    Academia Omics | Pharma CRO | iTRAQ Reagent

How Does the Quadrupole Transmission Function in the TripleTOF® Systems Work?

For TOFMS, all ions pass through Q1 in RF mode. In general, Q1 and Q2 perform "hops" over the mass range, ensuring an appropriate envelope of masses is passed into the TOF analyzer. The general explanation found here for the QSTAR® systems can also be used to explain TripleTOF® systems as well.

01/31/2018    QTOF Systems

Finding the Pulser Frequency in an Acquisition Method Built in Analyst® TF Software

In general, the pulser frequency is automatically calculated for a given mass range in the method editor using the Analyst® TF software. To see the pulser frequency value, follow the directions below.

01/12/2018    Analyst Software

ChemoView™ Software Error after Data Processing: Programmatic Access To Visual Basic Project Is Not Trusted

Chemoview™ software error after data processing "Programmatic access to Visual Basic project is not trusted" can be resolved by turning on the access to the VBA object model from any automation client.

01/12/2018    ChemoView Software

Two Methods for Finding the Number of Points Collected across a Peak in Analyst® Software

Determining the number of points across a peak in Analyst software can be done two ways: 1) View - Graph Information, and 2) Tools - Settings - Appearance Options - Other Graph Option - Yes (with scan number ) under Chromatogram.

01/11/2018    Analyst Software

Directly Transferring Data from MultiQuant Software to a LIMS System

Data Innovation is a third party company that can set up a direct connection from MultiQuant to a LIMS system. http://www.datainnovations.com/support/driver-downloads

12/22/2017    MultiQuant Software

Maximum Setting for Collision Energy (CE) during Compound Optimization

The maximum value that can be used for collision energy (CE) during compound optimization in Analyst® software is 130, even though the CE value can be set to 180 in the parameter settings.

12/22/2017    Analyst Software

Viewing Real-Time PDA or UV-Vis Data in Analyst® Software when Employing a Shimadzu AAO

Viewing real-time photo-diode array (PDA) or UV-vis data is not possible in Analyst® software when employing a Shimadzu diode array or UV-vis detector.

12/22/2017    Analyst Software

Why Can't I Open Analyst® Software when My Security Role Is Set to Supervisor?

If a user has the security role of supervisor in Analyst® software, then he/she can override a screen lock or logout of the software--but only if the Analyst security configuration is set to Mixed Mode.

12/22/2017    Analyst Software

Converting Sciex OS WIFF2 Files to the MzML and MzXML Format

The Proteowizard tool (http://proteowizard.sourceforge.net/downloads.shtml) for MzML and MzXML conversion has been updated to work with the new WIFF2 files that are produced by SCIEX OS 1.2 and 1.3.

12/22/2017    Analyst Software

Integrated Syringe Error Message Recieved while Using Manual Tune Mode in Analyst® Software

While running Analyst® software in Manual Tune mode during compound optimization, an error message is received: "The current sample cannot be run because the syringe pump has stalled. The syringe plunger may be stalled in the syringe barrel." To resolve this issue, move the syringe holder back and clear error. If this doesn't work, replace the syringe, or if still needed, reset the MS.

12/21/2017    Mass Spectrometers

What Curtain Gas Setting Should Be Used on the QTRAP® 6500 System?

The QTRAP® 6500 system has a limit of 50 psi for the curtain gas. Curtain gas settings should not be higher than 40-45 psi.

12/21/2017   

Shimadzu Autosampler Rack Must Be Seated Correctly for Analyst® Software to Acquire Samples

Acquisition and equilibration errors in Analyst® software signalling a Shimadzu LC controller error may be the result of the autosampler rack not seated correctly in the autosampler housing.

12/21/2017    Analyst Software

Detuning an Acquisition Method in Analyst® Software

If the signal seems to be saturating during acquisition on a Triple Quad™ 5500 system using Analyst® software, one option is to detune the acquisition method by using non-optimized collision energy values for the MRM transitions.

What Version of LibraryView™ Software Is Needed for a Win 7 64-bit System?

Install LibraryView™ software version 1.0.2 for use with Windows 7, 64-bit systems.

12/21/2017    LibraryView Software

Which Software License Is Used for LibraryView™ 1.2 Software Installed with SCIEX OS 1.3?

When installing LibraryView™ 1.2 software alongside SCIEX OS 1.3, use a LibraryView 1.0 license, PN 5022277.

12/21/2017    SCIEX OS | LibraryView Software

Replacing a Trial License with a Permanent License

When opening a program, an error message may appear that indicates that the license has expired, even when a permanent license is thought to be installed. For these cases, the trial license may still be installed in program files and will need to be removed and replaced with the permanent license.

12/21/2017    Software

Configuring Analyst® Software for Email Notification of Audit Trail Events

Users can configure the Analyst® software to send an email message if there are three log on errors within one day. This email notification is available only if the workstation is in Integrated Mode or Mixed Mode.

12/21/2017    Analyst Software

Clearing a Manual Tune Error Message in Analyst® Software

If the syringe runs dry while doing direct infusion, a manual tune error may disrupt compound optimization in Analyst® software manual tune mode, requiring an LC/MS system reset.

12/21/2017    Analyst Software

Will SCIEX Have a Windows 10 Compatible Analyst® and Mutiquant™ Software Version?

Analyst 1.7 software and Multiquant 3.0.3 software are now available, and both of these versions are Windows 10 compatible.

12/20/2017    Software

Adding Acquity Plate Definitions into Analyst® Software

To add the definition of the Acquity 96-well, 1-mL plate (using ANSI-96well1mL.plate file) to Analyst® software, a plate definition file must be acquired from Waters.

12/20/2017    Analyst Software

Separating Concatenated .wiff Files in Analyst® Software

To separate concatenated .wiff file sets, a script called Make Subset File is used. This script might have limitations for Analyst® and Analyst TF software because it depends on the experiments in the file (i.e., the script does not work for IDA methods). The script is found on the Analyst TF software CD in the folder \Extras\Scripts\Make Subset File.

Can the SWATH™ Acquisition Variable Window Calculator v 1.0 Be Used with All TripleTOF® Systems?

SWATH™ acquisition software and the variable window methods will work on the TripleTOF® 4600, 5600 and 6600 systems, but Analyst® TF 1.7 software must be installed.

12/15/2017    Analyst Software | SWATH Acquisition

SCIEX Website Login Requires that Your Email Address Is Verified

After creating your login for the SCIEX website, you will be asked to verify your email. Click on the link in the webpage that appears after your account is created or in the email sent to you by SciexNOW to activate your online account with SCIEX.

12/14/2017   

Analyst® Report Template for LIS: Why Won't the LIS System Read Past the First Line of Data?

If a CSV output file generated using the Analyst® software report template for LIS systems contains any cells with no data values, then the LIS system may not read past the empty cell. To ensure that the LIS reads the whole output file, each cell in the CSV file must contain a value of some kind.

12/14/2017    Analyst Software

Which Calibration Standards Can Be Used for Intact Protein Analysis on TripleTOF® and X500 Systemss?

An APCI calibrant solution for the SCIEX X500B System and a mAb standard from Waters were compared. Results show that the mass to charge ratio for the calibrant solutions remain constant regardless of the charge state. Secondly, for readings over 500 m/z, the calibration is highly linear for the X500B system.

12/14/2017    Academia Omics | Pharma CRO | QTOF Systems

Injection Error Dectected after Sample Start: Shimadzu LC Controller Device Fault

If an injection error is detected after starting samples in the Analyst® software queue, and everything else seems fine with the LCMS system, check that the Shimadzu autosampler rack is seated correctly in the autosampler housing.

12/14/2017    Analyst Software

Column Name Conflict Error when Running MultiQuant™ Software Reports

The error message "The column name 'ion type' conflicts with an existing column" appears when running MultiQuant™ software reports. This occurs when the report uses a query, but gets interrupted midway through the processing, leaving several additional columns in the MultiQuant results table.

12/14/2017    MultiQuant Software

MultiQuant™ Software Error: "Update Column Settings Failed"

The MultiQuant™ software error "Update Column Settings Failed. Object reference not set to an instance of an object" is due to a memory leak problem, which can be quickly fixed by closing and reopening the program.

12/13/2017    MultiQuant Software

Patch for the Analyst® TF Software 1.7.1 Noise Sync Signal Issue

This patch addresses a defect in Analyst® TF software 1.7.1 that causes occasional acquisition failures resulting in the warning “Noise failing sync signal ignored" being reported in the application log file (ATF-665, -TDC error).

12/13/2017    Analyst Software

Importing *.xlsx Files to Build Batches in Analyst® Software

Importing *.xlsx files to build batches in Analyst® software requires Microsoft Office 32-bit to be installed, although its not recommended to use the 32-bit version of Office on a 64-bit Win 7 operating system. SCIEX recommends that the following file formats be used instead: .xls, .csv and .txt.

12/13/2017    Software

Opening SCIEX OS Results Tables Containing UV and MS Data

To open a SCIEX OS results table created using a data file (.wiff2) with both UV and MS data, both data types must be selected for processing when creating the quantitation method in Sciex OS. Otherwise, an error message is received "Error. Cannot be empty, Parameter name: experiments" when opening Sciex OS results tables after they are created.

12/13/2017    SCIEX OS

Equilibration Issue with Exion and Photo Diode Array (PDA) and Analyst® Software

When an Exion LC system with a photo diode array (PDA) detector will not communicate with the Analyst® software, reactivate the hardware profile and restart Analyst services.

12/11/2017    Analyst Software

Acquity AAO Service Did Not Start

Steps are provided for editing the service properties of the AAO file to resolve the error "Cannot start service from the command line or a debugger." Editing the service properties will direct the AAO file to reopen in the event that it closes.

12/11/2017    Software

MultiQuant™ Software's Audit Trail and Security Feature Requires a Base and an Extension License

When installing MultiQuant™ software with the audit trail and security extension license, the license installs successfully, but MultiQuant software does not launch. Instead, a -5 error code appears and the error message displayed reads, "This feature is not licensed. It cannot be used." MultiQuant requires a base license to be installed alongside its audit trail and security extension license.

12/11/2017    MultiQuant Software

How Are Retention Times Updated in MultiQuant™ Software Processing Methods?

There are two ways to update retention times (RTs) in MultiQuant™ software quantitation methods. One way is temporary and the other way is permanent.

12/11/2017    MultiQuant Software

What Files Must Be Backed Up before an Analyst Software Reinstall?

Back up the API Instrument project folder in the Analyst Data folder prior to any reinstall or upgrade of the Analyst software. To upgrade an older version of Analyst, remove and back up the Analyst Data folder and any remaining short cuts on your workstation. Reboot the PC and install the new version of the software.

License Not Supported Error Appears after Installing MultiQuant™ Software

After a new MultiQuant™ software installation, the error message, "License not supported" is displayed.

12/11/2017    MultiQuant Software

Where Can I find Safety Data Sheets (MSDS) or Certificates of Analysis (CoA)?

To find the Safety Data Sheets and Certificate of Analysis for Sciex reagents, navigate to https://sciex.com/tech-regulatory?safetyTerm=4406127&safetyLanguage=English-United+States

12/11/2017    Standards and Reagents

Tips and Tricks for Cation-Exchange Chromatography for the iTRAQ® Protocol

The manual injection procedure for the iTRAQ® protocol requires a 22-gauge syringe with a 2-inch needle (purchased separately). This article lists some tips and tricks on how to set up the syringe when using cation-exchange columns for samples treated with the iTRAQ reagent.

12/08/2017    Academia Omics | Pharma CRO | iTRAQ Reagent

Updating Quantitation Method Files in Analyst® and Multiquant™ Software with a New Analyte

This article describes which method files need to be updated in Analyst® and MultiQuant™ software when new compounds are added to the method.

12/08/2017    Analyst Software

Analyst Regression Equations

This document summarises the equations used by Analyst to calculate the regression curves used for Quantitation.

12/04/2017    Analyst Software

How Does the Score in the Peptide Sequencing Section of BioPharmaView™ Software 2.1 Work?

Each peptide is displayed in a table after processing the peptide digest in BioPharmaView™ software. A score is given to each peptide after it is compared to the theoretical proteolytic digest.

Where can I download MaxQuant software?

MaxQuant software is a quantitative proteomics software package designed for analyzing large-scale mass-spectrometric data sets. It supports all main labeling techniques like SILAC, di-methyl, TMT and iTRAQ, as well as label-free quantification.

12/01/2017    Academia Omics | Software

Where Can I Find a Column Part Number from Eksigent?

The provided link lists all micro and nano columns including nano chip columns.

Why Doesn't the Recalculated Concentration in Excel Fit the Calculated Concentration in Analyst?

If I check the calculated results from Analyst for calculated concentration in Excel, the results do not match exactly. Why does this happen and how can I avoid this?

PPG Reference Peak List Table Is Missing when Tuning and Cannot Be Opened

To view the mass calibration peak lists in Analyst® software while using the manual tuning mode, go to the Tools menu and select Settings-Appearance options-Miscellaneous-Show Mass calibration peak list.

11/22/2017    Analyst Software

How Do You Setup a Solenoid or Solvent Selection Valve on a Shimadzu LC?

This article describes how to setup a FCV-11 AL valve for a Shimadzu LC system.

11/22/2017    Clinical

Reasons for Data File Processing Failure with the Data Converter Version 1.3 Beta

What are the potential issues listed which can cause the SCIEX MS data converter version 1.3 beta to not work correctly?

11/22/2017    Academia Omics | Pharma CRO | Software

MultiQuant™ Software Cannot Launch with an sMRM Extension License Only

Two licenses need to be installed when using an sMRM extension license: One must be the MultiQuant™ software basic license, and the other is the sMRM extension license.

11/22/2017    MultiQuant Software

Can MutliQuant™ 2.x and MultiQuant 3.x Software Be Installed Side-by-Side on the Same PC?

Only one version of MultiQuant™ software can be installed on a PC. Two separate versions of MultiQuant cannot be installed side-by-side.

11/22/2017    MultiQuant Software

What Default URL Is Used for Configuring the Mascot Server with ProteinPilot™ Software?

Configuring the Mascot server from the ProteinPilot™ software requires the default URL to be used.

When I change integration in an Analyst® result table manually or automatically I always have to click apply and accept. Is there a possibility to make this process easier

The Audit Trail settings in Analyst software enforce that all manual integrations have to be Accepted. If you do not require the Audit Trail you can turn off this requirement by setting the audit map to No Audit Trail.

11/15/2017    Analyst Software

Activating Markerview 1.2.1.1 Software Requires an Activation Key Code, Not a License File

Installing Markerview 1.2.1.1. requires an activation key code, not a license file. Software activation key codes can be obtained by emailing metabolomics@sciex.com.

11/14/2017    MarkerView Software

What Is Skyline Software and What Data Types Does It Work With?

This article includes a general description of the features of Skyline software and the possible data formats from SCIEX instruments that work with Skyline.

Acetic Acid Is Needed To Prepare the PepCalMix Peptides in the SWATH® Acquisition Performance Kit

This article describes the experimental issues when formic acid is used to prepare the PepCalMix for the SWATH® Acquisition Performance Kit instead of 5% acetic acid.

Where Can I Download Skyline Software ?

This article includes the link to a free download of Skyline software.

How Do You Obtain a Token for ChemSpider Software?

The Formula Finder Settings panel in Sciex OS software requests a ChemSpider security token after selecting the ChemSpider Service. To obtain a token, users will have to register on the ChemSpider website.

11/08/2017    SCIEX OS

What Is the Full Amino Acid Sequence of BETA-GALACTOSIDASE in the LC/MS Peptide Calibration Kit?

The full amino acid sequence for beta-galactosidase is provided in the FASTA file format. The kit (part number 4465938) contains one vial of beta galactosidase digest (625 pmol/vial).

What Is the Latest Nano Acquity Driver that Is Supported by Windows 7 OS (32 and 64 bit)?

The latest Nano Acquity driver that supports the Windows 7 operating system (both 32- and 64-bit) is the ACQUITY UPLC M-Class Driver Pack version 1.55.

10/31/2017    Analyst Software

How Is the Software Protection Service in Windows 7 Disabled?

The steps for disabling the Software Protection service in Windows 7 are provided here.

10/31/2017    Software

Resetting an Agilent Infinity II LC System after Receiving an ADD Error

This article explains how to reset an Agilent Infinity II LC system after receiving an ADD error by clearing the configuration.

10/31/2017    Analyst Software

Where Are the MPX™ Driver Software Event Logs Located?

To locate the MPX™ Driver software event logs, navigate to the MPX Driver folder in Program Data and locate the Log folder.

10/31/2017    MPX Software

Location of the Audit Trail Archives in Analyst® Software

When the Instrument Audit Trail or a Project Audit Trail in Analyst® software reaches 1000 records, a final record stating that the file has been archived is added. The audit trail is automatically saved in the Project Information folder with a name indicating the type of audit trail and the date and time.

10/31/2017    Analyst Software

What is the Format of the Login for Analyst Software?

The format of the login for Analyst® software can be in two formats: 1) type in the user name and select the domain from the drop down or 2) log in using user@domain.org or DOMAIN\UserName.

10/31/2017    Analyst Software

How Is a Special Acquisition Account Setup in Analyst® Software?

To select an Acquisition Account Mode, navigate to the Security Configuration menu in Analyst® software and in the Security tab select the type of account, Client or Special Acquisition Administration Account.

10/31/2017    Analyst Software

How Is an Ion Library Created in Analyst® Software?

To create an ion library in Analyst® software, each MS or MS/MS spectrum needs to be opened and then added to a small existing database.

10/30/2017    Analyst Software

How to delete Results Table Settings in Analyst Quantitation Mode

Where to find the 'remove' button for the results table settings

10/23/2017    Analyst Software

Injection volume must be a positive value

If the Regional Settings in an Acquisition Computer with Analyst® Software is not set to US English , this can course the Error message: "Batch not submitted-Injection volume must be a positive value" during submitting a Batch.

Explore Mode - Extract Ions - Overlay Multiple Panes Automatically

Where to find the settings for automatically overlay panes when extracting multiple Ions.

Part Number for the Tubing from the Exion/Shimadzu Autosampler to the Column Oven?

The tubing connecting the Exion/Shimadzu autosampler to the column oven is stainless steel with connectors and is coated with flexible plastic (600 mm x 0.1 mm). This part can be obtained can be obtained directly from Shimadzu (PN 228-53184-91) or from the online SCIEX store.

10/23/2017    ExionLC AC | ExionLC AD

Manage Mode Is Greyed Out in ChemoView 2.0.3 Software

After logging into ChemoView software, only the Process pane was accessible. The Manage pane was greyed out. This was resolved by changing all users in Analyst software to administrators in the Security Configuration mode.

10/20/2017    ChemoView Software

How Is a Hardware Profile Created in Simulation Mode with an Eksigent 4.x and Analyst TF Software?

Description of the steps to place the Eksigent software in the AAO system of the Analyst® software and how to run it in simulation mode.

MultiQuant™ Software Would Not Launch after License Installation

MultiQuant™ software may not launch after installation, and a -1 license installation error may appear. To resolve this issue, the user needs to be logged into Windows as an administrator and have full access to the program files on the C: drive.

10/17/2017    Software

How Do You Set Up for Manual Tuning Using Tee Infusion?

Before setting up your manual tuning method for source/gas optimization, your MS instrument must be set up for continuous infusion with high LC flow.

10/13/2017    Mass Spectrometers

Scheduled MRM™ Data with Polarity Switching Not Opening in MultiQuant™ Software

Scheduled MRM™ methods with polarity switching must use the same sMRM mode--either basic or advanced--but not both in the same Analyst® software acquisition method.

10/04/2017    MultiQuant Software

MultiQuant™ Software v2.0 Will Not Launch with a 2.0 License

The MultiQuant™ software 2.0 license will not launch the 2.0 version of MultiQuant software. Instead, MultiQuant software 2.0.2, 2.1 or 2.1.1 must be installed.

10/03/2017    MultiQuant Software

How Is the SWATH® Acquisition Variable Window Calculator Excel Sheet Used?

This article includes step-by-step instructions on how to calculate variable windows for your SWATH® acquisition experiment and how to generate the input and output list.

A summary of the findings from an investigation into the identity of background Ions found in -ve mode electrospray mass spectrometry with suggestions to help minimize their impact on analysis.

10/02/2017    Mass Spectrometers

Lost sensitivity on your Triple Quad or QTRAP You may need to optimize your CEM detector parameter.

This article explains how to resolve the issue of low sensitivity on a Triple Quadrupole or QTRAP instrument due to an incorrect CEM value by manually optimizing the CEM detector parameter in the Analyst software

09/29/2017    QTRAP Systems | Triple Quad Systems

How Do I Obtain a Trial License for SCIEX Software?

To download and obtain a licensed trial for a SCIEX companion software, navigate to https://sciex.com/products/software#tryfree and select the software that you would like to try.

09/27/2017    Software

Incorrect Argument Error when Creating MultiQuant™ Software Results Table

To resolve the Incorrect Argument error that occurs when creating a MultiQuant™ software results table, data should be transferred within the Analyst® software project folder to a new PC and not as individual .wiff and .wiff.scan files.

09/26/2017    MultiQuant Software

Polarity Switching Is Not Supported in Analyst® Software Versions below 1.6

To run sMRM methods with polarity switching, Analyst® software 1.6 or greater must be used.

09/26/2017    Analyst Software

Can I add a Compound to My Library with MasterView™ instead of LibraryView™ Software?

LibraryView™ software, but not MasterView™ software, must be used to add a compound to an existing library. You can use MasterView software to import other libraries or a new library, but not a new compound from a newly acquired MS/MS spectrum.

09/26/2017    MasterView Software

Sciex OS Software Startup Always Defaults to License Activation Screen

Every time Sciex OS software is launched, the license activation screen continues to appear with all fields blank, even though previous launches of the software indicate that the software license was installed successfully. Reinstalling the software as an administrator using a local admin user will resolve this issue.

09/20/2017    SCIEX OS

Analyst® Software Error: Failed to Write Method to Datafile Caused by Symantic Antivirus

Disabling the Sonar technology in the Symantic Antivirus program prevents the Analyst® software error "Failed to write method to datafile".

09/18/2017    Analyst Software

Antivirus Software Symantec v12.x Interferes with Data Acquisition with Analyst® Software

Antivirus software can disrupt data acquisition with Analyst® software, Analyst TF and related SCIEX software programs such as DiscoveryQuant™, Cliquid®, LightSight®, Reporter, and MultiQuant™ software. This article provides guidance on how to configure the antivirus software to avoid conflicts with Analyst® software that could cause data acquisition issues.

09/18/2017    Analyst Software

Where Can I Find Out If My Software Upgrade Is Free or a Paid Upgrade?

To determine if your software upgrade is complimentary, check the SCIEX webpage, Software Product Lifecycle at https://sciex.com/software-support/software-support-policy.

09/14/2017    Software

What is the IP Address Used by the Uniprot Server to Submit a ProteinPilot™ Software 5.x Search?

This article describes the website links that are being used to submit a ProteinPilot™ software (v 5.x) search.

Should I Install Windows Updates on My Acquisition Computer?

Windows updates should not install automatically on your acquisition workstation, but once you receive notification that there are new updates, these can be installed when Analyst® software is not acquiring data.

09/12/2017    Software

What is my Source Exhaust and how does it work?

Description of the Source Exhaust components and common requirements to maintain optimal performance

09/12/2017    Mass Spectrometers

How Do You Select Root Directory for a Workgroup in Analyst® Software 1.6.3?

To select a root directory for a workgroup in Analyst® software 1.6.3, the workstations should be removed from the workgroup and then re-added.

09/11/2017    Analyst Software

Is ProteinPilot™ Software 5.0.1 Compatible with Windows 10?

Is ProteinPilot™ Software 5.0.1 compatible with Windows10? No, it works only with Windows 7, Service Pack 1, 64-bit.

Installing and Activating a New License for a Computer not Connected to the Internet

If a software license needs to be installed on a computer that is not connected to the internet, look up the computer IDs for that computer, copy them, and then activate the license on an internet-connected workstation.

09/11/2017    Software

ProteinPilot™ Software 5.0: What Are the Criteria for Including a Peptide in the Feature Tab?

The general filters for peptides are listed here. These are applied through the feature tab in ProteinPilot™ software.

How Are SWATH™ Acquisition Files Recalibrated?

The procedure for recalibrating a SWATH™ acquisition file is outlined here.

Where Can I Find Micro HILIC Columns to Separate Hydrophilic Peptides?

Hydrophilic interaction chromatography (HILIC) columns for separating hydrophilic peptides can be found in the SCIEX column catalog (https://sciex.com/products/hplc-products/microlc-products/micro-hplc-columns).

08/03/2017   

How Can an Ion Library Group File Generated by ProteinPilot™ Software Be Uploaded to BaseSpace?

The procedure for uploading a group file generated by ProteinPilot™ software is described here. The group file is used as an ion library in BaseSpace and is uploaded using the CloudConnect MicroApp within PeakView® software.

08/03/2017    Academia Omics | PeakView Software

PeakView® Software 1.2 License Code Replacement

PeakView® software 1.2 displays an error message indicating that the license is about to expire. The software needs to be reinstalled, and new license code obtained.

08/02/2017   

License File Was Not Emailed when AID Key Was Entered without Dashes

When activating a software license key online (at https://licensing.sciex.com/), the license key number must be entered with dashes after every fourth character in the AID- key (e.g., AID-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx).

07/14/2017   

How Are Simple Queries Created in MultiQuant™ Software?

Simple queries can be created in MultiQuant™ software by selecting the Create Simple Query option in the Process menu. The formula can then be entered into the Create Query File screen.

07/14/2017    Software

What Is a Fraglet.exe Error when Running ProteinPilot™ Software 5.0?

A "Fraglet-exe-Error" can have many causes within the ProteinPilot™ software. In some cases, this error is caused when installing ProteinPilot on an incompatible operating system.

What Is the Function of the Collision Gas (CAD) on QTRAP® System Instruments?

The various functions of the CAD gas are described for the QTRAP® System instruments and the different scan types.

How Is a ChemSpider Software License Activated within PeakView® Software?

The software activation procedure is described step-by-step for ChemSpider, which needs to be activated within PeakView® software's FormularFinder feature.

07/10/2017    Pharma CRO | PeakView Software

Setup Cannot Continue Error when Installing MultiQuant™ Software

The MutliQuant™ software installation error "Setup cannot continue until all system components have been successfully installed" indicates that a Windows 10 operating system is present and the software must be reinstalled on a Windows 7 system.

06/29/2017    MultiQuant Software

MultiQuant™ Software Will Not Launch after Installation

After successfully installing MultiQuant™ software and launching the software for the first time, the license activation screen does not appear and the license can not be installed.

06/21/2017    MultiQuant Software

How to Save Application and System event logs in Windows 7

The Windows event logs often contain crucial data about the performance of SCIEX software. Follow these steps to save your system and Application event logs so that they can be analysed by the SCIEX support team.

06/15/2017    Software

Where Can I Find More Information about Software IQ/OQ Testing Plans?

More information about software validation services can be found by emailing complianceservices@sciex.com.

06/09/2017    Pharma CRO | Software

How Can Concentrations above the ULOQ be Flagged in MultiQuant™ Software?

Concentrations above the ULOQ can be flagged in your MultiQuant™ software results table by setting up the Upper Limit of Calculated Concentration in the Quant method.

06/08/2017    Software

How Can I Recover My Software License after Replacing My Hard Drive?

If your computer hard drive dies and you need to recover your license files, please contact SCIEX technical support for assistance.

06/08/2017    Software

Considerations for Bin Sizes when Creating a TOF Acquisition Method in Analyst® TF Software

What does "bin size" mean and what is the rule of thumb for setting bin sizes when setting up acquisition methods for a TOF MS system in Analyst® TF software.

06/07/2017    ProteinPilot Software

Can You Print a Quantitation Method in MultiQuant™ Software?

MultiQuant™ software does not have an option to print the quantiation method. However, the quantitation method can be copied or exported as text file into Excel and printed.

06/06/2017    Software

How Can the Data from Two Experiments Acquired within One Period Be Separated in Analyst Software?

Data from two or more experiments acquired within one period can be separated by opening a data file in Explore mode and double clicking the green arrow.

06/06/2017    Clinical | Software

How Are the Correct Solenoid Valves for a Shimadzu Pump Added to an Analyst Hardware Profile?

The solenoid valves for Shimadzu pumps can be set up by editing the hardware profile and changing the pump configuration.

06/01/2017    Software

How Are Calibration and Integration Parameters Defined in MultiQuant™ Software?

The default integration parameters are defined in the User Integration Defaults or User Units & Calibration Defaults under the Edit menu in MultiQuant™ software. These settings should be established before creating a quantitation method.

06/01/2017    Software

MultiQuant™ MD Software Will Not Launch from Desktop

MultiQuant™ MD software will not launch if the Analyst® software security setting is set to Integrated or Mixed mode. To keep these security settings, launch MultiQuant from the Companion Software mode in the left-side vertical menu in Analyst. Otherwise, change the security settings to single-user mode to open MultiQuant MD from the desktop.

06/01/2017    Software

After Activating My Software License Key, the License File Was Not Emailed to Me

After the software license key was activated online at the SCIEX website, the license file was not emailed to the registered email address. This occurs when the email address is not entered correctly.

06/01/2017    Software

How to merge Analyst Acquisition Methods

Where to find, how to install and to use the 'Merge MRM' Script in Analyst.

05/31/2017   

Why is my Graph Selection Window in SCIEX OS transparent?

Why is my Graph Selection Window in SCIEX OS transparent?

05/31/2017   

How to deal with the Analyst User Registration Pop-Up-Window

When freshly installed and not yet registered Analyst asks in a pop-up-window for a Registration Key. Here is shown where to get it.

05/31/2017    Analyst Software

How to Add a new User into LibraryView™ Software

This article explain how to add a new User into the Security Database of LibraryView™ Software 1.0.x. Users need to be added to open the Software.

05/31/2017    LibraryView Software

Recommendations for Computer Maintenance for Analyst® Software

What types of computer maintenance can be done to ensure that Analyst® software runs smoothly?

05/26/2017    Analyst Software

Trouble Importing Sample List into Lipidomics Workflow Manager Project

In order to import a sample list successfully into Lipidomics Workflow Manager 1.0.5, the following software must be also installed: Microsoft Office 2010 and Access 2007 Runtime.

05/25/2017    Software

Unable to Create Reports in MultiQuant™ Software

The Create Report option in MultiQuant™ software is not showing in the File menu because the incorrect version of Microsoft Office is installed.

05/17/2017    MultiQuant Software

Why Does My Area Ratio Show as N/A in MultiQuant™ Software?

Area ratios that give a value of N/A in MultiQuant™ software are likely due to an internal standard not being integrated or only being designated, but not assigned, to an analyte.

05/16/2017    MultiQuant Software

The Report Option Is Missing from the MultiQuant™ Software File Menu

When the Report option is missing entirely from the MultiQuant™ software File menu, check that the version of Microsoft Office installed is correct.

05/04/2017    MultiQuant Software

Intact protein script for TripleTOF™ instruments

This knowledge article summarizes when to use the intact protein script in

PA800 How To - Cartridge Removal

Video demonstration of Cartridge Removal on the PA800 system

PA800 How To - Capillary Storage

Capillary Storage Details for PA800 System

PA800 How To - Installing the Cartridge Aperture

Procedure for Installing the Cartridge Aperture on the PA800 system

PA800 How To - Cartridge Removal Rebuild Reinstallation

Procedure for Cartridge Removal Rebuild Reinstallation on PA800 System

LC Pumps Continue to Run after a Batch Ends in Analyst 1.6.3

If a batch completes, but the LC pumps never turn off, the Max Idle Time may need to be adjusted in Queue Options.

04/27/2017    Analyst Software

How Do You Convert a Non-scheduled MRM Method to a Scheduled MRM Method in Analyst?

Converting a non-scheduled MRM method to a scheduled MRM method requires that the retention time of each transition is updated in the Analyst software method.

04/25/2017    Analyst Software

Considerations when Installing or Upgrading to Sciex OS 1.2

When upgrading to Sciex OS 1.2 from version 1.0, the software for Sciex OS 1.0 must be uninstalled prior to installing Sciex OS 1.2. LibraryView Framework version 1.1 must be removed as well. Certain companion software must be removed as well, and installed again after Sciex OS 1.2 is installed.

04/25/2017    Software

HPLC cycle time can be decreased by using inject ahead mode on autosamplers. This article explores the effect of using this mode and defines how the same result can be achieved without the requirement for inject ahead mode.

04/21/2017   

How Are Submitted Batches Rearranged in the Analyst Queue?

Batches can be rearranged in the Analyst software queue using the Move Batch option. In the Move Batch window, drag the batch to be moved to the desired location to rearrange.

04/17/2017    Analyst Software

Can a Precursor-ion IDA Experiment Be Performed on a SCIEX TripleTOF System?

None of the SCIEX TOF instruments, 5600, 5600+, 6600, X500R, or X500B, can do a precursor ion IDA experiment.

04/13/2017    Analyst Software | QTOF Systems

How can you edit a query file extension?

Editing a query file extension requires renaming of the file name.

How Are the Method Parameters Chosen for Autocalibration Samples in the X500 Series?

Method parameters for autocalibrations submitted in SCIEX OS batches are automatically chosen from the sample after the autocalibration.

How do I store iTRAQ® labeled peptides?

Store iTRAQ® reagent labeled peptides at -20 or -80 degrees Celsius. Avoid having the peptides undergo multiple freeze/thaw cycles. iTRAQ-labeled peptides can degrade over time.

04/07/2017    Academia Omics | Pharma CRO | iTRAQ Reagent

Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.

04/07/2017    Software

Analyst: How is the limit on the number of samples in the queue increased?

The limit on the number of samples added to the queue for a run can be adjusted using the Max. Num. Waiting Samples setting in the Queue Options menu.

04/04/2017    Analyst Software

Re-installing a MPX License by Dropping the License Directly into the Program Files

If MPX driver software does not accept a license saved on the desktop during the license installation process, drop the license into the MPX bin folder in the program files.

03/31/2017    MPX Software

Adjusting Settings on a New Installation of DiscoveryQuant Software to Trigger a Run

A new installation of DiscoveryQuant (DQ) software was not triggering injections with an Acquity UPLC. Adjustments to the settings in DiscoveryQuant included changing the autosampler type, building a new hardware profile, re-establishing communications between the LC and MS, specifying a plate location, and disabling the Look Ahead injection type.

03/31/2017   

Agilent Infiniti II HPLC System and SCIEX 6500+ Systems

When an Agilent Infinity II HPLC system is experiencing difficulty communicating with a SCIEX QTRAP or TripleQuad 6500+ System while running samples, this procedure must be followed for bringing the HPLC system online and building methods.

03/24/2017   

MALDI TOFTOF: Can I calibrate using a linear mode acquisition method in batch mode?

When calibrating a linear mode acquisition method in batch mode the software reports that a reflector mode acquisition method is required in order to use the batch mode.

03/24/2017    Academia Omics | Pharma CRO

How is a new hardware profile created that contains a 6500+ system and an Agilent Infinity II LC system that is using the Analyst Device Driver software?

03/23/2017    Triple Quad 6500

Why doesn't a TrEMBL FASTA file work for a ProteinPilot search?

This is a known issue, and the TrEMBL database is not recommended for use with ProteinPilot software. The TrEMBL database is automatically annotated and not reviewed and could contain redundancies in terms of protein sequences, protein ascension numbers, etc.

Tuning Solution for the X-Series QTOF System Is Used Too Quickly

Quickly depleted tuning solution for the X-Series QTOF System is usually caused by leaks in the Calibrant Delivery System (CDS) plumbing.

03/21/2017   

Where is the method found that is created during automatic compound optimization?

When several compounds are optimized in Analyst 1.6.3, one method is created with all the MRM transitions included. The final MRM method created contains all compounds and is present at the bottom of the compound optimization report.

03/20/2017    Analyst Software

Troubleshooting retention time shifts and variable pump pressure

Instructions for performing flow tests on Shimadzu Nexera and EXION AD HPLC pumps and troubleshooting common causes of inadequate pump flow.

03/20/2017    ExionLC AD

Power cycling the PC, HPLC, and MS to solve communication problems

A power cycle can be performed on LCMS components to solve communication problems.

03/20/2017    Mass Spectrometers

How many processing cores will my ProteinPilot Software use?

The number of processing cores used by ProteinPilot Software is defined by the license file and the physical capabilities of the instrument.

Computer error: Raid status was degraded

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

03/09/2017   

Replacing the Sciex OS 1.0 License with a Sciex 1.2

Sciex OS 1.0 users must upgrade to Sciex OS 1.2. New license keys for Sciex OS 1.2 were distributed to Sciex 1.0 users. After removing the Sciex OS 1.0 license from C:/program files/Sciex/Sciex OS, the Sciex OS 1.2 license file should be installed from the desktop using the license activation screen in the Sciex OS 1.2 software.

03/06/2017   

Low Virtual Memory Warning

If you receive warnings that your virtual memory is low youll need to increase the minimum size of your paging file

12/07/2016    Software

ProteinPilot error fraglet.exe CHEMICAL EXCEPTION

ProteinPilot error fraglet.exe CHEMICAL EXCEPTION

How to Import LibraryView Snapshot File

If reinstalling software or moving to different hardware it may be required to import a snapshot file.

How do I search an EST or other nucleotide database

How do I search an EST or other nucleotide database

How do I modify the parameter translation file for mass tolerance and threshold for reporting iTRAQ ratios

Mass tolerance and threshold values for reporting iTRAQ ratios can be tuned by editing a configuration file.

10/07/2016    Academia Omics | iTRAQ Reagent

Can ethanol be substituted for isopropanol when performing iTRAQ protocol for 4Plex and 8Plex

Can ethanol be substituted for isopropanol when performing iTRAQ protocol for 4Plex and 8Plex

10/07/2016    Academia Omics | iTRAQ Reagent

Can the Eksigent Nano III ion source fittings withstand the back pressure when using a UPLC

Can the Eksigent Nano III ion source fittings withstand the back pressure when using a UPLC

10/07/2016    Academia Omics | NanoLC 400

Ekspert™ 400 LC system – Change the mobile phase

How to change mobile phase on Ekspert™ 400 LC system

10/07/2016    Academia Omics | Pharma CRO | NanoLC 400

Late elution of peaks on Eksigent nano Tempo Classic

Late elution of peaks on Eksigent nano Tempo Classic

10/07/2016    Academia Omics | NanoLC 400

Why are the peaks centroided in ProteinPilot Group files

Why are the peaks centroided in ProteinPilot Group files

How do I reset values or changes made in the ParameterTranslation file or ProteinPilotDataDictionary file in ProteinPilot

It may be required to reset the values within these files if they have been manually adjusted incorrectly.

Can I convert t2d files to mzxml file using 4700 data

Can I convert t2d files to mzxml file using 4700 data

10/07/2016    Academia Omics

Can I use the Proteinpilot SW with 4700 data

Can I use the Proteinpilot SW with 4700 data

fraglet.exe not wellformed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71

ProteinPilot gives the error fraglet.exe not wellformed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71

Can I reverse the flow on my Eksigent Nano Chrom XP C18 column when experiencing high back pressure

Can I reverse the flow on my Eksigent Nano Chrom XP C18 column when experiencing high back pressure

What solutions should be used for the nano 2D LC Eksigent pump seal rinse and the Autosampler wash

What solutions should be used for the nano 2D LC Eksigent pump seal rinse and the Autosampler wash

10/07/2016    Academia Omics | NanoLC

Why it is not recommended to open Audit Trail Archives with Newer Versions of Software

Opening/reading Audit Trail files should only be performed with the same version of Analyst software as they were acquired.

09/04/2016    Analyst Software

Troubleshooting Amplifier Reset

An Amplifier Reset alert simply means that the pump has emptied and refilled. As the pump has a finite volume then this refilling is expected if running for a long time or at a high flow rate. Note that an Amplifier Reset is an Alert not an Error. If an Amplifier Reset occurs the pump will refill and continue to pump at the programmed rate. An Amplifier Reset will not cause the sample batch or queue to stop. If an Alert message appears indicating that an Amplifier Reset has occurred the first step is to determine if this is a natural reset or not. In the following section are steps described how to determine the cause of an amplifier reset.

09/04/2016    Academia Omics

How to find Computer ID for Windows XP

Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.

09/04/2016    Software

Analyst Projects dropdown is not in alphanumeric order

Analyst Projects drop down provides project list in what appears to be an unordered list

09/04/2016    Analyst Software

Ekspert 400 AS3 Error Message Pump volume is not sufficient to run LC method without a restroke.

Ekspert 400 AS3 Error Message Pump volume is not sufficient to run LC method without a restroke

09/04/2016    Academia Omics

How to remove unused template definitions from DiscoveryQuant 2.1.x

This document explains how to remove unused template definitions from the DiscoveryQuant Analyze setup window

09/04/2016    Pharma CRO | DiscoveryQuant Software

Is it possible to export the correlation coefficient r from a MultiQuant results table

This article gives a guidance how to export the correlation coefficient r from a MultiQuant results table. Only Available in MultiQuant Version 3.0.1.

09/04/2016    MultiQuant Software

How to install ProteinPilot 4.5b and upgrade from ProteinPilot 4.0 to ProteinPilot 4.5b

This procedure describes the removal and install of ProteinPilotTM software 4.5b in great detail.

Analyst Software Batch Editor Could not open the batch data DAB Sever Error

When importing a Analyst batch from a file the import fails and the Error Could not open the batch data DAB Sever Error is displayed

09/04/2016    Analyst Software

How to print from XIC Manager in PeakView

Description of the methods which can be employed to print from XIC Manager.

Ekspert 400 AS3 Error Message ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED

Ekspert 400 AS3 Error Message ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED

09/04/2016    Academia Omics | NanoLC 400

Login into LibraryView software failed

Login into LibraryView Software failed.

09/04/2016    LibraryView Software

Manually Integrate script is installed but when running the script an error message appears saying that the script is not installed.

On Windows 7 I have the Manually Integrate script installed but when running the script an error message appears saying that the script is not installed.

07/08/2016    Analyst Software

Do you have any recommendations for the inclusionexclusion lists size for the Analyst TF 1.6 software

Do you have any recommendations for the inclusionexclusion lists size for the Analyst TF 1.6 software

07/08/2016    Analyst Software

Chromatograms do not populate on printed reports linked image cannot be displayed

When generating large reports after a number of Chromatograms the box will be filled with the text linked image cannot be displayed

07/08/2016    Analyst Software

Scheduled MRM not supported in Multiquant you do not have the required license to open files containing scheduled MRM data

Scheduled MRM not supported in Multiquant you do not have the required license to open files containing scheduled MRM data

07/08/2016    MultiQuant Software

MarkerView 1.2.1 error Could not get method information for A1_MS_1.t2d when trying to download data

MarkerView 1.2.1 error Could not get method information for A1_MS_1.t2d when trying to download data

07/08/2016    Academia Omics | MarkerView Software

How Do I Configure Analyst® Software for Network Acquisition

Network data acquisition can be very useful for data integrity backup security and access purposes. This walkthrough explains how to configure Network Acquisition using Analyst Software.

07/08/2016    Analyst Software

Does the Mascot.dll script work with Analyst 1.6 on a win 7 PC

Defines the issues and workarounds required to use the script.

07/08/2016    Academia Omics | Software

ConfigUpdater.exe will not update instrument firmware.

Issues with Windows Firewall preventing ConfigUpdater from updating instrument firmware via Ethernet connection.

07/08/2016    Software

Reporter gives an error on Analyst 1.6.x workstation Unexpected error has occurred

Reporter gives an error on Analyst 1.6.x workstation Unexpected error has occurred

07/08/2016    Analyst Software

Reporter 3.0 or 3.2 Cannot see tags for formatting.

Word does not show the tags content controls used for creating reports.

07/08/2016    Analyst Software

Can I use the Eksigent 3.12.1 software on a Win7 64 bit PC

Instructions on how to configure Windows 7 for use with the Eksigent 3.12.1 software.

07/08/2016    Academia Omics | NanoLC 400

No report styles available in Cliquid 3.2

Unable to create or select report styles after a fresh install of Cliquid 3.2.

07/08/2016    Cliquid Software

Working with LibraryView software during data collection by the Analyst software causes the Analyst software to stop acquiring data.

Working with LibraryView software during data collection by the Analyst software causes the Analyst software to stop acquiring data.

MultiQuant 2.1.1 on a 64 bit pc does not show reporting options

MultiQuant 2.1.1 will not show reporting options on a 64 Bit operating system unless 64 Bit Microsoft Office is installed

07/08/2016    MultiQuant Software

How Do I Prevent a Windows 10 Upgrade on my SCIEX Windows 7 Desktop

Microsoft has started to strongly encourage users to upgrade from the Windows 7 operating system to the Windows 10 operating system. This action might result in an unwanted or accidental upgrade. As of July 2016 none of the SCIEX software products have been fully tested on the Windows 10 platform. We cannot confirm therefore that the SCIEX software will perform as expected on the Windows 10 operating system.

07/05/2016   

How to check Operating System Locale on Windows 7

SCIEX software is (unless stated otherwise in release notes) only supported on systems with a Locale of en-US United States. The process to accurately check your system locale is described below.

06/02/2016    Software

Cliquid Error Retrieving the COM class factory for component with CLSID

Cliquid will run samples successfully but will be unable to process them and will report Error Retrieving the COM class factory for component with CLSID 36977493A67011Dc8Dcc00104BC5f89A at the bottom of the window.

06/02/2016    Cliquid Software

Multi-Page Printing Subsequent pages identical to the first.

A corruption in the local user profile can cause Analyst to print pages incorrectly with multipage documents having all pages as the first.

06/02/2016    Analyst Software

Application Event Log Error - Analyst Event ID - 2 - Category FMAN [CompDocDrvDLL][Error][File: CreateOpenCompDoc.cpp][Line 569]

This article describes the cause of this Event which can effect network acquisition

06/02/2016    Analyst Software

Can I display the pressure trace of a chromatogram when I use an Agilent LC system with Analyst

Description how to activate the pressure trace in the hardware profile

06/02/2016    Analyst Software

Unhandled exception has occurred Waters Acquity Method Editor v1.4 & 1.5

When saving or opening a method with the Waters Acquity Method Editor an unhandled exception occurs System.NullReferenceException Object reference not set to an instance of an object

06/02/2016    Analyst Software

How to wire SCIEX AUXIO cable for use with a Waters Acquity HPLC System

Diagram of how to wire AUXIO connections for the Acquity HPLC including the Stop Flow on instrument error

06/02/2016    Mass Spectrometers

Generating Excel Reports in Chemoview 2.0.2 Fails With Message Programmatic Access to Visual Basic Project is not trusted

When creating excel reports using Chemoview 2.0.2 the report creation will fail and the message Programmatic Access to Visual Basic Project is not trusted will be displayed in the report preview.

06/02/2016    Clinical | ChemoView Software

Tuning 4500,5500 and 6500 using Instrument Optimization

Walk through of instrument optimization

02/05/2016    Mass Spectrometers

Venting and Pumping Down the 5500 Series Mass Spectrometer

How to remove the vacuum and pump the machine back down afterwards

02/05/2016    Mass Spectrometers

Submitting and Starting Sample Batch in Analyst® Software

How to start acquiring data using Analyst software

Create Acquisition Method with Agilent HPLC in Analyst® Software

Walk Through of Analyst acquisition method (.dam) creation when a Agilent HPLC is employed.

Turbo V™ Ion Source Heater Replacement

How to replace the ion source heaters in the Turbo V Ion Source

02/05/2016    QTRAP Systems | Triple Quad Systems

TripleTOF® System Vacuum Interface Routine Cleaning

How to clean the vacuum interface of the TripleTOF instruments

Create Acquisition Method with Shimadzu HPLC in Analyst® Software

Walk through of creating an Analyst acquisition method (.dam) when a Shimadzu HPLC is employed.

SCIEX 5500&6500 Systems Pump Oil Change

How to change the oil in the pumps for the 5500 and 6500 series instruments

Setup of Diverter Valve

How to setup a diverter valve, including plumbing and Analyst software setup.

How do I debug MultiQuant Queries

Often when developing MultiQuant queries it can be useful to see the calculations which are performed during the query. By setting MultiQuant queries to debug mode you can view the files generated in excel allowing you to fix any errors in the calculations

12/22/2015    MultiQuant Software

How Do I Import and Export ChemoView Settings

ChemoView settings can be Exported so that they can be backed up or transferred between instruments or computers using the Import function.

12/22/2015    Clinical | ChemoView Software

How can I create a record of the security settings from Analyst Software

Explains how to record your security settings from an Analyst workstation in either printed format or PDF file using a PDF printer.

12/22/2015    Analyst Software

How Do I Migrate Data from a DiscoveryQuant™ 2.1 SQL Server to a DiscoveryQuant™ 3.0 SQL Server

This article describes how to migrate DiscoveryQuant 2.1.x SQL Server Data to a DiscoveryQuant 3.0 SQL Server Installation

12/22/2015    Pharma CRO | DiscoveryQuant Software

How Do I Install SQL Server 2014 for DiscoveryQuant™ 3.0

This article describes the process for building a SQL Server for use with DiscoveryQuant 3.0.

12/22/2015    Pharma CRO | DiscoveryQuant Software

How can I convert .wiff to NetCDF format

Explanation of how to convert .wiff files to NetCDF using the Translat.exe program which is included with Analyst software

10/02/2015    Analyst Software

DiscoveryQuant Cannot set spectrum for experiment X

DiscoveryQuant Optimize will not complete optimization with the error message Cannot set spectrum for experiment followed by a number which can be any one of your scan functions.

10/01/2015    Pharma CRO | DiscoveryQuant Software

How do I measure Peak Signal to Noise in Analyst Software

This article describes how to measure signal to noise using Explore or Quantitate mode with Analyst Software.

10/01/2015    Analyst Software

DiscoveryQuant Quicktune DP 0 DP Scan Problem

Using DiscoveryQuant 2.1.3 Quick Tune will set the DP value to 0 and then Fine Tune will fail as it has an invalid DP value. The temporary Q3 MI scan method for the quicktune will show the MH ion with 2 DP scans both at 200v though this voltage may vary.

10/01/2015    Pharma CRO | DiscoveryQuant Software

MarkerView Microsoft Office 2013 This method or property is not available because this command is not available for reading.

When Markerview 1.2.1 is used in conjunction with Microsoft Office 2013 report generation fails with the message This method or property is not available because this command is not available for reading.

10/01/2015    Academia Omics | MarkerView Software

The Analyst application cannot be started because the current user is not in the security database.

When Analyst is started the message The Analyst application cannot be started because the current user is not in the security database or has not been assigned a user type. You may also get this message if the network is not available. Please contact your administrator.

10/01/2015    Analyst Software

Crashing on Windows 7 when in ExploreQuantitate Mode AB Sciex Analyst has stopped working

When using Analyst versions 1.6.x with Windows 7 Operating System Analyst will stop with the message AB Sciex Analyst has stopped working. This will usually happen when the mouse cursor is moved across the chromatogram pane.

10/01/2015    Analyst Software

Reporter 3.0.1 Templates The file contains custom XML elements which are no longer supported by Word.

When opening a reporter 3.0.1 XML Template in Microsoft Word 2007 SP1 then the error message The file contains custom XML elements which are no longer supported by Word. If you save this file these custom XML elements will be removed permanently

10/01/2015    Analyst Software

How Do I Change the Significant Figures of Regression Equation in Analyst

Description of how to change the display of the regression equation in Analyst

10/01/2015    Analyst Software

Multiquant 3.0.x Installation Fails. No .NET Framework 3.5 SP1 on Windows 7

Multiquant 3.0.x installation is not able to proceed on Windows 7 Operating system because the installation of .NET framework is not completed despite the inclusion of this framework within the Windows 7 Operating System.

10/01/2015    MultiQuant Software

Analyst.exe Unable To Locate Component pt95FKn71.dll

When Launching Analyst or Activating a Hardware Profile you receive the message Analyst.exe Unable To Locate Component with message body This application has failed to start because pt95Fkn71.dll was not found. Reinstalling the application may fix this problem.

10/01/2015    Analyst Software

LibraryView 1.0 Error 21467259 failed to create SQL database Unknown Error

When installing LibraryView 1.0 the following error message is shown. Error 21467259 failed to create SQL database LibraryView error detail Unknown Error.

Unspecified error when using Quantitate in Analyst Software

This article describes how to resolve the Unspecified error message encountered when trying to quantitate a new batch with Analyst Software

10/01/2015    Analyst Software

Cliquid 3.2 or MultiQuant 2.1 Installation Failure Component Visual C 2010 Runtime Librariesx86 has failed to install.

Cliquid 3.2 or MultiQuant 2.1 Installation Failure Component Visual C 2010 Runtime Librariesx86 has failed to install with the following error message Asia. Visual C 2010 Runtime Libraries x86 failed to install.

MultiQuantで、Quantitation MethodまたはResults Tableを作成する時に選択した代表サンプルを変更して、各MRMトランジションのExpected Retention Timeや積分パラメーターを設定するにはどうすればよいですか?

この記事は、MultiQuantソフトウェアで、Quantitation MethodまたはResult Tableを作成する時に選択した代表サンプルを変更する方法について記載しています。

08/04/2022   

怎样在MultiQuant定量方法或结果表中改变参考样品,改变MRM通道设置保留时间和积分参数

这文章给出改变MultiQuant软件改变参考样品的指引

08/04/2022   

Sciex OS WIFF2ファイルのMzMLおよびMzXML形式への変換

MzMLおよびMzXML形式に変換するためのProteowizardツール (http://proteowizard.sourceforge.net/downloads.shtml)で、SCIEXOS 1.2および1.3で作成されたWIFF2ファイルが動作します。

05/17/2022   

十個建議減少LC/MS系統汙染

日期:05/21/2021 僅提供研究使用

06/28/2021   

Analyst®ソフトウェアで、Projectフォルダーのソート順を変更することはできますか?

Analyst®ソフトウェアには、内部ソートの機能がありません。プロジェクトをソートするには、FindFirstFileおよびFindNextFileというAPI関数を使って、ディレクトリーからファイルを読み取ります。ファイル名を返す順序は、File systemの種類(NTFS、CDFS、またはFAT)によって異なります。この記事には、そのことが記載されています。

10/30/2020   

SCIEX OSソフトウェアを使用する場合のCドライブの空き容量要件は?

SCIEX OSソフトウェアは、Cドライブに利用可能な空き容量が20 GBある場合に、最高のパフォーマンスを発揮します。更に、SCIEXOSソフトウェアは、装置(測定PC上)とソフトウェア(測定PCと解析PCの両方)の両方のパフォーマンスをモニターするためにログファイルを作成します。これらのログは、合計サイズが35 GBになることもあります。 そのため、SCIEX OSソフトウェアを快適に使用するのに、Cドライブに必要な55 GBのスペース制限が設定されています。この記事には、そのことが記載されています。

05/14/2020   

如何成为仪器的线上“所有人”

成为仪器的线上“所有人”后能够通过SCIEXNow Online实现实验室仪器的线上管理。操作方法为,在登录状态下进入https://sciex.com.cn/support 。在出现的页面中点击SCIEXNow 仪表板中的“仪器”模块...

03/30/2020   

成为仪器“所有人”后能获得哪些权限?

注册和登录sciex.com.cn 用户名后,该仪器直接显示在账号中;能访问该仪器的所有支持案例(无论是哪位使用人创建的案例); 能够为该仪器在线提交新的支持请求;可以为该仪器命名或修改命名昵称;能够访问与该仪器相关的所有状态信息*;能够控制SCIEXNow Online用户列表,及仪器使用者对该仪器的访问权限...

03/30/2020   

LightSight® ソフトウェアのAcquisitionモードは、 SCIEX 6500+ LC-MS/MS システムではサポートされていません。

Description:LightSight software version 2.3.x acquisition mode is not supported on a SCIEX QTRAP or Triple Quad™ 6500+ LC-MS/MS System. LightSight®ソフトウェアバージョン2.3.x のAcquisitionモードは、SCIEX QTRAP®またはTriple Quad™6500+ LC-MS / MSシステムではサポートされていません。この記事には、そのことが記載されています。

11/09/2019   

MultiQuant™ ソフトウェアのレポーターエラー: Object Reference Not Set to an Instance of an Object

MultiQuant™ ソフトウェアでレポートを作成しようとすると、エラー:「Object reference not set to an instance of an object」が表示される場合は、「Create Report」ダイアログボックスでレポートテンプレート以外のファイルが選択されている可能性があります。タグ付きのテンプレートファイルが選択されているかどうかを確認してください。この記事には、そのことが記載されています。

10/29/2019   

レポートテンプレートにQueryファイルを更新またはリンクする方法

Query(クエリー)の名前を変更または更新した場合や、新しいQueryをレポートテンプレートに添付したい場合は、MultiQuant™、Analyst®、またはSCIEX OSソフトウェアで作成するレポートに使うテンプレートにQueryを再リンクする必要があります。この記事には、そのことが記載されています。

10/23/2019   

SCIEX OSソフトウェアで使用できる積分アルゴリズムは何ですか?

この記事には、SCIEX OSソフトウェアで使用できる積分アルゴリズムの種類が記載されています。SCIEX OSソフトウェアには、3つの積分アルゴリズムがあります。Analyticsモジュールの 「Projects」→「Project Default Settings」 にリストされている「MQ4」 、 「AutoPeak」 、 「Summation」です。

10/22/2019   

LIMSテンプレートのフォーマットについて

MultiQuant™ソフトウェアのResults TableからLIMSシステムにデータを転送するのに、LIMSテンプレートを使用します。 LIMSテンプレートは、レポートの上部に出力するフィールドがリストされたカンマ区切りのファイルです。テンプレートの各フィールドは、カンマで区切る必要があります。この記事には、そのことが記載されています。

10/22/2019   

SCIEX OS 1.6 .1ソフトウェアで積分アルゴリズムを変更する方法

SCIEX OSソフトウェアのAnalyticsモジュールで、定量解析用Processing Methodの積分パラメータを変更するには、ProjectsメニューからProjects default settingsを選択し、Quantitative Processing→Integration Defaults→Integration Algorithmから変更してください。この記事には、そのことが記載されています。

10/17/2019   

Analyst®または MultiQuant™ソフトウェアのResults Tableで、StandardサンプルのActual Concentration値が入力されていない場合、検量線が表示されません。

この記事には、MultiQuant™またはAnalyst® ソフトウェアのResults Tableで、Standardサンプル(検量線の標準溶液サンプル)のActual Concentration値(実際の調製濃度値)を入力しないと、検量線が表示されないことが記載されています。

10/17/2019   

Analyst® Device Driverをアンインストールせずに、 Analyst®ソフトウェアを再インストールすると、Acquisition Methodが正しく動作しません。

Analystソフトウェアと一緒にAnalyst® Device Driver (ADD)をインストールする場合は、プログラムのインストール順序が重要です。最初にAnalystソフトウェアをインストールし、次にADDをインストールする必要があります。この記事には、そのことが記載されています。

10/04/2019   

Analyst® ソフトウェアの化合物ライブラリーをSciex OS ソフトウェアへ移行する方法

この記事には、Analystソフトウェアの化合物ライブラリーをSciex OSソフトウェアに移行する手順が記載されています。Sciex OSソフトウェアのLibraryモジュールからインポートオプションで、Analystの化合物ライブラリー(.mdbファイル)を選択します。 インポートしたライブラリーに名前を付けます。

10/03/2019   

Analyst®ソフトウェアをアップグレードした後、データファイルにxx.wiff.scanファイルが含まれているのはなぜですか?

この記事には、Analyst®ソフトウェアをアップグレード後、データファイルにアップグレード前にはなかったxx.wiff.scanファイルが含まれていた場合、取得するデータファイル形式を以前の設定に変更する方法が記載されています。Configureモードを選択し、「Tools」、「Settings」、「Queue Options」の順にクリックして、Queue Options画面を開き、「Use flat files for scan data」のチェックボックスをオフにしてください。

10/01/2019   

SCIEX OSソフトウェアエラー: 「Cannot Open LibraryViewServiceHost Service on Computer 」の解決方法

Administrator権限のないユーザーがWindowsにログインし、SCIEX OSソフトウェアでAnalyticsモードにアクセスしようとすると、 「Error has occurred:Cannot open LibraryViewServiceHost service on computer.」というエラーが表示されることがあります。Analyticsモードを開いた時に、LibraryViewServiceHostが開始されなかったためです。LibraryViewサービスを実行する必要があります。この記事に記載されている回避策のいずれかをお試しください。

09/27/2019   

Water’s Driver Packをインストールする際の、Analyst® ソフトウェアのセキュリティーモードに関する推奨事項

この記事には、Waters' Driver Pack 4 (DP4) またはDriver Pack 4 supplemental release (DP4 SR1)と一緒にAnalyst® ソフトウェアをインストールする場合の、Analystセキュリティーモードの選択に関して記載されています。

09/27/2019   

SCIEX 5500/6500+シリーズのMSとWaters Acquity LC とのIPアドレスの競合を防止する方法

SCIEX 5500/6500+シリーズのMS装置を使用する場合は、IPアドレスの競合を避けるためにWatersのIPアドレスを変更してください。Waters LCコンポーネントのIPアドレスを変更するには、C:\\Program Files\Waters Instruments\Waters DHCP ServerConfiguration.exeファイルを使用します。この記事には、そのことが記載されています。

09/26/2019   

SCIEX OS ソフトウェアで、定量トランジション(Quantifiers)のみのレポートを作成する方法

この記事には、SCIEX OSソフトウェアでResults Tableの定量トランジション(Quantifiers)だけをレポートに出力する方法が記載されています。AnalyticsワークスペースからResults Tableを開きます。 「More」→「Table Display Settings」をクリックすると、列(カラム)名のリストが表示されます。「Reportable」を選択してください。結果をレポート、エクスポート、LIMS転送に含めるかどうかを「Reportable」列から選択できます。「Reportable」列で、「Quantifiers」のトランジションを選択してください。

09/23/2019   

SCIEXのソフトウェアで取得、解析したデータの転送や保存に、Google Driveを使用できますか?

データストレージとしてGoogle Driveを利用することは、SCIEXのソフトウェアで取得、解析したデータセットでは検証されていません。Google Driveを使用したデータの転送と保存は、暗号化プロセスがGoogle Driveに組み込まれている可能性があるため、一部のエンドユーザー様のデータセットで問題が発生しています。この記事には、そのことが記載されています。

09/10/2019   

SCIEX OS 1.6.1 ソフトウェアで作成したサービスパッケージ(Service Package) はどこに保存されますか?

この記事には、SCIEX OS 1.6.1ソフトウェアで作成したサービスパッケージ(Service Package)の保存先が記載されています。すべて、C:\ ServicesPackagesフォルダーにzip(圧縮)ファイルで保存されます。

08/09/2019   

BPV Flex 1.0ソフトウェアで「カスタム酵素」を作成する方法

この記事には、BPV Flex 1.0ソフトウェアでカスタムな制限酵素を使用したい場合のやり方が記載されています。「BPV Flex DataDictionary.xml」ファイルの「Digestion Agents 」セクションに、目的の酵素の定義を入力するか、コピー&ペーストしてください。

08/09/2019   

Sciex OS ソフトウェアのAnalyticsワークスペースに、新しいFlagging Ruleを追加する方法

この記事には、SCIEX OS ソフトウェアのAnalyticsワークスペースに、新しいFlagging Rule を追加する手順が記載されています。Analyticsワークスペースを開き、 「Process Method」をクリックし、 「New」を選択します。「 Flagging Rules」ページを選択し、「Add Rule」をクリックします。

08/09/2019   

Windows10でLipidView™ 1.2ソフトウェアを起動すると、ライセンスエラーが発生する場合

Windows10でLipidView™ 1.2ソフトウェアを起動すると、永続ライセンスがインストールされている場合でも、ライセンスの期限が切れていることを示すライセンスエラーが表示されることがあります。この記事には、この問題の解決策が記載されています。LipidViewソフトウェアアイコンを右クリックし、 「Run as Administrator」を選択してソフトウェアを起動してください。

08/09/2019   

BioPharmaView™ソフトウェアにおけるインタクトプロテインのTheoretical Average Massの計算

BioPharmaView™ソフトウェアでは、NISTがオンラインで公開している同位体質量を使用しています。https://physics.nist.gov/cgi-bin/Compositions/stand_alone.pl この記事には、そのことが記載されています。

08/09/2019   

Accurate Mass Metabolite Spectral Library 1.0のインストール

この記事には、Accurate Mass Metabolite Spectral Library 1.0のインストール手順が記載されています。化合物データベースをインストールするための有効なライセンスファイルが必要です。ライブラリーをインストールすると、Start→All Programs→AB SCIEX→Accurate Mass Metabolite Spectral LibraryフォルダーにAccurate Mass Metabolite Spectral Library用のフォルダーが作成され、ライブラリーとユーザードキュメントがこの場所にコピーされます。

08/09/2019   

SCIEX OS 1.5ソフトウェアで、Ion Ratioのフラグを立てるルール設定の方法

SCIEX OSソフトウェアでIon Ratioの フラグを立てるルールを設定するには、Process Methodを選択し、Editを選択します。このメニューの「Flagging Rules」の「Ion Ratio Acceptance」オプションで、ルールを変更することができます。この記事には、そのことが記載されています。

08/08/2019   

次のSCIEXOSエラーを解決するための手順: SciexLibraryService Rejected the Session-Establishment Request

次のSciex OSエラーを解決するには、この記事に記載された手順に従いポート8081を変更してください。エラー:SciexLibraryService Rejected the Session-Establishment Request.

07/24/2019   

出荷時、iTRAQ®試薬に使用される有機溶媒は何ですか?

すべてのiTRAQ®、aTRAQTMおよびmTRAQ®試薬は、アセトニトリル溶液で工場から出荷されます。この記事には、そのことが記載されています。

07/24/2019   

PeakView®ソフトウェア内のCloudConnectとSWATH®MicroAppsはWindows10と互換性がありますか?

OneOmicsワークフローおよび/またはSWATHタンパク質データ解析を実施したい場合は、ソフトウェアパッケージ、「PeakView®2.2にCloudConnect 1.2ベータ版とSWATH®2.0 .1ソフトウェアをインストール」が必要です。このソフトウェアパッケージは、Windows 7およびWindows 10,64-bitと互換性があります。この記事には、そのことが記載されています。

07/14/2019   

ProteinPilot™ ソフトウェア 5.0.2は、 MALDI TOF/TOF™ システムをサポートしていますか?

この記事には、どのProteinPilot™ソフトウェアバージョンが4800および5800MALDI TOF/TOFTMシステムをサポートしているかが記載されています。

07/14/2019   

MultiQuant™ソフトウェアのQuantitation MethodをSciex OSソフトウェアのProcessing Methodへ変換する方法

この記事は、MultiQuant™3.0.3ソフトウェアのQuantitation Methodファイル(.qmethod)をSciex OS 1.5ソフトウェアのProcessing Methodファイル(.qmethod)に変換するためのステップバイステップガイドです。

06/26/2019   

Skylineバージョン4.2.1以降は、.wiff2ファイル形式を解析できますか?

Skylineバージョン4.2.1以降では、SCIEX OSソフトウェアで取得した.wiff2ファイルを解析することができます。この記事には、そのことが記載されています。

06/14/2019   

SCIEX OSおよびLibraryView™ソフトウェアの一般的なSQLインストールエラー

SQLベースのソフトウェアコンポーネントを含むプログラム(例:SCIEX OSおよびLibraryView™ソフトウェア)をインストールする場合は、一定のルールがあります。Microsoftによってこれらのルールが設定されています。この記事には、SQLコンポーネントを含むSCIEXソフトウェアがインストールできなかった例とその解決策が記載されています。

05/23/2019   

MultiQuant®ソフトウェア 3.0.3バージョンにアップグレードした後、 「Access is Denied 」エラーが表示される場合

Windows 10においてMultiQuantソフトウェア3.0.2を3.0.3にアップグレードした後、最初はソフトウェアが起動したのに、その後ソフトウェアを立ち上げると「Access is denied」というエラーが表示される場合、MultiQuantソフトウェアの再インストールをしてください。この記事には、そのことが記載されています。

05/23/2019   

Analyst® ソフトウェアでShimadzu LCを含むProfileがActivateできない場合の解決事例

この記事には、Shimadzu LCを含むHardware Profile(ハードウェアプロファイル)がエラーでActivateできない事例が記載されています。Shimadzuシステムコントローラー(CBM)の「Configuration」タブで、Serial PortフィールドをTCP/IPに変更し、IPアドレス192.168.200.99を追加したら、Activateできました。

05/17/2019   

Analyst®ソフトウェアのエラーメッセージ:Failed To Set Sample Data

この記事には、Analyst®ソフトウェアを使用している時に、「Failed to set sample data(サンプルデータの設定に失敗しました)」というエラーメッセージが表示された場合の解決策が記載されています。

05/17/2019   

DiscoveryQuant™ 3.0.1ソフトウェアのAnalyzeモードで化合物パラメータがロードできない

この記事には、LocalデータベースからSQLデータベースに切り替えた後、Reviewデータベースとして選択したデータベースに問題があり、DiscoveryQuant™ 3.0.1ソフトウェアのAnalyzeモードで化合物パラメータをアップロードできなかった事例とその解決策が記載されています。

05/14/2019   

SCIEX OS Dataフォルダーがいっぱいになると、SCIEX OSソフトウェアによるデータ取得を停止する様なシステムエラーが発生する場合があります。

「SCIEX OS Data」フォルダーが保存されているドライブがいっぱいになると、Sciex OS 1.5ソフトウェアによるサンプルのデータ取得を停止する様なシステムエラーが発生する場合があります。古いデータをバックアップして削除すると、データ取得が再開できる可能性があります。この記事には、そのことが記載されています。

05/13/2019   

CE-SDSアプリケーション用のSCIEXプレアッセンブルドキャピラリーカートリッジの仕様

この記事は、SCIEXプレアッセンブルドキャピラリーカートリッジ(製品番号A55625)の仕様について説明しています。

05/03/2019   

レーザ誘導蛍光(LIF)のキャリブレーション補正係数(CCF)

レーザ誘導蛍光(LIF)のキャリブレーション補正係数(CCF)とは、既知濃度の分析対象物からの蛍光と機器で検出した関連シグナルとの数学的な関係を表します。この記事には、CCFの計算方法が記載されています。

04/23/2019   

SCIEX OSソフトウェアで、ライブラリー検索結果との一致度合いをPurity Scoreを使って評価する

SCIEX OSソフトウェアは、未知のスペクトルとライブラリースペクトルの両方のピークからPurity Scoreを計算します。化合物が既存のライブラリー化合物とどれだけ一致するかを評価するために、Purity Scoreを使用します。値が高いほど、未知のスペクトルが正しく同定されている可能性が高いことを示し、値が低いほど、一致が不確実であることを示します。この記事には、そのことが記載されています。

04/23/2019   

SCIEX OS ソフトウェアで、レポートに表示するロゴを変更する方法

この記事には、SCIEXOSソフトウェアでResults Tableを確認後、レポートに表示するロゴを置き換える方法が記載されています。 「Reporting」 、「Create Report, and then save the Results Table」の順にクリックし、「Replace Logo」をクリックしてください。

04/19/2019   

SCIEXライブラリーで検索時、Precursor Mass Toleranceが0.01 Daに設定すると、ヒットしないのはなぜですか?

SCIEXライブラリーで検索時、Precursor Mass Toleranceを0.01 Daに設定すると、ヒットしない場合があります。これは、SCIEXライブラリーの一部に、不正確なPrecursor(例:小数点以下一桁のみ)のm/zで取得されたスペクトルが含まれているためです。この記事には、そのことが記載されています。

04/19/2019   

SCIEX OSソフトウェアのNon-targeted Peaks検索のアルゴリズムで変更できるパラメーター

SCIEX OSソフトウェアのAnalyticsモードでは、Non-targeted Peak検索のアルゴリズムにより、どのピークをライブラリー検索またはFormula Finder検索に含めるかを決定します。ここでは、変更可能なパラメーターについて記載しています。

04/17/2019   

SCIEX OS ソフトウェアにCFR ライセンスをインストールする方法

この記事には、SCIEX OSソフトウェアにCFRライセンスをインストールする仕方が記載されています。CFRライセンスファイルをSCIEXOSライセンスが保存されているC:\ Program Files\Sciex\Sciex OSフォルダーへ保存してください。

04/15/2019   

32Karatのメソッドからレポートやデータグラフィックをエクスポートする方法

この記事には、32 Karatのメソッドからレポート(例:%エリアレポートなど)やデータグラフィック(注釈付きのエレクトロフェログラム)をエクスポートする手順が記載されています。

04/05/2019   

SCIEX OSソフトウェアでUser Role(ユーザーロール)が正しく割り当てられていない場合

SCIEX OSソフトウェアにエラー、「You do not have the correct SCIEX OS role permissions to access this product (この製品にアクセスするための正しいSCIEX OSのRole権限がありません)」が表示される場合、ソフトウェアをインストールしたWindowsユーザーでソフトウェアにログインしてください。この記事には、そのことが記載されています。

04/05/2019   

CEQ/GeXPゲルカートリッジの気泡を除去する方法

この記事には、ゲルラインに入る可能性のあるゲルカートリッジ内の気泡を取り除くための遠心プロトコールが記載されています。

04/04/2019   

32 Karat ソフトウェアのライセンスキープログラムとユーザーライセンスの種類について

32Karatソフトウェアを起動するにはハードウェアライセンスキーが必要です。古いバージョンでは同様のソフトウェアライセンスキーをフロッピーディスクからインストールします。「Key.exe」プログラムを使用するとライセンスの内容を表示することができます。この記事には、そのことが記載されています。

04/02/2019   

CEQ/GeXPデータをABI形式でエクスポートする方法

この記事は、CEQ/GeXPソフトウェアで取得したデータファイルをデータの再解析のために、ABI形式でエクスポートする方法について記載しています。

04/02/2019   

Sciex OS ソフトウェアのFormula Finder アルゴリズムはどのように機能しますか?

SCIEX OSソフトウェアのFormula Finderアルゴリズムは、プリカーサーイオンの質量精度、同位体パターン、およびMS / MSフラグメンテーションパターンを使って、MSとMS / MSスペクトルに基づいて、可能な組成式を予測しようとします。この記事には、そのことが記載されています。

04/02/2019   

32 Karat ソフトウェアのユーザー権限の概要Shape

この記事には、32 Karatソフトウェアの各ユーザー権限の概要(ユーザーに割り当てたり、ユーザーから削除したりできる権限)に関する情報が記載されています。

04/02/2019   

SCIEX OSソフトウェアでのTOF MSまたはTOF MS / MSスペクトルの再キャリブレーション

SCIEX OSソフトウェアで、TOF MSまたはTOF MS / MSスペクトルの再キャリブレーションまたはサンプルの再キャリブレーションをするには、Exploreモードからデータファイルを開き、「Process」を選択してから、「Recalibrate Spectrum」または「Recalibrate Sample」を選択してください。この記事には、そのことが記載されています。

03/21/2019   

SCIEX OS 1.x ソフトウェアのアンインストールと再インストール

この記事は、SCIEX OSソフトウェアをアンインストールする方法と、特定のファイルを手動で削除し、ソフトウェアを完全に削除する方法について記載しています。

03/21/2019   

SCIEX OSソフトウェアからセントロイドスペクトルを出力する方法

この記事には、SCIEX OSソフトウェアからセントロイドスペクトルを出力する手順が記載されています。Exploreモードでスペクトルデータを開き、「Process」→「Centroid Spectrum 」をクリックし、「File」→「Export」で出力することができます。

03/01/2019   

SCIEX OS ソフトウェアで「Sum Multiple Ions」オプションがグレーアウトしている理由

この記事には、SCIEX OSソフトウェアのQuantitation Methodで「Sum Multiple Ions」オプションがグレーアウトしている場合の確認項目について説明しています。各化合物のグループ名を「Group」カラムに入力する必要があります。

02/28/2019   

Analyst® ソフトウェアの検量線およびメトリックプロットに表示される桁数を変更する方法

この記事には、AnalystソフトウェアのQuantitationモードで表示する検量線やメトリックプロットの桁数を変更する方法が記載されています。デフォルトの桁数では、Results Tableに示されている結果を再現することができません。レジストリを変更する必要があります。レジストリの変更は危険なため、お客様に知らせるための警告が表示されます。

02/28/2019   

PeakView® ソフトウェアには、いくつの修飾アミノ酸や修飾を追加することができますか?

PeakViewソフトウェアでは、追加できる修飾アミノ酸と修飾の数に制限はありません。 この記事には、そのことが記載されています。

02/28/2019   

Reporter 3.2: Custom Column(カスタム列)をレポートテンプレートに追加する方法

Custom Column(カスタム列)をレポートテンプレートに追加し、Custom Columnのデータ値をAnalyst Reporter 3.2で作成するレポートに出力することができます(Analystソフトウェア経由)。この記事には、その方法が記載されています。

02/28/2019   

Analyst®ソフトウェアのパラメーター設定のオプション変更

Analyst®ソフトウェアの個々のパラメーター設定(Parameter Settings)のオプションを変更するには、「Configure」または「Tune and Calibrate」モードを選択し、Tools > Settings > Parameter Settingsへ進んでください。この記事には、そのことが記載されています。

02/28/2019   

SCIEX OS 1.5 ソフトウェアの起動エラーを解決するには、Clearcore2 ServiceをStart(開始)してください。

SCIEX OS 1.5ソフトウェアの場合、Clearcore2 Serviceがバックグラウンドで動作しています。SCIEX OSが起動しない場合は、コントロールパネルの 「Services」セクションからClearcore2 Serviceを手動でStart(開始)してください。この記事には、そのことが記載されています。

02/28/2019   

Analyst®ソフトウェアで最後のサンプルのデータ取得後、特定のコンディションでLCMSシステムを稼働する方法

この記事には、Analyst®ソフトウェアで最後のサンプル測定が終了後、設定したコンディションでシステムを稼働させ続ける方法が記載されています。

02/28/2019   

SCIEX OS でAutoPeak積分アルゴリズムを使用する場合の「Saturation correction(サチュレーション補正)」の設定

この記事は、SCIEXOSソフトウェアでAutoPeak積分アルゴリズムを使用した際の「Saturation correction(サチュレーション補正)」の設定について記載しています。 「Saturation correction」機能を使用すると、検出器のサチュレーション効果を補正できます。Quantitation Methodの「Saturation correction」ボタンを選択し、しきい値を指定します。

02/15/2019   

SCIEX OS ソフトウェアによるライブラリー検索には、どんなアルゴリズムがありますか?

この記事では、SCIEX OSソフトウェアのAnalyticsモードで構築する解析メソッドで選択できる3つのライブラリー検索用アルゴリズムについて説明されています。Candidate Search, Confirmation Search、Smart Confirmation Searchです。

02/15/2019   

SCIEX OSの「AutoPeak」積分アルゴリズムでグループ内のすべての化合物に同じピークモデルを使用する設定

この記事には、SCIEX OSの「AutoPeak」積分アルゴリズムでグループ内のすべての化合物に同じピークモデルを使用するための設定方法が記載されています。解析メソッドを作成する前に「Project Default Settings」の「Peak Selection by 」を「Group」にし、「Process by Group」にチェックを入れてください。

02/15/2019   

SCIEX OSでAutoPeak積分アルゴリズムを使う時の「Peak Selection」の選択

この記事では、SCIEX OS でAutoPeak積分アルゴリズムを使う時に、どのような種類の「Peak Selection」を選択できるかについて説明しています。

02/15/2019   

SCIEX OSソフトウェアで別のResults TableのColumn Settingsを適用させる方法

この記事では、Sciex OSソフトウェアのあるResult TableのColumn Settingsを別のResult Tableに適用させる方法が記載されています。AnalyticsモードでResult Tableを開きます。 次に、「More」ボタンをクリックし、「Table Display Settings」を選択して表示される画面で、Result Tableに表示したいカラムを設定し、.csetファイル形式でエクスポートします。別のResult Tableでこのファイルをインポートします。

02/15/2019   

SCIEX OS 1.x や PeakView ソフトウェアでBio Tool Kitを使用するには、別途Bio Tool Kitソフトウェアライセンスが必要です。

Bio Tool KitはPeakView 2.xおよびSCIEX OS 1.xソフトウェア内で利用できますが、別途Bio Tool Kitソフトウェアライセンスが必要です。この記事には、PeakView 2.xやSCIEX OS 1.xソフトウェアでBio Tool Kitソフトウェアライセンスをインストールする方法が記載されています。

02/08/2019   

BioPharmaView™ソフトウェア2.x / 3.0.xでは、最初のサンプルのデータが破損している場合、後続のサンプルのデータを開くことができません。

この記事には、BioPharmaView™ソフトウェア2.x / 3.0.xでは、最初のサンプルのデータが破損している場合、後続のサンプルのデータを開くことができないことが記載されています。

02/08/2019   

SCIEX OS 1.5をWindows 7にインストールするにはTDC4ドライバーのアップデートが必要です。

SCIEX OS 1.5をWindows 7にインストールするには、TDC4ドライバーのアップデートが必要です。この記事には、TDC4ドライバーのアップデート方法が記載されています。Sciex OSのインストールフォルダー、「Drivers」フォルダー内に「xTDC4_driver_v1.1.0.exe」プログラムがあるはずです。これは、バージョン1.0.3を削除し、1.1.0をインストールするプログラムです。

02/08/2019   

SCIEXソフトウェアライセンスを別のコンピュータに移管する方法

この記事は、既にアクティベーションされたSCIEXソフトウェアライセンスを別のPCへ移管する為の手順について説明しています。

01/28/2019   

怎样转移SCIEX的软件至其他电脑上

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

01/28/2019   

MultiQuant™ソフトウェアでCSV形式のレポートを作成する方法

この記事は、MultiQuant™ソフトウェアで.csv形式のレポートを作成する手順を説明しています。Result Tableを開き、[File]メニューの[Create Report]を選択します。 コンマ区切りのレポートテンプレートを選択し、出力形式としてCSVを選択します。

01/24/2019   

SCIEXライセンスキーを有効にする方法

この記事は、SCIEXソフトウェアのライセンスキーを有効にする方法を説明しています。ユーザ名とパスワードを使用してwww.sciex.jpにログインします。https://sciex.jp/support/activate-softwareに移動し、必要なフィールドに入力します。

01/24/2019   

移動相にイオンペア試薬を使用する際に考慮する点は何ですか?

この記事には、イオンペア試薬と質量分析装置を使用する際の成功のヒントが含まれています。イオンペア試薬は問題のあるクロマトグラフィーに大きく役立ちますが、添加されたイオンペア試薬はLC部品やカラム、MSソースに付着する傾向があり、シグナル抑制やカラム性能の低下につながります。 

01/24/2019   

MultiQuant™软件如何生成.CSV格式的报告?

在MultiQuant™软件打开一个结果表,File菜单栏下选择Create Report,可生成.csv格式的报告。

01/24/2019   

iTRAQ® キットに付属のSix-Protein MixtureのSpecificationには何が記載されていますか?

iTRAQ®キットに付属のSix-Protein Mixture(PN 4348363)のSpecificationシートには、タンパク質のアクセッション番号およびチューブあたりの量(µgやnmol)の情報が含まれています。この記事には、そのことが記載されています。

01/09/2019   

標準のMutliQuant™ソフトウェアで作成したファイルとMultiQuant MDソフトウェアの互換性

この記事は、標準のMutliQuant™ソフトウェア(GLPバージョンまたは非GLPバージョン)で作成したファイルとMultiQuant MDソフトウェアとの互換性について説明しています。

12/28/2018   

レポーターテンプレート内のピークレビュークロマトグラムの向きの変更

この記事は、Analyst®またはMultiQuant™ソフトウェアのレポート出力で、ピークレビュークロマトグラムが間違った向きで表示される場合の解決策について記載しています。実際のWordテンプレートのページの向きが横向きに設定されているか確認してください。

12/28/2018   

MetabolitePilot™ソフトウェアの化合物のライブラリー結果のフィルタリング

MetabolitePilot™ソフトウェアのResult画面の右上にある青いファネルアイコンを利用すると、「Potential Metabolite」の可能性がある化合物を探すのに解析したInformation-Dependent Acquisition (IDA) データの検索結果を更に絞り込むことができます。この記事には、そのことが記載されています。

12/28/2018   

MultiQuant™ ソフトウェアのResults Tableの「Sample Name」と「Sample ID」カラムに入力できない文字(記号)

この記事には、MultiQuant™ ソフトウェアのResult Tableの「Sample Name」と「Sample ID」カラムに、次の文字が使用できないことが説明されています。使用できない文字は、 : \ / : * ? " < > | =. です。

12/28/2018   

Analyst®1.7ソフトウェアによるExion LCシステムのリアルタイムでの圧力確認

Exion LCシステムの圧力変動をリアルタイムにレポートすることは、Analyst®ソフトウェアではできません。これまでのところ、この機能はAnalyst Device Driverを使用して制御するAgilent LCシステムでのみ可能です。この記事には、そのことが記載されています。

12/28/2018   

MetabolitePilot™ 1.5 ソフトウェアアップグレードライセンスには、古い1.0のライセンスがベースとして必要です。

この記事には、MetabolitePilot™1.5ソフトウェアをインストール後起動すると、デモバージョンのソフトウェアライセンスの有効期限が切れていることを示すエラーが表示された場合の解決策が記載されています。インストールするライセンスがMetabolitePilot 1.5アップグレードライセンスである場合、元のMetabolitePilot1.0のライセンスと一緒にインストールする必要があります。

12/28/2018   

Tempフォルダーに取得したAnalystソフトウェアのデータファイルは、拡張子を変更してください

この記事には、AnalystソフトウェアのデータファイルをTempフォルダーまたはCacheフォルダーに取得した場合、データファイルの拡張子が.wiffまたは.wiff.scanではない可能性があり、ファイルを新しい場所に移動しようとする時は、データファイルの拡張子を.wiffまたはwiff.scanに変更する必要があることについて記載されています。

12/27/2018   

Analyst® ソフトウェアでSub-projectを設定したプロジェクトでは、「Tools」、「Settings」、「New Quantitation Results Table」から新規Settingsを作成することができません。

AnalystソフトウェアでSub-projectを設定したプロジェクトでは、Quantitateモードの「Tools」、「Settings」「New Quantitation Results Table」から新規にカスタムのTable Settingsを作成することができません。この記事には、そのことが記載されています。

12/27/2018   

ルートディレクトリ(Root Directory)を「Analyst Data」フォルダーに設定し直すとSelexion®DMSの機能が元に戻ります。

この記事には、Selexion Differential Mobility Spectrometer(DMS)を使用する場合のAnalyst®ソフトウェアのルートディレクトリ(Root Directory)設定について記載されています。ルートディレクトリを「Analyst Data」フォルダーに設定し直すと、DMS機能が元に戻り、AnalystソフトウェアのHardware Profileをアクティブにすることができます。

12/27/2018   

Analyst®TFソフトウェアにおけるITCパラメーターへのアクセス方法

AnalystTF ソフトウェアでイオントランスミッションコントロール(ITC)パラメータを変更すると、TripleTOFシステムのQJetイオンガイドをクリーニングする必要があるかどうかを判断するヒントになります。この記事は、AnalystソフトウェアでITCパラメータにアクセスする方法について説明しています。

12/27/2018   

MasterView™またはSCIEX OSソフトウェアでNIST ライブラリーを使用する場合のライブラリー検索の推奨設定

この記事には、MasterView™またはSCIEX OSソフトウェアでNISTライブラリーを使用する場合のライブラリー検索の推奨設定がリストされています。

12/27/2018   

Analyst® ソフトウェアで使われる積分タイプ(Integration Type)とは何ですか?

この記事には、Analystソフトウェアで使用される積分タイプ(Integration Type)の説明が記載されています。Analystソフトウェアでは、ベースラインが検出され、ピークが検出された時に積分される積分タイプ(Integration Type)があります。Baseline-to-baseline, Valley, Exponential skim, Exponential childです。

12/27/2018   

MultiQuant™ソフトウェアで監査証跡(Audit Trail)とセキュリティ機能をオンにすると他のプロジェクトフォルダーを参照できなくなります。

MultiQuant™ソフトウェアで監査証跡(Audit Trail)やセキュリティ機能をオンにすると、他のプロジェクトフォルダーを参照できなくなります。この記事には、そのことが記載されています。

12/27/2018   

Windows 10 と互換性のないSciex OS 1.3 のエラー "Services Cannot Launch"

この記事には、Windows 10 OSと互換性があるのは、SCIEX OSバージョン1.4とそれ以降であることが記載されています。SCIEX OS 1.3を起動しようとすると、サービスが開始できないことを示すエラーメッセージ「Services Cannot Launch」が表示される場合は、ソフトウェアがインストールされているOSを確認してください。

12/27/2018   

Six-Peptide Mixture (PN 4465940) のペプチド配列は?

この記事には、Six-Peptide Mixture(PN:4465940)に含まれる6種類のペプチドの配列情報が記載されています。

12/26/2018   

SCIEXキャピラリー等電点電気泳動法シャットダウンメソッド(Shutdown Method)におけるゲルリンスや水リンスの目的

この記事は、SCIEXキャピラリー等電点電気泳動法(cIEF)シャットダウンメソッド(Shutdown Method)において、水リンスに続いてゲルリンスをする目的について説明しています。目的は、キャピラリーを翌日すぐ使用できる状態にしておくことです。

12/05/2018   

GenomeLab™ GeXP 遺伝子解析システムを使用したDNA配列決定およびフラグメント解析のためのプライマーの純度について

GenomeLab GeXP 遺伝子解析システムまたはそれ以前のCEQ 遺伝子アナライザーでDNA配列決定やフラグメント解析のいずれかに使用するための核酸(DNA、RNA)プライマーをご注文される場合は、少なくとも固相抽出によって精製されたプライマーを選択してください。この記事には、そのことが記載されています。

11/30/2018   

テクニカルノート「Tech Bulletin IB-17031A」掲載の電荷不均一性分析のためのバッファーバイアルプレートマップ

SCIEXキャピラリーゾーン電気泳動(CZE)による電荷不均一性アッセイで使用されるプレートマップは、「Analysis of Monoclonal Antibody Charge Variants by Capillary Zone Electrophoresis (Beckman Coulter IB-17031A)」に掲載されている方法を設定する際に役立ちます。この記事には、そのことが記載されています。

11/15/2018   

aTRAQ™キットのサンプルや標準試薬はどのように保存すれば良いですか?

この記事には、aTRAQ™キットのラベリング試験に使用する試薬やサンプルの保存方法が記載されています。試薬やサンプルは、-20℃以下で保存してください。希釈液で溶解した内部標準は、小分けにして-70℃で保存してください。

11/13/2018   

LibraryView™ 1.0.1 ソフトウェアからライブラリーをエクスポートする方法

この記事には、LibraryView™1.0.1ソフトウェアからライブラリーをエクスポートする方法が説明されています。

11/12/2018   

MultiQuant™ MDソフトウェアでデータを解析するとChecksum Invalidエラーが表示される理由

MultiQuant™ MDソフトウェアでデータを解析しようとするとChecksum Invalidエラーが表示される理由は、Analyst MDソフトウェアのChecksum機能がオンの状態で取得されたデータを解析していないからです。この記事は、そのことについて記載しています。

11/09/2018   

ProteinPilot™ソフトウェアデータのPRIDE(PRoteomics IDEntifications)データベースへのエクスポート

この記事には、ProteinPilot™ソフトウェアデータをPRoteomics IDE Identifications(PRIDE)データベースにエクスポートするためのファイル変換の情報が記載されています。.groupファイルをXMLファイルに変換する必要があります。

11/09/2018   

Analyst®ソフトウェアのBatch Editor画面の「Plate Code」で66-バイアルプレートを表示させる方法

Analyst Device Driverは66-バイアルプレートをサポートしています。この記事には、、AnalystソフトウェアのBatch Editor画面で66-バイアルプレートを表示させる方法が記載されています。「Rack Code」を「2 Drawer Plates」に変更すると、「Plate Code」で66-バイアルプレート (66VialGen PlateRと66VialGenPlateC) が表示され、選択できます。

11/07/2018   

ProteinPilot™ソフトウェアにおける「Rapid」検索と「Thorough」検索の違い

この記事には、ProteinPilot™ソフトウェアの「Rapid」検索と「Thorough」検索の違いが説明されています。この選択で、検索アルゴリズムのどの部分を呼び出すか、また正しい答えを見つけるためにサンプルを効果的にどれだけ深く検索するかが決まります。

11/02/2018   

Analyst® のHardware ProfileにHPLCシステムなしでCDSオートキャリブレーションできるケース

この記事では、Hardware ProfileにHPLCシステムがなくてもCDSオートキャリブレーションシステムがアクティベートされていれば、Analystソフトウェアでデータ取得できるケースについて紹介しています。

11/02/2018   

在Analyst定量结果表中,怎样修改、保存和导出结果表设置

本文讲述如何修改(选择和调整可见纵列,改变有效数字和符号),保存并导出Analyst结果表

11/01/2018   

どのようにしてSCIEXソフトウェアをlaboratory information management system(LIMS)またはElectronic Laboratory Notebook(ELN)に接続できますか?

この記事は、SCIEXソフトウェアをLIMS / ELNと繋ぐインタフェースに使用できるオプションの説明です。

11/01/2018   

怎样把SCIEX软件接入到实验室信息管理系统(LIMS)或实验室电子记录系统(ELN)中

本文介绍了把SCIEX软件接入到实验室信息管理系统(LIMS)或实验室电子记录系统(ELN)的几个方法

11/01/2018   

Analyst TF 1.7.1において、SimモードのHardware ProfileをActivationする方法

この記事は、Analyst TF 1.7.1でSimモードのHardware Profile をActivationする方法について説明しています。追加ドライバー(Chronologicのndigoドライバー)をインストールする必要があります。

11/01/2018   

Analystにおいて、Result TableのTable Settingsを編集したり、保存したり、エクスポートする方法

この記事は、Analyst のResult TableのTable Settingsを編集(表示されるカラムの選択と調整、有効数字と表記の変更)したり、保存したり、エクスポートする方法について説明しています。

11/01/2018   

如何从岛津CBM内部为VIERROR找到错误日志

本文介绍了如何从岛津CBM内部为VIERROR找到错误日志

11/01/2018   

Shimadzu CBMからEvent Logに関するエラーログを取得する方法

この記事は、エラーの診断に役立つShimadzu Webサーバーへのアクセス方法の説明です。

11/01/2018   

Win 7 OSでコンピュータIDを見つける方法

この記事は、Win 7 OSでコンピュータIDを確認する方法について説明しています。

11/01/2018   

模拟模式(Sim Mode)下激活Analyst TF 1.7.1 的硬件配置

安装Chronologic Ndigo驱动可以让Analyst TF 1.7.1运行在模拟模式下。

11/01/2018   

LibraryView™ソフトウェア1.3へのライブラリパッケージのインポート手順

この記事には、ダウンロードしたライブラリパッケージ(.lpbファイル)をLibraryView™ソフトウェアにインポートする手順が説明されています。LibraryView™ソフトウェアの「Import」ボタンを選択し、適切なファイルタイプを選択します。

10/22/2018   

永久ライセンスがインストールされているはずのDiscoveryQuant™ソフトウェアで、期限切れのエラーメッセージが出る場合

この記事には、DiscoveryQuant™ソフトウェアを起動すると、永久ライセンスがインストールされているはずなのに、ソフトウェアの有効期限が切れたことを示すエラーメッセージが表示される場合の対応策が記載されています。

10/19/2018   

Analyst®ソフトウェアから出力するレポートに表示されるピークラベルが、MultiQuant™ソフトウェアで出力するレポートに表示されない

MultiQuant™ソフトウェアで出力するレポートにピークラベルを追加するには、レポートテンプレートの「Peak Review」に関するタグを編集します。この記事には、そのことが記載されています。

10/19/2018   

PPGチューニング中に一部のm/zにNAと表示される場合

Analyst®ソフトウェアでMSをチューニングおよびキャリブレーションしている時、明らかにイオンが検出されていても、キャリブレーションテーブルの一部のm/zにNAと表示されることがあります。この記事では、表示オプションの「Default Threshold」の変更方法について記載しています。

10/19/2018   

Analyst® ソフトウェアのデータファイル名の変更

Analyst®ソフトウェアのバッチ内でデータファイル名を変更し忘れたため、後でデータファイル(.wiffおよび.wiff.scan)名を変更したら、データファイルを開くことができなくなりました。この記事には、この問題を解決するヒントが記載されています。.wiffとwiff.scanファイルの名前は完全に一致させてください。

10/18/2018   

MultiQuant™ レポート時のエラー: System Out of Memory

この記事には、MultiQuant™ソフトウェアでレポート出力時に、「System out of memory」のエラーが表示される場合の解決策が記載されています。このエラーを解決するには、コンピューターにメモリーを追加するか、64-bitのコンピューターを使用するか、この記事で提案する2つの回避策を試してみてください。

10/18/2018   

IonDrive™ QJetイオンガイドをクリーニングするスワブのパーツ番号情報

この記事には、IonDrive™ QJetイオンガイドをクリーニングする帯電防止フォームスワブ(パーツ番号1017396または1017398)の情報が掲載されています。

10/18/2018   

MultiQuant™ソフトウェアのResult Tableに表示される可能性のある非数値の結果

MultiQuant™ソフトウェアでは、数値の代わりに数値以外の結果がResult Tableに表示されることがあります。この記事は、その数値以外の意味する内容について記載しています。

10/18/2018   

DuoSpray™ソースで内径25umのESIエレクトロードが使用できますか?

この記事には、内径25umのエレクトロードがIonDrive™Turbo VソースおよびDuoSpray™ソースで使用できることが記載されています。

10/17/2018   

ProteinPilot™ 5.0 .2ソフトウェアはWindows7 64-bitシステムで動作しますか?

ProteinPilot™ 5.0.2ソフトウェアは、現時点ではWindows 10 SP1 64-bitとMicrosoft Officeバージョン2016の組み合わせでのみ動作確認されています。しかし、Windows 7 64-bitでも動作します。この記事には、そのことが記載されています。

10/17/2018   

ProteinPilotソフトウェア4.5 BetaとMicrosoft Office 2016の互換性

この記事には、ProteinPilot™ソフトウェア4.5 BetaとMicrosoft Office 2016に互換性がないことが記載されています。

10/16/2018   

Analyst® 1.7ソフトウェアをWindows 10 OSへインストールする手順

この記事には、Analyst 1.7ソフトウェアをWindows10にインストールする2通りの手順が記載されています。1) SCIEXから購入したPCにインストールする手順、および2) SCIEXから購入したPC以外のPCにインストールする手順です。

10/16/2018   

iTRAQ® 試薬: 4-Plex試薬キットと8-Plex 試薬キットでラベルされた 両サンプルを混合できますか?

この記事は、iTRAQの4plex試薬キットと8 plex試薬キットに含まれるiTRAQ試薬の化学的構造の違いについて説明しています。SCIEXでは、この両iTRAQ試薬の化学的構造が違うため、別々のiTRAQキット、4plexおよび8plexの試薬でラベルしたサンプルの混合は推奨していません。

10/16/2018   

Analyst®ソフトウェアのQuantitation MethodにおけるAnalyte 名のフォーマット

この記事には、AnalystソフトウェアのQuantitation MethodでAnalyte 名を入力する時、ダッシュ(「-」)を使用しないほうがよい理由が記載されています。Quantitation MethodでAnalyteを正しくグループ分けするには、Analyte の名前と番号(数字)をスペースで区切ってください。

10/16/2018   

SCIEX OS 1.4ソフトウェアでLCの圧力をモニターまたは保存できますか?

現在、複数機種のHPLC装置のLC圧力をSCIEX OSソフトウェアでリアルタイムにモニターできます。保存することはできません。この記事には、そのことが記載されています。

10/16/2018   

Analyst®ソフトウェアの新しい登録キー(Registration Key)はどこで入手できますか。

この記事は、Analyst®ソフトウェアの新しい登録キー(Registration Key)の入手方法について説明しています。https://sciex.com/analyst-and-analyst-tf-key-generator-registrationから取得できます。

10/12/2018   

Analyst®ソフトウェアライセンスをインストールするために、Windows10で隠しフォルダーを表示する方法

この記事には、Analyst 1.7のライセンスファイルをインストールするために、Windows10 OSで隠しフォルダーを表示する手順が記載されています。

10/12/2018   

PepCalMixでは、どのアミノ酸が安定同位体ラベルされていますか?

PepCal Mix(P / N 5045759)には、20種類の安定同位体標識ペプチドが含まれています。安定同位体はアミノ酸KおよびRに標識されています。この記事には、PepCal Mix中の各ペプチドの配列と質量が記載されています。

10/09/2018   

Analyst® または Analyst® TF ソフトウェアは、下位互換性がありますか?

AnalystまたはAnalystTFソフトウェアは、上位互換性があります。下位互換性はありません。この記事には、そのことが記載されています。

10/08/2018   

MasterView™ ソフトウェアのレポートテンプレートはどこに保存されていますか?

この記事には、MasterView™ソフトウェアのレポートテンプレートが保存されている場所が記載されています。C:\Users\Public\Documents\AB SCIEX\MasterView\Templatesです。

10/08/2018   

サンプルのデータ取得が終わった後もNano LC/MS システムを稼働させ続ける方法

この記事には、サンプルのデータ取得が終了した後もNano LCシステムを稼働させ続けるために必要なEksigentとAnalystソフトウェアの設定方法が記載されています。Eksigent NanoLC400システムを使用すると仮定しています。

10/08/2018   

MALDI TOF/TOF 装置での組織イメージングに使用されるプレートテンプレート

LaserBio Labs™によるMass Spectrometry Imaging Starter Kitを使用するには、組織サンプルを123 mm x 81 mmのプレートホルダーに収まるブランクのLC MALDIプレートにマウントする必要があります。 この記事には、MALDIデータ取得用にカスタマイズされたプレートを作成するためのスターターテンプレートの情報が記載されています。

10/08/2018   

Analystでピークのテーリング部分の面積を除外するための積分パラメータの調整方法

この記事は、IntelliQuanダイアログのパーセントノイズパラメータを調整し、テーリングしているピークの面積を削る方法を説明しています。アナライトによっては、望ましくないピークテーリングを示す場合があります。そのテーリング部分を総ピーク面積から除外する必要があります。

09/06/2018   

MultiQuant®ソフトウェアのIon Ratioが一致しない場合の調整方法

この記事は、「Ion Ratio」の理由でMultiQuant®ソフトウェアのResult Tbaleにフラグが立つ場合について説明しています。

09/06/2018   

MultiQuant® 软件怎么修正离子比率Fail

如果离子比率在MultiQuant软件结果表中被标记,经常意味着峰积分的方法不一致。

09/06/2018   

在Analyst里修改积分参数以排除峰拖尾面积

有的分析物可能会出现拖尾现象,其中一些会需要从整个峰积分中排除拖尾面积。在IntelliQuan窗口下修改noise percentage参数可以有帮助。

09/06/2018   

SCIEX OS 1.4と共にインストールされるLibraryView™1.3ソフトウェアをサポートしているライセンスはどれですか?

SCIEX OS 1.4と共にインストールされたLibraryView™1.3ソフトウェアには、LibraryView 1.2のライセンスが必要です。この記事には、そのことが記載されています。

08/31/2018   

PeakView®ソフトウェアのSWATH Acquisition™MicroAppのライセンス有効期限情報の確認方法

この記事は、SWATH™ Acquisition MicroAppのライセンス有効期限情報の確認方法を説明しています。PeakView®ソフトウェアのHelpメニューから確認できるplug-insリストにSWATH™ Acquisition MicroAppは表示されますが、PeakView License Report画面には表示されません。

08/15/2018   

MultiQuant™软件中的Queries储存在哪里?

MultiQuant™软件后query存放在C:\ProgramData\AB SCIEX\MultiQuant\Queries

08/15/2018   

PeakView®软件中SWATH Acquisition™ MicroApp的许可信息

在PeakView®软件Help菜单中看license信息时,SWATH™ acquisition microapp的license信息在plug-ins list里面,而不是在PeakView的License Report页面

08/15/2018   

MultiQuant ソフトウェアのQuantitation Method(.qmethod)からアナライトを削除する方法

この記事には、MultiQuantソフトウェアのQuantitation Methodから不要なアナライトのMRMトランジションを削除する方法が記載されています。Quantitation Methodを開き、 「Delete Selected Rows」を選択します。

08/15/2018   

从MultiQuant定量方法(.qmethod)中删除化合物

删除MultiQuant 软件中的化合物MRM,需重新打开定量方法,选中化合物并删除。

08/15/2018   

CTCオートサンプラのカスタムサンプルトレイの作成方法

この記事は、CTCオートサンプラのカスタムサンプルトレイの作成方法について説明しています。

08/15/2018   

CTC自动进样器怎么增加自定义样品盘

如何配置CTC自动进样器以用于各种不同样品盘

08/15/2018   

Analyst® ソフトウェアで取得されたフォトダイオードアレイ(PDA)のデータはどこに保存されますか?

アナログデジタルコンバーター(ADC)を介してAnalystソフトウェアでWatersのフォトダイオードアレイ(PDA)のデータを取得した場合、データはAnalystのデータファイル(.wiff)に保存され、PeakViewソフトウェアで表示および解析することができます。この記事には、そのことが記載されています。

07/09/2018   

スペクトルの質をよくするために使用できる、Data Explorer Softwareのオプションについて

この記事は、Data Explorerソフトウェア4.11を使用してスペクトル品質を向上させる方法に関するいくつかのオプションについて説明しています。

07/09/2018   

Protein Preparation Kitの説明資料はどこに掲載されていますか?

この記事には、Protein PreparationKitの説明資料の掲載サイトの情報が記載されています。SCIEX Webサイト、https://sciex.com/Documents/tech%20notes/Protein-Preparation-Kit-Protocol.pdfまたはhttps://sciex.com/products/standards-and-reagentsにあります。

07/09/2018   

Data Explorer软件中有什么设置可以让我获得更好的质谱图?

本文介绍了在Data Explorer 4.11软件中提高谱图质量的几个方法

07/09/2018   

Analyst®ソフトウェアまたはMultiQuant™ソフトウェアのレポートテンプレートをSCIEXOSで使用できますか?

この記事には、Analystまたは MultiQuant™ソフトウェアで使用されていたレポートテンプレートが、クエリを含むMultiQuantテンプレートを除き、SCIEXOSで動作することが記載されています。

07/03/2018   

HPLC移動相添加剤としてのフッ化アンモニウム(AMF)の使用に関して

この記事は、フッ化アンモニウム(AMF)を移動相添加剤としてLC/MS用途に使用することについての情報です。 低濃度(約0.2 mM)のみのご使用を推奨します。

07/03/2018   

SCIEXソフトウェアのトライアルライセンスキーが届かない場合

トライアルライセンスキーを請求する時は、Sciex Webサイトへログインする為にユーザー登録したメールアドレスに間違いがないか確認してください。この記事は、そのことが記載されています。

07/03/2018   

「Status」カラムをAnalyst®ソフトウェアのQueueManager画面へ表示させる方法

「Status」カラムをAnalyst ソフトウェアのQueue Manager画面へ表示させるには、Queue Manager画面の任意のカラムを右クリックし、 「Column Settings」 を選択します。この記事には、そのことが説明されています。

07/03/2018   

SCIEX OSにおける同位体を含む化合物の分子量計算

SCIEX OSで同位体を含む化合物の分子量を計算するには、Explorerモードで「Mass Calculators」を選択し、開いた「Mass Property」タブで化学式を入力します。同位体については、元素記号の前に同位体の重さを入力してください。この記事には、そのことが説明されています。

07/03/2018   

SCIEXOS 1.4を1.3にダウングレードする手順

この記事には、SCIEXOS 1.4から1.3へのダウングレードの手順が記載されています。

07/02/2018   

SCIEX OS 1.4では、Queryを使用できますか?

SCIEX OS 1.4ソフトウェアのAnalyticsでは、Queryを使用できません。この記事には、そのことが記載されています。

07/02/2018   

他のSCIEXソフトウェアがインストールされていたPCへのSciexOS 1.4のインストール

SciexOS 1.4は、LibraryView™ Frameworkをバックグラウンドで使用し、ライブラリとライブラリサーチを管理しています。古いバージョンのフレームワークがPCにインストールされていると、1.4のインストールが失敗する可能性があります。また、古いバージョンのMicrosoft SQL Serverおよび.NET Frameworkがインストールされていても、インストールプロセスが失敗することがあります。この記事では、これら古いバージョンのツールを削除する手順について説明します。

07/02/2018   

MultiQuant™ソフトウェアのResults Table間でColumn Settings(カラム設定)を転送する方法

この記事には、MultiQuant™ソフトウェアのColumn Settings(カラム設定)をResults Table間で転送する方法が記載されています。Results Tableで右クリック、Column Settingsを開き、.csetファイル形式でエクスポートし、新しいResults Tableでこの.csetファイルをインポートします。

07/02/2018   

バッチモードで生データのスポットセットから.T2Dファイルをエクスポートする方法

この記事には、MALDIプレートに設定された生データのスポットセットからバッチモードで.T2Dファイルをエクスポートする手順が記載されています。「Program Files」、「Remote Data Access」、「JSW」内の「T2DExporter.exe」をインストールします。

06/04/2018   

.Wiff形式から.MgfファイルにMSデータを変換する方法

この記事は、.wiffデータを.mgfファイルの様な違う形式に変換するMS Data Converter(Beta1.3)ツールについての情報です。SCIEXのウェブサイトからダウンロードすることができます。

06/04/2018   

Analyst® Device Driver ソフトウェアでLCメソッドが開かない

この記事には、Analyst® Device Driver(ADD)でメソッドのLC部分が正常に開かない場合の解決策のヒントが記載されています。この問題を解決するには、プロジェクトフォルダー間でのファイルコピーを避け、Hardware Profileを再アクティベイトしてみてください。

06/04/2018   

MultiQuant™ソフトウェアにおいて、予想どおりにイオン比(Ion Ratio)が計算されない

MultiQuant™ソフトウェアにおいて、検量線ポイントにブランクのサンプルが含まれており、イオン比(Ion Ratio)の値が正しく表示されない場合があります。この記事には、その際の解決策が記載されています。

06/01/2018   

TripleTOF®システムによるペプチド分析における最適なコリジョンエネルギー(CE)

この記事は、ペプチド分析(タンパク質同定に用いるIDA測定およびSWATH Acquisition)に必要なコリジョンエネルギー (CE)値およびコリジョンエネルギースプレッド(CES)値は、AnalystTFソフトウェアに組み込まれているローリング CE(Rolling CE)機能を用いて最適化されることを説明しています。

05/31/2018   

カラム交換後のピーク形状のトラブルシューティング

分析カラムを交換した後、分析対象物のピーク形状が変化し、イオン比(Ion Ratio)が低下した場合、ガードカラムを交換すると、ピーク形状の問題が解決されることがあります。この記事は、そのことについて記載しています。

05/31/2018   

MALDI TOF / TOF™データのアーカイブとパージおよびデータベースバックアップの作成

この記事には、MALDI TOF/TOF™システムのデータをアーカイブ/パージする手順、並びにデータをバックアップする一般的な手順について記載しています。

05/31/2018   

Analyst®ソフトウェアにおいて、ネガティブモードで測定したExperiment情報をQuantitation Methodへ追加する方法

Analyst®ソフトウェアでポジティブモードとネガティブモードを切り替えてデータを取得し、ポジティブモードだけのQuantitation Methodを作成した場合、後からネガティブモードのExperimet情報を追加することができます。Quantitation Methodの「Data Source」のドロップダウンメニューを切り替えます。この記事は、そのことについて記載しています。

05/31/2018   

MultiQuant® ソフトウェアをインストールする時に発生する .NET Framemwork エラー

この記事には、MultiQuant 3.0 .2ソフトウェアをWindows XPにインストールする時に発生する 「An error occurred while installing system components for MultiQuant. Setup cannot continue until all system components have been successfully installed.」というエラーの解決策が記載されています。

05/31/2018   

MultiQuant™ソフトウェアをインストールする際は、管理者(Administrator)権限でWindowsにログインしてください

MultiQuant™ソフトウェアをインストールする際に、「The feature you are trying to access is unavailable. Cannot find license file/License File cannot be opened.」というエラーメッセージが表示された場合、このエラーを解決するには、管理者(Administrator)権限でWindowsにログインし、ソフトウェアとライセンスをインストールしてください。この記事は、そのことについて記載しています。

05/31/2018   

Analyst® 1.6 ソフトウェアにおける「Queue Options」の場所

この記事は、Analyst1.6.xソフトウェアで「Queue Options」を開く手順について説明しています。「Configure 」モードを選択し、「Tools 」メニューから「Settings 」、「Queue Options 」の順にクリックしてください。

05/25/2018   

Analystソフトウェアにおいて、データファイル(.wiff)名をスペースで始めることはできますか?

Analystソフトウェアのデータファイル(.wiff)名をスペースで始めることはできますか?答えは、Yesですが、ファイル名(.wiff)の先頭にスペースを入れることは推奨できません。この記事には、ファイル名の先頭にスペースを入れた場合の潜在的な問題について記載しています。

05/25/2018   

サンプルの注入量(Injection Volume)をAnalyst® ソフトウェアの Results Tableに表示できますか?

Analyst®ソフトウェアのResults Tableには、データファイルからサンプルの注入量(Injection Volume)の情報を表示するオプションはありません。この記事には、そのことが記載されています。

05/25/2018   

LibraryView™ ソフトウェア 1.1に化合物情報を追加する方法

この記事は、LibraryView™ソフトウェア1.1に化合物情報を追加する方法について記載しています。「Manage」画面で「Compounds」リストを展開し、化合物名を追加後、表示される指示に沿って操作ください。

05/21/2018   

MPX ソフトウェアのエラー: MPX Driver Is Not in the Active Analyst® Hardware Profile

MPXソフトウェアエラー、「MPX driver is not in the active Analyst® hardware profile 」を解決するには、AnalystソフトウェアのHardware Profileを作成し直してください。この記事には、そのことが記載されています。

05/21/2018   

Analyst®ソフトウェアでプロジェクトを作成できない場合

この記事には、Analystソフトウェアでプロジェクトフォルダーにアクセスできない場合の対応策が記載されています。ルートディレクトリをC:\ Analyst Data \ Projects \に設定する必要があります。 このルートディレクトリの下に追加のプロジェクトやサブプロジェクトを設定します。

05/21/2018   

Analyst® Device Driver 1.3のリリースノート

この記事は、The Analyst® Device Driver 1.3のリリースノートのダウンロードサイトについて記載されています。リリースノートには、旧バージョンからの新機能や変更点について記載されています。

05/21/2018   

Analyst®ソフトウェアのインストール中にNational Instruments GPIB Driverのエラーメッセージが表示された場合

この記事には、Analystソフトウェアのインストール中にNational Instruments GPIB Driverのエラーメッセージが表示された場合の対応策が記載されています。AnalystソフトウェアのインストールディスクのGPIBフォルダからドライバを手動でインストールしてください。

05/21/2018   

MultiQuant ソフトウェアでイオン比(Ion Ratio)を設定する方法

この記事には、MultiQuantソフトウェアのQuantitationメソッド(.qmethodファイル)で、イオン比(Ion Ratio)を設定する方法が記載されています。

05/21/2018   

Analyst®ソフトウェアのQuantitateモードにおいて、ピークの非対称性はどのように計算されていますか?

Analyst®ソフトウェアのQuantitateモードでは、ピークの非対称性を次の式で計算しています。 ((ピーク終了時間) - (保持時間)) / ((保持時間 - (ピーク開始時間))。この記事には、そのことが記載されています。

05/21/2018   

MultiQuant™ 2.0ソフトウェアでエラーメッセージ 「Feature Unavailable 」が表示される場合

この記事には、MultiQuant™ 2.0ソフトウェアライセンスをインストールしMultiQuant™ 2.0ソフトウェアを起動すると、エラーメッセージ「MultiQuant Feature Unavailable」が表示される場合の対応策が記載されています。 MultiQuan 2.0ライセンスで、MultiQuan 2.0ソフトウェアを起動させることはできません。正しいバージョン(2.0.2か2.1か2.1.1)のMultiQuantソフトウェアをインストールすると、この問題は解決します。

05/21/2018   

SCIEXの「Registered Software(登録ソフトウェア)」のWebページに、最近アクティブになったライセンスが一覧で表示されます。

この記事には、SCIEXの「Registered Software(登録ソフトウェア)」のWebページ(https://sciex.com/support/registered-software)が紹介されています。このページには、最近アクティブになったライセンスが一覧で表示されます。

05/21/2018   

Analyst® 1.7 ソフトウェア起動時のエラー : No Such Feature Exists

この記事は、Analyst®1.7ソフトウェア起動時にライセンスエラー「No such feature exists」が表示される場合の解決策について記載しています。C:\ProgramData\AB SCIEX\Analyst\Licenseフォルダーにライセンスファイルを保存すると問題が解決します。

05/16/2018   

ハイブリッドエレクトロードプの詰まりの原因

この記事には、ハイブリッドエレクトロードで報告されている一般的な詰まりの原因について記載しています。

05/15/2018   

ネットワーク経由で取得、解析・保存されたAnalyst®ソフトウェアのデータファイルのタイムスタンプ

質問1.Analystソフトウェアで取得したデータファイルをネットワークサーバーに保存する場合、データのタイムスタンプはローカルPCから取得されますか、それともネットワークサーバーから取得されますか?質問2.ネットワークサーバ上にあるAnalystのプロジェクトフォルダ内のデータを解析して、結果のファイルもネットワークサーバに保存しました。データのタイムスタンプは、ローカルPCまたはネットワークサーバのどちらから取得されますか? この記事は、これらネットワーク経由でデータを取得した場合やネットワーク上のデータファイルを解析した場合のタイムスタンプに関する質問に回答しています。

05/15/2018   

データファイルは、Analyst® ソフトウェアのプロジェクトフォルダー内の適切な階層(「Data」フォルダー)にコピーしてください。

Analystソフトウェアのデータやメソッドファイルをコピーする時のベストな方法は、プロジェクトフォルダーごとコピー&ペーストすることです。この記事には、そのことが記載されています。

05/14/2018   

Analyst® ソフトウェアのバッチに、更新した「Quantitation」タブ情報をインポートする方法

Analyst®ソフトウェアで、更新された「Quantitation」タブ情報をバッチにインポートするには、バッチファイルをテキスト形式でエクスポートし、その情報をExcelで編集します。この記事には、そのやり方が記載されています。

05/14/2018   

Analyst® ソフトウェアでは、クロマトグラムの軸設定を変更するオプションはどこにありますか?

Analyst®ソフトウェアには、クロマトグラムのX軸とY軸の設定に関するオプションがあります。この記事には、そのオプションの場所が説明されています。

05/14/2018   

Analyst®ソフトウェアで「Equilibrate」を選択しても、Shimadzu LCポンプが応答しない

この記事は、Analystソフトウェアにおいて、「Equilibrate」を選択してもShimadzu LCポンプが応答しない場合の解決策について説明しています。LCポンプを応答させるには、特定の起動手順に従い、システムがスタンバイ状態になったことを確認する必要があります。

05/14/2018   

Compound Optimization機能で化合物を最適化しようとQ1 MSスキャンをした際、分子関連イオンが検出されない

この記事には、Compound Optimization機能で化合物の最適化を実施しようと、インフュージョンによるQ1 MSスキャンをした際、化合物の分子関連イオンが検出されない場合のヒントが記載されています。移動相を添加したり、化合物の濃度を上げてみてください。

05/11/2018   

取得したデータファイルがAnalyst® ソフトウェアのプロジェクトフォルダー内の予想される場所にない場合

この記事には、Analystソフトウェアで取得されるデータは、データ取得時に選択されているプロジェクトに保存されることが記載されています。データを取得する前に、Analystソフトウェアで正しいプロジェクトが選択されていることを確認してください。 Analystソフトウェア画面の中央、上の段のプルダウンメニューに表示されているプロジェクトにデータが保存されます。

05/11/2018   

SCIEX Webサイトからソフトウェアをダウンロードするには、最新のブラウザをご使用ください。

SCIEX Webサイトからソフトウェアまたはトライアルライセンスを正常にダウンロードするには、ブラウザが最新である必要があります。この記事には、そのことが記載されています。

05/11/2018   

BioTool Kit MicroAppを使用するには、PeakView®ソフトウェアに別途ライセンスが必要ですか?

PeakViewソフトウェアでBioTool Kit MicroApp機能を使用するには、PeakViewライセンスと一緒にBioTool Kit MicroAppのライセンスをインストールする必要があります。この記事には、そのことが記載されています。

05/11/2018   

Analyst®ソフトウェアにおけるDADまたはUVクロマトグラムのピーク積分

この記事は、AnalystソフトウェアのQuantitateモードによるDADまたはUVクロマトグラムのピーク積分方法について説明しています。

05/11/2018   

WatersドライバとSCIEXソフトウェアの互換性ガイド

この記事は、WatersドライバとSCIEXソフトウェアの互換性について、付属のガイド「Waters tested Sciex Configuration Guide 」に記載されていることを説明しています。このガイドから、WatersドライバがAnalyst®ソフトウェアの特定のバージョンで動作するかどうかを確認してください。Waters UPLCのファームウェアがドライバパックまたはICSのバージョンと互換性があることを確認してください。

05/08/2018   

フルスキャン時のAnalyst®ソフトウェアにおけるHigh Mass Cooling

High Mass Coolingは、 Analystソフトウェアに導入された機能です。四重極ロッドに非常に高いRF電圧をかけることによる悪影響を最小限に抑えます。最適なイオントランスミッションと感度を維持しながら使用可能なマスレンジをわずかに広げるために、特定の装置(5500および6500シリーズのLow Mass モードのみ)でのみ使用されます。

05/04/2018   

Analyst®Device Driver 1.3 Tutorial

この記事は、Analyst Device Driver 1.3 Tutorialがデバイスドライバ使用のためのガイドであることを説明しています。このチュートリアルには、トラブルシューティングのヒントが含まれています。

05/03/2018   

Analyst® 1.7 ソフトウェアのライセンスエラー: Cannot find license file

Analyst1.7 ソフトウェアライセンスをアクティベートし、C:/ProgramData/AB SCIEX/Analyst/Licenseフォルダーへライセンスを保存したのに、ソフトウェアのアクティベートがうまく行かず、「Cannot find license file」というエラーメッセージが表示されることがあります。その場合は、ライセンスファイルの名前を「Analyst1.7.lic」に変更してください。この記事には、そのことが記載されています。

05/03/2018   

「Analyst® TF 1.7.1 Software with Components for LC Devices」のリリースノート

この記事には、「Analyst®TF 1.7.1 Software with Components for LC Devices」のリリースノートが、SCIEXホームページ(https://sciex.jp/software-support/software-downloads)に掲載されていることが記載されています。

05/03/2018   

Sciex OSでの定量解析で、保持時間(RT)を変更する方法

この記事には、Sciex OSでの定量解析において、グループ内のアナライトの保持時間(RT)を合わせる変更の仕方が記載されています。

05/03/2018   

Analyst 1.7ソフトウェアにおけるScheduled Ionization機能の設定

この記事は、Scheduled Ionization機能の紹介です。Scheduled Ionization機能は、コンタミネーションのリスクを軽減することによって装置のダウンタイムを短縮することに役立ちます。Analyst1.7ソフトウェアにおける設定方法を紹介します。

05/01/2018   

Analyst® 1.7ソフトウェアは、WindowsのLong-Term Service Channelに対応していますか?

Analystソフトウェアは、WindowsのLong-Term Servicing Channelに対応していません。この記事には、そのことが記載されています。

04/27/2018   

Analyst® 1.7 ソフトウェアのライセンスエラー: No Such Feature Exists. Feature: Analyst.acquisition

この記事には、Analyst1.7 のライセンスエラー「No such feature exists. Feature: Analyst.acquisition」を解決する方法が記載されています。解析用ライセンスがデータ取得用PCにインストールされている為に出るエラーです。ライセンスの入れ替えをしてください。

04/12/2018   

Analyst® 1.7 ソフトウェアの Installation Guide

この記事には、Analyst® 1.7 ソフトウェアの Installation GuideがインストールCDやファイルに添付されていることが記載されています。 PCにAnalyst 1.7ソフトウェアをインストールする前に、このガイドを必ず参照してください。

04/10/2018   

MultiQuant ソフトウェア3.0 .1の「Sum Multiple Ions」機能を使用するとピーク面積の合計値が合わない

MultiQuant™ 3.0.1ソフトウェアの「Sum Multiple Ion」機能を使用して、プリカーサーイオンを足し合わせることできます。この機能を使用した場合、同じイオンのXICピーク面積をExcelで合計した結果と数値は一致しません。この記事では、その理由を説明しています。

03/22/2018   

MultiQuant™ソフトウェアバージョン3.0.1から3.0.xへのアップグレード方法

この記事は、MultiQuant™ソフトウェアをバージョン3.0からバージョン3.0.1,3.0.2、または3.0.3にアップグレードするための手順について説明しています。

03/22/2018   

Analyst®ソフトウェアのExploreモードで複数の抽出イオンクロマトグラム(XIC)を重ね書きする方法

この記事は、AnalystソフトウェアExploreモードで、複数の抽出イオンクロマトグラム(XIC)を重ね書きする方法について説明しています。

03/22/2018   

Sciex OS でRack Changerをシミュレーションモードで設定する方法

この記事には、Sciex OSでRack Changerをシミュレーションモードで設定する方法が記載されています。

03/22/2018   

Multiquant 3.0升级到3.0.1 或 3.0.2

本文提供了从MultiQuant 3.0升级到MultiQuant 3.0.1和3.0.2的步骤。

03/22/2018   

Waters Method Editorで新しいタブを選択すると、Analyst®ソフトウェアを介してLCメソッドを作成する時に表示されるエラーが解決します。

Analyst®ソフトウェアを介してAcquity Method Editorにアクセスし、LCメソッドを作成する時、「ACQ-BSM」タブを選択するとエラーが発生します。この記事には、そのエラーの解決方法が記載されています。メソッドエディタ画面で、他のタブを選択することで解決できます。

03/16/2018   

MultiQuant™ソフトウェアでsMRMデータを解析するには、sMRM対応ライセンスが必要です

MultiQuant™ソフトウェアでsMRMデータを解析するには、sMRM対応ライセンスが必要です。この記事には、そのことが説明されています。

03/16/2018   

LibraryView™ソフトウェアのライブラリーライセンスは、どこにインストールされていますか?

この記事では、LibraryView™ソフトウェアのライブラリーをインストール後に、ソフトウェアで表示できない場合の確認事項が記載されています。ライブラリーライセンスの保存場所を確認してください。C:\Program Files\AB SCIEX\LibraryView\binに保存する必要があります。

03/16/2018   

SCIEXソフトウェアはどこからダウンロードできますか?

この記事には、SCIEXの多くのソフトウェア(フルバージョン)は、SCIEXのウェブサイト https://sciex.jp/software-support/software-downloads からダウンロードできることが説明されています。

03/16/2018   

ProteinPilot™ 5.x ソフトウェア: .groupファイルに設定した装置と違う装置名が出力される場合

この記事には、ProteinPilot™ソフトウェアから出力される.groupファイルに誤った質量分析装置が表示される場合の対応策が記載されています。TripleTOF 5600システムを選択して解析したにも関わらず、.groupファイルのシステム情報にQSTAR Eliteという名前が表示されることがあります。その場合、誤った装置のトレランス設定が適用されている可能性があります。

03/16/2018   

Analyst® ソフトウェアでのCalibration Reference Tableの復元

AnalystソフトウェアでCalibration Reference Tableを復元するには、TuneData.tunファイルのコピーを現在のAPI Instrumentフォルダー> Preferencesフォルダーに移します。この記事には、その手順が記載されています。

03/15/2018   

Analyst® ソフトウェアで1つのPeriod内に2つのExperimentを設定したメソッドを用いて取得したデータの表示方法

この記事では、Analyst®ソフトウェアで1つのPeriod内に2つのExperimentを設定したメソッドを用いて取得したデータの見方を説明しています。

03/15/2018   

MS3測定において、対象イオンに隣接する2つのピークも選択される理由

この記事は、MS3測定で機能するAF2(共鳴励起場の振幅を表すパラメータ)の影響について記載しています。AF2が非常に大きい場合には、非共鳴励起が隣接するm/zイオンの運動エネルギーを増加させます。

03/15/2018   

Analyst® 1.7 Patch for Windows 10 Update 1709インストール時のエラーについて

この記事は、Analyst® 1.7 with Hotfix 1とAnalyst 1.7 Patch for Windows 10 Update 1709をインストールする際に出るエラーメッセージについて説明しています。「You must have Analyst 1.7 software installed to install Analyst 1.7 Patch for Windows 10 Update 1709.」というエラーメッセージが表示されることがあります。

03/14/2018   

ディバーターバルブのタイムプログラムが組まれていないことによるAnalyst®ソフトウェアのScheduled MRMメソッドでのデータ取得の失敗

Analystソフトウェアで作成されたScheduled MRM(sMRM)メソッドは、メソッド構成にディバーターバルブがあるとデータ取得の開始に失敗することがあります。 バルブにタイムテーブルが組まれていること、またはメソッド構成から除外されていることを確認してください。この記事には、そのことが記載されています。

03/14/2018   

Windows10におけるAnalyst®1.7ソフトウェアインストール時のエラー

この記事は、Windows 10 OSにおいて、Analyst 1.6.3からAnalyst 1.7にアップグレードしようとする時に発生するエラーについて説明しています。このエラーが出るとAnalyst 1.7ソフトウェアのインストーラーが起動しません。以前のバージョンのAnalystソフトウェアをアンインストールし、Analyst 1.7 with Hotfix1を単独でインストールする必要があります。

03/14/2018   

Analyst®ソフトウェアでShimadzu30AC Autosamplerのニードル外リンスメソッド(External Rinse Method)で設定する項目の定義

Shimadzu30ACオートサンプラーでは、外部リンス機能は、リンスポンプによってリンスポートに押し込まれた溶液を使用してニードルの外部をすすぎ、洗浄します。Analyst®ソフトウェアでLCMSのAcquisition Methodを構築する場合、 「Autosampler」 タブの 「Flow Channel Reference...」 ボタンからリンスメソッド設定項目の定義画面にアクセスできます。

03/13/2018   

サマータイムへの自動タイムシフトによりMPX™ソフトウェアのバッチが停止する

MPX™ソフトウェアがバッチをSubmitしている間に、コンピュータの時計がサマータイムに合わせて更新されると、データが破損したりバッチが停止したりする可能性があります。時間が自動更新されないように設定してください。この記事には、その方法が記載されています。

03/12/2018   

Analyst®ソフトウェアのSecurity Configurationへユーザーグループを追加する方法

この記事は、AnalystソフトウェアのSecurity Configurationにユーザーグループを追加する方法について説明しています。

03/08/2018   

Analyst®ソフトウェアの「Security Configuration」で設定するRoleごとにWindowsユーザーグループを作成する方法

Windowsユーザーグループは、Analystソフトウェアの「Security Configuration」で設定されたRoleごとに作成します。この記事は、そのWindowsユーザーグループの作成方法について説明しています。

03/08/2018   

2つのデータを1つのデータファイルに取得した場合、ProteinPilot ソフトウェアではこのデータを解析することができません。

2つのデータを1つのデータファイルに取得した場合、ProteinPilotソフトウェアではこのデータを解析することができません。この記事には、そのことが記載されています。ProteinPilotソフトウェアで解析したいデータは、1つのデータファイルに重複してデータを取得せず、1データファイルに1データで取得してください。

03/07/2018   

MultiQuant™ ソフトウェアのエラー : Currently Running in Another Windows Session

この記事には、MultiQuant™ソフトウェアのエラー「Currently running in another Windows session on this computer. Switch to the other session and close the software」を解決する方法が記載されています。 Analyst、MultiQuantを両アカウントでシャットダウンし、そしてAnalyst Servicesもシャットダウンします。その後、1つのアカウントでソフトウェアを再起動してください。

03/07/2018   

AnalystソフトウェアでY軸を固定値に設定できますか?

AnalystソフトウェアのExploreモードでは、y軸を固定することはできませんが、リンクさせたクロマトグラムのy軸、x軸を拡大させる時に使えるオプションがあります。QuantitateモードのResult Tableでは、y軸を固定してピークをレビューする方法があります。この記事は、そのことについて説明しています。

03/06/2018   

BioPharmaView™ ソフトウェア: ジスルフィド架橋(SS結合)とシステイン修飾の同時解析はできません。

BioPharmaView™ソフトウェアによるジスルフィド結合マッピングは、User Guideに記載されています。しかし、システイン修飾解析に加えて同時にジスルフィド架橋のテーブルを作成することは記載されておらず、行うことができません。この記事には、そのことが記載されています。

02/26/2018   

MarkerView™ 1.2.1 and 1.3 software and PeakView® 2.2 software can import T2D files generated on the TOF/TOF™ series of instruments.

02/26/2018   

TripleTOF®システムにおける四重極のイオントランスミッションの仕組み

TOFMSでは、全てのイオンがRFモードでQ1を通過します。一般的に、Q1およびQ2の中をイオンは、質量範囲に応じた軌道を移動し、適切なイオン群がTOF分析部へ送られます。ここでのQSTARシステムに関する一般的な説明は、TripleTOFシステムにも当てはまります。

01/31/2018   

データ解析後のChemoView™ ソフトウェアのエラー: Programmatic Access To Visual Basic Project Is Not Trusted

データ解析後のChemoview™ソフトウェアのエラー「Programmatic access to Visual Basic project is not trusted」は、オートメーションクライアントからVBAオブジェクトモデルへのアクセスをオンにすることで解決します。この記事には、そのことが記載されています。

01/12/2018   

Analyst®TFソフトウェアで構築するAcquisition MethodのPulser Frequencyの確認方法

一般的にPulser Frequencyは、AnalystTFソフトウェアのAcquisition Method内で設定する質量範囲に応じて自動的に計算されます。この記事は、Pulser Frequencyの値を確認する方法について記載しています。

01/12/2018   

Analyst®ソフトウェアでピークのポイント数を調べるための2つの方法

この記事は、Analystソフトウェアでピークのポイント数を知る2つの方法について説明しています。1) View→Graph Informationで行う方法と、2) Tools→Settings→Appearance Options→Other Graph Option→Chromatogramの下段をYes (with scan number )にする方法があります。

01/11/2018   

Shimadzu AAOを使用する場合、Analyst®ソフトウェアでPDAまたはUV-Visデータをリアルタイムに確認できません

Shimazu LCシステムのダイオードアレイまたはUV-vis検出器をAAO制御で使用する場合、AnalystソフトウェアでリアルタイムにPDA又はUV-visデータを表示することはできません。この記事には、そのことが説明されています。

12/22/2017   

Compound Optimization時に設定できるコリジョンエネルギー(CE)の最大値

この記事は、AnalystソフトウェアによるCompound Optimization時に使用できるコリジョンエネルギー(CE)値の最大値について説明しています。130です(ソフトウェアのParameter SettingsでCEの最大値を180に設定できたとしても)。

12/22/2017   

SupervisorのセキュリティRole(役割)が割り当てられていると、なぜAnalystソフトウェアを開けないのですか?

AnalystソフトウェアでSupervisorのセキュリティRole(役割)を割り当てられているユーザーは、Analystのセキュリティ設定がMixedモードに設定されている場合に限り、画面ロックや自動ログアウトを解除できます。この記事には、そのことが説明されています。

12/22/2017   

Win 7 64-bitシステムに必要なLibraryView™ソフトウェアのバージョンは何ですか?

この記事には、Windows 7, 64-bitシステムにインストールできるLibraryView™ ソフトウェアのバージョンが記載されています。LibraryView™ ソフトウェア1.0.2以降です。

12/21/2017   

トライアルライセンスを永久ライセンスに置き換える方法

ソフトウェアを開く時に、永久ライセンスがインストールされていると思われる場合でも、ライセンスが期限切れであることを示すエラーメッセージが表示されることがあります。この記事には、その場合の対応策が記載されています。トライアルライセンスを削除し、永久ライセンスをインストールします。

12/21/2017   

Analyst®ソフトウェアにおけるコリジョンエネルギー(CE)のデチューニング(Detuning)

この記事は、Analystソフトウェアを使用したTriple Quad™5500システムによるデータ取得中にシグナルがサチュレーション(飽和)しているように見える場合の検討策について説明しています。各MRMトランジションに対して最適ではないコリジョンエネルギー(CE)値を使用してみてください。

12/21/2017   

SCIEX OS 1.3と一緒にインストールされるLibraryView™1.2ソフトウェアには、どのソフトウェアライセンスを使用しますか?

SCIEX OS 1.3と一緒にLibraryView™1.2ソフトウェアをインストールする場合は、LibraryView 1.0ライセンス(PN 5022277)を使用してください。この記事には、そのことが記載されています。

12/21/2017   

監査証跡(Audit Trail)のイベントを電子メール通知させるAnalyst®ソフトウェアの設定

1日の内に3回以上のログオンエラーが発生した場合に、電子メール通知で知らせてくれるようAnalyst®ソフトウェアで設定することができます。 この記事には、その設定方法が記載されています。この電子メール通知は、Analystソフトウェアの設定が「Integrated Mode」または「Mixed Mode」の場合にのみ利用可能です。

12/21/2017   

Analyst®ソフトウェアでManual Tuneモードを使用している時に、内蔵シリンジに関するエラーメッセージが表示される場合

Analyst®ソフトウェアのManual Tuneモードにおいて、化合物の最適化を実施していると「The current sample cannot be run because the syringe pump has stalled. The syringe plunger may be stalled in the syringe barrel.」というエラーメッセージが表示されることがあります。この記事には、解決策が記載されています。この問題を解決するには、シリンジホルダーを元に戻してエラーをクリアしてください。これでうまくいかない場合は、シリンジを交換するか、必要であればMSをリセットしてください。

12/21/2017   

QTRAP® 6500システムでは、どのようなカーテンガス設定を使用する必要がありますか?

この記事は、QTRAP®6500システムでのカーテンガスの上限値について説明しています。上限値は50 psiです。カーテンガスの設定は40〜45 psiを超えないように設定します。

12/21/2017   

Analyst®ソフトウェアでサンプルデータを取得するためには、Shimadzuオートサンプラーのラックが正しく設置されている必要があります

この記事は、Analystソフトウェアにおけるデータ取得時や平衡化時のShimadzu LCコントローラーエラーの原因の可能性について説明しています。オートサンプラーラックがオートサンプラーハウジングに正しく取り付けられていないことが原因である可能性があります。

12/21/2017   

Analyst®ソフトウェアのManual Tuneエラーを解消する方法

AnalystソフトウェアのManual Tuneモードでインフュージョンによる化合物の最適化を実施している際にシリンジが空になった場合、Manual Tuneエラーが表示され、最適化が中断されることがあります。LC / MSシステムのリセットが必要になる場合があります。この記事には、そのことが記載されています。

12/21/2017   

SCIEXはWindows 10に対応したAnalyst®やMultiQuant™ソフトウェアのバージョンがありますか?

Analystソフトウェア 1.7とMultiQuant ソフトウェア3.0.3はWindows 10と互換性があります。

12/20/2017   

Analyst®ソフトウェアへのWaters Acquityプレート設定の追加方法

この記事は、Waters Acquity96well,1mLプレート((ANSI-96well1mL.plate file)設定をAnalystソフトウェアに追加する方法について説明しています。Watersからプレート設定ファイルを入手する必要があります。

12/20/2017   

Analyst®ソフトウェアにおける連結された.wiffファイルの分離について

連結された.Wiffファイルを分離するには、 「Make Subset File」 というスクリプトが使用できます。 このスクリプトは、ファイル内のExperimentに依存するため、動作に制限があります(スクリプトはIDAメソッドでは機能しません)。このスクリプトは、Analyst TFソフトウェアCDの\Extras\Scripts\Make Subset Fileフォルダーにあります。AnalystソフトウェアCDの場合は、\Install\Scripts\Make Subset Fileフォルダーにあります。

12/20/2017   

Sciex OSソフトウェアでサービスパッケージを作成する方法

この記事には、Sciex OSソフトウェアで、イベントログなどを含むサービスパッケージを作成する方法が記載されています。「Configuration」、「About」、「Generate a Support Package」の順に選択します。

12/20/2017   

SWATH™ Acquisition のVariable Window Calculator v 1.0は、TripleTOF® システム全機種で使用できますか?

SWATH™ AcquisitionソフトウェアのVariable Window機能はTripleTOF 4600、5600、6600システムで動作しますが、AnalystTF 1.7ソフトウェアをインストールする必要があります。この記事には、そのことが記載されています。

12/15/2017   

サンプル測定をスタートさせた直後にエラーが検出された場合に考えられる原因の可能性について。エラーメッセージ:Shimadzu LC Controller Device Fault Detected

この記事は、AnalystソフトウェアのQueue画面でサンプル測定を開始した直後にエラーが検出される場合の原因の可能性について説明しています。LCMSシステムの設定で問題がないと思われる場合は、Shimadzuオートサンプラーのラックがオートサンプラーのハウジングに正しく取り付けられているかを確認してください。

12/14/2017   

SCIEX Webサイトへのログインには、E-メールアドレスの確認が必要です。

SCIEX Webサイトへのログインするアカウントを作成すると、E-メールアドレスの確認を求められます。アカウントを作成した後に表示されるWebページ、またはSCIEX Now™から送信されたEメール内のリンクをクリックし、SCIEXでオンラインアカウントを有効にしてください。この記事には、そのことが記載されています。

12/14/2017   

MultiQuant™ ソフトウェアでレポーターを実行している際の エラー:「Column Name Conflict 」

この記事には、MultiQuant™ソフトウェアでレポーターを実行している時にエラーメッセージ「The column name;ion type; conflicts with an existing column」が表示された場合の解決策が記載されています。このエラーは、レポートテンプレートでクエリが使用されていて、レポート処理の途中で中断され、MultiQuantのResults Tableにいくつか追加のカラムが残っていることが原因で発生します。

12/14/2017   

LISシステムで読み取る為のAnalyst® Report Template:なぜLISシステムはデータの最初の行から先を読み取らないのか?

Analystソフトウェアのレポートテンプレートを使用して出力したCSVファイルをLISシステムで読み取る場合、データ値のないセルが含まれていると、LISシステムは空のセルから先を読み取ることができません。LISが出力ファイル全体を確実に読み取るには、CSVファイルの各セルに何らかの値が含まれている必要があります。この記事には、そのことが記載されています。

12/14/2017   

TripleTOF®およびX500システムにおけるインタクトプロテイン分析では、何をキャリブラント溶液に使用しますか?

この記事には、TripleTOF®およびX500システムにおけるインタクトプロテイン分析で使用するキャリブラント溶液について記載しています。

12/14/2017   

SCIEX OSで解析したUVと MSの両データを含むResults TableをSCIEX OSで開く

この記事には、SCIEX OS でMSとUVの両データが含まれているデータファイル(.wiff2)を解析し、作成されたResults Tableをエラーメッセージ「Error. Cannot be empty, Parameter name: experiments」なく開く方法が記載されています。

12/13/2017   

Analyst®ソフトウェアにおけるバッチ作成時の*.xlsxファイルのインポートに関して

この記事には、Analystソフトウェアでバッチを作成する際、*.xlsxファイルをインポートするには、Microsoft Office 32-bitのインストールが必要であることが記載されています。Win7 64-bit OSで32-bitバージョンのOfficeを使用することは推奨できません。SCIEXでは、xls、.csv、.txt形式のファイルを使用することを推奨します。

12/13/2017   

Analyst® TF Software 1.7.1 のパッチ:Analyst® TF 1.7.1 Patch for Noise Sync Signal Issue

AnalystTFソフトウェア1.7.1では、たまにデータ取得に失敗し、アプリケーションのLogファイルに「Noise failing sync signal ignored. (ATF-665, -TDC error) 」という警告が表示されることがあります。この問題に対処するパッチがあります。この記事は、そのことについて記載しています。

12/13/2017   

MultiQuant™ソフトウェアエラー: "Update Column Settings Failed"

この記事は、MultiQuant™ソフトウェアでエラーメッセージ「Update Column Settings Failed. Object reference not set to an instance of an object」が表示された場合について説明しています。これは、メモリリークの問題が原因で起こり、プログラムを閉じて再オープンすることで解決できます。

12/13/2017   

Acquity AAO Serviceが開始しない場合

この記事は、Waters Acquity AAO Serviceが開始されずエラーが表示される場合の一つの解決策として、AAOファイルのサービスプロパティを編集する手順について説明しています。エラー:"Cannot start service from the command line or a debugger. A Windows Service must first be installed (using installutil.exe) and then started with the Server Explorer, Windows Services Administrative Tool or the NET START command."

12/11/2017   

MultiQuant软件新安装后运行时显示License不被支持

MultiQuant软件新安装后运行时显示License不被支持,这与安装时勾选Audit Trail / Security有关

12/11/2017   

MultiQuantをインストール後、ソフトウェアを起動すると、「License not supported」と表示される場合

After a new MultiQuant™ software installation, the error message, "License not supported" is displayed.

12/11/2017   

MultiQuant™ソフトウェアの監査証跡(Audit Trail)およびセキュリティ機能を使うには、ベースバージョンライセンスと拡張機能ライセンスが必要

この記事には、MultiQuant™ソフトウェアと監査証跡(Audit Trail)およびセキュリティの拡張機能ライセンスをインストールすると、ソフトウェアが起動せず、「This feature is not licensed. It cannot be used.」というエラーメッセージが表示される場合の解決策が記載されています。MultiQuantベースバージョンライセンスとともに、監査証跡(Audit Trail)およびセキュリティの拡張機能ライセンスをインストールする必要があります。

12/11/2017   

フォトダイオードアレイ (PDA)を搭載したExion LCとAnalyst®ソフトウェアで平衡化ができない場合

フォトダイオードアレイ(PDA)検出器を搭載したExion LCシステムがAnalystソフトウェアとコミュニケーションできない場合があります。この記事は、その解決策について記載しています。Hardware Profileを再Activateし、それでも改善しない場合はAnalyst Servicesを再起動してください。

12/11/2017   

Analyst ソフトウェアを再インストールする前にバックアップが必要なファイル は何ですか?

この記事は、Analystソフトウェアを再インストールまたはアップグレードする前に、バックアップが必要なフォルダーについて記載しています。

12/11/2017   

製品安全データシート(MSDS)または試験成績書(CoA)はどこから入手できますか?

この記事は、SCIEX試薬の製品安全データシート(MSDS)や試験成績書(CoA)の入手方法について説明しています。https://sciex.com/tech-regulatory?safetyTerm=4406127&amp;safetyLanguage=English-United+Statesに掲載されています。

12/11/2017   

MultiQuant™ ソフトウェアの 解析メソッド(Quantitation Methods)における保持時間(Retention Times)の更新方法

この記事は、MultiQuant™ソフトウェアのQuantitation Methodsの保持時間(RT)を更新する方法について説明しています。

12/11/2017   

新しく測定化合物を追加した場合のAnalyst®ソフトウェアまたはMultiQuant™ソフトウェアのQuantitation Method(定量解析メソッド)の更新に関して

この記事は、新しい化合物をAcquisition Methodに追加した場合、Analyst®ソフトウェアまたはMultiQuant™ソフトウェアのQuantitation Method(定量解析メソッド)も更新する必要があることについて説明しています。

12/08/2017   

iTRAQ®プロトコールの陽イオン交換クロマトグラフィーのヒントとコツ

iTRAQプロトコールで説明されている陽イオン交換のマニュアル注入操作では、2インチニードルの付いた22ゲージのシリンジ(別売)が必要です。 この記事では、iTRAQ試薬でラベルしたサンプルを陽イオン交換カラムに通す際のヒントとコツを紹介しています。

12/08/2017   

Analyst回归方程

本文档总结了Analyst定量计算的线性方程

12/04/2017   

Analystの検量線回帰式について

この記事は、Analystが定量に使用する回帰曲線を計算する式をまとめたものです。

12/04/2017   

Eksigentカラムのパーツ番号はどこにありますか?

この記事には、Eksigentカラムのパーツ番号が掲載されたリンク先情報が記載されています。 リンク先には、Nano cHiPLCカラムを含む全てのEksigent のMicroカラムとNanoカラムが掲載されています。

12/01/2017   

BioPharmaView™ ソフトウェア 2.1のペプチドシーケンスセクションのスコアーはどのように決まりますか?

BioPharmaView™ソフトウェアでペプチド消化物を解析後、各ペプチドが表に表示されます。 理論的タンパク質分解消化物と比較し、各ペプチドにスコアーが付きます。この記事には、そのスコアーを決める2つの要素について記載しています。

12/01/2017   

MaxQuantソフトウェアはどこでダウンロードできますか?

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

12/01/2017   

エクセルで再計算された濃度が、AnalystのCalculated Concentrationと合わない理由

この記事は、エクセルで再計算された濃度が、AnalystのCalculated Concentrationと合わない理由について説明しています。AnalystのResult Tableの結果からExcelで再計算すると、結果は正確には合いません。なぜこれが起こり、どうすればこれを避けられるかについて説明しています。

11/29/2017   

Shimadzu LCのソレノイドバルブ(Solenoid Valve)または移動相切り替えバルブ(Solvent Selection Valve)の設定方法

この記事は、Shimadzu LCシステムのFCV-11 ALバルブを設定する方法について説明しています。

11/22/2017   

Data Converter Version 1.3 Betaでデータファイルの処理に失敗する原因

この記事には、SCIEX MS data converter version 1.3 betaが正しく動作しない原因の可能性について記載しています。

11/22/2017   

MultiQuant™ソフトウェアは、sMRM対応機能が追加されたライセンスだけでは、起動しません。

MultiQuant™ ソフトウェアでsMRMデータを解析するには、二つのライセンスが必要です。一つがベースバージョンライセンスで、もう一つがsMRM対応機能が追加されたライセンスです。この記事には、そのことが記載されています。

11/22/2017   

MutliQuant™2.xとMultiQuant 3.xソフトウェアを同じPCに共存させることは可能ですか?

この記事は、 MutliQuant™2.xとMultiQuant 3.xソフトウェアを同じPCに共存させることは可能かどうかを説明しています。共存はできません。

11/22/2017   

Manual Tuningモードで操作の際、PPG のリファレンスピークリストが表示されているテーブルが見つからず、開くことができない

この記事は、Manual Tuningモードで操作の際、Analystソフトウェアで「Calibration Peak Lists」を表示する方法について説明しています。「Tools」メニューから「Settings 」→「Appearance options」→ 「Miscellaneous 」へ進み、「Show Mass calibration peak list」にチェックを入れます。

11/22/2017   

Analyst®ソフトウェアのResults Tableにおいて、面積積分を手動又は自動で変更した場合は、「Apply」や「Accept」を押す必要があります。このプロセスを簡単にすることはできますか?

この記事では、Analyst ®ソフトウェアの監査証跡(Audit Trail)設定において、手動積分の場合は全て「Accept」を押す必要がありますが、監査証跡(Audit Trail)が不要な場合は、AnalystソフトウェアのAudit Mapを「No Audit Trail」に設定し、自動積分時の「Apply」を省けることが説明されています。

11/15/2017   

激活Markerview 1.2.1.1软件,需要激活码而不是License文件

安装了Markerview 1.2.1.1软件后,需要激活码而不是License文件。激活码可以通过email metabolomics@sciex.com来取得。

11/14/2017   

Markerview 1.2.1.1を有効にするには、ライセンスファイルではなく、アクティベーションキーコードが必要です

この記事は、Markerview1.2.1.1をインストールし、ライセンスアクティベーションをする方法について説明しています。ライセンスアクティベーションには、ライセンスファイルではなく、アクティベーションキーコードが必要です。 ソフトウェアアクティベーションキーコードは、metabolomics@sciex.comに電子メールで依頼し入手できます。

11/14/2017   

Skylineソフトウェアとはどんなソフトで、どんなデータファイルが読み込めますか?

この記事は、Skylineソフトウェアの機能の一般的な説明と、Skylineで動作するSCIEX装置のデータ形式について説明しています。

11/10/2017   

SWATH® Acquisition Performance Kit内のPepCalMixペプチドを調製するためには酢酸が必要です

この記事では、SWATH Acquisition Performance KitのPepCalMixを5%酢酸ではなくギ酸を使用して調製した際の問題について説明しています。

11/09/2017   

ChemSpiderソフトウェアのトークンを取得する方法

この記事は、Sciex OSソフトウェアでChemSpider ソフトウェアのトークンを取得する方法について説明しています。Sciex OSソフトウェアのFormula Finder Settingsパネルは、ChemSpiderサービスを選択した後でChemSpiderセキュリティトークンを要求します。 トークンを取得するには、ユーザーがChemSpiderのWebサイトに登録する必要があります。

11/08/2017   

LC/MS Peptide Calibration Kitに含まれているβガラクトシダーゼの全アミノ酸配列

この記事は、LC/MS Peptide Calibration Kit(製品番号4465867)に含まれているβガラクトシダーゼの情報について説明しています。βガラクトシダーゼ(製品番号4465938)の全アミノ酸配列はFASTAファイルフォーマットで提供されています。 この製品(製品番号4465938)には、1バイアルのβガラクトシダーゼ消化物(625 pmol /バイアル)が含まれています。

11/02/2017   

Analyst®ソフトウェアのAudit Trailのアーカイブ場所

この記事は、Analyst®ソフトウェアのAudit Trailのアーカイブ場所について説明しています。Analyst®ソフトウェアのInstrument Audit TrailまたはProject Audit Trailが1000レコードに達すると、ファイルがアーカイブされたことを示す最後のレコードが追加されます。 監査証跡は、監査証跡のタイプと日付と時刻を示す名前とともにProject Informationフォルダに自動的に保存されます。

10/31/2017   

MPX™ DriverソフトウェアのEvent Logファイルの保存場所

MPX™ DriverソフトウェアのEvent Logは、Program DataのMPX DriverフォルダーのLogフォルダーにあります。この記事には、そのことが記載されています。

10/31/2017   

Analyst®ソフトウェアでIon Libraryを作成する方法

この記事は、Analyst®ソフトウェアでIon Libraryを作成する方法についてのコメントです。

10/30/2017   

Explore モード において「Extract Ions 」表示の際、自動的にクロマトグラムやスペクトルを重ねて表示する方法

この記事は、Explore モード において「Extract Ions 」表示の際、自動的にクロマトグラムやスペクトルを重ねて表示する方法について説明しています。

10/23/2017   

「Injection volume must be a positive value」というエラーメッセージが表示される場合

Analyst ソフトウェアがインストールされているデータ取得用PCの地域設定が英語(US English)に設定されていない場合、BatchのSubmit時に「Batch not submitted-Injection volume must be a positive value」というエラーメッセージが表示されることがあります。この記事は、そのことについて記載しています。

10/23/2017   

ExionLC ADのオートサンプラーからカラムオーブンへの配管チューブの部品番号は?

この配管チューブは、サービスパーツとしてご購入頂けます。

10/23/2017   

ChemoView 2.0.3 ソフトウェアで「Manage」画面がグレーアウトしている場合

この記事には、ChemoViewソフトウェアにログインした後、「Process」画面にのみアクセスでき、「Manage」画面がグレーアウトする場合の解決策が記載されています。Analystソフトウェアの「Security Configuration」モードですべてのユーザーを管理者(Administrator)に変更することで解決します。

10/20/2017   

MultiQuant™ ソフトウェアがライセンスのインストール後に起動しない場合

MultiQuant™ソフトウェアがインストール後に起動せず、エラー「Result Code:-1 Cannot find license file…」が表示されることがあります。この問題を解決するには、Cドライブの「Program Files」にフルアクセスできる管理者権限でWindowsにログインする必要があります。この記事には、そのことが記載されています。

10/17/2017   

T-infusionを使用してマニュアルチューニングする方法

この記事は、イオン源やガスパラメータを最適化するT-infusionの準備方法について説明しています。

10/13/2017   

MultiQuant™ソフトウェアでPosi/NegaスイッチングのScheduled MRM™データが開かない

この記事には、Posi/NegaスイッチングのScheduled MRMを設定する場合、同じsMRMモード(BasicモードまたはAdvancedモード)を選択する必要があることが説明されています。

10/04/2017   

MultiQuant™ ソフトウェアバージョン2.0 は、2.0ライセンスでは起動しません。

MultiQuant™ソフトウェア2.0のライセンスでは、MultiQuantソフトウェア2.0を起動できません。MultiQuantソフトウェア2.0.2、2.1、または2.1.1をインストールしてください。この記事には、そのことが記載されています。

10/03/2017   

SWATH®Acquisition で使用できるVariable Window Calculatorエクセルシートの使い方

この記事は、SWATH® AcquisitionにおけるVariable Windows の計算方法と、Variable Window Calculatorエクセルシートの作成方法について、段階的に説明しています。

10/02/2017   

A summary of the findings from an investigation into the identity of background Ions found in -ve mode electrospray mass spectrometry with suggestions to help minimize their impact on analysis.

10/02/2017   

Triple Quad或QTRAP的仪器灵敏度降低,可能意味着需要优化检测器CEM参数

Triple Quad或QTRAP的仪器灵敏度降低,可能意味着需要优化检测器CEM参数

09/29/2017   

Triple QuadまたはQTRAPの感度低下が見られた場合、CEM検出器のパラメータを最適化する必要があるかもしれません

この記事は、AnalystソフトウェアのCEM検出器パラメータを手動で最適化する方法について説明しています。適切でないCEM値によって引き起こされるトリプル四重極またはQTRAP装置の感度低下問題を解決する方法です。

09/29/2017   

1.6より以前のAnalyst®ソフトウェアバージョンでは、極性切り替え(Polarity Switching)はサポートされていません

極性切り替えでsMRMメソッドを実行するには、Analyst®ソフトウェア1.6以上を使用する必要があります。

09/26/2017   

MultiQuant™ソフトウェアでResults Tableを作成する時に表示されることがある「Incorrect Argument」エラー

この記事には、MultiQuant™ソフトウェアでResults Tableを作成する時に起こる「Incorrect Argument」エラーの解決策が記載されています。Analystソフトウェアから解析PCへデータを転送する場合は、個々のwiffやwiff.scanファイルだけを移すのではなく、プロジェクトごと移してください。

09/26/2017   

Sciex OSソフトウェアを起動すると常にライセンスアクティベーション画面が表示される

この記事には、Sciex OSを起動するたびに、ソフトウェアライセンスが正常にインストールされているにも関わらず、ライセンスアクティベーション画面が表示され続ける場合の解決策が記載されています。管理者権限でローカルにログインし、Sciex OSソフトウェアを再インストールすると、この問題は解決します。

09/20/2017   

ウイルス対策ソフトウェアSymantec v12.xは、Analyst®ソフトウェアによるデータ取得を妨げる可能性があります

この記事は、データ取得問題を引き起こす可能性のあるAnalyst®ソフトウェアとの競合を避けるためのウイルス対策ソフトウェアの設定方法についての説明です。Antivirusソフトウェアは、Analyst®ソフトウェア、Analyst TF、DiscoveryQuant™、Cliquid®、LightSight®、Reporter、およびMultiQuant™ソフトウェアなどの関連SCIEXソフトウェアプログラムによるデータ取得を中断する可能性があります。

09/18/2017   

Symantecのウィルス対策プログラムによって引き起こされるAnalyst®ソフトウェアのエラー : Failed to Write Method to Datafile

この記事には、Symantecのウィルス対策プログラムにおいてSonarテクノロジーを無効にすると、Analystソフトウェアの「Failed to write method to datafile」エラーを防ぐことができることが記載されています。

09/18/2017   

杀毒软件Symantec v12.x与Analyst等软件的数据收集产生冲突

杀毒软件有可能影响Analyst®,Analyst TF以及其他相关软件(例如DiscoveryQuant™, Cliquid®, LightSight®, Reporter以及 MultiQuant™ )的数据采集。本文将对如何防止杀毒软件和Analyst等软件产生冲突进行指导。

09/18/2017   

イオン源の排気(Exhaust)が詰まっているか浸水しているかどうかを確認する方法。原因と解決策

この記事は、排気(Exhaust)問題を診断する手順について説明しています。

09/13/2017   

ProteinPilot™ソフトウェア5.0.1はWindows 10と互換性はありますか?

この記事は、ProteinPilot™ソフトウェア5.0.1のWindows10への互換性に関して記載しています。ProteinPilot™ソフトウェア5.0.1はWindows10と互換性がありますか? いいえ、Windows 7、Service Pack 1、64ビットのみで動作します。

09/11/2017   

Analyst®ソフトウェア1.6.3のワークグループでRoot Directoryを選択する方法

この記事は、Analyst® ソフトウェア 1.6.3のワークグループでRoot Directoryを選択する方法について説明しています。ワークステーションをワークグループから削除し、再追加する必要があります。

09/11/2017   

ProteinPilot™ 5.0.1软件和Windows 10兼容吗?

ProteinPilot™ 5.0.1软件和Windows 10兼容吗?不,它只在Windows 7, Service Pack 1, 64-bit下运行

09/11/2017   

インターネットに接続されていないPCにおけるソフトウェアライセンスのアクティベーションとインストールの方法

インターネットに接続されていないPCにソフトウェアライセンスをインストールする必要がある場合は、そのPCのComputer IDを調べコピーし、インターネットに接続されたPCでライセンスのアクティベーションを行います。この記事には、その手順が記載されています。

09/11/2017   

PeakView®ソフトウェア1.2ライセンスコードの更新方法

この記事は、PeakView®ソフトウェア1.2において、ライセンスの有効期限が近づいていることを示すエラーメッセージが表示された場合について説明しています。ソフトウェアを再インストールし、新しいライセンスコードを取得する必要があります。

08/02/2017   

ProteinPilot™ソフトウェア5.0または5.0.1の検索中に発生するFraglet.exeエラーとは?

この記事は、ProteinPilot™ソフトウェア5.0または5.0.1のFraglet.exeエラーについて説明しています。原因の一つは、ProteinPilotを互換性のないOSにインストールした場合に発生することがあります。

07/14/2017   

AIDキーをダッシュ(「-」)なしで入力した場合、ライセンスキーが送信されません

ソフトウェアライセンスキーをオンラインでアクティベートする場合 (https://licensing.sciex.com/)、AID以降の4文字ごとにダッシュ(例:AID-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx-xxxx)を付けてライセンスキーを入力する必要があります。

07/14/2017   

QTRAP®システムのコリジョンガス(CAD)の機能は何ですか?

この記事は、QTRAP®システム装置におけるCollision Gas(CADガス)が様々なスキャンモードでどのように機能しているかの説明です。

07/14/2017   

MultiQuant™ソフトウェアのSimpleQueryの作成方法

この記事は、MultiQuant™ソフトウェアのSimple Queryの作成方法を説明したものです。[Process]メニューの[Create Simple Query]オプションを選択すると、簡単なクエリを作成できます。 計算式をCreate Query File画面に入力することができます。

07/14/2017   

ChemSpiderソフトウェアライセンスをPeakView®ソフトウェアで有効にする方法

この記事は、ChemSpiderのソフトウェアアクティベーション手順が段階的に説明されています。ChemSpiderは、PeakView®ソフトウェアのFormularFinder機能内で起動します。

07/10/2017   

MultiQuant™ソフトウェアをインストールする際に、Setup Cannot Continueエラーが表示される

MutliQuant™ ソフトウェアをインストールする際に、「Setup cannot continue until all system components have been successfully installed」とエラーメッセージが表示された場合、Windows 7 OSへのインストールが必要なのに、Windows 10 OSにインストールしている可能性があります。この記事には、システム情報の確認方法が記載されています。

06/29/2017   

インストール後にMultiQuant™ソフトウェアが起動しない場合

この記事は、MultiQuant™ソフトウェアをインストール後にソフトウェアが起動しない場合についてのヒントが記載されています。MultiQuant™ソフトウェアを正常にインストールしソフトウェアを初めて起動すると、ライセンスアクティベーション画面が表示されず、ライセンスをインストールすることができない場合があります。

06/21/2017   

MultiQuant™安装后无法运行

在成功安装MultiQuant™ 软件并且第一次启动软件时,license激活窗口没有显示,license文件无法安装。

06/21/2017   

在Windows 7下怎样保存应用与事件记录

Windows的事件记录包含SCIEX软件的重要信息。通过以下步骤保存事件记录以便SCIEX的支持团队进行分析。

06/15/2017   

Windows 7でApplicationやSystemのEvent Logを保存する方法

この記事は、Windows 7でApplication やSystemのEvent Logを保存する方法について説明しています。Event Logには、SCIEXソフトウェアのパフォーマンスに関する重要なデータが含まれていることがよくあります。SCIEXサポートチームが分析できるよう、この記事の内容に沿ってApplication やSystemのEvent Logを保存してください。

06/15/2017   

ソフトウェアIQ / OQテスト計画に関する詳細情報のお問い合わせ先

ソフトウェアバリデーションサービスの詳細については、complianceservices@sciex.comまで電子メールでご連絡ください。

06/09/2017   

关于软件的 IQ/OQ测试计划,我在哪里可以找到更多信息?

更多的关于软件认证的服务可以通过电邮complianceservices@sciex.com获取信息

06/09/2017   

MultiQuant™ソフトウェアにおける操作で、ULOQを超える濃度にどのようにフラグが付けられますか?

ULOQを超える濃度は、MultiQuant™ソフトウェアのResult Tableで、定量メソッドのCalculated Concentrationの上限を設定することにより、フラグを立てることができます。この記事は、その方法の説明です。

06/08/2017   

浓度高于ULOQ怎么让MultiQuant™软件进行标记?

在MultiQuant™软件中,可以通过设置浓度上限计算值来标记计算浓度超过ULOQ的样品

06/08/2017   

Analyst®TFソフトウェアでTOFのAcquisitionメソッドを作成する際のBin Sizeに関して考慮する点

この記事は、Analyst®TFソフトウェアでTOF MSシステムのAcquisitionメソッドを作成する際、「bin size」とは何を意味し、bin sizeを設定するための経験則について説明しています。

06/07/2017   

MultiQuant™ MD ソフトウェアをデスクトップのアイコンから起動できない

Analystソフトウェアのセキュリティ設定が「Integrated Mode」または「Mixed Mode」に設定されている場合、MultiQuant™ MDソフトウェアをデスクトップのアイコンから起動できません。Analystの「Companion Software」モードからMultiQuantを起動してください。セキュリティ設定を「Single User Mode」に変更すると、デスクトップからMultiQuant MDを起動することができます。この記事には、そのことが記載されています。

06/01/2017   

Analystのユーザー登録ポップアップウィンドウについて

この記事は、Analystのユーザー登録ポップアップウィンドウについて説明されています。Analystがインストールされたばかりでまだユーザー登録がされていない場合、Analystのユーザー登録ポップアップウィンドウが開き、登録キーを尋ねます。 この記事にそれを入手する場所が示されています。

05/31/2017   

怎样处理Analyst软件弹出的注册窗口

刚刚安装、还没有注册的Analyst软件弹出注册窗口。本文教你如何得到注册码。

05/31/2017   

AnalystソフトウェアのMRMのAcquisition Methodをマージする方法

この記事は、AnalystソフトウェアのMerge MRMスクリプトの入手、インストール、使用方法について説明しています。

05/31/2017   

LibraryView™ソフトウェアに新しいUserを追加する方法

この記事では、LibraryView™ソフトウェア1.0.xのSecurity Databaseに新しいUserを追加する方法について説明しています。ソフトウェアを開くには、Userを追加する必要があります。

05/31/2017   

SCIEX OS のGraph Selection Window が透けているのはなぜですか?

この記事には、SCIEX OS のGraph Selection Window が透けないようにする設定が記載されています。

05/31/2017   

对Analyst®软件推荐的计算机维护

为了使Analyst®软件流畅运行,有哪些计算机维护的方法?

05/26/2017   

Analyst®ソフトウェアのコンピュータメンテナンスに関する推奨事項

この記事は、Analyst®ソフトウェアを円滑に稼働させるためのコンピュータのメンテナンスについて説明しています。

05/26/2017   

サンプルリストをLipidomics Workflow Managerのプロジェクトにインポートできない

サンプルリストをLipidomics Workflow Manager 1.0.5に正常にインポートするには、Microsoft Office 2010とAccess 2007 Runtimeソフトウェアもインストールする必要があります。この記事には、そのことが記載されています。

05/25/2017   

MultiQuant™ソフトウェアでレポートを作成できない

この記事は、MultiQuant™ソフトウェアの[Create Report]オプションが[File]メニューに表示されない場合について説明しています。誤ったバージョンのMicrosoft Officeがインストールされている場合です。

05/17/2017   

MultiQuant™ 软件不能生产报告

由于安装了错误版本的Microsoft Office导致Create Report选项没有在MultiQuant软件中显示

05/17/2017   

MultiQuant™ソフトウェアのFileメニューでReport機能が表示されない場合

この記事は、MultiQuant™ソフトウェアの[File]メニューから[Report ]オプションが表示されない場合について説明しています。インストールされているMicrosoft Officeのバージョンが正しいことを確認してください。

05/04/2017   

TripleTOF™ 装置のIntact proteinスクリプト

この記事は、Intact Protein スクリプトについてまとめたものです。

05/03/2017   

PA800のクーラントチューブの交換方法

この動画は、PA800のクーラントチューブの交換方法について説明しています。

05/02/2017   

PA800 LIF Detectorの設置方法

この記事は、LIF Detectorの設置方法について説明しています。

05/02/2017   

PA800操作方法 - キャピラリーの取り外し方

この記事は、PA800のキャピラリーの取り外し方についての動画です。

05/02/2017   

PA800操作方法:エジェクタとエレクトロードの交換

この記事は、PA800システムのエジェクタとエレクトロードの交換方法についての動画です。

05/02/2017   

PA800操作方法 –キャピラリーのトリミングの仕方

この記事は、PA800システムのLIF アパーチャーとプローブスタビライザーの取り付け方を説明した動画です。

05/02/2017   

PA800操作方法:エジェクタとエレクトロードの取り外し方

この記事は、PA800システムのエジェクタとエレクトロードの取り外し方についての動画です。

05/02/2017   

PA800のカートリッジアパーチャ(Cartridge Aperture)の取り付け方法

この記事は、PA800システムのカートリッジアパーチャ(Cartridge Aperture)取り付け手順の動画です。

05/02/2017   

PA800操作方法 - 検出器の交換

この記事は、PA800システムの検出器の交換方法について説明した動画です。

05/02/2017   

PA800キャピラリーの保管方法

PA800システムのキャピラリーを保管する方法についての動画です。

05/02/2017   

PA800操作方法 - LIF Detectorの取り外し方

この記事は、PA800システムのLIF Detectorの取り外し方について説明した動画です。

05/02/2017   

PA800操作方法 - カートリッジの取り外し方

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

05/02/2017   

PA800操作方法 – LIF アパーチャーとプローブスタビライザーの取り付け方

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

05/02/2017   

PA800操作方法 – カートリッジの取り外し方、キャピラリーの交換、カートリッジの取り付け方

この記事は、PA800システムのカートリッジの取り外し方、キャピラリーの交換、カートリッジの取り付け方を説明した動画です。

05/02/2017   

Analyst1.6.3でバッチ処理が終了した後にLCポンプが稼働し続ける場合

この記事は、バッチが完了してもLCポンプが長時間オフにならない場合に、Queue OptionsでMax Idle Timeを確認する方法について説明しています。

04/27/2017   

Analyst 1.6.3中,进样序列(Batch)运行完毕但液相泵继续工作

如果进样序列已经运行完毕而液相泵却停不下来,这时需要调节Queue Options下面的Max Idle Time。

04/27/2017   

在Analyst中,怎样把普通MRM方法转换为Scheduled MRM方法?

想要把普通MRM方法转换为Scheduled MRM方法,需要在Analyst方法中更新保留时间。

04/25/2017   

AnalystのNon-scheduled MRMメソッドをScheduled MRMメソッドに変換する方法

この記事は、non-scheduled MRMメソッドをscheduled MRMメソッドに変換する方法について説明しています。Analystソフトウェアのメソッドで各トランジションの保持時間を入力する必要があります。

04/25/2017   

Sciex OS 1.2をインストール又はアップグレードする場合に考慮する点

この記事には、Sciex OS 1.2をインストール又はアップグレードする場合に、考慮する点について記載しています。Sciex OS 1.0やLibraryView Framework version 1.1や特定のコンパニオンソフトウェアもアンインストールしてください。

04/25/2017   

オートサンプラーで先行注入法を使用すると、HPLCのサイクルタイムを短縮することができます。この記事では、先行注入法を使用した場合の効果についての説明と先行注入法を使用せずに同じ結果を達成する方法について記載しています。

04/21/2017   

怎样编辑query扩展文件名?

要编辑query文件的扩展名,需要rename文件名。

04/13/2017   

プリカーサイオンIDA分析は、SCIEX TripleTOFシステムで実行できますか?

5600、5600+、6600、X500R、またはX500B、いずれのSCIEX TOF系装置では、プリカーサーイオンIDA測定を行うことができません。

04/13/2017   

母离子扫描IDA实验能在SCIEX TripleTOF中实现吗?

SCIEX的TOF仪器,包括5600, 5600+, 6600, X500R, 以及X500B,都不能做母离子扫描IDA。

04/13/2017   

. queryファイルの拡張子はどのように編集できますか?

.queryファイルの拡張子を編集するには、ファイル名を右クリックし「Rename(名前の変更)」を選択します。この記事は、そのことについて記載しています。

04/13/2017   

Description of how to use the Command Prompt of Windows XP to find the Computer ID used when licensing Sciex software.

04/07/2017   

Analyst: 怎样增加队列中样品数目的最大值?

队列样品数目最大值可以在Queue Options菜单下修改Max. Num. Waiting Samples设置。

04/04/2017   

Analyst:Queueのサンプル数の上限を増やす方法

この記事は、Queue画面にSubmitできるサンプル数の制限は、 [Queue Options]メニューの[Max. Num. Waiting Samples]に入力する数値により調整できることを説明しています。

04/04/2017   

DiscoveryQuant ソフトウェアを新規にインストールした場合、測定を開始するために確認する設定

この記事には、DiscoveryQuant(DQ)ソフトウェアを新規にインストールし、Acquity UPLCのインジェクションが開始されない場合に確認する設定について記載されています。確認する項目は、オートサンプラータイプの変更、新規Hardware Profileの作成、LCとMS間の通信の再確立、プレート位置の指定、Look Aheadタイプの注入を無効にする、です。

03/31/2017   

「Program Files」フォルダー内の保存先へ直接ライセンスファイルを保存し、MPXライセンスを再インストールする

この記事には、MPXドライバーソフトウェアライセンをスインストール中に、デスクトップに保存されているライセンスを受け付けない場合の対応策が記載されています。「Program Files」のMPXの「Bin」フォルダーにそのライセンスを保存してください。

03/31/2017   

Agilent Infiniti II HPLCとSCIEX 6500+システムの組み合わせ

この記事は、Agilent Infinity II HPLCシステムをSCIEX QTRAPまたはTripleQuad 6500+システムに接続し分析中に通信上の問題が発生した場合の対応策について説明しています。この記事の内容に沿い、Analyst® Device Driverから接続を確認し、新しいメソッドを構築します。

03/24/2017   

安捷伦Infiniti II高效液相色谱和SCIEX6500+系统

本文描述了当安捷伦Infiniti II高效液相色谱和SCIEX6500+系统在运行中发生联机问题时的解决方法。

03/24/2017   

MALDI TOFTOF: Batch測定において、リニアモードのAcquisition Methodを使用して較正できますか?

MALDI TOF/TOF装置のBatch測定において、リニアモードのAcquisition Methodで較正しようとすると、ソフトウェアはバッチ測定で較正する場合には、リフレクターモードのAcquisition Methodが必要であることを知らせてきます。この記事は、そのことについて記載しています。

03/24/2017   

How is a new hardware profile created that contains a 6500+ system and an Agilent Infinity II LC system that is using the Analyst Device Driver software?

03/23/2017   

X-シリーズQTOFシステムでのTuning Solutionの消費が早すぎる

X-シリーズQTOFシステムでTuning Solutionがすぐに空になる場合、Calibrant Delivery System(CDS)配管からの液漏れが原因である可能性があります。この記事では、その確認方法が記載されています。

03/21/2017   

ProteinPilot 検索でTrEMBL FASTA ファイルの使用を推奨しない理由

この記事には、ProteinPilotソフトウェアでTrEMBLデータベースを使用することを推奨しない理由が記載されています。TrEMBLデータベースは自動的にアノテーションが付けられ、レビュー(検証)されず、タンパク質配列、タンパク質アクセッションナンバーなどに関して冗長性が含まれる可能性があるからです。

03/21/2017   

自動最適化(Compound Optimization)で作成されるメソッドはどれですか?

Analyst1.6.3で複数の化合物を自動最適化(Compound Optimization)すると、全てのMRMトランジションの最適化条件を含む1つのFinal MRM Methodが作成されます。作成されたFinal MRM Methodの情報は、自動最適化(Compound Optimization)レポートの最後に表示されます。この記事は、そのことについて説明しています。

03/20/2017   

保持時間のシフトおよびポンプ圧力変動に関するトラブルシューティング

この記事は、Shimadzu NexeraおよびEXION AD HPLCポンプで流速試験を実施し、不適切なポンプ流量の場合、一般的な原因をトラブルシューティングする手順です。

03/20/2017   

重启电脑,高效液相色谱和质谱来解决通讯问题

重启电脑,高效液相色谱和质谱可以解决通讯问题

03/20/2017   

通信問題を解決するためにPC、HPLC、およびMSの電源を入れ直してください。

この記事は、通信の問題を解決するためにLCMS装置の電源の入れ直しを実行してもらうための説明です。

03/20/2017   

ProteinPilotソフトウェアが解析に使用するコア数はいくつですか?

ProteinPilotソフトウェアが解析に使用するコアの数は、ライセンスファイルに定義されています。この記事には、ライセンスファイルに定義されているコア数の確認方法が記載されています。

03/16/2017   

ESTや他のヌクレオチドのデータベースをProteinPilotソフトウェアの検索に使用する方法

ESTやその他のヌクレオチドのデータベースをProteinPilotソフトウェアの検索に使用するには、データーベースの翻訳が必要です。この記事には公開されている、翻訳ツールの例が記載されています。

12/07/2016   

ProteinPilot 软件 fraglet.exe CHEMICAL EXCEPTION的错误

ProteinPilot 软件 fraglet.exe CHEMICAL EXCEPTION的错误

12/07/2016   

MasterViewのライブラリーをバックアップまたは移動する方法

この記事は、MasterViewのライブラリーをバックアップまたは移動する方法について説明しています。

12/07/2016   

仮想メモリ不足の警告について

この記事は、仮想メモリが不足しているという警告が表示された場合について説明しています。ページングファイルの最小サイズを増やす必要があります。

12/07/2016   

ProteinPilotのエラー:「fraglet.exe - CHEMICAL EXCEPTION」

この記事は、ProteinPilotのエラー:「fraglet.exe - CHEMICAL EXCEPTION」について記載しています。

12/07/2016   

如何备份与移动MasterView谱库

本文描述了如何备份与移动MasterView谱库

12/07/2016   

虚拟内存不足的警告

如果你收到关于虚拟内存不足的警告,你需要增加最小页面文件值。

12/07/2016   

ProteinPilotのParameterTranslationファイルまたはProteinPilotDataDictionaryファイルに加えた編集をリセットしオリジナルのファイルに戻す方法

この記事には、ProteinPilotソフトウェアのParameterTranslation.xmlファイルまたはProteinPilotDataDictionary.xmlファイルに誤った編集を加えたり、編集した箇所がわからなくなり、ファイルをオリジナルに戻したい場合のやり方が記載されています。

10/07/2016   

iTRAQ RatioをレポートするためのMass Tolerance値やThreshold値はParameter Translationファイルに設定されています。

この記事には、iTRAQ RatioをレポートするためのMass Tolerance値とThreshold値が、Parameter Translationファイルに設定されていることが説明されています。

10/07/2016   

ProteinPilotエラー:fraglet.exe not wellformed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71

Description:ProteinPilot gives the error fraglet.exe not wellformed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71 この記事には、ProteinPilotのエラー「fraglet.exe – not well-formed (invalid token) at line 1 and position 33112not well-formed (invalid token) at line 3 and position 71」が表示された場合の解決策が記載されています。

10/07/2016   

UPLCを使用する場合、Eksigent Nano IIIイオン源のフィッティングは背圧に耐えることができますか?

この記事には、UPLCを使用する場合に、Eksigent Nano IIIイオン源のフィッティングが背圧に耐えられるかどうかについて記載されています。最大10,000 psiの背圧に耐えることができます。

10/07/2016   

在Skyline中为Analyst创建方法时怎样避免无效的列表格式错误

描述无效的transition列表格式原因

10/07/2016   

4700データを使用してt2dファイルをmzxmlファイルに変換できますか?

この記事は、「4700データを使用してt2dファイルをmzxmlファイルに変換できますか?」という質問にコメントしたものです。

10/07/2016   

Ekspert™ 400 液相系统 – 更换流动相

本文描述了如何为Ekspert™ 400 液相系统更换流动相

10/07/2016   

SkylineでAnalystのメソッドを構築する際、「Invalid transition list format 」というエラーが発生しないようにする方法

SkylineでAnalystのメソッドを構築する際、「Invalid transition list format」というエラーが表示されることがあります。この記事は、その原因と回避策について記載しています。

10/07/2016   

4700のデータをProteinPilot ソフトウェアで解析できますか?

この記事には、4700のデータをProteinPilotソフトウェアで解析できるかどうかについて記載されています。ProteinPilot ver3.0で解析することができますが、このバージョンは既に販売が廃止されており、使用することができません。

10/07/2016   

Nano2D LC Eksigentポンプシールリンスとオートサンプラ洗浄に使用する溶媒について

この記事は、 EksigentNano2D LCポンプのシールウォッシュとオートサンプラ洗浄に使用する溶媒について説明しています。

10/07/2016   

Ekspert™ 400 LCシステム における 移動相の交換方法

この記事は、Ekspert™ 400 LCシステムにおける、移動相の交換方法について説明しています。

10/07/2016   

ProteinPilot の.groupファイルのピークがセントロイドになる理由

この記事には、ProteinPilot の.groupファイルのピークがセントロイドになる理由が記載されています。

10/07/2016   

ProteinPilot 错误信息为“fraglet.exe not well-formed invalid token at line 1 and position 33112not wellformed invalid token at line 3 and position 71”

ProteinPilot 有以下错误信息 “fraglet.exe – not well-formed (invalid token) at line 1 and position 33112not well-formed (invalid token) at line 3 and position 71”

10/07/2016   

iTRAQ 4Plexおよび8Plexのプロトコールを実行する際、イソプロパノールの替わりにエタノールを使用できますか?

iTRAQ 4Plexおよび8Plexのプロトコールを実行する際、イソプロパノールの替わりにエタノールを使用できます。この記事は、そのことが記載されています。

10/07/2016   

Eksigent Nano Tempo Classicでのピーク溶出の遅れ

この記事には、Eksigent Nano Tempo Classicでのピーク溶出の遅れの一般的な二つの原因とその解決策について記載されています。

10/07/2016   

Eksigent Nano III离子源接头配件能否在UPLC反压下工作?

Eksigent Nano III离子源接头配件能否在UPLC反压下工作?

10/07/2016   

背圧が高い時に、Eksigent Nano Chrom XP C18カラムの向きとは逆向きに液を流してもいいですか?

背圧が高い時に、Eksigent Nano Chrom XP C18カラムの向きとは逆向きに通液しないでください。この記事には、そのことが記載されています。

10/07/2016   

4700的数据能把t2d格式转换为mzxml吗?

4700的数据能把t2d格式转换为mzxml吗?

10/07/2016   

AnalystソフトウェアのBatch画面でbatch dataが[DAB Sever Error]で開かない場合

この記事は、Analyst バッチをファイルからインポートするとインポートが失敗し、「Error Could not open the batch data DAB Sever Error」というエラーメッセージが表示されバッチを開くことができない場合の解決策について説明しています。

09/04/2016   

LibraryViewソフトウェアへログインできない場合

この記事には、LibraryViewソフトウェアへログインできない場合の解決策が記載されています。

09/04/2016   

DiscoveryQuant 2.1.xから使用しないテンプレートを削除する方法

この記事には、DiscoveryQuant のAnalyzeのセットアップ画面から使用しないテンプレートを削除する方法が説明されています。

09/04/2016   

怎样打印PeakView中的XIC Manager列表

本文介绍了打印PeakView中的XIC Manager列表的方法

09/04/2016   

Ekspert 400 AS3 のエラーメッセージ:Pump volume is not sufficient to run LC method without a restroke.

この記事には、Ekspert 400 AS3でエラーメッセージ、「Pump volume is not sufficient to run LC method without a restroke」が表示される理由と対応策が記載されています。

09/04/2016   

在MultiQuant结果表中怎么导出相关系数r

文章介绍了如何在MultiQuant结果表中导出相关系数r。此功能仅在MultiQuant 3.0.1 版本可用。

09/04/2016   

PeakViewのXICManagerからリストを印刷する方法

この記事は、XIC Managerからリストを印刷する方法について説明しています。

09/04/2016   

相関係数rをMultiQuantのResults Tableから出力する方法

この記事は、MultiQuantのResults Tableから相関係数rを出力する方法について説明しています。MultiQuantバージョン3.0.1以降で使用できます。

09/04/2016   

Win XPのコンピューター IDの確認方法

この記事には、Windows XPのコマンドプロンプトを使用して、Sciexソフトウェアのライセンスを取得する時などに必要なコンピューターIDを確認する方法が記載されています。

09/04/2016   

Ekspert 400 AS3のエラーメッセージ: ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED

この記事は、Ekspert 400 AS3 のエラーメッセージ「ERROR SAMPLE-NEEDLE VIALBOTTOM ACTIVATED」が表示される原因について記載しています。

09/04/2016   

Amplifier Resetのトラブルシューティング

Amplifier Resetアラートは、ポンプが空になり、Rifill(補充)されたことを意味します。ポンプの容量は有限であるため、長時間または高流量で送液する場合、Rifill(補充)が行われます。Amplifier Resetはアラートであり、エラーではありません。Amplifier Resetが実行されると、ポンプは補充され、プログラムされた速度でポンプが流れ続けます。Amplifier Resetしても、サンプルバッチまたはキュー(Queue)は停止しません。Amplifier Resetが発生したことを示す警告メッセージが表示された場合は、最初に、これが自然なリセットかどうかを確認します。この記事では、Amplifier Resetの原因を特定する手順を説明しています。

09/04/2016   

Analyst で表示される「Project」のドロップダウンリストがアルファベット順に表示されない

この記事は、Analystで表示される「Project」のドロップダウンリストがアルファベット順に表示されない理由について記載しています。

09/04/2016   

ProteinPilot 4.5bのインストールおよびProteinPilot 4.0からProteinPilot 4.5bへのアップグレード方法

この記事は、ProteinPilotソフトウェア4.5βのアンインストールとインストール手順の説明です。

09/04/2016   

含有页脚的Reporter 3.0.1报告模板转换为Reporter 3.2时出错

Reporter 3.0.1报告模板转换为Reporter 3.2时出错

09/04/2016   

Reporter 3.0 .1からReporter 3.2へのレポートテンプレートの変換は、ドキュメントのフッターに情報が含まれていると、うまくいきません。

Reporter 3.0.1のxmlファイルをReporter 3.2のdocxファイルへ変換する際に、xmlテンプレートにフッター情報が含まれていると変換がうまくいかない場合があります。この記事には、その回避策が記載されています。

09/04/2016   

登录LibraryView软件失败

登录LibraryView软件失败

09/04/2016   

在Windows XP下寻找电脑识别码(Computer ID)

本文描述了如何用Windows XP的cmd来寻找电脑识别码,用于注册SCIEX软件

09/04/2016   

Analyst Projects下拉列表不是按照字母顺序排列

Anlayst Projects 下拉列表不是按照字母顺序排列

09/04/2016   

June2010 Hotfixesの有無に関わらず、Analyst1.5.1の操作において、AAO (Analyst Access Objects)ドライバーによりHPLC設定を構築されたメソッドでBatchからデータを取得しようとすると失敗する場合

この記事は、Analyst 1.5.1で150以上のトランジションがある場合に、AAO制御の HPLCデバイスを含むメソッドでデータを取得するための要件について記載しています。

09/04/2016   

アーカイブを作成した時よりも新しいバージョンのAnalystソフトウェアで監査証跡アーカイブ(Audit Trail Archives)を開くことが推奨されない理由

Analystソフトウェアの監査証跡(Audit Trail)ファイルを開いたり、読み込んだりする時は、取得した時と同じバージョンのAnalystソフトウェアでのみ実行してください。この記事は、そのことについて記載しています。

09/04/2016   

Analyst 软件进样序列编辑器中 Could not open the batch data DAB Server Error的错误

从文件向Analyst导入进样序列时,出现 Could not open the batch data DAB Server Error 错误

09/04/2016   

Analyst TF 1.6ソフトウェアのInclude/Excludeリストに入力できる数について

この記事は、Analyst TF 1.6ソフトウェアのInclude/Excludeリストに入力できる数の制限について記載されています。上限は、32767です。

07/08/2016   

Network Acquisition用にAnalyst®ソフトウェアを設定する方法

この記事は、Analystソフトウェアを使用してネットワーク経由でデータを取得する設定方法について説明しています。ネットワーク経由によるデータ取得は、データの完全なバックアップセキュリティやアクセスの目的から非常に役立ちます。 

07/08/2016   

Mascot.dll脚本能在win 7 Analyst 1.6上工作吗

定义了关于运行这个脚本的问题和解决办法

07/08/2016   

Cliquid 3.2で利用できるレポート形式がありません

この記事には、Cliquid 3.2を新規インストール後にレポート形式の作成または選択ができない場合の解決策が記載されています。

07/08/2016   

ConfigUpdater.exe 不能升级仪器固件

Windows防火墙的拦截导致ConfigUpdater不能升级仪器固件

07/08/2016   

Mascot.dll スクリプトは、Win7 PCにインストールされたAnalyst1.6で使用できますか?

この記事には、Mascot.dllスクリプトの使用に必要なデータ条件が記載されています。

07/08/2016   

怎样设置Analyst®软件网络数据采集

出于数据备份和获取的需求及网络安全原因,网络数据采集非常有用。这里介绍怎样设置Analyst的网络数据采集。

07/08/2016   

64-bit PCにインストールされたMultiQuant 2.1.1で、レポートオプションが表示されない

64-bit版のMicrosoft Officeがインストールされていない場合、64-bit版 OS上のMultiQuant 2.1.1では、レポートオプションが表示されません。この記事には、その解決策が記載されています。

07/08/2016   

印刷されたレポートにクロマトグラムが表示されない、リンクされた画像が表示できない場合

この記事には、多数のクロマトグラムを含むレポートを作成する時、印刷されたレポートに画像が表示されない場合に確認する設定について記載されています。

07/08/2016   

Win7 64-bit PCでEksigent 3.12.1ソフトウェアを使用できますか?

この記事は、Eksigent 3.12.1ソフトウェアをWindows 7 64-bit PCで使用するための設定に関して記載しています。

07/08/2016   

データをダウンロードする時のMarkerView 1.2.1 のエラー :「Could not get method information for A1_MS_1.t2d 」

この記事には、データをダウンロードしようとした時に出るMarkerView 1.2.1のエラー「Could not get method information for A1_MS_1.t2d」についての解決策が記載されています。

07/08/2016   

Analyst 1.6.xがインストールされたPCでレポーター を実行すると「Unexpected error has occurred」が表示される場合

この記事には、Analyst 1.6.xがインストールされたPCでレポーター を実行すると「Unexpected error has occurred」が表示される原因と解決策が記載されています。

07/08/2016   

Analystソフトウェアでデータ取得中にLibraryViewソフトウェアを操作すると、Analystソフトウェアはデータの取得を停止させる可能性があります。

Analystソフトウェアでデータ取得中にLibraryViewソフトウェアを操作すると、Analystソフトウェアはデータの取得を停止してしまう可能性があるため、同時に実行することはお勧めできません。この記事には、そのことが記載されています。

07/08/2016   

色谱图不能在打印报告中显示

在生产含有色谱图的报告时,在大量图谱生成后图像关联不能被显示的问题

07/08/2016   

ConfigUpdater.exeが装置のファームウェアを更新できない場合

この記事は、ConfigUpdater.exeが装置のファームウェアを更新できない場合について説明しています。Windowsファイアウォールの問題で、ConfigUpdaterによるイーサネット接続されている装置のファームウェアの更新が妨げられます。

07/08/2016   

「Manually Integrate」スクリプトがインストールされているのに、スクリプトを実行すると、スクリプトがインストールされていないことを示すエラーメッセージが表示されます。

script an error message appears saying that the script is not installed. この記事には、Windows7 OSに「Manually Integrate」スクリプトがインストールされており、スクリプトを実行すると、スクリプトがインストールされていないことを示すエラーメッセージが表示される場合の回避策が記載されています。

07/08/2016   

MultiQuantソフトウェアでsMRM(Scheduled MRM)データを解析するには、sMRM対応機能が追加されたライセンスが必要です。

Description:Scheduled MRM not supported in Multiquant you do not have the required license to open files containing scheduled MRM data MultiQuantソフトウェアでsMRM(Scheduled MRM)データを解析するには、sMRM対応機能が追加されたライセンスが必要です。この記事には、そのことが記載されています。

07/08/2016   

SCIEXのソフトウェアがインストールされているWindows 7デスクトップにおいて、Windows 10アップグレードを防止する方法

この記事は、SCIEXのソフトウェアがインストールされているコンピューターにおいて、 Windows 7からWindows10へのアップグレードを防止する方法について説明しています。マイクロソフトでは、ユーザーがWindows 7 OSからWindows 10 OSにアップグレードすることを強く求めています。 これにより、不要なアップグレードや偶発的なアップグレードが発生する可能性があります。 2016年7月現在、SCIEXソフトウェア製品の一部はWindows 10 OSで完全にテストされていません。したがって、SCIEXソフトウェアの一部の製品はWindows 10 OSでは正常に動作することは確認できていません。

07/05/2016   

Chemoview 2.0.2生成Excel报告时出现下面错误信息Programmatic Access to Visual Basic Project is not trusted

当Chemoview 2.0.2生成excel报告时产出错误,信息为“Programmatic Access to Visual Basic Project is not trusted”

06/02/2016   

Cliquid エラー: Retrieving the COM class factory for component with CLSID

この記事は、Cliquidソフトウェアにおいて、Error: Retrieving the COM class factory for component with CLSID {36977493-A670-11Dc-8Dcc-00104BC5f89A}…というエラーメッセージがウィンドウの下部に表示された場合の解決策について記載されています。

06/02/2016   

Application Event Log エラー - Analyst Event ID - 2 - Category FMAN [CompDocDrvDLL][Error][File: CreateOpenCompDoc.cpp][Line 569]

この記事は、ネットワーク取得(Network Acquisition)で引き起こされる、あるApplication Event Log エラーの原因について説明しています。

06/02/2016   

Windows 7でオペレーティングシステムのロケールを確認する方法

この記事は、システムのロケールを正確に確認するプロセスの説明です。SCIEXソフトウェアは、(リリースノートに別途記載がない限り)en-US United Statesのロケールを持つシステムでのみサポートされています。 

06/02/2016   

用Aglient液相,能否显示压力曲线

本文介绍了如何在安捷伦液相的硬件profile中激活压力曲线

06/02/2016   

マルチページの印刷、後続のページが最初のページと同じになる

ローカルユーザープロファイルが破損していると、Analystでは、マルチページからなるドキュメントを正しく印刷できない場合があります。この記事には、その場合の解決策が記載されています。

06/02/2016   

如何查找Windows7系统所在区域

SCIEX的软件(除非在release notes里面说明)只能在系统区域为英语-美国(en-US)下运行。本文介绍了如何确认系统区域。

06/02/2016   

Waters Acquity HPLCシステムで使用するSCIEX AUXIOケーブルの配線図

この記事には、Waters Acquity HPLCシステムで使用するAUXIOケーブルの配線図が示されています。

06/02/2016   

Cliquid错误:Retrieving the COM class factory for component with CLSID

Cliquid软件可以成功地运行样品但是无法处理他们,并且会在窗口下方报告错误:Retrieving the COM class factory for component with CLSID {36977493-A670-11Dc-8Dcc-00104BC5f89A}…

06/02/2016   

AnalystとAgilent LCシステムを使用してクロマトグラムの圧力カーブを表示することはできますか

この記事は、Agilent LCシステムを使用している場合、ポンプの圧力カーブを表示するためのHardware Profileの設定方法について説明しています。

06/02/2016   

Waters Acquity Method Editor v1.4 & 1.5で「Unhandled exception has occurred」エラーが出た場合

この記事は、Waters Acquity Method Editorでメソッドを保存または開く時に、「unhandled exception occurs System.NullReferenceException Object reference not set to an instance of an object」エラーが出た場合の解決策について説明しています。

06/02/2016   

ChemoView 2.0.2でエクセルレポートを作成しようとすると「Programmatic Access to Visual Basic Project is not trusted」というメッセージが表示され、レポートが作成されない

Chemoview 2.0.2でエクセルレポートを作成しようとすると、レポートが作成されず、レポートプレビューに「Programmatic Access to Visual Basic Project is not trusted」というメッセージが表示されることがあります。この記事は、その解決策について記載しています。

06/02/2016   

5500シリーズ質量分析装置の電源やポンプを止め真空を解除する方法

この動画は、電源やポンプを止め真空を解除する方法とその後装置を復帰させる操作手順について説明しています。

02/05/2016   

島津(Shimadzu)のHPLCを含むAnalyst®ソフトウェアのAcquisition Method(.dam)の作成方法

この動画は、ShimadzuのHPLCを使用する場合のAnalyst Acquisition Method(.dam)の作成操作手順を説明しています。

02/05/2016   

Turbo V™イオン源ヒーターの交換方法

この動画は、Turbo Vイオン源ヒーターの交換方法の手順について説明しています。

02/05/2016   

TripleTOF® システムの電源の切り方と起動のさせ方

この記事は、TripleTOFシステムの電源の切り方と起動のさせ方についての動画です。

02/05/2016   

Analyst®ソフトウェアにおけるサンプルバッチ(Batch)のSubmitと測定のスタート方法

この記事は、Analystソフトウェアでサンプルバッチ(Batch)をSubmitする方法と測定をスタートする方法について説明した動画です。

02/05/2016   

SCIEX 5500&6500システムにおける Diverter Valve(切り替えバルブ)の設定方法

この動画は、5500と6500シリーズのロータリーポンプのオイル交換操作手順について説明しています。

02/05/2016   

TripleTOF®システムにおける、真空を落とさないインターフェイスの定期クリーニング

この記事は、TripleTOFシステムにおける、真空を落とさないインターフェースの洗浄方法についての動画です。

02/05/2016   

Instrument Optimizationを使用した4500、5500、および6500のTuning操作

この動画は、Instrument Optimizationの操作手順を説明しています。

02/05/2016   

切り替えバルブの設定方法

この動画は、SCIEX 5500&6500システムにおける Diverter Valveの設定方法について説明しています。

02/05/2016   

AgilentのHPLCを含むAnalyst®ソフトウェアのAcquisition Method(.dam)の作成方法

この動画は、AgilentのHPLCを使用する場合のAnalyst Acquisition Method(.dam)の作成操作手順について説明しています。

02/05/2016   

MultiQuantクエリをデバッグする方法

この記事は、MultiQuantクエリをデバッグモードに設定する方法を説明したものです。MultiQuantクエリを作成するときに、クエリで実行される計算を確認すると便利なことがあります。MultiQuantクエリをデバッグモードに設定すると、Excelで作成されたファイルを表示し、計算のエラーを修正することができます。

12/22/2015   

DiscoveryQuant™3.0用SQL Server 2014のインストール方法

この記事は、DiscoveryQuant 3.0で使用するSQL Serverを構築するプロセスについて説明したものです。

12/22/2015   

我如何对MultiQuant Queries进行调试

在写MultiQuant query的时候经常需要看到query的计算方法。当把MultiQuant query设置成调试(debug)模式你就可以看到excel生成的文件并可以对算法进行纠错。

12/22/2015   

Analyst ソフトウェアのセキュリティー設定の記録を作成する方法

この記事は、Analystソフトウェアからセキュリティー設定を印刷またはPDFファイルに記録する方法について説明しています。

12/22/2015   

ChemoView设置的导入与导出

ChemoView设置可以导出,以便备份与转移到其它计算机中。

12/22/2015   

在Analyst软件中怎样创建安全设置记录

本文解释了在Analyst工作站中使用打印模式或PDF模式输出安全设置的方法

12/22/2015   

ChemoViewソフトウェアの設定をエクスポートおよびインポートする方法

ChemoViewソフトウェアの設定をエクスポートし、インポート機能を使い装置やコンピュータ間でバックアップや転送ができます。この記事は、そのエクスポートやインポートの方法について説明しています。

12/22/2015   

如何将.wiff转换为NetCDF格式

本文解释了如何用Analyst软件自带的Translat.exe将.wiff转换为NetCDF格式

10/02/2015   

.wiffをNetCDF形式に変換する方法

この記事は、Analystソフトウェアに含まれているTranslat.exeプログラムを使用して.wiffファイルをNetCDFに変換する方法について説明しています。

10/02/2015   

Windows 7系统中安装Multiquant 3.0.x,在步骤中出现.NET Framework 3.5 SP1之后安装失败

Windows 7系统中安装Multiquant 3.0.x,在步骤中出现.NET Framework 3.5 SP1之后安装失败

10/01/2015   

在Analyst软件定量时出现Unspecified error错误

在Analyst软件定量时出现Unspecified error错误

10/01/2015   

在Analyst中怎样改变回归方程的科学记数法

本文描述怎样在Analyst中怎样改变回归方程的科学记数法

10/01/2015   

Analystソフトウェアのエラー:Analyst.exe - Unable To Locate Component pt95FKn71.dll

Analystを起動するか、Hardware Profileをアクティべートすると、「Analyst.exe - Unable To Locate Component ;This application has failed to start because pt95Fkn71.dll was not found.  Re-installing the application may fix this problem.」というメッセージが表示される場合があります。この記事には、その解決策が記載されています。

10/01/2015   

MarkerView与Microsoft Office 2013出报告时出现This method or property is not available for reading的错误

Markerview 1.2.1 结合 Microsoft Office 2013 生产报告时产生This method or property is not available because this command is not available for reading错误解决方法

10/01/2015   

LibraryView 1.0 のエラー : Error 21467259 failed to create SQL database Unknown Error

この記事は、LibraryView 1.0インストール時に表示されるエラーメッセージについて説明しています。次のエラーメッセージ 「Error 21467259 failed to create SQL database LibraryView error detail Unknown Error.」が表示される場合の解決方法についてです。

10/01/2015   

由于当前用户不在security database的原因导致不能运行Analyst软件

This is a known issue in the ProteinPilot™ software 5.0.2 and was resolved with a patch.

10/01/2015   

AnalystソフトウェアでS/N(Signal to Noise)を算出する方法

この記事は、Analyst ソフトウェアでExploreモードまたはQuantitateモードを使用してS/N(Signal to Noise)を測定する方法について説明しています。

10/01/2015   

Windows 7环境中Analyst在Explore定量模式下停止工作而崩溃

Windows 7环境中Analyst 1.6.x停止工作并且显示“AB Sciex Analyst has stopped working” 错误指示。这个情况经常出现在鼠标箭头与色谱图上移动的时候。

10/01/2015   

Analystにおける検量線の回帰方程式の有効数字を変更する方法

この記事は、Analystにおける検量線の回帰方程式の有効数字の変更方法について説明しています。

10/01/2015   

MarkerViewとMicrosoft Office 2013の組み合わせで「This method or property is not available because this command is not available for reading.」この様なメッセージが出た場合

この記事は、MarkerView1.2.1とMicrosoft Office 2013の組み合わせで「This method or property is not available because this command is not available for reading.」この様なメッセージが出た場合の解決策について説明しています。

10/01/2015   

DiscoveryQuantの Quick Tune でDP値がゼロに設定される DPスキャン問題

この記事には、DiscoveryQuant 2.1 .3 のQuick Tuneを実行するとDP値がゼロに設定され、正しくないDP値によりFine Tuneが失敗する場合の解決策が記載されています。Quick Tune用のQ3 MIスキャンメソッドによる2回のDPスキャンでは、2回ともDP 200v(ただし、この電圧は変化する場合があります。)でMH+イオンが検出されています。装置の「Parameter settings」のDP値の範囲を見直してください。

10/01/2015   

AnalystソフトウェアのQuantitateモードにおいて発生することがある「Unspecified error」

この記事は、AnalystソフトウェアのQuantitateモードで新しいバッチを解析しようとした時に表示される「Unspecified error」メッセージの解決方法について説明します。

10/01/2015   

DiscoveryQuant のOptimizeでエラーメッセージ「Cannot set spectrum for experiment X」が表示されて最適化が完了しない

この記事には、DiscoveryQuantのOptimizeで、エラーメッセージ「Cannot set spectrum for experiment X」が出て、最適化が完了しない場合の対応策が記載されています。プロファイルを作成するのに充分なスキャン数が取得できていないことが原因である可能性が高いです。いずれかの方法で、Experimentのデータポイント数を増やしてください。

10/01/2015   

Windows 7へのMultiQuant 3.0.xのインストールが「.NET Framework 3.5 SP1」のメッセージが表示されて失敗する場合

Windows 7OSにMultiQuant 3.0.xソフトウェアをインストールすると、.NET Framework 3.5 SP1をインストールするかどうかをユーザーに確認した後、インストールが停止する場合があります。この記事は、その解決策を説明しています。

10/01/2015   

「The Analyst application cannot be started because the current user is not in the security database. 」この様なメッセージが出た場合

Analystを起動し、「The Analyst application cannot be started because the current user is not in the security database. 」とメッセージが出た場合は、現在のユーザーがセキュリティデータベースにないか、ユーザータイプが割り当てられていないため、Analystアプリケーションを開始できません。 ネットワークが利用できない場合も、このメッセージが表示される場合があります。 管理者に連絡してください。

10/01/2015   

Windows 7にインストールされているAnalystソフトウェアのExploreやQuantitateモードで操作中「AB Sciex Analyst has stopped working」と表示され操作が停止した場合

この記事は、Windows 7でAnalystバージョン1.6.xを使用している場合「AB Sciex Analyst has stopped working」というメッセージを表示して停止する場合の解決策について説明しています。これは通常、マウスカーソルがクロマトグラムペインを横切って移動したときに発生します。

10/01/2015   

Reporter 3.0.1テンプレートファイルには、WordでサポートされていないカスタムXML要素が含まれています。

この記事は、Microsoft Word 2007 SP1でReporter3.0.1の XMLテンプレートを開くと、エラーメッセージ「The file contains custom XML elements which are no longer supported by Word.If you save this file these custom XML elements will be removed permanently」が表示される場合についてコメントしています。

10/01/2015   

在Analyst软件中怎样计算信噪比

本文介绍了如何在Analyst软件中的Explore或者Quantitate模式下计算信噪比

10/01/2015   

「Visual C 2010 Runtime Librariesx86」をインストールできず、Cliquid 3.2またはMultiQuant 2.1のインストールに失敗する場合

この記事には、Cliquid 3.2またはMultiQuant 2.1のインストール時に「Component Visual C 2010 Runtime Librariesx86 has failed to install with the following error message Asia. 」と表示され、Visual C 2010 Runtime Libraries x86をインストールできず、Cliquid 3.2またはMultiQuant 2.1のインストールに失敗する場合の対応策が記載されています。

10/01/2015   

LibraryView 1.0 创建SQL时出现的 21467259 错误

安装LibraryView 1.0 时出现的 21467259 错误:Error -21467259: failed to create SQL database: LibraryView, error detail: Unknown Error

10/01/2015   

Analyst.exe Unable To Locate Component pt95FKn71.dll的错误

运行Analyst激活硬件Profile时,出现“Analyst.exe - Unable To Locate Component' with message body 'This application has failed to start because pt95Fkn71.dll was not found.  重新安装软件可以解决这个问题。

10/01/2015